Receptor Glucagon
Os receptores de glucagon são GPCRs que mediam os efeitos do glucagon, um hormônio envolvido na regulação da homeostase da glicose, promovendo a quebra de glicogênio e a liberação de glicose pelo fígado. Esses receptores são críticos na gestão dos níveis de açúcar no sangue e são de particular interesse no estudo do diabetes e distúrbios metabólicos. Antagonistas dos receptores de glucagon estão sendo explorados como potenciais tratamentos para hiperglicemia no diabetes tipo 2. Na CymitQuimica, oferecemos uma variedade de moduladores de receptores de glucagon de alta qualidade para apoiar sua pesquisa em endocrinologia, diabetes e regulação metabólica.
Foram encontrados 164 produtos de "Receptor Glucagon"
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Anti-GCGR Antibody (7J909)
<p>Anti-GCGR Antibody (7J909) is an antibody targeting GCGR. Anti-GCGR Antibody (7J909) can be used in ELISA.</p>Cor e Forma:Odour LiquidSCO-267
CAS:<p>SCO-267 is a full agonist of GPR40/FFAR1， stimulating insulin secretion and GLP-1 release in diabetic rats, improving glucose tolerance,type 2 diabetes.</p>Fórmula:C36H46N4O5Pureza:99.89%Cor e Forma:SolidPeso molecular:614.77GLP-1R modulator C5
CAS:<p>GLP-1R modulator C5 is a GLP-1R modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.</p>Fórmula:C24H21NO3Pureza:99.59%Cor e Forma:SolidPeso molecular:371.43Liraglutide
CAS:<p>Liraglutide (Liraglutida) is a synthetic analog of GLP-1, an agonist of the GLP-1 receptor. Liraglutide is an antidiabetic agent. Cost effective and quality assured.</p>Fórmula:C172H265N43O51Pureza:97.65% - 99.04%Cor e Forma:SolidPeso molecular:3751.25PF-06882961 Tris
CAS:<p>PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.</p>Fórmula:C35H41FN6O7Pureza:98.74% - 99.79%Cor e Forma:SolidPeso molecular:676.7GRA Ex-25
CAS:<p>GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor.</p>Fórmula:C29H36F3N3O5Pureza:98.2% - 98.88%Cor e Forma:SolidPeso molecular:563.61Shanzhiside methyl ester
CAS:<p>Shanzhiside methylester soothes neuropathic pain by triggering spinal GLP-1 receptors, boosting microglial β-endorphin through p38 MAPK.</p>Fórmula:C17H26O11Pureza:98.998% - 99.32%Cor e Forma:SolidPeso molecular:406.38Lixisenatide acetate (320367-13-3 free base)
CAS:<p>Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).</p>Fórmula:C215H347N61O65S·6C2H4O2Pureza:98% - 99.9%Cor e Forma:SolidPeso molecular:5218.88BETP
CAS:<p>BETP is an agonist of GLP-1 receptor (EC50s: 0.66 and 0.755 μM for human and rat GLP-1 receptor).</p>Fórmula:C20H17F3N2O2SPureza:98.51%Cor e Forma:SolidPeso molecular:406.42HAEGTFTSDVSSYLE
<p>HAEGTFTSDVSSYLE is a peptide. GLP-I analog contains the sequence.</p>Fórmula:C71H103N17O28Pureza:>99.99%Cor e Forma:SolidPeso molecular:1642.71GLP-1(7-36), amide
CAS:<p>GLP-1 secretion by human enteroendocrine NCI-H716 cells is augmented in a dose-dependent manner by the addition of CPE.Cost-effective and quality-assured.</p>Fórmula:C149H226N40O45Pureza:99.85%Cor e Forma:White PowderPeso molecular:3297.63Exendin-4
CAS:<p>Exenatide: GLP-1 receptor agonist, 39-amino acid, longer half-life (2.4 hrs), IC50 of 3.22 nM.</p>Fórmula:C184H282N50O60SPureza:97.71% - 99.78%Cor e Forma:SolidPeso molecular:4186.57Semaglutide
