SGLT
Os co-transportadores sódio-glicose (SGLT) são proteínas de membrana que facilitam a reabsorção de glicose nos rins ao acoplar o transporte de glicose aos íons de sódio. Inibidores de SGLT são uma classe importante de medicamentos usados no tratamento do diabetes tipo 2, pois ajudam a reduzir os níveis de glicose no sangue ao prevenir a reabsorção de glicose nos túbulos renais. Esses inibidores também estão sendo investigados por seus potenciais benefícios na proteção cardiovascular e renal. Na CymitQuimica, oferecemos uma gama de moduladores de SGLT de alta qualidade para apoiar sua pesquisa em diabetes, fisiologia renal e distúrbios metabólicos.
Foram encontrados 31 produtos de "SGLT"
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KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Fórmula:C26H40N4O8Pureza:98.46%Cor e Forma:SolidPeso molecular:536.62Ref: TM-T15656
1mg109,00€2mg158,00€5mg260,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)305,00€Sergliflozin A
CAS:Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Fórmula:C20H24O7Pureza:99.71%Cor e Forma:SolidPeso molecular:376.4O-Desethyl Dapagliflozin
CAS:O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Fórmula:C19H21ClO6Pureza:98.33%Cor e Forma:SolidPeso molecular:380.82Ref: TM-T67849
1mg57,00€5mg120,00€10mg187,00€25mg321,00€50mg470,00€100mg683,00€1mL*10mM (DMSO)135,00€Canagliflozin (Standard)
CAS:Canagliflozin (Standard) is the standard substance of Canagliflozin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM).Fórmula:C24H25FO5SCor e Forma:SolidPeso molecular:444.52Sotagliflozin
CAS:Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFórmula:C21H25ClO5SPureza:99% - 99.86%Cor e Forma:SolidPeso molecular:424.94Ref: TM-T3547
1mg46,00€2mg57,00€5mg87,00€10mg131,00€25mg248,00€50mg378,00€100mg560,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Empagliflozin
CAS:Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6.Fórmula:C23H27ClO7Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:450.91Ref: TM-T1766
1g278,00€5mg47,00€10mg60,00€50mg79,00€100mg96,00€200mg144,00€500mg188,00€1mL*10mM (DMSO)50,00€Mizagliflozin
CAS:Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Fórmula:C28H44N4O8Pureza:98.66% - 99.67%Cor e Forma:SolidPeso molecular:564.67Ref: TM-T16083
1mg66,00€2mg96,00€5mg144,00€10mg227,00€25mg455,00€50mg645,00€100mg938,00€200mg1.264,00€1mL*10mM (DMSO)173,00€Dapagliflozin
CAS:Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.Fórmula:C21H25ClO6Pureza:99.5% - 99.93%Cor e Forma:SolidPeso molecular:408.87Ref: TM-T2389
5mg47,00€10mg60,00€25mg77,00€50mg94,00€100mg107,00€200mg142,00€1500mg284,00€1mL*10mM (DMSO)52,00€Enavogliflozin
CAS:Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Fórmula:C24H27ClO6Pureza:97.37%Cor e Forma:SolidPeso molecular:446.92Ref: TM-T38843
1mg156,00€5mg378,00€10mg590,00€25mg1.026,00€50mg1.406,00€100mg1.863,00€1mL*10mM (DMSO)415,00€Ipragliflozin
CAS:Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
Fórmula:C21H21FO5SPureza:99.38% - 99.70%Cor e Forma:SolidPeso molecular:404.45T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Fórmula:C26H28O11Pureza:99.78%Cor e Forma:SolidPeso molecular:516.49Ref: TM-T9590
1mg50,00€2mg71,00€5mg90,00€10mg130,00€25mg207,00€50mg370,00€100mg530,00€1mL*10mM (DMSO)127,00€Phloretin
CAS:Phloretin (NSC-407292) inhibits eukaryotic urea transporters, has antioxidative properties, and can induce cancer cell apoptosis. Found in apples and apricots.
