Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 793 produtos de "Síntese de DNA/RNA"
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Cidofovir dihydrate
CAS:Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Fórmula:C8H18N3O8PPureza:99.44%Cor e Forma:SolidPeso molecular:315.22Fidaxomicin
CAS:Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.Fórmula:C52H74Cl2O18Pureza:99.76% - 99.82%Cor e Forma:SolidPeso molecular:1058.04AT-130
CAS:<p>AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.</p>Fórmula:C22H22BrN3O5Pureza:97.81%Cor e Forma:SolidPeso molecular:488.33Aplidine
CAS:Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM).Fórmula:C57H87N7O15Pureza:99.86%Cor e Forma:SolidPeso molecular:1110.34Datelliptium chloride hydrochloride
CAS:<p>Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities.</p>Fórmula:C23H29Cl2N3OPureza:99.46%Cor e Forma:SolidPeso molecular:434.4IMT1B
CAS:<p>IMT1B (LDC203974) is an oral POLRMT inhibitor that curbs mtDNA expression and has anti-cancer properties.</p>Fórmula:C24H21ClFNO6Pureza:98.26% - 99.83%Cor e Forma:SolidPeso molecular:473.88NSC 617145
CAS:NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependentFórmula:C13H10Cl4N2O4Pureza:99.78%Cor e Forma:SolidPeso molecular:400.04GS-441524 HCl
CAS:GS-441524: Inhibits FIP virus, EC50 at 0.78 μM, precursor to active triphosphate, non-toxic up to 100 μM, works at ≥1 μM, metabolite of Remdesivir.Fórmula:C12H14ClN5O4Cor e Forma:SolidPeso molecular:327.72Garenoxacin mesylate hydrate
CAS:Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strainsFórmula:C23H20F2N2O4·CH4O3S·H2OPureza:99.56%Cor e Forma:SolidPeso molecular:540.53Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Cor e Forma:SolidPeso molecular:487.446-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Cor e Forma:SolidPeso molecular:283.31Nemorubicin
CAS:<p>Nemorubicin (PNU 152243) is a unique doxorubicin variant with varied antitumor action, metabolism, and toxicity, effective against resistant tumors.</p>Fórmula:C32H37NO13Pureza:97.4%Cor e Forma:SolidPeso molecular:643.64Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFórmula:C24H26N4O5SPureza:99.00% - 99.86%Cor e Forma:SolidPeso molecular:482.55Levofloxacin
CAS:Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.Fórmula:C18H20FN3O4Pureza:98.14% - 99.80%Cor e Forma:Off-White To Yellow CrystalsPeso molecular:361.37Gadodiamide
CAS:Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.Fórmula:C16H26GdN5O8Pureza:99.86% - 99.93%Cor e Forma:SolidPeso molecular:573.66AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Fórmula:C21H17N3O2Pureza:99.19%Cor e Forma:SolidPeso molecular:343.38CB-6644
CAS:CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.Fórmula:C29H34ClFN4O5Pureza:96.33% - 99.85%Cor e Forma:SolidPeso molecular:573.06Acelarin
CAS:<p>Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.</p>Fórmula:C25H27F2N4O8PPureza:99.26%Cor e Forma:SolidPeso molecular:580.47ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Fórmula:C15H9F4N5OSPureza:98.12%Cor e Forma:SolidPeso molecular:383.32FUBP1-IN-1
CAS:FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.Fórmula:C19H14F3N3O2SPureza:99.7%Cor e Forma:SolidPeso molecular:405.39