CAS:<p>Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).</p>Fórmula:C187H291N45O59Pureza:96.92% - 99.78%Cor e Forma:SolidPeso molecular:4114Exendin-4 acetate
CAS:<p>Exendin-4 acetate is a 39 amino acid peptide.Exendin-4 acetate is a long-acting GLP-1 receptor agonist(IC50 = 3.22 nM).</p>Fórmula:C186H286N50O62SPureza:98.48% - 99.78%Cor e Forma:SolidPeso molecular:4247Oxyntomodulin acetate
<p>Oxyntomodulin acetate, a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist[1].</p>Pureza:99.24%Cor e Forma:LiquidPeso molecular:N/ABay 55-9837 acetate
<p>Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.</p>Pureza:98.27%Cor e Forma:LiquidPeso molecular:N/ASecretin (33-59), rat
CAS:<p>Secretin (33-59), rat (Secretin (rat)) is a classical hormone in the gastrointestinal system and a neuropeptide.</p>Fórmula:C129H216N42O42Pureza:98.12%Cor e Forma:SolidPeso molecular:3027.35Glucagon (19-29), human acetate
<p>Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion.</p>Fórmula:C63H93N15O20SPureza:98.11%Cor e Forma:SolidPeso molecular:1412.57HAEGTFT acetate(926018-95-3 free base)
<p>HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.</p>Fórmula:C35H51N9O14Pureza:>99.99%Cor e Forma:SolidPeso molecular:821.84Tirzepatide Acetate(2023788-19-2 free base)
<p>Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels.Cost-effective and quality-assured.</p>Fórmula:C227H352N48O70Pureza:97.3% - 98.05%Cor e Forma:SolidPeso molecular:4873.5Albiglutide TFA (782500-75-8 free base)
<p>Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM).</p>Fórmula:C150H225F3N40O47Pureza:>99.99%Cor e Forma:SolidPeso molecular:3397.63Teduglutide acetate
<p>Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.</p>Fórmula:C166H256N44O56SPureza:97.39%Cor e Forma:SoildPeso molecular:3812.13ML-SI3
CAS:<p>CCG-143140 is a GLP-1 receptor inverse agonists.</p>Fórmula:C23H31N3O3SPureza:99.75%Cor e Forma:SolidPeso molecular:429.58Exenatide
CAS:<p>Exenatide (Extendin-4) is a glucagon-like protein-1 (GLP-1) receptor agonist.</p>Fórmula:C186H286N50O62SPureza:99.42%Cor e Forma:SolidPeso molecular:4247Glucagon-like peptide 1 (1-37), human acetate
<p>Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist.</p>Pureza:98%Cor e Forma:LiquidPeso molecular:N/ACotadutide acetate
<p>Cotadutide acetate is a potent GLP-1 and glucagon receptor dual agonist with EC50s of 6.9 pM and 10.2 pM.</p>Fórmula:C169H256N42O57Pureza:98.28%Cor e Forma:SolidPeso molecular:3788.14GLP-1(7-37) acetate(106612-94-6 free base)
CAS:<p>Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.</p>Fórmula:C151H228N40O47Pureza:98.89%Cor e Forma:SolidPeso molecular:3355.67Avexitide
CAS:<p>Avexitide (Exendin-3 (9-39) amide) (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.</p>Fórmula:C149H234N40O47SPureza:98% - 99.65%Cor e Forma:SolidPeso molecular:3369.76GLP-1 receptor agonist 9
CAS:<p>1H-Benzimidazole-6-carboxylic acid is a GLP-1 receptor agonist.</p>Fórmula:C32H31ClFN3O5Pureza:98%Cor e Forma:SolidPeso molecular:592.06PF-06291874
CAS:<p>PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.</p>Fórmula:C26H28F3N3O4Pureza:99.12% - 99.27%Cor e Forma:SolidPeso molecular:503.51NNC-0640
CAS:<p>NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.</p>Fórmula:C29H31N7O4SPureza:97.04%Cor e Forma:SolidPeso molecular:573.67Glucagon receptor antagonists-5
