Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
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TC-C 14G
CAS:<p>CB1 receptor inverse agonist</p>Fórmula:C24H17Cl2F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:492.3ZCZ011
CAS:<p>ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.</p>Fórmula:C21H18N2O2SPureza:98%Cor e Forma:SolidPeso molecular:362.44(S)-SLV 319
CAS:<p>Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.</p>Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4COR167
CAS:<p>COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.</p>Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61CID1172084
CAS:<p>CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.</p>Fórmula:C23H18FN5O2S2Cor e Forma:SolidPeso molecular:479.55O-2093
CAS:<p>anandamide uptake inhibitor</p>Fórmula:C34H43Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:584.62GAT228
CAS:<p>GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].</p>Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39CB1 inverse agonist 2
CAS:<p>CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.</p>Fórmula:C24H20ClFN2OSCor e Forma:SolidPeso molecular:438.94CB2R agonist 1
CAS:<p>CB2R agonist 1 selectively binds human CB2R, EC50 of 0.56 µM, modulates inflammatory cytokines.</p>Fórmula:C22H32N2OCor e Forma:SolidPeso molecular:340.5LEI 101 hydrochloride
CAS:<p>LEI 101 hydrochloride is potent and selective CB2 partial agonist.</p>Fórmula:C23H26ClFN4O4SCor e Forma:SolidPeso molecular:508.99ANEB-001
CAS:<p>ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.</p>Fórmula:C22H24ClF3N2O2Cor e Forma:SolidPeso molecular:440.89CB1R Allosteric modulator 2
CAS:<p>Compound 18 is a potent CB1R allosteric modulator that acts as a negative modulator (NAM) for CB1R orthosteric ligands.</p>Fórmula:C19H15ClFN3OCor e Forma:SolidPeso molecular:355.79COR 170
CAS:<p>inverse agonist of CB2 receptors</p>Fórmula:C31H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:468.63CB1/2 agonist 2
CAS:<p>CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.</p>Fórmula:C26H43NO3Cor e Forma:SolidPeso molecular:417.62PGN36
CAS:<p>PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43CB1R Allosteric modulator 1
CAS:<p>CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.</p>Fórmula:C24H24ClN3OCor e Forma:SolidPeso molecular:405.92S-777469
CAS:<p>S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.</p>Fórmula:C23H27FN2O4Cor e Forma:SolidPeso molecular:414.47CB2 receptor agonist 3
CAS:<p>GP 2A is a selective agonist of CB2 receptor.</p>Fórmula:C24H23Cl2N3OCor e Forma:SolidPeso molecular:440.36Virodhamine trifluoroacetate
CAS:<p>Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.</p>Fórmula:C24H38F3NO4Pureza:98%Cor e Forma:SolidPeso molecular:461.56LBP-1
CAS:<p>LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.</p>Fórmula:C23H29ClN6O3Cor e Forma:SolidPeso molecular:472.97MM-22
CAS:<p>biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide</p>Fórmula:C36H60N4O5SPureza:98%Cor e Forma:SolidPeso molecular:660.95KLS-13019
CAS:<p>KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).</p>Fórmula:C22H29NO3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:355.47OMDM-6
CAS:<p>OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.</p>Fórmula:C28H42N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:454.64N-Arachidonyldopamine
CAS:<p>N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1</p>Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.63CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36AM6545
CAS:<p>AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.</p>Fórmula:C26H23Cl2N5O3SPureza:97.03%Cor e Forma:SolidPeso molecular:556.46Arvanil
CAS:<p>Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.</p>Fórmula:C28H41NO3Pureza:99.49%Cor e Forma:SolidPeso molecular:439.63MJ 15
CAS:<p>MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.</p>Fórmula:C23H17Cl3N4OPureza:99.63%Cor e Forma:SolidPeso molecular:471.77AZD1940
CAS:<p>AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.</p>Fórmula:C20H29F2N3O2SPureza:98.68%Cor e Forma:SolidPeso molecular:413.52JTE-907
