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Receptor Glucagon

Receptor Glucagon

Os receptores de glucagon são GPCRs que mediam os efeitos do glucagon, um hormônio envolvido na regulação da homeostase da glicose, promovendo a quebra de glicogênio e a liberação de glicose pelo fígado. Esses receptores são críticos na gestão dos níveis de açúcar no sangue e são de particular interesse no estudo do diabetes e distúrbios metabólicos. Antagonistas dos receptores de glucagon estão sendo explorados como potenciais tratamentos para hiperglicemia no diabetes tipo 2. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores de glucagon de alta qualidade para apoiar sua pesquisa em endocrinologia, diabetes e regulação metabólica.

Foram encontrados 164 produtos de "Receptor Glucagon"

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  • Crotedumab

    CAS:
    <p>Crotedumab (REGN1193) is a humanized antibody targeting GCGR, which reduces fasting blood glucose and improves glucose tolerance, used in diabetes research.</p>
    Pureza:>95%
    Cor e Forma:Liquid
  • Volagidemab

    CAS:
    <p>Anti-CD34 Antibody is a CHO-expressed humanized monoclonal antibody targeting CD34, which can be used for the study of neurological and cardiovascular diseases.</p>
    Pureza:97.8% (SDS-PAGE); 98% (SEC-HPLC) - 97.8% (SDS-PAGE); 98% (SEC-HPLC)
    Cor e Forma:Liquid
  • Glucagon (1-29), bovine, human, porcine hydrochloride

    CAS:
    <p>Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon increases HNF4α phosphorylation.</p>
    Fórmula:C153H225N43O49S·ClH
    Pureza:95.65% - 98.03%
    Cor e Forma:Solid
    Peso molecular:3519.21
  • Retatrutide sodium salt


    <p>Retatrutide sodium salt is a glucagon receptor and glucagon-like peptide-1 receptor agonist for the study of type 2 diabetes mellitus.</p>
    Pureza:99.97%
    Cor e Forma:Soild
  • PF-06882961

    CAS:
    <p>PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Fórmula:C31H30FN5O4
    Pureza:98.06% - 99.54%
    Cor e Forma:Solid
    Peso molecular:555.6
  • Tirzepatide monosodium salt


    <p>Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.</p>
    Fórmula:C225H347N48O68Na
    Pureza:99.69%
    Cor e Forma:Soild
    Peso molecular:4835.51
  • Retatrutide

    CAS:
    <p>Retatrutide (LY3437943) is a triple agonist of GCGR, GIPR and GLP-1R that can be used to study obesity.</p>
    Fórmula:C221H342N46O68
    Pureza:98.31%
    Cor e Forma:Solid
    Peso molecular:4732.09
  • Avexitide acetate

    CAS:
    <p>Avexitide acetate (exendin 9-39) is a potent glucagon-like peptide 1 receptor (GLP-1R) antagonist for the study of post-obesity hypoglycemia.</p>
    Fórmula:C155H246N40O53S
    Pureza:96.64% - 98.65%
    Cor e Forma:Solid
    Peso molecular:3549.91
  • (S, R)-LSN 3318839

    CAS:
    <p>(S,R)-LSN 3318839 enhances GLP-1R, shows strong blood sugar lowering in animals, works with sitagliptin.</p>
    Fórmula:C26H23Cl2N3O2
    Pureza:99.57%
    Cor e Forma:Soild
    Peso molecular:480.39
  • GLP-1R Agonist DMB

    CAS:
    <p>GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).</p>
    Fórmula:C13H15Cl2N3O2S
    Pureza:99.52%
    Cor e Forma:Solid
    Peso molecular:348.25
  • GLP-1R Antagonist 1

    CAS:
    <p>GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).</p>
    Fórmula:C16H11ClF6N4O2
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:440.73
  • HAEGTFTSD

    CAS:
    <p>HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.</p>
    Fórmula:C40H57N11O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:963.94
  • Tirzepatide

    CAS:
    <p>Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.</p>
    Fórmula:C225H348N48O68
    Pureza:99.52% - 99.99%
    Cor e Forma:Solid
    Peso molecular:4813.45
  • HAEGT

    CAS:
    <p>HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.</p>
    Fórmula:C20H31N7O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:513.5
  • Glucagon receptor antagonists-1

