
Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 793 produtos de "Síntese de DNA/RNA"
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Thio-ITP
CAS:Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I & II with Ki of 40.9 & 38.0 μM.Fórmula:C10H15N4O13P3SCor e Forma:SolidPeso molecular:524.235'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Cor e Forma:SolidPeso molecular:687.74ART899
CAS:ART899, a derivative of ART558, is a potent and specific conformational inhibitor of DNA polymerase θ (Polθ). It specifically inhibits the MMEJ activity of Polθ with an IC50 of 180 nM. Additionally, ART899 selectively enhances the radiosensitivity of tumor cells and possesses a strong independent antitumor effect on cancer cells.Fórmula:C19H16ClF4N3O4Cor e Forma:SolidPeso molecular:464.81AF-615
CAS:AF-615 is an innovative inhibitor of the CDT1/Geminin protein complex, capable of inducing DNA damage and cell death in cancer cells.Fórmula:C10H13N5O2SCor e Forma:SolidPeso molecular:267.315'-O-DMT-N4-Bz-2'-F-dC
CAS:5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.Fórmula:C37H34FN3O7Cor e Forma:SolidPeso molecular:651.68Ac-dA Phosphoramidite
CAS:Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.Fórmula:C42H50N7O7PCor e Forma:SolidPeso molecular:795.8785-Iminodaunorubicin
CAS:5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Fórmula:C27H30N2O9Cor e Forma:SolidPeso molecular:526.54M7G(3'-OMe-5')pppA(2'-OMe)
M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.Fórmula:C23H33N10O17P3Cor e Forma:SolidPeso molecular:814.495-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.Fórmula:C22H31N3O5SiCor e Forma:SolidPeso molecular:445.58Emicoron
CAS:Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Fórmula:C52H58N6O4Pureza:98%Cor e Forma:SolidPeso molecular:831.05RAD51-IN-3
CAS:RAD51-IN-3 is a Rad51 inhibitor.Fórmula:C31H41N5O5S2Cor e Forma:SolidPeso molecular:627.82LB80317
CAS:LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.Fórmula:C10H14N5O5PCor e Forma:SolidPeso molecular:315.22Bisucaberin
CAS:Bisucaberin: a siderophore with anticancer properties; inhibits L1210/1MC cells and enhances 1023 cell cytolysis.Fórmula:C18H32N4O6Cor e Forma:SolidPeso molecular:400.476TAC
CAS:TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokinesFórmula:C14H12ClF2NO2SPureza:99.20%Cor e Forma:SolidPeso molecular:331.77Remdesivir nucleoside monophosphate
CAS:Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.Fórmula:C12H14N5O7PCor e Forma:SolidPeso molecular:371.24R-1479
CAS:R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.Fórmula:C9H12N6O5Pureza:98.11% - 99.95%Cor e Forma:SolidPeso molecular:284.23RNA splicing modulator 2
CAS:RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48dUTP trisodium
CAS:<p>dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.</p>Fórmula:C9H12N2Na3O14P3Pureza:100.00%Cor e Forma:SolidPeso molecular:534.09Orotidine 5′-monophosphate trisodium
CAS:Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.Fórmula:C10H10N2Na3O11PCor e Forma:SolidPeso molecular:434.14m7Gpppm6AmpG
CAS:m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].Fórmula:C33H45N15O24P4Cor e Forma:SolidPeso molecular:1159.69