CAS:<p>JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。</p>Fórmula:C24H26N2O6Pureza:99.93%Cor e Forma:SolidPeso molecular:438.47CB1 agonist 1
CAS:<p>CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.</p>Fórmula:C24H24N2O5SPureza:98.56%Cor e Forma:SolidPeso molecular:452.52SCH-336
CAS:<p>SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.</p>Fórmula:C23H25NO8S3Pureza:95.01%Cor e Forma:SolidPeso molecular:539.64Olorinab
CAS:<p>Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.</p>Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:SolidPeso molecular:357.41SR144528
CAS:<p>SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).</p>Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05PSB-CB5
CAS:<p>PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Fórmula:C20H17ClN2O2SPureza:99.26%Cor e Forma:SolidPeso molecular:384.88CB2R PAM
CAS:<p>CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.</p>Fórmula:C21H24BrFN2O2Pureza:99.09%Cor e Forma:SolidPeso molecular:435.33AM-1235
CAS:<p>AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.</p>Fórmula:C24H21FN2O3Pureza:97.77%Cor e Forma:SolidPeso molecular:404.43CB1R antagonist 1
CAS:<p>CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.</p>Fórmula:C18H23F3N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:404.45Nonabine
CAS:<p>Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.</p>Fórmula:C25H33NO2Pureza:99.46% - 99.95%Cor e Forma:SolidPeso molecular:379.54CAY10508
CAS:<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Fórmula:C21H14Br2N2O2Cor e Forma:SolidPeso molecular:486.2PF-03550096
CAS:<p>PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].</p>Fórmula:C19H28N4O4Cor e Forma:SolidPeso molecular:376.45COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82CB1 antagonist 1
CAS:<p>CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and</p>Fórmula:C26H22Cl2N4Pureza:98%Cor e Forma:SolidPeso molecular:461.39Heptadecanoyl ethanolamide
CAS:<p>Heptadecanoyl ethanolamide, an endogenous cannabinoid, serves as a synthetic analog of PEA, featuring an odd-numbered (17-carbon) fatty acid chain [1].</p>Fórmula:C19H39NO2Cor e Forma:SolidPeso molecular:313.52AM841
CAS:<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66(R)-Monlunabant
CAS:<p>(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].</p>Fórmula:C26H22ClF3N6O3SPureza:98%Cor e Forma:SolidPeso molecular:591GSK-554418A
CAS:<p>GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.</p>Fórmula:C19H19ClN4O2Cor e Forma:SolidPeso molecular:370.83CB 65
CAS:<p>CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.</p>Fórmula:C22H28ClN3O3Pureza:98.73%Cor e Forma:SolidPeso molecular:417.93O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Fórmula:C23H36O3Cor e Forma:SolidPeso molecular:360.53OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:432.64O-2050
CAS:<p>O-2050: strong CB1 antagonist (Ki 2.5 nM), CB2 inhibitor (Ki 0.2 nM); reduces mouse food intake, increases activity.</p>Fórmula:C23H31NO4SPureza:98%Cor e Forma:SolidPeso molecular:417.56GW405833 hydrochloride
CAS:<p>GW405833 hydrochloride, a potent and selective agonist of the cannabinoid-2 (CB2) receptor (EC 50 = 0.65 nM; maximum inhibition = 44.6%), exhibits significant antihyperalgesic effects in various rodent pain models [1] [2] [3].</p>Fórmula:C23H25Cl3N2O3Cor e Forma:SolidPeso molecular:483.822-Linoleoyl Glycerol
CAS:<p>2-Arachidonoyl glycerol (2-AG), a natural endocannabinoid ligand for the CB1 receptor, was isolated from porcine brain and characterized. Its congener, 2-linoleoyl glycerol (2-LG), which has a linoleoyl group instead of an arachidonoyl group, also exists alongside 2-AG in vivo. While 2-LG exhibits low intrinsic activity, it enhances the activity of 2-AG and other endocannabinoids through an "entourage" effect, attributed to the inhibition of breakdown and reuptake pathways that typically decrease endocannabinoid levels post-release.</p>Fórmula:C21H38O4Cor e Forma:SolidPeso molecular:354.531CB1 inverse agonist 1
CAS:<p>MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.</p>Fórmula:C25H18Cl3N3O3Pureza:99.92%Cor e Forma:SolidPeso molecular:514.79Hemopressin(rat) TFA