    CAS:
    <p>Glucagon receptor antagonist -1 is a highly effective glucagon receptor antagonist.</p>
    Fórmula:C29H34FNO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:447.58
  • V-0219 hydrochloride


    <p>V-0219 hydrochloride: oral GLP-1R PAM for obesity-linked diabetes study.</p>
    Fórmula:C20H26ClF3N4O2
    Pureza:99.97%
    Cor e Forma:Soild
    Peso molecular:446.89
  • Orforglipron

    CAS:
    <p>Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1</p>
    Fórmula:C48H48F2N10O5
    Pureza:99.47% - 99.8%
    Cor e Forma:Solid
    Peso molecular:882.96
  • GLP-1 moiety from Dulaglutide


    <p>GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide which is a glucagon-like peptide 1 receptor (GLP-1) agonist.</p>
    Fórmula:C149H221N37O49
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3314.62
  • HAEGTFTSD acetate(926018-45-3 free base)


    <p>HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from</p>
    Fórmula:C42H61N11O19
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1024.01
  • GLP-1 receptor agonist 13


    <p>Compound (S)-9, a GLP-1 receptor agonist, exhibits an EC50 of 76 nM for the glucagon GLP-1 receptor [1].</p>
    Fórmula:C25H23ClF2N6O
    Cor e Forma:Solid
    Peso molecular:496.94
  • Albiglutide Fragment

    CAS:
    <p>Albiglutide fragment is a 30-amino-acid sequence of modified human GLP-1 (fragment 7-36).</p>
    Fórmula:C148H224N40O45
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3283.6
  • 6α-Methylprednisolone 21-hemisuccinate sodium salt

    CAS:
    <p>6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.</p>
    Fórmula:C26H33NaO8
    Pureza:99.65%
    Cor e Forma:Lyophilized Powder
    Peso molecular:496.53
  • Cinnamtannin A2

    CAS:
    <p>Cinnamtannin A2, a tetrameric procyanidin, boosts GLP-1, insulin, CRH expression, and has antioxidant, anti-diabetic, nephroprotective properties.</p>
    Fórmula:C60H50O24
    Cor e Forma:Solid
    Peso molecular:1155.02
  • Tirzepatide hydrochloride


    <p>Tirzepatide HCl is a dual GIP and GLP-1 receptor agonist.</p>
    Fórmula:C225H349N48O68Cl
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4849.91
  • Survodutide TFA


    <p>Survodutide TFA (BI 456906 TFA) is a GCGR/GLP-1R dual agonist, a peptide compound used in obesity research.</p>
    Fórmula:C192H289N47O61·xC2HF3OC2
    Pureza:99.29% - 99.96%
    Cor e Forma:Solid
    Peso molecular:4231.62 (free base)
  • Secretin (28-54), human TFA


    <p>Secretin (28-54), human TFA is a 27-amino acid peptide that works on the human Secretin receptor.</p>
    Fórmula:C132H221N44F3O42
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3153.48
  • VU0453379

    CAS:
    <p>VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).</p>
    Fórmula:C26H34N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:434.57
  • GLP-1 receptor agonist 4

    CAS:
    <p>GLP-1 receptor agonist 4 targets GLP-1R, EC50 64.5 nM, potential diabetes treatment research.</p>
    Fórmula:C51H44Cl2N4O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:879.82
  • Glucagon (19-29), human

    CAS:
    <p>Glucagon, a 29-amino-acid hormone, is produced by alpha cells in the pancreas' islets of Langerhans.</p>
    Fórmula:C61H89N15O18S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1352.53
  • GLP-1R agonist 19

    CAS:
    <p>GLP-1R agonist 19 (M3190) is a potent, selective GLP-1 receptor agonist that demonstrates excellent plasma and liver microsomal stability, along with low hERG toxicity [1].</p>
    Fórmula:C94H136FN21O25
    Cor e Forma:Solid
    Peso molecular:1979.21
  • Peptide C105Y TFA


    <p>Peptide C105Y TFA is a cell-penetrating peptide synthesized based on the amino acid sequence of residues 359-374 of α1-antitrypsin. It enhances the gene expression of DNA nanoparticles.</p>
    Fórmula:C97H148N20O23S·xC2HF3O2
  • Orforglipron hemicalcium hydrate

