Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1491 produtos de "Autofagia"
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Lycorine hydrochloride
CAS:Lycorine hydrochloride (Narcissine hydrochloride) is VE-cadherin inhibitor,and has IC50 of 1.2μM in Hey1B cell.It is an HCV inhibitor with strong activity.Fórmula:C16H18ClNO4Pureza:99.45% - 99.49%Cor e Forma:Fine Crystal PowderPeso molecular:323.77Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Fórmula:C33H45ClN4O9Pureza:98.22% - >99.99%Cor e Forma:Pale Yellow To Yellow Crystalline PowderPeso molecular:677.18Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Fórmula:C20H21N5O6Pureza:98.1% - 99.92%Cor e Forma:Similar To White PowderPeso molecular:427.41Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Fórmula:C15H22N2OPureza:99.55%Cor e Forma:SolidPeso molecular:246.35Maprotiline hydrochloride
CAS:Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.Fórmula:C20H24ClNPureza:99.68% - 99.84%Cor e Forma:White PowderPeso molecular:313.864Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:White PowderPeso molecular:437.52Ref: TM-T0097L
10mg47,00€25mg70,00€50mg90,00€100mg138,00€200mg225,00€500mg314,00€1mL*10mM (DMSO)56,00€Trifluoperazine dihydrochloride
CAS:Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Fórmula:C21H26Cl2F3N3SPureza:99.57% - 99.96%Cor e Forma:Cream Fine PowderPeso molecular:480.43Erythromycin ethylsuccinate
CAS:Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.Fórmula:C43H75NO16Pureza:77% - 98%Cor e Forma:White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline SolidPeso molecular:862.05Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Xylitol
CAS:Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.Fórmula:C5H12O5Pureza:99.89% - 99.96%Cor e Forma:White Solid PowderPeso molecular:152.15Monacolin J
CAS:Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.Fórmula:C19H28O4Pureza:98.06%Cor e Forma:SolidPeso molecular:320.42Ref: TM-T12092
1mg74,00€5mg152,00€10mg222,00€25mg376,00€50mg537,00€100mg777,00€1mL*10mM (DMSO)161,00€Fluoxetine
CAS:Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Fórmula:C17H18F3NOPureza:99.07% - 99.28%Cor e Forma:SolidPeso molecular:309.33Bromhexine hydrochloride
CAS:Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.Fórmula:C14H21Br2ClN2Pureza:99.98%Cor e Forma:White SolidPeso molecular:412.59Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.73%Cor e Forma:Light Tan To Yellow PowderPeso molecular:244.24Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46Salicylic acid
CAS:Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Fórmula:C7H6O3Pureza:98.04% - 98.83%Cor e Forma:White Solid PowderPeso molecular:138.12Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Fórmula:C21H27ClN2S2Pureza:99.55% - 99.957%Cor e Forma:White To Off-White SolidPeso molecular:407.04Fumagilin-105
CAS:Fumagilin-105, an autophagy-targeting chimera (AUTOTAC), induces self-oligomerization of p62 and exhibits a DC50 of 0.7 μM against MetAP2 in HEK293 cells.
Fórmula:C46H60N2O9Cor e Forma:SolidPeso molecular:784.98SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Fórmula:C22H26N4O5Cor e Forma:SolidPeso molecular:426.47
