HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 447 produtos de "HIV Protease"
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Betulin diacetate
CAS:<p>Betulin diacetate is a bioactive chemical.</p>Fórmula:C34H54O4Cor e Forma:SolidPeso molecular:526.8Saquinavir mesylate
CAS:<p>Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy</p>Fórmula:C39H54N6O8SPureza:99.19%Cor e Forma:White Or Pale Yellow PowderPeso molecular:766.9Ditiocarb sodium
CAS:<p>Ditiocarb sodium (Sodium diethyldithiocarbamate) (sodium diethiocarbamate) is a copper reagent, which reacts with Cu2 + solution to form a complex and improves</p>Fórmula:C5H10NNaS2Pureza:98.04%Cor e Forma:White Solid CrystallinePeso molecular:171.26Delavirdine mesylate
CAS:<p>Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).</p>Fórmula:C23H32N6O6S2Pureza:99.99%Cor e Forma:Light Brown SolidPeso molecular:552.67Dolutegravir sodium
CAS:<p>Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature</p>Fórmula:C20H18F2N3NaO5Pureza:98% - 99.46%Cor e Forma:SolidPeso molecular:441.36Tenofovir alafenamide
CAS:<p>Tenofovir alafenamide (GS-7340) is a nucleotide reverse transcriptase inhibitor (NRTI) and a novel ester prodrug of the antiretroviral tenofovir.</p>Fórmula:C21H29N6O5PPureza:99.68% - 99.81%Cor e Forma:SolidPeso molecular:476.47Amprenavir
CAS:<p>Amprenavir (KVX-478) is a synthetic derivative of hydroxyethylamine sulfonamide that selectively binds to and inhibits human immunodeficiency virus (HIV)</p>Fórmula:C25H35N3O6SPureza:99.60% - 99.87%Cor e Forma:Off-White To Pale YellowPeso molecular:505.63Cobicistat
CAS:<p>Cobicistat (GS-9350): A carbamate, thiazole derivative, and CYP3A inhibitor used to boost anti-HIV drugs for treating HIV.</p>Fórmula:C40H53N7O5S2Pureza:97.36% - 99.62%Cor e Forma:SolidPeso molecular:776.02Escin IA
CAS:<p>Escin IA (Escin IA;Aescin IA) is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM.</p>Fórmula:C55H86O24Pureza:98.97% - 99.81%Cor e Forma:SolidPeso molecular:1131.26Dolutegravir
CAS:<p>Dolutegravir (GSK1349572), HIV integrase inhibitor with IC50 of 2.7 nM, partly effective against some raltegravir-resistant HIV strains.</p>Fórmula:C20H19F2N3O5Pureza:98.97% - 99.75%Cor e Forma:White To Pale Yellow SolidPeso molecular:419.38Lopinavir
CAS:<p>Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation.</p>Fórmula:C37H48N4O5Pureza:98% - 99.62%Cor e Forma:White Crystalline SolidPeso molecular:628.8Raltegravir sodium
CAS:<p>Raltegravir (MK 0518) sodium is a potent, orally active HIV integrase (IN) inhibitor.</p>Fórmula:C20H20FN6NaO5Cor e Forma:SolidPeso molecular:466.405Doravirine
CAS:<p>Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor, used in the treatment of HIV/AIDS.</p>Fórmula:C17H11ClF3N5O3Pureza:99.65% - 99.79%Cor e Forma:SolidPeso molecular:425.75Ganoderic acid B
CAS:<p>Ganoderic acid B: quality marker for G. lucidum products, inhibits telomerase & EBV activation, moderates HIV-1 protease.</p>Fórmula:C30H44O7Pureza:99.09% - 99.95%Cor e Forma:SolidPeso molecular:516.67Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Fórmula:C10H12N4O3Pureza:99.64%Cor e Forma:White Crystalline PowderPeso molecular:236.23Temsavir
CAS:<p>Temsavir (BMS626529) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells.</p>Fórmula:C24H23N7O4Pureza:99.14%Cor e Forma:SolidPeso molecular:473.48Darunavir
CAS:<p>Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Fórmula:C27H37N3O7SPureza:99.67% - 99.76%Cor e Forma:White Amorphous SolidPeso molecular:547.66BMS-707035
CAS:<p>BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.</p>Fórmula:C17H19FN4O5SPureza:99.78%Cor e Forma:SolidPeso molecular:410.42Raltegravir
CAS:<p>Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV</p>Fórmula:C20H21FN6O5Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:444.42TAT
CAS:<p>TAT peptide (YGRKKRRQRRR), originating from the human immunodeficiency virus-1 (HIV-1) transactivator of transcription (TAT), enhances the solubility and</p>Fórmula:C64H118N32O14Pureza:>99.99%Cor e Forma:SolidPeso molecular:1559.83Amylmetacresol
CAS:<p>Amylmetacresol treats sore throat, pharyngitis, tonsillitis, laryngitis, influenza A, and SARS-CoV.</p>Fórmula:C12H18OPureza:99.66%Cor e Forma:SolidPeso molecular:178.27Elvitegravir
CAS:<p>Elvitegravir (JTK-303) is an HIV integrase inhibitor and CYP2C9 inducer.</p>Fórmula:C23H23ClFNO5Pureza:98.43% - 99.57%Cor e Forma:SolidPeso molecular:447.88Vesnarinone
CAS:<p>Vesnarinone (Arkin) (INN) is a mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but</p>Fórmula:C22H25N3O4Pureza:96.69% - 98.13%Cor e Forma:SolidPeso molecular:395.45I-XW-053 sodium
CAS:<p>I-XW-053 sodium inhibits the replication of a diverse panel of primary HIV-1 isolates in Peripheral blood mononuclear cell with no appreciable cytotoxicity.</p>Fórmula:C22H16N2NaO2Cor e Forma:SolidPeso molecular:363.3722,4-Dihydroxypyridine