    CAS:
    <p>Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) represents the hemicalcium hydrate form of the calcium salt of Orforglipron, an orally active agonist targeting the Glucagon-like peptide-1 receptor (GLP-1R). This compound has demonstrated efficacy in mitigating type 2 diabetes [1].</p>
    Fórmula:C48H48F2N10O5Ca·H2O
    Cor e Forma:Solid
    Peso molecular:921.02
  • Secretin (33-59), rat TFA


    <p>Secretin (33-59), rat (TFA), a 27-aa peptide, stimulates the secretin receptor, increasing pancreas secretion of bicarbonate, enzymes, and K+.</p>
    Fórmula:C131H217F3N42O44
    Cor e Forma:Solid
    Peso molecular:3141.37
  • Ecnoglutide

    CAS:
    <p>Ecnoglutide (XW003) is a glucagon-like peptide 1 (GLP-1) receptor agonist [1] .</p>
    Fórmula:C194H304N48O61
    Cor e Forma:Solid
    Peso molecular:4284.76
  • GLP-1R/GIPR agonist-1


    <p>GLP-1R/GIPR agonist-1 is a dual receptor agonist for GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). It mimics the action of endogenous hormones GLP-1 and GIP, enhancing insulin secretion while suppressing glucagon release, thus lowering blood sugar. This compound is used in research related to metabolic disorders such as diabetes, obesity, and non-alcoholic steatohepatitis (NASH).</p>
    Fórmula:C220H342N55O69
    Peso molecular:4858.49434
  • GLP-1 receptor agonist 9 citrate


    <p>GLP-1 receptor agonist 9 citrate is an agonist of GLP-1.</p>
    Fórmula:C38H39ClFN3O12
    Pureza:98.76%
    Cor e Forma:Solid
    Peso molecular:784.18
  • GLP-1 (9-36) amide

    CAS:
    <p>GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor.</p>
    Fórmula:C140H214N36O43
    Pureza:97%
    Cor e Forma:Solid
    Peso molecular:3089.41
  • GLP-1(28-36)amide TFA


    <p>GLP-1(28-36)amide TFA, a nonapeptide cleavage product of GLP-1, shows antioxidant properties with anti-diabetic and cardioprotective effects.</p>
    Fórmula:C56H86F3N15O11
    Cor e Forma:Solid
    Peso molecular:1202.37
  • GLP-1(9-36)amide TFA


    <p>GLP-1(9-36)amide TFA, a DPP-4 metabolite of GLP-1(7-36) amide, antagonizes human pancreatic GLP-1 receptor.</p>
    Fórmula:C142H215F3N36O45
    Cor e Forma:Solid
    Peso molecular:3203.43
  • Anti-GLP1R Antibody


    <p>Anti-GLP1R Antibody is a human antibody expressed in CHO cells, targeting GLP1R. For isotype controls, refer to Human IgG1 kappa, Isotype Control.</p>
    Cor e Forma:Odour Liquid
  • Utreglutide

    CAS:
    <p>Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit [1] .</p>
    Fórmula:C191H298N46O58
    Cor e Forma:Solid
    Peso molecular:4166.67
  • Bay 55-9837 TFA


    <p>Bay 55-9837 TFA is a VPAC2 agonist with a 0.65 nM Kd, potential for type 2 diabetes research.</p>
    Fórmula:C150H240F3ClN44O44
    Cor e Forma:Solid
    Peso molecular:3456.22
  • Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide


    <p>Biotin-labeled GLP-1-(7-36) amide; a gut peptide that enhances insulin release.</p>
    Fórmula:C165H252N44O48S
    Cor e Forma:Solid
    Peso molecular:3652.1
  • Tirzepatide TFA


    <p>Tirzepatide TFA, a GIP and GLP-1 agonist, targets type 2 diabetes treatment.</p>
    Fórmula:C227H349F3N48O70
    Cor e Forma:Solid
    Peso molecular:4927.47
  • Exendin-4 (3-39)

    CAS:
    <p>Exendin-4 (3-39) is a truncated peptide missing first 2 amino acids of Exendin-4, a potent GLP-1r agonist used in diabetes and HPA axis research.</p>
    Fórmula:C176H272N46O58S
    Cor e Forma:Solid
    Peso molecular:3992.44
  • Glucagon-like peptide 1 (1-37), human