CAS:<p>Hemopressin(rat) TFA, a nonapeptide from hemoglobin α1-chain, selectively inhibits CB1 receptors and reduces inflammatory pain.</p>Fórmula:C55H78F3N13O14Cor e Forma:SolidPeso molecular:1202.28CB-25
CAS:<p>CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cells</p>Fórmula:C25H41NO3Pureza:98%Cor e Forma:SolidPeso molecular:403.6γ-Linolenoyl monoethanolamide
CAS:<p>γ-Linolenoyl monoethanolamide, a fatty N-acyl ethanolamine, acts as an endocannabinoid [1] [2].</p>Fórmula:C20H35NO2Cor e Forma:SolidPeso molecular:321.505Tedalinab
CAS:<p>Tedalinab is an effective and selective cannabinoid receptor 2 agonist.</p>Fórmula:C19H21F2N3OPureza:98%Cor e Forma:SolidPeso molecular:345.39Prostaglandin E2-1-glyceryl ester
CAS:<p>Prostaglandin E2-1-glyceryl ester, a member of the Prostaglandin Glycerol Ester family, serves as an endocannabinoid ligand targeting the CB1 receptor. This compound triggers a swift and transient surge in intracellular free calcium levels [1] [2].</p>Fórmula:C23H38O7Cor e Forma:SolidPeso molecular:426.55PSB-SB1202
CAS:<p>PSB-SB1202 (Compound 21a), a phenyl coumarin compound, acts as a CB1/CB2 agonist. It demonstrates EC50 values of 56 and 14 nM and K i values of 32 and 49 nM for CB1 and CB2 receptors, respectively [1].</p>Fórmula:C23H26O4Cor e Forma:SolidPeso molecular:366.45CB2R-IN-1
CAS:<p>CB2R-IN-1 is a potent inverse agonist of the cannabinoid CB2 receptor (Ki: 0.9 nM).</p>Fórmula:C23H27F3N4O6S3Pureza:98%Cor e Forma:SolidPeso molecular:608.67CB-52
CAS:<p>CB-52 acts as a neutral antagonist and ligand for the CB2 cannabinoid receptor [1].</p>Fórmula:C26H43NO3Cor e Forma:SolidPeso molecular:417.62URB447
CAS:<p>URB447, a peripherally restricted CB1 cannabinoid antagonist with IC50 values of 313 nM for rat CB1 receptor and 41 nM for human CB2 receptor, effectively reduces food intake and body weight gain in mice. It achieves these effects without penetrating the brain or antagonizing central CB1-dependent responses, making it a potential research tool for obesity studies [1].</p>Fórmula:C25H21ClN2OCor e Forma:SolidPeso molecular:400.9Isopropyl dodec-11-enylfluorophosphonate
CAS:<p>Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits</p>Fórmula:C15H30FO2PPureza:98%Cor e Forma:SolidPeso molecular:292.37Amauromine
CAS:<p>Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.</p>Fórmula:C32H36N4O2Cor e Forma:SolidPeso molecular:508.65PSNCBAM-1
CAS:<p>PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.</p>Fórmula:C22H21ClN4OPureza:99.86%Cor e Forma:SolidPeso molecular:392.88PF 514273
CAS:<p>PF 514273 is a CB1 receptor antagonist.</p>Fórmula:C21H17Cl2F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:452.28GSK494581A
CAS:<p>GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.</p>Fórmula:C27H28F2N2O4SPureza:98%Cor e Forma:SolidPeso molecular:514.58GP 1a
CAS:<p>GP 1a: potent CB2 receptor agonist (EC50=7.1), 30x CB2 over CB1 preference, boosts P-ERK1/2, aids skin healing, anti-inflammatory.</p>Fórmula:C23H22Cl2N4OPureza:99.79%Cor e Forma:SolidPeso molecular:441.35GW 833972A
CAS:<p>GW 833972A: selective CB2 agonist; reduces neural depolarization and citric acid cough in animals.</p>Fórmula:C18H14Cl2F3N5OPureza:99.93%Cor e Forma:SoildPeso molecular:444.24MDA7
CAS:<p>MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.</p>Fórmula:C22H25NO2Cor e Forma:SolidPeso molecular:335.439MDMB-FUBICA
CAS:<p>MDMB-FUBICA is a potent agonist of the cannabinoid receptors and exhibits psychoactive properties. It can be utilized in e-cigarettes.</p>Fórmula:C23H25FN2O3Cor e Forma:SolidPeso molecular:396.455BNS808
CAS:<p>BNS808 is an orally active, selective CB1R antagonist with an IC50 of 0.8 nM, demonstrating significant selectivity for CB2R and minimal brain penetration. It is being studied for the treatment of obesity and related metabolic complications, such as metabolic dysfunction-associated steatotic liver disease (MASLD). BNS808 reduces drug exposure to the central nervous system, enhancing safety, and minimizes drug interactions through high plasma protein binding.</p>Fórmula:C25H20Cl3N3O3SCor e Forma:SolidPeso molecular:548.869CB1/2 receptor-1
CAS:<p>CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.</p>Fórmula:C33H48O2Cor e Forma:SolidPeso molecular:476.73BAY 38-7271
