Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 332 produtos para "Receptor opioide".
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ADL-08-0011
CAS:ADL-08-0011 is an metabolite of alvimopan.Fórmula:C23H29NO3Cor e Forma:SolidPeso molecular:367.49Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Fórmula:C26H31N3OPureza:98%Cor e Forma:SolidPeso molecular:401.54(S)-MCOPPB
CAS:(S)-MCOPPB is the S-enantiomer of MCOPPB, an orally active selective agonist for the Nociceptin/Orphanin FQ-Receptor. It inhibits signal transduction in mouse brain NOP receptors and is utilized in anxiety disorder research.Fórmula:C26H40N4Cor e Forma:SolidPeso molecular:408.623Opioid receptor antagonist 1
CAS:Opioid receptor antagonist 1 (Compound 10) is an Orvinol-based antagonist of opioid receptors. It exhibits activity as an antagonist against the analgesic properties of morphine.Fórmula:C24H29ClF3NO4Cor e Forma:SolidPeso molecular:487.94Naltrindole 5′-isothiocyanate
CAS:Naltrindole 5′-isothiocyanate (5'-NTII) is an irreversible delta opioid receptor antagonist that counters the analgesic effects induced by DSLET without altering the effects caused by DPDPE.Fórmula:C27H25N3O3SCor e Forma:SolidPeso molecular:471.571Bromadoline
CAS:Bromadoline is an opioid compound that exhibits anti-nociceptive properties in rodents.Fórmula:C15H21BrN2OCor e Forma:SolidPeso molecular:325.244KNT-127
CAS:KNT-127 is an agonist of δ-Opioid receptor.Fórmula:C24H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:372.46(±)-J 113397
CAS:(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).Fórmula:C24H37N3O2Cor e Forma:SolidPeso molecular:399.575′-Guanidinonaltrindole
CAS:5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.Fórmula:C27H29N5O3Cor e Forma:SolidPeso molecular:471.551GNTI dihydrochloride
CAS:κ opioid receptor antagonistFórmula:C27H30ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:508.01J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Fórmula:C24H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:399.57BNTX
CAS:BNTX (7-Benzylidenenaltrexone) is a selective δ1-opioid receptor antagonist. It competitively counteracts the antisecretory effects of DPDPE, Deltorphin 2, and DAMGO. BNTX is applicable in research focused on antinociceptive effects.Fórmula:C27H27NO4Cor e Forma:SolidPeso molecular:429.508Phenethyl 4-ANPP
CAS:Phenethyl 4-ANPP is a MOR (μ-opioid receptor) agonist with a structure similar to known opioids.Fórmula:C27H32N2Cor e Forma:SolidPeso molecular:384.56Volazocine
CAS:Volazocine is a potent orally active agonist with anesthetic-antagonistic properties. It can be synthesized via two independent pathways: one involves nitration followed by reduction of volazocine, and the other utilizes dissolving metal reduction of cyclazocine methyl ether, followed by oximation and the Semmler-Wolff rearrangement sequence. Several analogs have also been prepared and tested in studies.Fórmula:C18H25NPeso molecular:255.40[Dmt1]DALDA
CAS:[Dmt1]DALDA is a potent and long-lasting analgesic that interacts with the μ-opioid receptor (mu-opioid receptor), exhibiting high affinity and selectivity. It acts as a full agonist for hMOR (Kd= 0.199 nM) and hDOR, yet only serves as a partial agonist for hKOR.Fórmula:C32H49N9O5Peso molecular:639.79DPI-3290
CAS:DPI-3290 is a specific agonist of opioid receptors (Ki: 0.18 nM, 0.46 nM, and 0.62 nM for δ-, μ-, and κ-opioid receptors, respectively) with potentFórmula:C30H34FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:487.61MTI013
MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.Fórmula:C24H26N6O4SCor e Forma:SolidPeso molecular:494.57NOP agonist-1
CAS:NOP agonist-1 (compound 4) is a nociceptin opioid receptor (NOP) partial agonist that attenuates Parkinsonian disabilities in 6-OHDA hemilesioned rats [1].Fórmula:C22H34N2Cor e Forma:SolidPeso molecular:326.52Sameridine hydrochloride
CAS:Sameridine hydrochloride, a local anesthetic and local analgesic [1].Fórmula:C21H35ClN2OPeso molecular:366.97Salvinorin A Propionate
CAS:Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.Fórmula:C24H30O8Cor e Forma:SolidPeso molecular:446.49
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