    CAS:
    <p>Human GLP-1 (1-37) is a potent GLP-1 receptor agonist without impact on rat food intake or insulin secretion.</p>
    Fórmula:C186H275N51O59
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4169.48
  • Secretin (28-54), human

    CAS:
    <p>Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.</p>
    Fórmula:C130H220N44O40
    Pureza:98%
    Cor e Forma:Powder
    Peso molecular:3039.46
  • Albenatide

    CAS:
    <p>Albenatide is a modified analog of exendin 4 conjugated to recombinant human albumin.</p>
    Fórmula:C26H47N7O9S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:633.76
  • HAEGTFTSDVS

    CAS:
    <p>HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.</p>
    Fórmula:C48H71N13O20
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1150.18
  • Pal-Glu(OSu)-OH

    CAS:
    <p>Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.</p>
    Fórmula:C25H42N2O7
    Cor e Forma:Solid
    Peso molecular:482.618
  • TT-OAD2

    CAS:
    <p>TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.</p>
    Fórmula:C50H49Cl4N3O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:929.75
  • GLP-2(1-33)(human)

    CAS:
    <p>GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.</p>
    Fórmula:C165H254N44O55S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3766.19
  • HAEGTFT

    CAS:
    <p>HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.</p>
    Fórmula:C33H47N9O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:761.78
  • GLP-1(7-36), amide acetate

    CAS:
    <p>GLP-1(7-36), amide acetate is a derivative of GLP-1 peptide , activate the GLP-1 receptor, promote insulin secretion,Type 2 diabetes mellitus and obesity.</p>
    Fórmula:C151H230N40O47
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:3357.68
  • Apraglutide

    CAS:
    <p>Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.</p>
    Fórmula:C172H263N43O52
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3765.25
  • Dulaglutide

    CAS:
    <p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>
    Cor e Forma:Solid
  • Taspoglutide

    CAS:
    <p>Taspoglutide is a long-acting glucagon-like peptide 1 (GLP-1) receptor agonist(EC50 value of 0.06 nM),and for treatment of type 2 diabetes</p>
    Fórmula:C152H232N40O45
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3339.763
  • LSN3160440

    CAS:
    <p>LSN3160440 is a GLP-1R allosteric modulator and PPI stabilizer aiding inactive GLP-1 attachment.</p>
    Fórmula:C27H27Cl2N3O
    Cor e Forma:Solid
    Peso molecular:480.43
  • Des His1, Glu8 Exendin-4


    <p>Des His1, Glu8 Exendin-4 is a glucagon-like peptide-1 receptor (GLP1R) antagonist that regulates blood glucose and is used in the study of diabetes and obesity.</p>
    Fórmula:C179H277N47O59S
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:4063.46
  • Secretin, porcine

    CAS:
    <p>Porcine secretin: 27-amino acid peptide for diagnosing pancreatic dysfunction and gastrinoma, stimulates bicarbonate fluid.</p>
    Fórmula:C130H220N44O41·xC2H4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:N/A
  • TT-OAD2 free base

    CAS:
    <p>TT-OAD2 free base, a non-peptide GLP-1 receptor agonist, can treat diabetes; has an EC50 of 5 nM.</p>
    Fórmula:C50H47Cl2N3O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:856.83
  • {Val1}-Exendin-3/4


    <p>{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.</p>
    Fórmula:NA
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3241.7
  • GLP-1R agonist 14

    CAS:
    <p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>
    Fórmula:C45H42F2N10O5
    Cor e Forma:Solid
    Peso molecular:840.88
  • GIP/GLP-1 dual receptor agonist-1

    CAS:
    <p>Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.</p>
    Cor e Forma:Solid
  • HAEGTFTSDVS acetate


    <p>HAEGTFTSDVS acetate is the first N-terminal 1-11 residues of GLP-1 which stimulates insulin secretion from pancreatic β-cells.</p>
    Fórmula:C50H75N13O22
    Pureza:97.47%
    Cor e Forma:Solid
    Peso molecular:1210.2
  • GLP-1R agonist 29