CAS:<p>Oral indazole-based glucagon antagonist, Ki: 32 nM, may treat type 2 diabetes.</p>Fórmula:C30H29ClF3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:572.02BAY-27-9955
CAS:<p>BAY-27-9955 is a glucagon receptor antagonist.</p>Fórmula:C23H31FOCor e Forma:SolidPeso molecular:342.49(R)-V-0219
<p>(R)-V-0219: GLP-1R PAM, orally active, triggers Ca++ flux in HEK-hGLP-1R cells.</p>Fórmula:C20H25F3N4O2Cor e Forma:SolidPeso molecular:410.43GLP-1R agonist 1
CAS:<p>GLP-1R agonist 1, an imidazole derivative and potent GLP-1R activator, may aid diabetes research.</p>Fórmula:C32H29ClFN3O5Cor e Forma:SolidPeso molecular:590.04Glucagon receptor antagonists-2
CAS:<p>Glucagon receptor antagonist -2 is a highly effective glucagon receptor antagonist.</p>Fórmula:C22H30FNO2Pureza:98%Cor e Forma:SolidPeso molecular:359.48MS012
CAS:<p>MS012 is a Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase (Kd = 46 ± 15 nM).</p>Fórmula:C22H35N5O2Cor e Forma:SolidPeso molecular:401.55(S)-V-0219
<p>(S)-V-0219: oral, GLP-1R PAM, boosts calcium in hGLP-1R HEK cells, lowers glucose, curbs hunger in mice.</p>Fórmula:C20H25F3N4O2Cor e Forma:SolidPeso molecular:410.43GCGR antagonist 2
CAS:<p>Orally active GCGR antagonist 2, a furan-2-carbohydrazide, binds hGluR at 2.3 nM. Blocks glucagon, inhibits rat receptor at 0.43 nM.</p>Fórmula:C28H26N4O2Cor e Forma:SolidPeso molecular:450.53NNC 92-1687
CAS:<p>NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.</p>Fórmula:C15H12N2O3SPureza:98.70% - 99.70%Cor e Forma:SolidPeso molecular:300.33L-168049
CAS:<p>L-168049: Human glucagon receptor antagonist, IC50 - 3.7 nM human, 63 nM murine, 60 nM canine.</p>Fórmula:C24H20BrClN2OPureza:>99.99%Cor e Forma:SolidPeso molecular:467.79GLP-1R agonist 9
CAS:<p>GLP-1R agonist 9 acts as a GLP-1R agonist, demonstrating efficacy with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and Clone C6, respectively.</p>Fórmula:C32H30ClF2N3O5Cor e Forma:SolidPeso molecular:610.05GLP-1R agonist 17
CAS:<p>GLP-1R agonist 17 excels in stimulating GLP-1 receptors, useful for cardiovascular metabolic disease research.</p>Fórmula:C28H26ClFN4O4SCor e Forma:SolidPeso molecular:569.05Glucagon receptor antagonists-3
CAS:<p>Glucagon receptor antagonist -3 is a highly effective glucagon receptor antagonist.</p>Fórmula:C22H30FNO2Pureza:98%Cor e Forma:SolidPeso molecular:359.48GLP-1 receptor agonist 3
CAS:<p>GLP-1 receptor agonist 3 is a GLP-1 receptor agonist,Example 4A-1, has EC50s of 1.1 nM and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively.</p>Fórmula:C31H30FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:555.6GLP-1R agonist 12
CAS:<p>GLP-1R agonist 12 (Compound 123) 是一种 GLP-1R 激动剂，能够用于研究糖尿病。</p>Fórmula:C34H36N6O4Cor e Forma:SolidPeso molecular:592.69LGD-6972 sodium
CAS:<p>LGD-6972 sodium is a glucagon receptor antagonist.</p>Fórmula:C43H46N2NaO5SPureza:98%Cor e Forma:SolidPeso molecular:725.9Antitumor agent-101
CAS:<p>Antitumor agent-101 is a selective, covalent inhibitor targeting lysine methyltransferases G9a/GLP, demonstrating IC50 values of 8.5 nM for G9a and 5.5 nM for</p>Fórmula:C26H38N6O3Pureza:98%Cor e Forma:SolidPeso molecular:482.62MK 0893
