Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 217 produtos de "Receptor de Canabinóides"
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Δ9-THCH
CAS:Δ9-THCH, a phytocannabinoid analytical reference standard, is present in a Cannabis variety cultivated for medicinal use. In the United States, it is classified as a Schedule I compound. This product is designated for research and forensic applications.Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49CB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Cor e Forma:Odour SolidCannabidivarinic acid
CAS:Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Fórmula:C20H26O4Cor e Forma:SolidPeso molecular:330.42Taranabant racemate
CAS:Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.Fórmula:C27H25ClF3N3O2Pureza:98%Cor e Forma:SolidPeso molecular:515.95Virodhamine
CAS:Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor.Fórmula:C22H37NO2Pureza:98%Cor e Forma:SoildPeso molecular:347.53WIN 55,212-2 Mesylate
CAS:WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) is a potent aminoalkylindole cannabinoid (CB) receptor agonist with Kis of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. Cannabinoid analogue WIN 55,212-2 Mesylate exhibited a novel anticancer effect against human tumors.Fórmula:C28H30N2O6SPureza:98% - 99.71%Cor e Forma:White To Off-White SolidPeso molecular:522.61AM251
CAS:AM251: potent CB1 blocker (IC50: 8 nM), 306x CB2 selective; GPR55 activator (EC50: 39 nM).Fórmula:C22H21Cl2IN4OPureza:97.43% - 98.79%Cor e Forma:A Crystalline SolidPeso molecular:555.24Hemopressin (human, mouse) acetate
Hemopressin: Nonapeptide, α1-hemoglobin derivative, CB1 inverse agonist, isolated from rats, oral, reduces inflammatory pain.Fórmula:C52H83N13O14Pureza:99.86%Cor e Forma:SolidPeso molecular:1114.29Cannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48Ref: TM-TN1465
1mg138,00€2mg203,00€5mg298,00€10mg449,00€25mg765,00€50mg1.054,00€100mg1.423,00€1mL*10mM (DMSO)306,00€PSB-SB-487
CAS:PSB-SB-487 is antagonist of GPR55.Fórmula:C26H32O4Pureza:98.53%Cor e Forma:SolidPeso molecular:408.53Ref: TM-T8975
1mg35,00€5mg80,00€10mg119,00€25mg231,00€50mg344,00€100mg480,00€200mg660,00€1mL*10mM (DMSO)87,00€ML-191
CAS:ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.Fórmula:C24H25N3O3Pureza:99.58%Cor e Forma:SolidPeso molecular:403.47ML-184
CAS:ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM.Fórmula:C25H34N4O3SPureza:99.45%Cor e Forma:SolidPeso molecular:470.63JD-5037
CAS:JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM.Fórmula:C27H27Cl2N5O3SPureza:99.54% - 99.84%Cor e Forma:SolidPeso molecular:572.51Ref: TM-T4453
1mg42,00€2mg55,00€5mg90,00€10mg133,00€25mg234,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)101,00€ML-193
CAS:ML-193: GPR55 antagonist, IC50 221nM, 27x selective over GPR35/CB1/CB2, may aid Parkinson's symptoms.Fórmula:C28H25N5O4SPureza:97.74%Cor e Forma:SolidPeso molecular:527.59Otenabant hydrochloride
CAS:Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM).Fórmula:C25H26Cl3N7OPureza:99.79% - ≥95%Cor e Forma:SolidPeso molecular:546.88Olivetol
CAS:Olivetol, found in lichens, is an organic antioxidant and THC synthesis precursor.Fórmula:C11H16O2Pureza:99.98%Cor e Forma:(Melting Point 102-106°F) (Ntp 1992)Peso molecular:180.24CB1 antagonist 4
CAS:TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.Fórmula:C30H25Cl2F3N4OSPureza:98.97%Cor e Forma:SolidPeso molecular:617.51Ref: TM-T8511
2mg46,00€5mg92,00€10mg152,00€25mg259,00€50mg405,00€100mg597,00€200mg848,00€1mL*10mM (DMSO)155,00€Bay 59-3074
CAS:Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM).
Fórmula:C18H13F6NO4SPureza:97.68% - 99.69%Cor e Forma:SolidPeso molecular:453.36AM1241
CAS:AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.Fórmula:C22H22IN3O3Pureza:98.937% - 99.1%Cor e Forma:SolidPeso molecular:503.33Ref: TM-T6755
2mg35,00€5mg49,00€10mg84,00€25mg168,00€50mg275,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)87,00€Org 27569
CAS:Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity andFórmula:C24H28ClN3OPureza:>99.99% - ≥95%Cor e Forma:SolidPeso molecular:409.95A-836339
CAS:A-836339: Potent cannabinoid, CB2-focused (Ki=0.64nM), lesser CB1 affinity (Ki=270nM); analgesic, anti-inflammatory in mice.Fórmula:C16H26N2O2SPureza:99.94%Cor e Forma:SolidPeso molecular:310.45Ref: TM-T7375
2mg34,00€5mg67,00€10mg109,00€25mg177,00€50mg260,00€100mg369,00€200mg500,00€1mL*10mM (DMSO)63,00€RTICBM-189
CAS:RTICBM-189 is a potent, brain-penetrant allosteric modulator of the cannabinoid type-1 (CB1) receptor with a pIC50 of 7.54 in Ca2+ mobilization assay.Fórmula:C15H14Cl2N2OPureza:99.96%Cor e Forma:SolidPeso molecular:309.19Ref: TM-T9466
2mg34,00€5mg52,00€10mg84,00€25mg161,00€50mg250,00€100mg369,00€200mg522,00€1mL*10mM (DMSO)67,00€GW842166X
CAS:GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.Fórmula:C18H17Cl2F3N4O2Pureza:99.47%Cor e Forma:SolidPeso molecular:449.25β-Caryophyllene
CAS:β-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist.Fórmula:C15H24Pureza:95.43% - 99.11%Cor e Forma:Turpentine (Ntp 1992)Peso molecular:204.35RVD-Hpα acetate(1193362-76-3 free base)
RVD-Hpα acetate is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.Fórmula:C67H109N19O19Pureza:99.87%Cor e Forma:SolidPeso molecular:1484.71Hemopressin (rat) acetate(568588-77-2 free base)
Hemopressin is a nonapeptide, CB2 agonist, derived from rat hemoglobin, with antinociceptive properties.Fórmula:C5H81N13O14Pureza:99.37%Cor e Forma:SolidPeso molecular:1148.31N-Oleoyl glycine
CAS:N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated AktFórmula:C20H37NO3Pureza:97.43%Cor e Forma:SolidPeso molecular:339.51ARN272
CAS:ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Fórmula:C27H20N4O2Pureza:98.23%Cor e Forma:SolidPeso molecular:432.47Voacamine
CAS:Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.
