Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 196 produtos de "Receptor de Canabinóides"
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TC-C 14G
CAS:<p>CB1 receptor inverse agonist</p>Fórmula:C24H17Cl2F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:492.3ZCZ011
CAS:<p>ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.</p>Fórmula:C21H18N2O2SPureza:98%Cor e Forma:SolidPeso molecular:362.44(S)-SLV 319
CAS:<p>Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.</p>Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4COR167
CAS:<p>COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.</p>Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61CID1172084
CAS:<p>CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.</p>Fórmula:C23H18FN5O2S2Cor e Forma:SolidPeso molecular:479.55O-2093
CAS:<p>anandamide uptake inhibitor</p>Fórmula:C34H43Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:584.62GAT228
CAS:<p>GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].</p>Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39CB1 inverse agonist 2
CAS:<p>CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.</p>Fórmula:C24H20ClFN2OSCor e Forma:SolidPeso molecular:438.94CB2R agonist 1
CAS:<p>CB2R agonist 1 selectively binds human CB2R, EC50 of 0.56 µM, modulates inflammatory cytokines.</p>Fórmula:C22H32N2OCor e Forma:SolidPeso molecular:340.5LEI 101 hydrochloride
CAS:<p>LEI 101 hydrochloride is potent and selective CB2 partial agonist.</p>Fórmula:C23H26ClFN4O4SCor e Forma:SolidPeso molecular:508.99ANEB-001
CAS:<p>ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.</p>Fórmula:C22H24ClF3N2O2Cor e Forma:SolidPeso molecular:440.89CB1R Allosteric modulator 2
CAS:<p>Compound 18 is a potent CB1R allosteric modulator that acts as a negative modulator (NAM) for CB1R orthosteric ligands.</p>Fórmula:C19H15ClFN3OCor e Forma:SolidPeso molecular:355.79COR 170
CAS:<p>inverse agonist of CB2 receptors</p>Fórmula:C31H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:468.63CB1/2 agonist 2
CAS:<p>CB1/2 agonist 2 binds tightly to cannabinoid receptors, acting fully on CB1 and inversely on CB2.</p>Fórmula:C26H43NO3Cor e Forma:SolidPeso molecular:417.62PGN36
CAS:<p>PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).</p>Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43CB1R Allosteric modulator 1
CAS:<p>CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.</p>Fórmula:C24H24ClN3OCor e Forma:SolidPeso molecular:405.92S-777469
CAS:<p>S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.</p>Fórmula:C23H27FN2O4Cor e Forma:SolidPeso molecular:414.47CB2 receptor agonist 3
CAS:<p>GP 2A is a selective agonist of CB2 receptor.</p>Fórmula:C24H23Cl2N3OCor e Forma:SolidPeso molecular:440.36Virodhamine trifluoroacetate
CAS:<p>Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.</p>Fórmula:C24H38F3NO4Pureza:98%Cor e Forma:SolidPeso molecular:461.56LBP-1
CAS:<p>LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.</p>Fórmula:C23H29ClN6O3Cor e Forma:SolidPeso molecular:472.97MM-22
CAS:<p>biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamide</p>Fórmula:C36H60N4O5SPureza:98%Cor e Forma:SolidPeso molecular:660.95KLS-13019
CAS:<p>KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).</p>Fórmula:C22H29NO3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:355.47OMDM-6
CAS:<p>OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.</p>Fórmula:C28H42N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:454.64N-Arachidonyldopamine
CAS:<p>N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1</p>Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.63CB2 modulator 1
CAS:<p>CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.</p>Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36AM6545
CAS:<p>AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.</p>Fórmula:C26H23Cl2N5O3SPureza:97.03%Cor e Forma:SolidPeso molecular:556.46Arvanil