Fórmula:C15H14O5Pureza:98.53% - >99.99%Cor e Forma:SolidPeso molecular:274.27Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Fórmula:C24H35ClO9Pureza:99.88% - 99.94%Cor e Forma:SolidPeso molecular:502.98Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Fórmula:C24H25FO5SPureza:98.01% - >99.99%Cor e Forma:SolidPeso molecular:444.52Ref: TM-T1782
2mg35,00€5mg50,00€10mg66,00€25mg87,00€50mg96,00€100mg123,00€500mg274,00€1mL*10mM (DMSO)52,00€Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
Fórmula:C21H24O10Pureza:99.73% - 99.77%Cor e Forma:Solid CrystallinePeso molecular:436.41Tofogliflozin (hydrate)
CAS:Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Fórmula:C22H28O7Pureza:97.03% - 98.78%Cor e Forma:SolidPeso molecular:404.45Ref: TM-T5016
1mg38,00€2mg52,00€5mg79,00€10mg115,00€25mg213,00€50mg341,00€100mg533,00€200mg757,00€1mL*10mM (DMSO)87,00€Ertugliflozin
CAS:PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).Fórmula:C22H25ClO7Pureza:99.89% - 99.96%Cor e Forma:SolidPeso molecular:436.88Bexagliflozin
CAS:Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Fórmula:C24H29ClO7Pureza:98.99% - 99.89%Cor e Forma:SolidPeso molecular:464.94Ref: TM-T7217
1mg67,00€2mg95,00€5mg129,00€10mg187,00€25mg371,00€50mg552,00€100mg785,00€1mL*10mM (DMSO)137,00€Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Cor e Forma:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)109,00€Canagliflozin hemihydrate
CAS:Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Fórmula:C48H52F2O11S2Pureza:99.42% - 99.96%Cor e Forma:SolidPeso molecular:907.05Dapagliflozin-d5
CAS:Dapagliflozin D5 (BMS-512148 D5) is deuterated Dapagliflozin. Dapagliflozin is a competitive SGLT2 inhibitor.Fórmula:C21H25ClO6Pureza:98%Cor e Forma:SolidPeso molecular:413.9Licogliflozin
CAS:Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Fórmula:C23H28O7Pureza:98%Cor e Forma:SolidPeso molecular:416.46HSK0935
CAS:HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities.Fórmula:C22H25ClO7Pureza:98%Cor e Forma:SolidPeso molecular:436.88Sergliflozin etabonate
CAS:Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.Fórmula:C23H28O9Pureza:97.88%Cor e Forma:SolidPeso molecular:448.46Ref: TM-T28757
1mg87,00€5mg215,00€10mg321,00€25mg518,00€50mg692,00€100mg944,00€1mL*10mM (DMSO)212,00€Remogliflozin etabonate
CAS:Remogliflozin etabonate is a prodrug SGLT2 inhibitor; Ki for hSGLT2: 1.95μM, rSGLT2: 2.14μM, rSGLT1: 8.57μM, hSGLT1: 43.1μM.Fórmula:C26H38N2O9Pureza:98.98%Cor e Forma:SolidPeso molecular:522.59Ref: TM-T34286
2mg34,00€5mg50,00€10mg92,00€25mg156,00€50mg231,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)58,00€Velagliflozin
CAS:Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2.Fórmula:C23H25NO5Pureza:98%Cor e Forma:SolidPeso molecular:395.45Ertugliflozin L-pyroglutamic acid
CAS:Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.Fórmula:C27H32ClNO10Pureza:99.88% - 99.94%Cor e Forma:SolidPeso molecular:566Ref: TM-T15244
5mg47,00€10mg60,00€25mg89,00€50mg96,00€100mg140,00€200mg198,00€500mg340,00€1mL*10mM (DMSO)52,00€SGLT1/2-IN-8
CAS:SGLT1/2-IN-8 (compound 8) is a potent and orally active dual inhibitor of SGLT1/2, exhibiting IC50 values of 4 nM and 1 nM, respectively. It shows antihyperglycemic properties, making it suitable for related research.Fórmula:C22H26O6Cor e Forma:SolidPeso molecular:386.438SGLT inhibitor-1
CAS:SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).Fórmula:C24H27FO8Pureza:98%Cor e Forma:SolidPeso molecular:462.46SGL5213
CAS:SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Fórmula:C37H55N3O8Pureza:98%Cor e Forma:SolidPeso molecular:669.85Canagliflozin-d4
CAS:Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.
Fórmula:C24H25FO5SPureza:98%Cor e Forma:SolidPeso molecular:448.54Ref: TM-T10669
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