Fórmula:C43H52N4O5Pureza:98.54% - 99.82%Cor e Forma:SolidPeso molecular:704.9yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Cor e Forma:Pale Yellow PowderPeso molecular:258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€(±)-Ibipinabant
CAS:(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.Fórmula:C23H20Cl2N4O2SPureza:99.28% - 99.83%Cor e Forma:SolidPeso molecular:487.4GW 405833
CAS:GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selectiveFórmula:C23H24Cl2N2O3Pureza:99.82% - 99.93%Cor e Forma:SolidPeso molecular:447.35Linoleoyl Ethanolamide
CAS:Linoleoyl Ethanolamide is an endocannabinoid agent.Fórmula:C20H37NO2Pureza:99.97%Cor e Forma:SolidPeso molecular:323.51Ref: TM-T8425
1mg35,00€5mg67,00€10mg90,00€25mg164,00€50mg239,00€100mg348,00€200mg522,00€1mL*10mM (DMSO)85,00€AM281
CAS:AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.Fórmula:C21H19Cl2IN4O2Pureza:98.6% - >99.99%Cor e Forma:White To Off-White SolidPeso molecular:557.21Ref: TM-T2264
1mg80,00€5mg169,00€10mg259,00€25mg523,00€50mg750,00€100mg1.035,00€500mg2.062,00€1mL*10mM (DMSO)233,00€AM-2232
CAS:AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.43LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Fórmula:C22H27ClN6OPureza:98.45% - 99.51%Cor e Forma:SolidPeso molecular:426.94CID 16020046
CAS:CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.Fórmula:C25H19N3O4Pureza:99.03%Cor e Forma:SolidPeso molecular:425.44Otenabant
CAS:Otenabant (CP-945598) has been investigated for the treatment of Obesity.Fórmula:C25H25Cl2N7OPureza:99.43%Cor e Forma:SolidPeso molecular:510.42CB1-IN-1
CAS:CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.Fórmula:C33H31Cl2F3N6O3S2Pureza:99.08% - 99.76%Cor e Forma:SolidPeso molecular:751.67Ref: TM-T5996
1mg82,00€2mg110,00€5mg180,00€10mg258,00€25mg423,00€50mg588,00€100mg793,00€500mg1.594,00€1mL*10mM (DMSO)215,00€Tetrahydromagnolol
CAS:Tetrahydromagnolol can activate cannabinoid (CB) receptors.Fórmula:C18H22O2Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:270.37BML-190
CAS:BML-190 (Indomethacin morpholinylamide) 是一种 CB2 受体的配体，其对 CB2 受体 (Ki:435 nM) 和 CB1受体 (Ki> 2 μM)。Fórmula:C23H23ClN2O4Pureza:97.70%Cor e Forma:SolidPeso molecular:426.89CB1/2 agonist 3
CAS:CB1/2 agonist 3 is a competitive and potent CB1/CB2 agonist with high affinity for hCB1 and hCB2 and can be used to study neurological disorders.Fórmula:C25H41NO2Pureza:98.78%Cor e Forma:SolidPeso molecular:387.6S-Methoprene
CAS:S-Methoprene (ZR2458), a juvenile hormone analog, acts as an insecticide influencing redox activity and male sex differentiation.
Fórmula:C19H34O3Pureza:97.05% - 98.55%Cor e Forma:SolidPeso molecular:310.47Dehydroabiethylamine
CAS:Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.Fórmula:C20H31NPureza:98.79%Cor e Forma:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidPeso molecular:285.47PSB-KK1445
CAS:PSB-KK1445 is a potent and selective agonist of GPR18, exhibiting EC50 values of 45.4 nM for humans and 124 nM for mice. The selectivity of PSB-KK1445 for GPR18 over the CB receptor subtypes GPR55 and GPR183 exceeds 200-fold.Fórmula:C24H23FN6O2Peso molecular:446.48GPR55 agonist 3
CAS:Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.Fórmula:C19H16F4N4Cor e Forma:SolidPeso molecular:376.35PM226
CAS:CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49CID1792197
CAS:CID1792197 is a selective agonist of GPR55.Fórmula:C24H23N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:481.59VSN-16
CAS:VSN-16, a cannabinoid receptor agonist, is used potentially for the treatment of spasticity in multiple sclerosis.Fórmula:C18H26N2O3Cor e Forma:SolidPeso molecular:318.41GAT229
CAS:GAT229 is a CB1 positive modulator, enhancing CB agonist activity without direct activation; influences binding, signaling, and lowers ocular pressure in mice.Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39
