Receptor de Canabinóides
Os receptores de canabinoides são GPCRs que mediam os efeitos dos canabinoides endógenos (endocanabinoides) e dos fitocanabinoides, como aqueles encontrados na cannabis. Os dois principais tipos de receptores de canabinoides, CB1 e CB2, estão envolvidos na regulação de uma ampla gama de processos fisiológicos, incluindo percepção da dor, apetite, humor e função imunológica. Moduladores de receptores de canabinoides têm potencial terapêutico no tratamento de condições como dor crônica, epilepsia e esclerose múltipla. Na CymitQuimica, oferecemos uma ampla gama de moduladores de receptores de canabinoides de alta qualidade para apoiar sua pesquisa em neurofarmacologia, manejo da dor e imunologia.
Foram encontrados 217 produtos de "Receptor de Canabinóides"
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ANEB-001
CAS:ANEB-001 is an orally active CB1 inhibitor that can be used in studies of acute cannabinoid intoxication.Fórmula:C22H24ClF3N2O2Cor e Forma:SolidPeso molecular:440.89CB1R Allosteric modulator 4
CAS:Modulates CB1R positively; inhibits cAMP production; strong β-arrestin-2 recruitment.Fórmula:C20H17N3O2SCor e Forma:SolidPeso molecular:363.43PGN36
CAS:PGN36 (Compound 18) is a potent CB2 receptor antagonist with a high affinity (Ki=0.09 μM).Fórmula:C21H23N3O3Cor e Forma:SolidPeso molecular:365.43CB1R Allosteric modulator 2
CAS:Compound 18 is a potent CB1R allosteric modulator that acts as a negative modulator (NAM) for CB1R orthosteric ligands.Fórmula:C19H15ClFN3OCor e Forma:SolidPeso molecular:355.79GAT229
CAS:GAT229 is a CB1 positive modulator, enhancing CB agonist activity without direct activation; influences binding, signaling, and lowers ocular pressure in mice.Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39CB1-IN-2
CAS:CB1-IN-2 (4g) inhibits CB1 receptor with 0.644 μM IC50; crosses blood-brain barrier, may cause CNS side effects like Rimonabant.Fórmula:C17H19Cl2N5OCor e Forma:SolidPeso molecular:380.27COR167
CAS:COR167 is a CB2 agonist with immunomodulatory effects, protective brain properties, and antinociception.Fórmula:C28H38N2O2Cor e Forma:SolidPeso molecular:434.61UCM 707
CAS:endocannabinoid transport inhibitorFórmula:C25H37NO2Pureza:98%Cor e Forma:SolidPeso molecular:383.57SMM-189
CAS:SMM-189 is a potent and selective CB2 inverse agonist.Fórmula:C19H12Cl2O3Cor e Forma:SolidPeso molecular:359.2CAY10412
CAS:Anandamide (AEA) is an endocannabinoid with neural reuptake. CAY10412, an AEA analog, inhibits this reuptake without binding to CB receptors.Fórmula:C25H36O2SCor e Forma:SolidPeso molecular:400.62(S)-SLV 319
CAS:Ibipinabant (SLV319), a potent CB1 antagonist, K i = 7.8 nM, >1000x selective over CB2, for obesity and diabetic research.Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4LEI-101
CAS:LEI-101: potent CB2 agonist, pEC50=8, bioavailable, >100x selective over CB1, potential for inflammatory diseases.Fórmula:C23H25FN4O4SPureza:98%Cor e Forma:SolidPeso molecular:472.53Palmitoyl serinol
CAS:Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.Fórmula:C19H39NO3Cor e Forma:SolidPeso molecular:329.52ZCZ011
CAS:ZCZ011 enhances CB1 receptor effects, crosses blood-brain barrier, and potentiates cannabimimetic behaviors in mice.Fórmula:C21H18N2O2SPureza:98%Cor e Forma:SolidPeso molecular:362.44KLS-13019
CAS:KLS-13019 is a highly effective and orally active GPR55 receptor antagonist, neuroprotective can reverse chemotherapy-induced peripheral neuropathy (CIPN).Fórmula:C22H29NO3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:355.47Virodhamine trifluoroacetate
CAS:Virodhamine trifluoroacetate: full GPR55 & CB2 agonist, partial CB1 antagonist, cannabinoid receptor mixed antagonist.Fórmula:C24H38F3NO4Pureza:98%Cor e Forma:SolidPeso molecular:461.56OMDM-6
CAS:OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.Fórmula:C28H42N2O3Pureza:99.66%Cor e Forma:SolidPeso molecular:454.64Ref: TM-T12307
1mg85,00€5mg170,00€10mg250,00€25mg371,00€50mg522,00€100mg712,00€200mg954,00€1mL*10mM (DMSO)187,00€LBP-1
CAS:LBP-1 is a cannabinoid receptor type 1 (CB1) agonist.Fórmula:C23H29ClN6O3Cor e Forma:SolidPeso molecular:472.97N-Arachidonyldopamine
CAS:N-Arachidonyldopamine (NADA) is a selective and potent endogenous CB1 receptor agonist (Ki: 250 nM).N-Arachidonyldopamine is also a potent and selective TRPV1Fórmula:C28H41NO3Pureza:97.65%Cor e Forma:SolidPeso molecular:439.632-Arachidonoylglycerol
CAS:In the central nervous system, 2-Arachidonoylglycerol is a second endogenous cannabinoid ligandFórmula:C23H38O4Pureza:95%Cor e Forma:LiquidPeso molecular:378.55GPR55 agonist 3
