Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1428 produtos de "Autofagia"
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BGT226 maleate
CAS:<p>BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .</p>Fórmula:C28H25F3N6O2·C4H4O4Pureza:97.75% - 98.78%Cor e Forma:SolidPeso molecular:650.6Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Fórmula:C33H35FN2O5Pureza:99.37% - 99.69%Cor e Forma:SolidPeso molecular:558.64Dehydrocorydaline nitrate
CAS:<p>DHC curbs antibody and cell-mediated allergies, inhibits mitochondrial potential in macrophages, and has antinociceptive, anti-inflammatory effects.</p>Fórmula:C22H24N2O7Pureza:99.79% - 99.92%Cor e Forma:SolidPeso molecular:428.44VX-702
CAS:<p>VX-702: selective p38α MAPK inhibitor, potent anti-cytokine for rheumatoid arthritis.</p>Fórmula:C19H12F4N4O2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:404.32Metyrapone Tartrate
CAS:<p>Metyrapone Tartrate: a test inhibitor for diagnosing Cushing's; blocks steroid 11-beta-hydroxylase.</p>Fórmula:C22H26N2O13Cor e Forma:SolidPeso molecular:526.45Euchrysine 3RX
CAS:<p>Euchrysine 3RX is an agent of bioactive chemicals.</p>Fórmula:C20H26BrCl2N3OPureza:98%Cor e Forma:Brown PowderPeso molecular:475.25Chloroquine dihydrochloride
CAS:<p>Chloroquine: treats malaria, amebiasis, rheumatoid arthritis, lupus; works by inhibiting parasites in red blood cells.</p>Fórmula:C18H27Cl2N3Cor e Forma:SolidPeso molecular:356.33Pravastatin
CAS:<p>Pravastatin reduces lipoproteins by blocking HMG-CoA reductase and VLDL synthesis.</p>Fórmula:C23H36O7Pureza:98%Cor e Forma:White PowderPeso molecular:424.53Rac-Efavirenz
CAS:<p>Rac-Efavirenz is a non stereospecific structure of Efavirenz.</p>Fórmula:C14H9ClF3NO2Cor e Forma:SolidPeso molecular:315.67PBA-1105
CAS:<p>PBA-1105, an autophagy-targeting chimeric molecule (AUTOTAC), facilitates the self-oligomerization of p62. Additionally, PBA-1105 enhances the autophagic flux of Ub-conjugated aggregates.</p>Fórmula:C39H48N2O6Cor e Forma:SolidPeso molecular:640.81Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Cor e Forma:White SolidPeso molecular:331.15Resveratrol analog 2
CAS:<p>Resveratrol analog 2 mimics Resveratrol, a natural antioxidant with anti-inflammatory, cardioprotective, and anticancer benefits.</p>Fórmula:C16H13FO3Pureza:98%Cor e Forma:SolidPeso molecular:272.27TAMRA alkyne, 6-isomer
CAS:<p>TAMRA alkyne, 6-isomer: a xanthene dye linker with orange emission, used for DNA/RNA labeling, reacts via Click Chemistry.</p>Fórmula:C28H25N3O4Cor e Forma:SolidPeso molecular:467.52Seriniquinone
CAS:<p>Seriniquinone is a selective agent of anticancer that acts by inducing cell death via autophagocytosis and targeting the cancer-protective protein dermcidin.</p>Fórmula:C20H8O4SPureza:98%Cor e Forma:SolidPeso molecular:344.34YT-8-8
CAS:<p>YT-8-8 is a ligand for the p62-ZZ domain and can activate p62-dependent selective autophagy. This compound is also applicable in AUTOTAC design.</p>Fórmula:C18H23FN2O2Cor e Forma:SolidPeso molecular:318.39Gavilimomab
CAS:<p>Gavilimomab(ABX-CBL) is a murine-derived IgM monoclonal antibody against CD147 antigen used in immunosuppressive treatments for glucocorticoid-resistant GVHD).</p>Pureza:95%Cor e Forma:LiquidErlotinib mesylate
CAS:<p>Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.</p>Fórmula:C23H27N3O7SPureza:98%Cor e Forma:SolidPeso molecular:489.54Paroxetine hydrochloride hemihydrate
CAS:<p>Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).</p>Fórmula:C38H44Cl2F2N2O7Pureza:99.949%Cor e Forma:SolidPeso molecular:749.67SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Cor e Forma:Orange PowderPeso molecular:568.09Antitumor agent-81
CAS:<p>Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.</p>Fórmula:C19H19N7O3Cor e Forma:SolidPeso molecular:393.4