CAS:<p>BAY 38-7271: potent neuroprotective, selective CB1/CB2 agonist, Ki of 1.85 nM (CB1) & 5.96 nM (CB2).</p>Fórmula:C20H21F3O5SPureza:98%Cor e Forma:SolidPeso molecular:430.44GAT564
<p>GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.</p>Fórmula:C20H16N2O2SCor e Forma:SolidPeso molecular:348.42Bzo-poxizid
CAS:<p>Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.</p>Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.40HU-308
CAS:<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.62CB1/2 agonist 1
<p>Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.</p>Fórmula:C21H24BrFN2O2Cor e Forma:SolidPeso molecular:435.33TM38837
CAS:<p>CB1 antagonist 4 is an inverse agonist of cannabinoid receptor 1 (CB1) with an IC50 of 0.4 nM. It can reduce body weight, improve plasma inflammatory markers, and enhance glucose homeostasis [1].</p>Fórmula:C27H20Cl2F3N7OCor e Forma:SolidPeso molecular:586.40CB2 receptor antagonist 1
CAS:<p>Compound 29 is a potent, CB2-selective antagonist/reverse agonist. Derivatives 23 & 24 offer antinociception; 24 activates cannabinoid/TRPV1 receptors.</p>Fórmula:C28H47NO3Cor e Forma:SolidPeso molecular:445.68Taranabant
CAS:<p>Taranabant: potent CB1 receptor inverse agonist; inhibits agonists with 0.13 nM Ki in vitro.</p>Fórmula:C27H25ClF3N3O2Pureza:99.06% - 99.06%Cor e Forma:SolidPeso molecular:515.96CBR Agonist-2
<p>CBR Agonist-2: CB1 receptor agonist, EC50 - 960 nM, Ki - 970 nM, useful for hCB1R-related disease research.</p>Fórmula:C27H27FN4OCor e Forma:SolidPeso molecular:442.53CBR Agonist-1
<p>CBR Agonist-1 targets CB1R and CB2R with Ki of 0.18 μM and 1.22 μM, useful for studying cannabinoid-related diseases.</p>Fórmula:C27H27FN4OCor e Forma:SolidPeso molecular:442.53HU 433
CAS:<p>HU 433, a synthetic cannabinoid, acts as a CB2 receptor agonist and is an enantiomer of HU 308. It provides anti-inflammatory and neuroprotective effects by binding to the CB2 receptor, primarily found on immune cells, thereby modulating immune responses and inflammation. Additionally, HU 433 influences microglial signaling pathways, particularly LPS and IFNγ-mediated routes, affecting the phosphorylation of MAPKs, including ERK1/2, JNK, p38, and Akt. This compound is valuable in researching neuroinflammation and retinal diseases.</p>Fórmula:C27H42O3Cor e Forma:SolidPeso molecular:414.621'-Naphthoyl-2-methylindole
CAS:<p>1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.</p>Fórmula:C20H15NOCor e Forma:SolidPeso molecular:285.34FDU-PB-22
CAS:<p>FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.</p>Fórmula:C26H18FNO2Cor e Forma:SolidPeso molecular:395.43MDA77
CAS:<p>MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43O-1269
CAS:<p>O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.</p>Fórmula:C22H22Cl3N3OCor e Forma:SolidPeso molecular:450.79AB-FUBINACA 3-fluorobenzyl isomer
CAS:<p>AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.</p>Fórmula:C20H21FN4O2Cor e Forma:SolidPeso molecular:368.41AM8936
<p>AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.</p>Fórmula:C25H33NO3Cor e Forma:SolidPeso molecular:395.53(Rac)-Zevaquenabant
CAS:<p>(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), with a binding affinity (Ki) of 5.7 nM for CB1R. It holds promise as an investigative tool in liver fibrosis research due to these characteristics.</p>Fórmula:C25H21ClF3N5O2SCor e Forma:SolidPeso molecular:547.98WIN 55,212-2 Mesylate
CAS:<p>WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. Cannabinoid analogue WIN 55,212-2 Mesylate exhibited a novel anticancer effect against human tumors.</p>Fórmula:C28H30N2O6SPureza:98% - 99.71%Cor e Forma:White To Off-White SolidPeso molecular:522.61AM-2232
CAS:<p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.432-Arachidonoylglycerol
CAS:<p>In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand</p>Fórmula:C23H38O4Pureza:95%Cor e Forma:LiquidPeso molecular:378.55Ref: TM-T14011
Produto descontinuadoAEF0117
CAS:<p>AEF0117 is a signaling inhibitor of CB1-SSi that inhibits cannabinoid self-administration and can be used to study cannabis withdrawal.</p>Fórmula:C29H40O3Pureza:99.58%Cor e Forma:SolidPeso molecular:436.63