CAS:<p>Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.</p>Fórmula:C28H41NO3Pureza:99.49%Cor e Forma:SolidPeso molecular:439.63MJ 15
CAS:<p>MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.</p>Fórmula:C23H17Cl3N4OPureza:99.63%Cor e Forma:SolidPeso molecular:471.77AZD1940
CAS:<p>AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.</p>Fórmula:C20H29F2N3O2SPureza:98.68%Cor e Forma:SolidPeso molecular:413.52JTE-907
CAS:<p>JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。</p>Fórmula:C24H26N2O6Pureza:99.93%Cor e Forma:SolidPeso molecular:438.47CB1 agonist 1
CAS:<p>CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.</p>Fórmula:C24H24N2O5SPureza:98.56%Cor e Forma:SolidPeso molecular:452.52SCH-336
CAS:<p>SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.</p>Fórmula:C23H25NO8S3Pureza:95.01%Cor e Forma:SolidPeso molecular:539.64Olorinab
CAS:<p>Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.</p>Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:SolidPeso molecular:357.41SR144528
CAS:<p>SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).</p>Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05PSB-CB5
CAS:<p>PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Fórmula:C20H17ClN2O2SPureza:99.26%Cor e Forma:SolidPeso molecular:384.88CB2R PAM
CAS:<p>CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.</p>Fórmula:C21H24BrFN2O2Pureza:99.09%Cor e Forma:SolidPeso molecular:435.33AM-1235
CAS:<p>AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.</p>Fórmula:C24H21FN2O3Pureza:97.77%Cor e Forma:SolidPeso molecular:404.43CB1R antagonist 1
CAS:<p>CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.</p>Fórmula:C18H23F3N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:404.45Nonabine
CAS:<p>Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.</p>Fórmula:C25H33NO2Pureza:99.46% - 99.95%Cor e Forma:SolidPeso molecular:379.54CAY10508
CAS:<p>CAY10508 is a potent and selective inverse agonist for the central cannabinoid (CB1) receptor with therapeutic potential for treating obesity and drug dependence, lacking psychotropic effects. It exhibits a Ki value of 243 nM and an EC50 of 195 nM. At a concentration of 10 µM, CAY10508 displaces [3H]-CP-55,940 with 100% efficacy at the CB1 receptor and 35% at the peripheral cannabinoid (CB2) receptor. Its inverse agonist activity at the CB1 receptor was confirmed through a [35S]-GTPγS binding assay.</p>Fórmula:C21H14Br2N2O2Cor e Forma:SolidPeso molecular:486.2PF-03550096
CAS:<p>PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1].</p>Fórmula:C19H28N4O4Cor e Forma:SolidPeso molecular:376.45COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Cor e Forma:SolidPeso molecular:337.82CB1 antagonist 1
CAS:<p>CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and</p>Fórmula:C26H22Cl2N4Pureza:98%Cor e Forma:SolidPeso molecular:461.39Heptadecanoyl ethanolamide
CAS:<p>Heptadecanoyl ethanolamide, an endogenous cannabinoid, serves as a synthetic analog of PEA, featuring an odd-numbered (17-carbon) fatty acid chain [1].</p>Fórmula:C19H39NO2Cor e Forma:SolidPeso molecular:313.52AM841
CAS:<p>AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.</p>Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66(R)-Monlunabant
CAS:<p>(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].</p>Fórmula:C26H22ClF3N6O3SPureza:98%Cor e Forma:SolidPeso molecular:591GSK-554418A
CAS:<p>GSK-554418A, a novel azaindole CB(2) agonists, is used for the treatment of chronic pain. It is efficacious in the acute model and the chronic joint pain model.</p>Fórmula:C19H19ClN4O2Cor e Forma:SolidPeso molecular:370.83CB 65
CAS:<p>CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.</p>Fórmula:C22H28ClN3O3Pureza:98.73%Cor e Forma:SolidPeso molecular:417.93O-Arachidonoyl glycidol
CAS:<p>O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].</p>Fórmula:C23H36O3Cor e Forma:SolidPeso molecular:360.53OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:SolidPeso molecular:432.64
