Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1488 produtos de "Autofagia"
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Clematichinenoside AR
CAS:Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.Fórmula:C82H134O43Pureza:99.04% - 99.69%Cor e Forma:SolidPeso molecular:1807.92Tanespimycin
CAS:Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Fórmula:C31H43N3O8Pureza:98.24% - 99.83%Cor e Forma:Dark Purple SolidPeso molecular:585.69TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Cor e Forma:White Solid PowderPeso molecular:166.22Selenomethionine
CAS:DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.Fórmula:C5H11NO2SePureza:98% - 99.95%Cor e Forma:Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidPeso molecular:196.11Dimethyl fumarate
CAS:Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.Fórmula:C6H8O4Pureza:90.51% - >99.99%Cor e Forma:White To Off-White Powder White Crystalline PowderPeso molecular:144.13JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Fórmula:C25H27Cl2N3OCor e Forma:SolidPeso molecular:456.41Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Cor e Forma:SolidPeso molecular:1031.18GNE0877
CAS:GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).Fórmula:C14H16F3N7Pureza:98.01% - 99.97%Cor e Forma:SolidPeso molecular:339.32Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFórmula:C14H11ClN6O3Pureza:99.25% - 99.41%Cor e Forma:SolidPeso molecular:346.73STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Fórmula:C19H10N2O3Pureza:97.14% - 98.8%Cor e Forma:SolidPeso molecular:314.29Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Fórmula:C22H28N2O4Pureza:96.83% - 99.93%Cor e Forma:SolidPeso molecular:384.47ABT-751
CAS:ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Cor e Forma:SolidPeso molecular:371.41UBCS039
CAS:UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)Fórmula:C16H13N3Pureza:98.31%Cor e Forma:SolidPeso molecular:247.29CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Fórmula:C22H18Cl2N8Pureza:97.94% - ≥95%Cor e Forma:SolidPeso molecular:465.34Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39Bergapten
CAS:Bergapten (5-Methoxypsoralen), a psoralen, inhibits cell replication.Fórmula:C12H8O4Pureza:99.48% - ≥95%Cor e Forma:Needles From Alcohol; Soln In Sulfuric Acid Is Yellow-Gold Physical Description Grayish-White Micr°Crystalline Powder Or Yellow Fluffy Solid (Ntp 1992)Peso molecular:216.19Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Cor e Forma:White SolidPeso molecular:327.83IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Fórmula:C22H15Br2N3O4Pureza:98.92% - ≥95%Cor e Forma:SolidPeso molecular:545.18Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Fórmula:C15H12O4Pureza:99.61% - >99.99%Cor e Forma:SolidPeso molecular:256.25MW-150 dihydrochloride dihydrate
CAS:MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.Fórmula:C24H29Cl2N5O2Cor e Forma:SolidPeso molecular:490.43