    <p>GLP-1R agonist 29 (Compound 20) is a GLP-1R agonist that induces hGLP-1R-mediated cAMP stimulation with an EC50 of 0.018 nM. It exhibits favorable pharmacokinetic properties and shows good in vivo exposure, with an AUC0-∞,sc of 77688 ng·h/mL.</p>
    Cor e Forma:Odour Solid
  • Exendin-3/4 (59-86)


    <p>Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.</p>
    Fórmula:NA
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3055.49
  • GLP-1(7-37)

    CAS:
    <p>GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.</p>
    Fórmula:C151H228N40O47
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3355.67
  • Mazdutide acetate(2259884-03-0 free base)


    <p>Mazdutide acetate is a potent (GLP-1R and GCGR agonist that stimulates insulin secretion from mouse pancreatic islets , which can be used to study obesity.</p>
    Pureza:98.41%
    Cor e Forma:Odour Solid
  • Bay 55-9837

    CAS:
    <p>Selective VPAC2 agonist; EC50: 0.4 nM (VPAC2), 100 nM (VPAC1), &gt;1000 nM (PAC1). Enhances insulin secretion, reduces HIV-1 replication.</p>
    Fórmula:C167H270N52O46
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3742.29
  • Semaglutide TFA


    <p>Semaglutide TFA is a glucagon-like peptide-1 congener that induces weight loss, lowers blood glucose levels and reduces cardiovascular risk in diabetic patients</p>
    Fórmula:C189H290F3N45O61
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:4225.6482
  • Survodutide

    CAS:
    <p>Survodutide (BI 456906) is a dual agonist of glucagon and glucagon-like peptide 1 (GLP-1) receptor (GLP Receptor) that reduces body weight in HbA1c16 diabetes.</p>
    Fórmula:C192H289N47O61
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:4229.0957
  • VU0453379 hydrochloride


    <p>VU0453379 hydrochloride: selective CNS-penetrant GLP-1R PAM, EC50 1.3 μM.</p>
    Fórmula:C26H35ClN4O2
    Cor e Forma:Solid
    Peso molecular:471.03
  • 3-Deoxyglucosone

    CAS:
    <p>3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein</p>
    Fórmula:C6H10O5
    Pureza:95%
    Cor e Forma:Solid
    Peso molecular:162.14
  • Sorbinicate

    CAS:
    <p>Sorbinicate is an antihypercholesterolaemic and vasodilating nicotinic acid ester.</p>
    Fórmula:C42H32N6O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:812.74
  • Albiglutide fragment TFA


    <p>Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a</p>
    Fórmula:C148H224N40O45·xC2HF3O2
    Cor e Forma:Solid
  • (R)-V-0219 hydrochloride


    <p>(R)-V-0219 hydrochloride: Oral GLP-1R PAM, enantiomer of V-0219, triggers Ca2+ flux in hGLP-1R HEK cells.</p>
    Fórmula:C20H26ClF3N4O2
    Cor e Forma:Solid
    Peso molecular:446.89
  • Maridebart

    CAS:
    <p>Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].</p>
    Cor e Forma:Liquid
  • Oxyntomodulin

    CAS:
    <p>GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.</p>
    Fórmula:C192H295N59O60S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4421.86
  • GLP-1 receptor agonist 8

    CAS:
    <p>GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.</p>
    Fórmula:C34H36ClFN6O4
    Cor e Forma:Solid
    Peso molecular:647.14
  • [Des-His1,Glu9]-Glucagon amide

    CAS:
    <p>Glucagon blocker with pA2 of 7.2; no agonist effect. Boosts insulin; prevents glucagon-driven hyperglycemia in rabbits and diabetic rats.</p>
    Fórmula:C148H221N41O47S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3358.68
  • GLP-1R agonist 27


    <p>GLP-1R agonist 27 (compound 21) is a potent and orally active GLP-1R agonist. It enhances the accumulation of cyclic adenosine monophosphate (cAMP), reduces blood glucose levels, and decreases food intake. GLP-1R agonist 27 shows potential for research in obesity and type 2 diabetes mellitus (T2DM).</p>
    Fórmula:C32H33N5O4Se
    Cor e Forma:Solid
    Peso molecular:630.6
  • (S)-V-0219 hydrochloride


    <p>(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.</p>
    Fórmula:C20H26ClF3N4O2
    Cor e Forma:Solid
    Peso molecular:446.89
  • GLP-1R agonist 15

