Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 326 produtos de "Receptor opioide"
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JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Fórmula:C28H41Cl2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:538.55Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Fórmula:C16H20N2O5Cor e Forma:SolidPeso molecular:320.34BNTX
CAS:BNTX (7-Benzylidenenaltrexone) is a selective δ1-opioid receptor antagonist. It competitively counteracts the antisecretory effects of DPDPE, Deltorphin 2, and DAMGO. BNTX is applicable in research focused on antinociceptive effects.Fórmula:C27H27NO4Cor e Forma:SolidPeso molecular:429.508Riminkefon
CAS:Riminkefon is a kappa opioid receptor agonist .Fórmula:C38H57N7O6Cor e Forma:SolidPeso molecular:707.9rel-SB-612111 hydrochloride
CAS:NOP receptor antagonistFórmula:C24H30Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:454.86BU72
CAS:BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.Fórmula:C28H32N2O2Cor e Forma:SolidPeso molecular:428.57Naldemedine tosylate
CAS:Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.Fórmula:C39H42N4O9SCor e Forma:SolidPeso molecular:742.84Anilopam
CAS:Anilopam is an opioid analgesic belonging to the benzazepine class and acts as an agonist at opioid receptors.Fórmula:C20H26N2OCor e Forma:SolidPeso molecular:310.4322-Thiocyanatosalvinorin A
CAS:22-Thiocyanatosalvinorin A (RB-64) is a potent selective agonist for the kappa-opioid receptor, exhibiting an EC50 value of 0.077 nM.Fórmula:C24H27NO8SCor e Forma:SolidPeso molecular:489.54(S)-MCOPPB
CAS:(S)-MCOPPB is the S-enantiomer of MCOPPB, an orally active selective agonist for the Nociceptin/Orphanin FQ-Receptor. It inhibits signal transduction in mouse brain NOP receptors and is utilized in anxiety disorder research.Fórmula:C26H40N4Cor e Forma:SolidPeso molecular:408.623Phenethyl 4-ANPP
CAS:Phenethyl 4-ANPP is a MOR (μ-opioid receptor) agonist with a structure similar to known opioids.Fórmula:C27H32N2Cor e Forma:SolidPeso molecular:384.56Mu opioid receptor antagonist 4
Compound 31: Potent, selective MOR antagonist; crosses blood-brain barrier; Ki & EC50: 0.38 nM; useful for OUD research.Fórmula:C25H28N2O4SCor e Forma:SolidPeso molecular:452.57KNT-127
CAS:KNT-127 is an agonist of δ-Opioid receptor.Fórmula:C24H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:372.46(±)-J 113397
CAS:(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Fórmula:C24H37N3O2Cor e Forma:SolidPeso molecular:399.575′-Guanidinonaltrindole
CAS:5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.Fórmula:C27H29N5O3Cor e Forma:SolidPeso molecular:471.551Bromadoline
CAS:Bromadoline is an opioid compound that exhibits anti-nociceptive properties in rodents.Fórmula:C15H21BrN2OCor e Forma:SolidPeso molecular:325.244Mu opioid receptor antagonist 5
Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53DS34942424
DS34942424 is an orally potent analgesic which did not exhibit mu opioid receptor agonist activity.Fórmula:C15H17FN2OCor e Forma:SolidPeso molecular:260.31NOP agonist-1
CAS:NOP agonist-1 (compound 4) is a nociceptin opioid receptor (NOP) partial agonist that attenuates Parkinsonian disabilities in 6-OHDA hemilesioned rats [1].Fórmula:C22H34N2Peso molecular:326.52Salvinorin A Propionate
CAS:Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.Fórmula:C24H30O8Cor e Forma:SolidPeso molecular:446.49
