Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 327 produtos de "Receptor opioide"
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Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Fórmula:C90H132N26O25Pureza:98%Cor e Forma:SolidPeso molecular:1978.17Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Cor e Forma:Odour SolidRo 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Fórmula:C26H31N3OPureza:98%Cor e Forma:SolidPeso molecular:401.54Axelopran
CAS:Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.Fórmula:C26H39N3O4Cor e Forma:SolidPeso molecular:457.61Biphalin TFA
CAS:Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores.Fórmula:C46H56N10O10·xC2HF3O2Pureza:98%Cor e Forma:SolidPeso molecular:909.00 (free base)β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Fórmula:C156H249F3N42O46SCor e Forma:SolidPeso molecular:3537.96Frakefamide TFA
Frakefamide TFA: potent, peripherally active μ-opioid agonist; doesn't cross blood-brain barrier.Fórmula:C32H35F4N5O7Cor e Forma:SolidPeso molecular:677.64DPDPE
CAS:DPDPE is selective δ-opioid receptor agonist peptide.Fórmula:C30H39N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:645.79[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Fórmula:C65H107N21O15Pureza:99.59%Cor e Forma:SoildPeso molecular:1422.7DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Fórmula:C28H36F3N5O8Pureza:98%Cor e Forma:SolidPeso molecular:627.61Orphanin FQ(1-11)
CAS:Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.Fórmula:C49H75N15O14Pureza:98%Cor e Forma:SolidPeso molecular:1098.2HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Fórmula:C23H24N8O5Cor e Forma:SolidPeso molecular:492.49KOR agonist 4
KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.Fórmula:C21H25N3Cor e Forma:SolidPeso molecular:319.44Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Fórmula:C44H59N11O10Pureza:98%Cor e Forma:SolidPeso molecular:901.43[Nphe1]Nociceptin(1-13)NH2
CAS:Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.Fórmula:C61H100N22O15Pureza:98%Cor e Forma:SolidPeso molecular:1381.6ICI 174,864
CAS:Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.Fórmula:C38H53N5O7Pureza:98%Cor e Forma:White SolidPeso molecular:691.87UFP-101
CAS:Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.
Fórmula:C82H138N32O21Pureza:98%Cor e Forma:SolidPeso molecular:1908.19Dermorphin
CAS:Dermorphin is agonist of μ-opioid receptor (MOR) agonist.Fórmula:C40H50N8O10Pureza:98.82%Cor e Forma:SolidPeso molecular:802.87Akuammicine
CAS:Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.Fórmula:C20H22N2O2Cor e Forma:SolidPeso molecular:322.408Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Fórmula:C44H70N14O9Pureza:98%Cor e Forma:SolidPeso molecular:939.12
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