    CAS:
    <p>GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .</p>
    Fórmula:C46H47FN8O7S
    Cor e Forma:Solid
    Peso molecular:874.98
  • Gulgafafusp alfa

    CAS:
    <p>Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].</p>
    Cor e Forma:Liquid
  • Anti-GLP-1R Antibody


    <p>Anti-GLP-1R Antibody is an anti-GLP-1R antibody that can be used for immunohistochemistry of paraffin sections.</p>
    Pureza:98.3% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.3% (SDS-PAGE); 97.2% (SEC-HPLC)
    Cor e Forma:Odour Liquid
  • SPN009


    <p>SPN009 (Sequence 3) is a GLP-1 receptor (GLP-1 Receptor) agonist, with an EC50 of 2.84 nM, and improves type 2 diabetes in DB/DB mouse models.</p>
    Fórmula:C191H299N45O59
    Peso molecular:4167.17798
  • Glucagon-like peptide 1 (1-37), human TFA


    <p>Human Glucagon-like peptide 1 (1-37) TFA is a potent GLP-1 receptor agonist derived from proglucagon.</p>
    Fórmula:C188H276N51F3O61
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4283.5
  • GLP-1R agonist 20


    <p>GLP-1R agonist 20 (Compound I-132) is an agonist of the glucagon-like peptide-1 receptor (GLP-1 receptor), with an EC50 value of 0.0162 nM.</p>
    Fórmula:C31H30Cl2F2N4O5
    Peso molecular:646.15613
  • GLP-1R agonist 16

    CAS:
    <p>Compound 115a, a GLP-1R agonist, effectively activates the GLP-1 receptor with an EC50 of 0.15 nM [1].</p>
    Fórmula:C50H58FN10O6P
    Cor e Forma:Solid
    Peso molecular:945.03
  • GLP-1R agonist 4

    CAS:
    <p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>
    Fórmula:C32H30ClF2N3O5
    Cor e Forma:Solid
    Peso molecular:610.05
  • SAR441255


    <p>SAR441255 is a potent unimolecular peptide that acts as a GLP-1/GIP/GCG receptor triagonist, demonstrating balanced activation across all three target receptors</p>
    Cor e Forma:Odour Solid
  • FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS


    <p>FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS is an Exendin-4 peptide derivative.</p>
    Cor e Forma:Solid
    Peso molecular:3692.15
  • Dapiglutide

    CAS:
    <p>Dapiglutide (ZP7570) is a long-acting GLP-1R &amp; GLP-2R dual agonist for SBS research.</p>
    Cor e Forma:Solid
  • GRPP (human)

    CAS:
    <p>GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.</p>
    Fórmula:C136H215N41O58S
    Cor e Forma:Solid
    Peso molecular:3384.47
  • Glucagon (1-29), bovine, human, porcine

    CAS:
    <p>Corynoxine B (Cory B) is a naturally occurring alkaloid isolated from Uncaria rhynchophylla (Miq. ) and is an autophagy inducer.</p>
    Fórmula:C153H225N43O49S
    Pureza:99.56% - 99.56%
    Cor e Forma:Solid
    Peso molecular:3482.75
  • GLP-1 receptor agonist 7

    CAS:
    <p>GLP-1 receptor agonist 7, potential for diabetes research, from patent WO2021219019A1.</p>
    Fórmula:C31H30ClFN4O5
    Cor e Forma:Solid
    Peso molecular:593.05
  • GLP-1 receptor agonist 2

    CAS:
    <p>GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>
    Fórmula:C30H31ClFN5O4
    Cor e Forma:Solid
    Peso molecular:580.05
  • V-0219

    CAS:
    <p>V-0219 is a positive allosteric modulator of GLP-1 and can be used in studies about obesity-associated diabetes.</p>
    Fórmula:C20H25F3N4O2
    Pureza:99.91%
    Cor e Forma:Soild
    Peso molecular:410.43
  • GLP-1R modulator C16

    CAS:
    <p>GLP-1R modulator C16 is a variable modulator that significantly increases the binding affinity of GLP-4.</p>
    Fórmula:C21H26ClFN2O3
    Pureza:99.6% - >99.99%
    Cor e Forma:Solid
    Peso molecular:408.89