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HIV Protease

HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 447 produtos de "HIV Protease"

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  • HIV-1 inhibitor-31

    CAS:
    <p>HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.</p>
    Fórmula:C21H13Cl2N3O2
    Cor e Forma:Solid
    Peso molecular:410.25
  • Deaminase inhibitor-1

    CAS:
    <p>Deaminase inhibitor-1 is an APOBEC3G DNA Deaminase inhibitor with an IC 50 value of 18.9 μM [1].</p>
    Fórmula:C11H12BrN3OS
    Cor e Forma:Solid
    Peso molecular:314.2
  • HIV-1 inhibitor-50

    CAS:
    <p>HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM).</p>
    Fórmula:C24H18FN5O2
    Cor e Forma:Solid
    Peso molecular:427.43
  • S-1360

    CAS:
    <p>S-1360 is an inhibitor of HIV-1 integrase.</p>
    Fórmula:C16H12FN3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:313.28
  • PF-46396

    CAS:
    <p>PF-46396 is a HIV maturation inhibitor and can be used against HIV-1 clade B and C.</p>
    Fórmula:C27H29F3N2O
    Cor e Forma:Solid
    Peso molecular:454.53
  • HIV-1 inhibitor-39

    CAS:
    <p>HIV-1 inhibitor-39: blocks HIV-1, anti-RT (IC50=15.75 μM), toxic to MT-4 cells (CC50=112.9 μM).</p>
    Fórmula:C20H17ClN4O4S4
    Cor e Forma:Solid
    Peso molecular:541.09
  • HIV-1 inhibitor-48

    CAS:
    <p>HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity .</p>
    Fórmula:C19H16BrN5
    Cor e Forma:Solid
    Peso molecular:394.27
  • HIV-1 inhibitor-35

    CAS:
    <p>HIV-1 inhibitor-35, potent against HIV (EC50: 80 nM LTR, 70 nM CMV), also suppresses HepG2 cells (CC50: 40 nM), may reverse HIV-1 latency.</p>
    Fórmula:C13H12Cl3N5OS
    Cor e Forma:Solid
    Peso molecular:392.69
  • HIV-1 inhibitor-9

    CAS:
    <p>HIV-1 inhibitor-9 potently blocks WT and NNRTI-resistant HIV strains at low nanomolar levels.</p>
    Fórmula:C24H21N5O
    Cor e Forma:Solid
    Peso molecular:395.46
  • HIV-1 inhibitor-56

    CAS:
    <p>HIV-1 inhibitor-56 (compound 12126065) is a potent non-nucleoside reverse transcriptase inhibitor with significant antiviral activity against wild-type HIV-1,</p>
    Fórmula:C22H14ClN7O2S
    Cor e Forma:Solid
    Peso molecular:475.91
  • Cgp 53820

    CAS:
    <p>CGP 53820 is a pseudosymmetric inhibitor of HIV-1 Protease.</p>
    Fórmula:C31H51N5O5
    Cor e Forma:Solid
    Peso molecular:573.77
  • HIV-1 inhibitor-33

    CAS:
    <p>HIV-1 inhibitor-33, potent against HIV-1 (EC50: 8.6 nM), low toxicity to MT-4 cells (CC50: 18 μM), useful for AIDS research.</p>
    Fórmula:C25H28N6O
    Cor e Forma:Solid
    Peso molecular:428.53
  • ML67-33

    CAS:
    <p>ML67-33 selectively activates K2P channels; EC50: 36.3 μM (cell-free), 9.7 μM (HEK293). Reversible TREK-1 modulation.</p>
    Fórmula:C18H17Cl2N5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:374.27
  • HEPT

    CAS:
    <p>HEPT is a non-nucleoside inhibitor of HIV-1 reverse transcription.</p>
    Fórmula:C14H16N2O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:308.35
  • L-Ristosamine nucleoside

    CAS:
    <p>L-Ristosamine nucleoside shows antiviral activity.</p>
    Fórmula:C21H21N3O7
    Cor e Forma:Solid
    Peso molecular:427.41
  • Suberosol

    CAS:
    <p>Suberosol possesses anti-HIV replication activity.</p>
    Fórmula:C31H50O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:454.73
  • ZP7

    CAS:
    <p>ZP7 is a HIV-1 replication inhibitor.</p>
    Fórmula:C15H9Br2ClN4OS2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:520.65
  • APA-APA-MPO

    CAS:
    <p>APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.</p>
    Fórmula:C12H25Cl2N5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:326.27
  • Ingenol 3-Hexanoate

    CAS:
    <p>Ingenol 3-Hexanoate is a novel potent reactivator of latent HIV-1.</p>
    Fórmula:C26H38O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:446.58
  • BM 21.1298

    CAS:
    <p>BM 21.1298 is a inhibition of HIV-1 reverse transcriptase.</p>
    Fórmula:C16H13NOS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:267.35
  • D4DAP

    CAS:
    <p>D4DAP is an inhibitor of HIV virus replication.</p>
    Fórmula:C10H12N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:248.24
  • Nitrobenzofuroxan

    CAS:
    <p>Nitrobenzofuroxan, is a HIV-1 and IDO1 inhibitor.</p>
    Fórmula:C6H3N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:181.11
  • BMS-663749 lysine

