Receptor de Bombesina
Os receptores de bombesina são um grupo de GPCRs ativados por peptídeos semelhantes à bombesina, que estão envolvidos na regulação da função gastrointestinal, do equilíbrio energético e da proliferação celular. Esses receptores são de particular interesse na pesquisa do câncer, pois são frequentemente superexpressos em certos tipos de tumores. Antagonistas de receptores de bombesina são estudados por seu potencial como terapêuticos contra o câncer. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de bombesina de alta qualidade para apoiar sua pesquisa em oncologia, fisiologia gastrointestinal e sinalização de receptores.
Foram encontrados 30 produtos de "Receptor de Bombesina"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
CD80-IN-3
CAS:<p>CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).</p>Fórmula:C17H10FN3O3Pureza:98.08%Cor e Forma:SolidPeso molecular:323.28AMTG-DA1
<p>AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.</p>Fórmula:C101H149IN22O25Cor e Forma:SolidPeso molecular:2197.0109RC-3095
CAS:<p>RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.</p>Fórmula:C56H79N15O9Pureza:98%Cor e Forma:SolidPeso molecular:1106.32BA 1
CAS:<p>Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.</p>Fórmula:C57H76N14O11Pureza:98%Cor e Forma:SolidPeso molecular:1133.32PSMA/GRPR ligand 1
<p>PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).</p>Cor e Forma:Odour Solid[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:<p>Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.</p>Fórmula:C79H109N19O12Pureza:98%Cor e Forma:SolidPeso molecular:1516.85[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Fórmula:C74H112N22O18SPureza:98%Cor e Forma:SolidPeso molecular:1629.88[D-Phe12,Leu14]-Bombesin
CAS:<p>Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.</p>Fórmula:C77H113F3N22O20Pureza:98%Cor e Forma:SolidPeso molecular:1724.9(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:<p>(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].</p>Fórmula:C49H69N13O9Cor e Forma:SolidPeso molecular:984.15BA 1 TFA
<p>BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.</p>Fórmula:C59H77F3N14O13Cor e Forma:SolidPeso molecular:1247.32Ici 216140
CAS:<p>ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.</p>Fórmula:C45H65N13O8Cor e Forma:SolidPeso molecular:916.08GRP (14-27) (human, porcine, canine)
CAS:<p>GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not</p>Fórmula:C75H110N24O16S2Pureza:98%Cor e Forma:SolidPeso molecular:1667.96GB-6
CAS:<p>GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due to</p>Fórmula:C32H45N11O8Pureza:98%Cor e Forma:SolidPeso molecular:711.77RC-3095 TFA
CAS:<p>RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.</p>Fórmula:C58H80F3N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1220.34Bombesin
CAS:<p>Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.</p>Fórmula:C71H110N24O18SCor e Forma:While Lyophilized PowderPeso molecular:1619.85PD176252
CAS:<p>PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.</p>Fórmula:C32H36N6O5Pureza:99.18%Cor e Forma:SolidPeso molecular:584.67ML-18
CAS:<p>ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.</p>Fórmula:C32H35N5O5Pureza:98.62% - >99.99%Cor e Forma:SolidPeso molecular:569.65kuwanon G
CAS:<p>Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.</p>Fórmula:C40H36O11Pureza:98% - 99.57%Cor e Forma:SolidPeso molecular:692.71Litorin acetate(55749-97-8 Free base)
<p>Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.</p>Fórmula:C53H72N14O13SPureza:98.61%Cor e Forma:SolidPeso molecular:1145.29Bombesin acetate(31362-50-2 free base)
CAS:<p>Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).</p>Fórmula:C73H114N24O20SPureza:98.44%Cor e Forma:SolidPeso molecular:1679.92
![[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1931.webp&w=3840&q=75)
![[D-Phe12]-Bombesin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2239.webp&w=3840&q=75)
![[D-Phe12,Leu14]-Bombesin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1916.webp&w=3840&q=75)
