Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1489 produtos de "Autofagia"
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TSPO Ligand-Linker Conjugates 1
TSPO Ligand-Linker Conjugates 1: a compound linking TSPO ligands to AUTACs for targeted mitophagy, aiding research in mitochondrial diseases.Fórmula:C32H55N3O10SCor e Forma:SolidPeso molecular:673.86Dusquetide TFA
Dusquetide TFA (SGX942) is an IDR that modulates immunity by targeting p62, reducing inflammation, and enhancing bacterial clearance.Fórmula:C27H48F3N9O7Cor e Forma:SolidPeso molecular:667.72Acridine homodimer
CAS:Acridine homodimer (NSC 219743), a blue-green fluorescent dye, binds DNA, preferring AT-rich areas, useful for chromosome banding.Fórmula:C38H42Cl2N6O2Cor e Forma:SolidPeso molecular:685.69Fe-TMPyP
CAS:Fe-TMPyP binds to the prion protein PrP and inhibits misfolding. Fe-TMPyP is also a peroxynitrite decomposition catalyst.Fórmula:C44H36Cl5FeN8Cor e Forma:SolidPeso molecular:909.92H1k
<p>H1k is an eudistomin Y fluorescent derivative and lysosome-targeted antiproliferative agent that downregulates the expression of cell cycle protein B1.</p>Fórmula:C27H22N2OPureza:98.13%Cor e Forma:SoildPeso molecular:390.48Autocamtide 2
CAS:<p>Autocamtide-2: Selective peptide for CaMKII, a CAMK Ser/Thr kinase.</p>Fórmula:C65H118N22O20Pureza:98%Cor e Forma:White PowderPeso molecular:1527.77Cy3-dCTP
Cy3-dCTP, a fluorescent cyanine-dye-labeled nucleotide triphosphate, serves as a DNA imaging probe.Fórmula:C43H51Li4N6O20P3S2Cor e Forma:SolidPeso molecular:1156.71Manzamine A hydrochloride
CAS:Manzamine A hydrochloride: oral beta-carboline inhibiting GSK-3β & CDK-5; blocks autophagy in cancer; antimalarial; fights HSV-1.Fórmula:C36H45ClN4OCor e Forma:SolidPeso molecular:585.23ALX 40-4C
CAS:ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.Fórmula:C56H113N37O10Pureza:98%Cor e Forma:SolidPeso molecular:1464.74Autocamtide 2, amide
Autocamtide-2, an amide, is a selective CaMKII substrate for CAMK family assays at 100 μM.Fórmula:C65H119N23O19Pureza:98%Cor e Forma:SolidPeso molecular:1526.79Polyphyllin G
CAS:Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Fórmula:C51H84O22Pureza:98%Cor e Forma:SolidPeso molecular:1049.21Cyanine 5 Tyramide methyl indole
Cyanine 5 Tyramide is a red dye used in HRP assays and nucleic acid hybridization. Store away from light.Fórmula:C40H47N3O8S2Cor e Forma:SolidPeso molecular:761.95HuMax-IL8
HuMax-IL8 (MDX 018) is a humanized anti-IL-8 monoclonal antibody for the study of metastatic or unresectable solid tumors.Pureza:98.8% (SDS-PAGE); 97.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:Odour LiquidCTCE-9908
CAS:CXCR4 blocker; triggers cell division failure in ovarian cancer, boosts taxol and docetaxel treatment effects, proven in mice.Fórmula:C86H147N27O23Pureza:98%Cor e Forma:SolidPeso molecular:1927.27CXCR4 antagonist 1
CAS:CXCR4 antagonist 1 is a potent inhibitor of the CXCR4 receptor, with notable anti-HIV activity.Fórmula:C27H43N7Cor e Forma:SolidPeso molecular:465.69DMTr-4'-CF3-5-Me-U-CED phosphoramidite
DMTr-4'-CF3-5-Me-U-CED is a dye for oligonucleotide labeling in RNA research.Fórmula:C42H50F3N4O8PCor e Forma:SolidPeso molecular:826.84MeCY5-NHS ester triethylamine
MeCY5-NHS ester (potassium) is a reactive dye optimized for labeling proteins and nucleic acids [1].Fórmula:C42H56N4O10S2Cor e Forma:SolidPeso molecular:841.04(3R,5S)-Fluvastatin
CAS:(3R,5S)-Fluvastatin, a synthetic HMG-CoA reductase inhibitor (IC50: 8 nM), activates Nrf2 for antioxidant defense.Fórmula:C24H26FNO4Cor e Forma:SolidPeso molecular:411.47KRH-3955 hydrochloride
CAS:KRH-3955 hydrochloride is an orally available CXCR4 blocker with IC50 of 0.61 nM and EC50 of 0.3-1.0 nM against X4 HIV-1.Fórmula:C28H48Cl3N7Cor e Forma:SolidPeso molecular:589.09PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withCor e Forma:Odour SolidRef: TM-L1300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultar
