Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
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Linoleoyl Ethanolamide
CAS:<p>Linoleoyl Ethanolamide is an endocannabinoid agent.</p>Fórmula:C20H37NO2Pureza:99.97%Cor e Forma:SolidPeso molecular:323.51Otenabant
CAS:<p>Otenabant (CP-945598) has been investigated for the treatment of Obesity.</p>Fórmula:C25H25Cl2N7OPureza:99.43%Cor e Forma:SolidPeso molecular:510.42CB1 antagonist 4
CAS:<p>TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.</p>Fórmula:C30H25Cl2F3N4OSPureza:98.97%Cor e Forma:SolidPeso molecular:617.51LY2828360
CAS:<p>LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.</p>Fórmula:C22H27ClN6OPureza:98.45% - 99.51%Cor e Forma:SolidPeso molecular:426.94A-836339
CAS:<p>A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.</p>Fórmula:C16H26N2O2SPureza:99.94%Cor e Forma:SolidPeso molecular:310.45Tetrahydromagnolol
CAS:<p>Tetrahydromagnolol can activate cannabinoid (CB) receptors.</p>Fórmula:C18H22O2Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:270.37CB1-IN-1
CAS:<p>CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.</p>Fórmula:C33H31Cl2F3N6O3S2Pureza:99.08% - 99.76%Cor e Forma:SolidPeso molecular:751.67ML-193
CAS:<p>ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.</p>Fórmula:C28H25N5O4SPureza:97.74%Cor e Forma:SolidPeso molecular:527.59Otenabant hydrochloride
CAS:<p>Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).</p>Fórmula:C25H26Cl3N7OPureza:99.79% - ≥95%Cor e Forma:SolidPeso molecular:546.88Cannabigerol
CAS:<p>Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also</p>Fórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48AM251
CAS:<p>AM251: potent CB1 blocker (IC50: 8 nM), 306x CB2 selective; GPR55 activator (EC50: 39 nM).</p>Fórmula:C22H21Cl2IN4OPureza:97.43% - 98.79%Cor e Forma:A Crystalline SolidPeso molecular:555.24Hemopressin (human, mouse) acetate
<p>Hemopressin: Nonapeptide, α1-hemoglobin derivative, CB1 inverse agonist, isolated from rats, oral, reduces inflammatory pain.</p>Fórmula:C52H83N13O14Pureza:99.86%Cor e Forma:SolidPeso molecular:1114.29ARN272
CAS:<p>ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).</p>Fórmula:C27H20N4O2Pureza:98.23%Cor e Forma:SolidPeso molecular:432.47Voacamine
CAS:<p>Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.</p>Fórmula:C43H52N4O5Pureza:98.54% - 99.82%Cor e Forma:SolidPeso molecular:704.9AM1241
CAS:<p>AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.</p>Fórmula:C22H22IN3O3Pureza:98.937% - 99.1%Cor e Forma:SolidPeso molecular:503.33yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Fórmula:C15H14O4Pureza:98.82% - 99.55%Cor e Forma:Pale Yellow PowderPeso molecular:258.27Olivetol
CAS:<p>Olivetol, found in lichens, is an organic antioxidant and THC synthesis precursor.</p>Fórmula:C11H16O2Pureza:99.98%Cor e Forma:(Melting Point 102-106°F) (Ntp 1992)Peso molecular:180.24ML-191
CAS:<p>ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.</p>Fórmula:C24H25N3O3Pureza:99.58%Cor e Forma:SolidPeso molecular:403.47Hemopressin (rat) acetate(568588-77-2 free base)
<p>Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.</p>Fórmula:C5H81N13O14Pureza:99.37%Cor e Forma:SolidPeso molecular:1148.31Org 27569
CAS:<p>Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and</p>Fórmula:C24H28ClN3OPureza:>99.99% - ≥95%Cor e Forma:SolidPeso molecular:409.95JD-5037
CAS:<p>JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.</p>Fórmula:C27H27Cl2N5O3SPureza:99.54% - 99.84%Cor e Forma:SolidPeso molecular:572.51PSB-SB-487
CAS:<p>PSB-SB-487 is antagonist of GPR55.</p>Fórmula:C26H32O4Pureza:98.53%Cor e Forma:SolidPeso molecular:408.53BML-190
CAS:<p>BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体，其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。</p>Fórmula:C23H23ClN2O4Pureza:97.70%Cor e Forma:SolidPeso molecular:426.89CID 16020046
CAS:<p>CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.</p>Fórmula:C25H19N3O4Pureza:99.03%Cor e Forma:SolidPeso molecular:425.44GW 405833
CAS:<p>GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selective</p>Fórmula:C23H24Cl2N2O3Pureza:99.82% - 99.93%Cor e Forma:SolidPeso molecular:447.35GW842166X
CAS:<p>GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.</p>Fórmula:C18H17Cl2F3N4O2Pureza:99.47%Cor e Forma:SolidPeso molecular:449.25RTICBM-189
CAS:<p>RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.</p>Fórmula:C15H14Cl2N2OPureza:99.96%Cor e Forma:SolidPeso molecular:309.19Bay 59-3074
CAS:<p>Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM).</p>Fórmula:C18H13F6NO4SPureza:97.68% - 99.69%Cor e Forma:SolidPeso molecular:453.36(±)-Ibipinabant
CAS:<p>(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.</p>Fórmula:C23H20Cl2N4O2SPureza:99.28% - 99.83%Cor e Forma:SolidPeso molecular:487.4N-Oleoyl glycine
CAS:<p>N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated Akt</p>Fórmula:C20H37NO3Pureza:97.43%Cor e Forma:SolidPeso molecular:339.51RVD-Hpα acetate(1193362-76-3 free base)
<p>RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.</p>Fórmula:C67H109N19O19Pureza:99.87%Cor e Forma:SolidPeso molecular:1484.71CB1/2 agonist 3
CAS:<p>CB1/2 agonist 3 is a competitive and potent CB1/CB2 agonist with high affinity for hCB1 and hCB2 and can be used to study neurological disorders.</p>Fórmula:C25H41NO2Pureza:98.78%Cor e Forma:SolidPeso molecular:387.6S-Methoprene
CAS:<p>S-Methoprene (ZR2458), a juvenile hormone analog, acts as an insecticide influencing redox activity and male sex differentiation.</p>Fórmula:C19H34O3Pureza:97.05% - 98.55%Cor e Forma:SolidPeso molecular:310.47Dehydroabiethylamine
CAS:<p>Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.</p>Fórmula:C20H31NPureza:98.79%Cor e Forma:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidPeso molecular:285.47AM404
CAS:<p>AM404 is a cannabinoid reuptake inhibitor and a TRPV (1) activator with neuroprotective and anticancer activities that blocks anandamide transport.</p>Fórmula:C26H37NO2Cor e Forma:SolidPeso molecular:395.58LEI-101
CAS:<p>LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.</p>Fórmula:C23H25FN4O4SPureza:98%Cor e Forma:SolidPeso molecular:472.53UCM 707
CAS:<p>endocannabinoid transport inhibitor</p>Fórmula:C25H37NO2Pureza:98%Cor e Forma:SolidPeso molecular:383.57CB1-IN-2
CAS:<p>CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.</p>Fórmula:C17H19Cl2N5OCor e Forma:SolidPeso molecular:380.27VSN-16
CAS:<p>VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.</p>Fórmula:C18H26N2O3Cor e Forma:SolidPeso molecular:318.41CB1R Allosteric modulator 4
CAS:<p>Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.</p>Fórmula:C20H17N3O2SCor e Forma:SolidPeso molecular:363.43UCM710
CAS:<p>UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).</p>Fórmula:C19H34O3Pureza:98%Cor e Forma:SolidPeso molecular:310.47CB1/2 agonist 4
CAS:<p>CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.</p>Fórmula:C27H45NO3Cor e Forma:SolidPeso molecular:431.65Palmitoyl serinol
CAS:<p>Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.</p>Fórmula:C19H39NO3Cor e Forma:SolidPeso molecular:329.52(R)-SLV 319
CAS:<p>(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.</p>Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4LH 21
CAS:<p>LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.</p>Fórmula:C20H20Cl3N3Cor e Forma:SolidPeso molecular:408.75NIDA 41020
CAS:<p>NIDA 41020 is a CB1 receptor antagonist.</p>Fórmula:C23H24Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:459.37AM-6538
CAS:<p>AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.</p>Fórmula:C26H25Cl2N5O4Cor e Forma:SolidPeso molecular:542.41CID1792197
CAS:<p>CID1792197 is a selective agonist of GPR55.</p>Fórmula:C24H23N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:481.59PM226
CAS:<p>CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.</p>Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49GPR55 agonist 3
CAS:<p>Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.</p>Fórmula:C19H16F4N4Cor e Forma:SolidPeso molecular:376.35