CAS:<p>MK 0893 is a potent and selective Glucagon Receptor (GR) antagonist competitive, reversible cAMP activity, which attenuates blood glucose elevation.</p>Fórmula:C32H27Cl2N3O4Pureza:98.79%Cor e Forma:SolidPeso molecular:588.48MK3577
CAS:<p>MK3577 is a glucagon receptor antagonist.</p>Fórmula:C30H30ClFN2O3Cor e Forma:SolidPeso molecular:521.02GLP-1R agonist 3
CAS:<p>GLP-1R agonist 3 is a GLP-1R agonist, an imidazole derivative.GLP-1R agonist 3 can be used to study diabetes and obesity.</p>Fórmula:C31H28FN5O4Pureza:97.19%Cor e Forma:SolidPeso molecular:553.58GLP-1R agonist 10
CAS:<p>GLP-1R agonist 10 is a GLP-1 agonist (EC50: 0.051 nM).</p>Fórmula:C29H29ClFN5O4Cor e Forma:SolidPeso molecular:566.02LGD-6972
CAS:<p>LGD-6972 is an antagonist of glucagon receptor.</p>Fórmula:C43H46N2O5SPureza:98.8% - 99.62%Cor e Forma:SolidPeso molecular:702.9Lotiglipron
CAS:<p>Lotiglipron (PF-07081532) is a GLP-1R agonist that lowers blood glucose and may be used in the study of type 2 diabetes mellitus (T2DM) and excess obesity.</p>Fórmula:C31H31ClN4O5Pureza:98.3%Cor e Forma:SolidPeso molecular:575.05Adomeglivant
CAS:<p>Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.</p>Fórmula:C32H36F3NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:555.63PF-06372222
CAS:<p>PF-06372222: a small-molecule that modulates GCGR and antagonizes GLP-1R, affecting insulin and glucagon.</p>Fórmula:C26H28F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:515.53GLP-1 receptor agonist 11
CAS:<p>GLP-1 Receptor Agonist 11 (compound 3) acts as an effective agonist for the GLP Receptor, finding use in research related to conditions like diabetes and non-alc. fatty liver disease [1].</p>Fórmula:C31H31ClFN3O4Cor e Forma:SolidPeso molecular:564.05GLP-1 receptor agonist 16
CAS:<p>GLP-1 receptoragonist 16 (Example 53) is a GLP-1 agonist applicable for research in diabetes, obesity, or diseases related to non-alcoholic steatohepatitis.</p>Fórmula:C33H31ClFN3O4Cor e Forma:SolidPeso molecular:588.068GLP-1 receptor agonist 15
CAS:<p>GLP-1 receptor agonist 15 (Example 4) is a GLP receptor agonist with an EC50 of 0.74 nM. It exhibits an IC50 of 10.1 μM against the hERG potassium ion channel. This compound is applicable for research in the diabetes field.</p>Fórmula:C32H31ClFN3O5Cor e Forma:SolidPeso molecular:592.057SCH-900822
CAS:<p>SCH-900822 is a potent and selective glucagon receptor antagonist.</p>Fórmula:C34H43Cl2N7O2Cor e Forma:SolidPeso molecular:652.66GLP-1R agonist 8
CAS:<p>GLP-1R agonist 8 is a potent agonist of GLP-1R (EC50 < 2 nM).</p>Fórmula:C33H32N4O5Cor e Forma:SolidPeso molecular:564.63DS79932728
CAS:<p>DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.</p>Fórmula:C19H25N3OCor e Forma:SolidPeso molecular:311.421DA-302168S
CAS:<p>DA-302168S is an orally active, selective GLP-1R agonist with an EC50 value of 1.32 nM. It promotes insulin secretion and has a hypoglycemic effect. Additionally, DA-302168S reduces food intake. It primarily activates GLP-1R in humans and monkeys, with minimal effect on GLP-1R in rats, mice, and dogs. DA-302168S can be used for research in type 2 diabetes and obesity.</p>Fórmula:C33H24ClF2N3O5Cor e Forma:SolidPeso molecular:616.011LSN3318839
CAS:<p>LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can</p>Fórmula:C26H23Cl2N3O2Pureza:99.21%Cor e Forma:SolidPeso molecular:480.39