CAS:<p>2,4-Dihydroxypyridine: a pyridine derivative, chelates metals, assesses ion levels, measures enzymatic reactions, and quantifies biomolecules.</p>Fórmula:C5H5NO2Pureza:97.79%Cor e Forma:White To Yellow-Beige Crystals OrPeso molecular:111.1PTACH
CAS:<p>PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM).</p>Fórmula:C20H26N2O2S2Pureza:87.44% - 99.74%Cor e Forma:SolidPeso molecular:390.56Darunavir Ethanolate
CAS:<p>Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Fórmula:C29H43N3O8SPureza:99.84% - 99.86%Cor e Forma:SolidPeso molecular:593.74LDC4297 hydrochloride
CAS:<p>LDC4297 hydrochloride is a selective and potent CDK7 inhibitor with broad-spectrum antiviral activity, useful for research on viral infections.</p>Fórmula:C23H29ClN8OCor e Forma:SolidPeso molecular:468.98Thiamine disulfide
CAS:<p>Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.</p>Fórmula:C24H34N8O4S2Pureza:99.81%Cor e Forma:CoaPeso molecular:562.71Inosine pranobex
CAS:<p>Inosine pranobex (Delimmun) has a lot of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions.</p>Fórmula:C52H78N10O17Pureza:99.78% - 99.91%Cor e Forma:SolidPeso molecular:1115.23Raltegravir potassium
CAS:<p>Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.</p>Fórmula:C20H20FN6O5·KPureza:98% - 99.55%Cor e Forma:Off-White SolidPeso molecular:482.51Tenofovir alafenamide hemifumarate
CAS:<p>Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.</p>Fórmula:C21H29N6O5PC4H4O4Pureza:99.33% - 99.96%Cor e Forma:SolidPeso molecular:534.51Rolipram
CAS:<p>Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.</p>Fórmula:C16H21NO3Pureza:99.22% - >99.99%Cor e Forma:SolidPeso molecular:275.34PMEDAP
CAS:<p>PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency</p>Fórmula:C8H13N6O4PPureza:99.77%Cor e Forma:SolidPeso molecular:288.2Dimercaprol
CAS:<p>Dimercaprol (Dicaptol) is an anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-</p>Fórmula:C3H8OS2Pureza:98.91% - 99.64%Cor e Forma:Viscous Oily LiquidPeso molecular:124.22Peldesine dihydrochloride
CAS:<p>Peldesine (BCX 34) dihydrochloride is an inhibitor of PNP in humans, rats, and mice, also hindering T-cell proliferation, used in lymphoma and HIV research.</p>Fórmula:C12H13Cl2N5OCor e Forma:SolidPeso molecular:314.17IMB-301
CAS:<p>IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.</p>Fórmula:C19H17Cl2FN2OPureza:99.72%Cor e Forma:SolidPeso molecular:379.26Fostemsavir
CAS:<p>Fostemsavir (BMS-663068) is an HIV-1 attachment inhibitor in development for the treatment of HIV-1 infection.</p>Fórmula:C25H26N7O8PPureza:98.95%Cor e Forma:SolidPeso molecular:583.49HODHBt
CAS:<p>HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.</p>Fórmula:C7H5N3O2Pureza:99.45% - 99.95%Cor e Forma:Off-White To Yellow SolidPeso molecular:163.13Rilpivirine
CAS:<p>Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment</p>Fórmula:C22H18N6Pureza:97.22% - 98.83%Cor e Forma:SolidPeso molecular:366.42NBD-557
CAS:<p>NBD-557 is a potentially HIV-1 inhibitor.</p>Fórmula:C17H24BrN3O2Pureza:99.52%Cor e Forma:SolidPeso molecular:382.3Des(benzylpyridyl) Atazanavi
CAS:<p>The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.</p>Fórmula:C26H43N5O7Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:537.65Saquinavir
CAS:<p>Saquinavir (Ro 31-8959) is a potent HIV protease inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.</p>Fórmula:C38H50N6O5Pureza:99.50% - >99.99%Cor e Forma:SolidPeso molecular:670.84Dexelvucitabine
CAS:<p>Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C9H10FN3O3Pureza:98.25%Cor e Forma:SolidPeso molecular:227.19HIV-1 Nef-IN-1
CAS:<p>HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).</p>Fórmula:C18H16O2Pureza:99.90%Cor e Forma:SolidPeso molecular:264.32Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Fórmula:C20H15BrN6OPureza:97.61% - 99.74%Cor e Forma:White To Off-White SolidPeso molecular:435.284-Chloro-2-(trifluoroacetyl)aniline hydrochloride
CAS:<p>4-Chloro-2-(trifluoroacetyl)aniline hydrochloride is an inhibitor of HIV-1 RT (HIV reverse transcriptase) .</p>Fórmula:C8H6Cl2F3NOPureza:97.15%Cor e Forma:SolidPeso molecular:260.04Obefazimod
CAS:<p>Obefazimod (ABX-464) is a potent anti-HIV agent. ABX464 inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs).</p>Fórmula:C16H10ClF3N2OPureza:99.86%Cor e Forma:SolidPeso molecular:338.71RN-18
CAS:<p>RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells).</p>Fórmula:C20H16N2O4SPureza:97.21% - 98.39%Cor e Forma:SolidPeso molecular:380.42Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Fórmula:C21H23N5O3SPureza:98.03% - ≥95%Cor e Forma:SolidPeso molecular:425.5