CAS:Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55.Fórmula:C19H16F4N4Cor e Forma:SolidPeso molecular:376.35AM404
CAS:AM404 is a cannabinoid reuptake inhibitor and a TRPV (1) activator with neuroprotective and anticancer activities that blocks anandamide transport.Fórmula:C26H37NO2Cor e Forma:SolidPeso molecular:395.58CB2 modulator 1
CAS:CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.Fórmula:C18H19F3N4O2Pureza:99.6%Cor e Forma:SolidPeso molecular:380.36MJ 15
CAS:MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.Fórmula:C23H17Cl3N4OPureza:99.63%Cor e Forma:SolidPeso molecular:471.77CB1/2 agonist 4
CAS:CB1/2 agonist 4 is a potent CB1 full agonist (EC50: 15.09 nM) and CB2 partial agonist (EC50: 1.16 nM), with anti-pain and TRPV1 activation properties.Fórmula:C27H45NO3Cor e Forma:SolidPeso molecular:431.65CB1R Allosteric modulator 1
CAS:CB1R modulator 1 (compound 11), a potent CB1R inhibitor, decreases activity of orthosteric ligands.Fórmula:C24H24ClN3OCor e Forma:SolidPeso molecular:405.92UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Fórmula:C19H34O3Pureza:98%Cor e Forma:SolidPeso molecular:310.47MM-22
CAS:biotinylated anandamide analog acts as a probe for visualizing the accumulation and intracellular trafficking of anandamideFórmula:C36H60N4O5SPureza:98%Cor e Forma:SolidPeso molecular:660.95CB2R agonist 1
CAS:CB2R agonist 1 selectively binds human CB2R, EC50 of 0.56 µM, modulates inflammatory cytokines.Fórmula:C22H32N2OCor e Forma:SolidPeso molecular:340.5S-777469
CAS:S-777469: Selective CB2 agonist, oral, inhibits itching in mice (Ki: 36 nM). Anti-pruritic.Fórmula:C23H27FN2O4Cor e Forma:SolidPeso molecular:414.47PM226
CAS:CB2 agonist with Ki of 12.8 nM; EC50 of 38.67 nM. Negligible CB1 affinity, no GPR55 activity. Anti-inflammatory, neuroprotective, crosses BBB.Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49AZD-2207
CAS:AZD-2207 is a cannabinoid receptor CB1 antagonist and highly lipophilic compound for the treatment of type 2 diabetes mellitus and obesity.Fórmula:C25H25Cl2F3N4O4SCor e Forma:SolidPeso molecular:605.46Cannabicitran
CAS:Cannabicitran is a cannabinoid that can decrease rabbits intraocular pressure [1] [2].Fórmula:C21H30O2Cor e Forma:SolidPeso molecular:314.46CB1 inverse agonist 2
CAS:CB1 inverse agonist 2, an oral drug, counters CB1 effects, reducing CP55940-induced hypothermia and anorexia in mice.Fórmula:C24H20ClFN2OSCor e Forma:SolidPeso molecular:438.94GAT228
CAS:GAT228, an allosteric ligand for the cannabinoid receptor 1 (CB1), functions as the enantiomer of GAT211 [1].Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39AM-6538
CAS:AM6538: long-acting, high-affinity CB antagonist similar to rimonabant, useful for studying cannabinoid agonists.Fórmula:C26H25Cl2N5O4Cor e Forma:SolidPeso molecular:542.41COR 170
CAS:inverse agonist of CB2 receptorsFórmula:C31H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:468.63NIDA 41020
CAS:NIDA 41020 is a CB1 receptor antagonist.Fórmula:C23H24Cl2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:459.37LH 21
CAS:LH-21, a strong CB1 receptor antagonist, curbs eating and lessens weight gain in obese rats.Fórmula:C20H20Cl3N3Cor e Forma:SolidPeso molecular:408.75CID1792197
CAS:CID1792197 is a selective agonist of GPR55.Fórmula:C24H23N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:481.59O-2093
CAS:anandamide uptake inhibitorFórmula:C34H43Cl2NO3Pureza:98%Cor e Forma:SolidPeso molecular:584.62CID1172084
CAS:CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.Fórmula:C23H18FN5O2S2Cor e Forma:SolidPeso molecular:479.55CB2 receptor agonist 3
CAS:GP 2A is a selective agonist of CB2 receptor.Fórmula:C24H23Cl2N3OCor e Forma:SolidPeso molecular:440.36TC-C 14G
CAS:CB1 receptor inverse agonistFórmula:C24H17Cl2F2NO4Pureza:98%Cor e Forma:SolidPeso molecular:492.3(R)-SLV 319
CAS:(R)-SLV 319: potent CB1 antagonist, K i of 894 nM, dextrorotatory isomer.Fórmula:C23H20Cl2N4O2SCor e Forma:SolidPeso molecular:487.4Olorinab
CAS:Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:SolidPeso molecular:357.41CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Fórmula:C24H24N2O5SPureza:98.56%Cor e Forma:SolidPeso molecular:452.52SR144528
CAS:SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Fórmula:C25H33NO2Pureza:99.82% - 99.94%Cor e Forma:SolidPeso molecular:379.54CB1R antagonist 1
CAS:CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.Fórmula:C18H23F3N2O3SPureza:99.65%Cor e Forma:SolidPeso molecular:404.45