    CAS:
    <p>BMS-663749 lysine is used as a phosphonooxymethyl prodrug 4 for HIV-1 attachment inhibitor.</p>
    Fórmula:C29H39N6O11P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:678.63
  • GSK5750

    CAS:
    <p>GSK5750 is the ribonuclease H activity inhibitor.</p>
    Fórmula:C16H12N4O2S
    Cor e Forma:Solid
    Peso molecular:324.36
  • 5-Et-ddU

    CAS:
    <p>5-Et-ddU: A pyrimidine nucleoside with anti-HIV-1 activity in human blood cells.</p>
    Fórmula:C11H16N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:240.26
  • L-708906

    CAS:
    <p>L-708906 is the Human Immunodeficiency Virus Type 1 inhibitor.</p>
    Fórmula:C24H20O6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:404.41
  • Dacopafant

    CAS:
    <p>Dacopafant is an antagonist of platlet activationg factor receptor.</p>
    Fórmula:C12H11N3OS
    Cor e Forma:Solid
    Peso molecular:245.3
  • 5M038

    CAS:
    <p>5M038, a novel inhibitor of HIV envelope-mediated fusion, strongly inhibits gp41-mediated membrane fusion.</p>
    Fórmula:C17H8F6N4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:382.26
  • L 738372

    CAS:
    <p>L 738372 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase.</p>
    Fórmula:C18H15N3O
    Cor e Forma:Solid
    Peso molecular:289.33
  • Vif-A3G Inhibitor N.41

    CAS:
    <p>Vif-A3G Inhibitor N.41 is a HIV-1 inhibitor-targeting drug. It causes Vif-dependent degradation of human APOBEC3G, thereby inhibiting the Vif-A3G interaction.</p>
    Fórmula:C15H14N2O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:254.28
  • A 75925

    CAS:
    <p>A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.</p>
    Fórmula:C44H54N4O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:766.92
  • HIV-1 inhibitor-53

    CAS:
    <p>HIV-1 Inhibitor-53 targets HIV-1 protease (IC50: 1.93 nM) and reverse transcriptase (IC50: 2.35 μM), aiding AIDS research.</p>
    Fórmula:C30H34N2O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:582.66
  • Fosdevirine

    CAS:
    <p>Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological related diseases</p>
    Fórmula:C20H17ClN3O3P
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:413.79
  • (S)-BI-1001

    CAS:
    <p>(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).</p>
    Fórmula:C19H15BrClNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:420.68
  • Navuridine

    CAS:
    <p>Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.</p>
    Fórmula:C9H11N5O4
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:253.22
  • Isoescin IA

    CAS:
    <p>Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.</p>
    Fórmula:C55H86O24
    Pureza:96.00%
    Cor e Forma:Solid
    Peso molecular:1131.26
  • L 756423

    CAS:
    <p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>
    Fórmula:C39H48N4O5
    Pureza:99.34% - 99.88%
    Cor e Forma:Solid
    Peso molecular:652.82
  • Opaviraline

    CAS:
    <p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>
    Fórmula:C14H17FN2O3
    Pureza:99.94%
    Cor e Forma:Solid
    Peso molecular:280.29
  • Emivirine

    CAS:
    <p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>
    Fórmula:C17H22N2O3
    Pureza:99.8%
    Cor e Forma:Solid
    Peso molecular:302.37
  • GSK-364735

    CAS:
    <p>GSK-364735 is an HIV-1 IN inhibitor.</p>
    Fórmula:C19H18FN3O4
    Pureza:97.73%
    Cor e Forma:Solid
    Peso molecular:371.36
  • Lenacapavir

    CAS:
    <p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>
    Fórmula:C39H32ClF10N7O5S2
    Pureza:99.61% - 99.87%
    Cor e Forma:Solid
    Peso molecular:968.28
  • AzddMeC

    CAS:
    <p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>
    Fórmula:C10H14N6O3
    Pureza:97.14% - 99.62%
    Cor e Forma:Solid
    Peso molecular:266.26
  • HIV-1 integrase inhibitor 8

    CAS:
    <p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>
    Fórmula:C21H24O2
    Pureza:98.91%
    Cor e Forma:Solid
    Peso molecular:308.41
  • KM-023

    CAS:
    <p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>
    Fórmula:C18H19N3O3
    Pureza:99.47% - >99.99%
    Cor e Forma:Solid
    Peso molecular:325.36
  • BMS-488043

    CAS:
    <p>BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)</p>
    Fórmula:C22H22N4O5
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:422.43
  • (2RS)-FPMPA

    CAS:
    <p>(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).</p>
    Fórmula:C9H13FN5O4P
    Pureza:99.9% - >99.99%
    Cor e Forma:Solid
    Peso molecular:305.2
  • Tenofovir alafenamide fumarate

    CAS:
    <p>Tenofovir alafenamide fumarate (GS-7340) is an oral anti-HIV drug that prevents infection.</p>
    Fórmula:C25H33N6O9P
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:592.54
  • Atevirdine

    CAS:
    <p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>
    Fórmula:C21H25N5O2
    Pureza:98.20%
    Cor e Forma:Solid
    Peso molecular:379.46
  • Suksdorfin

    CAS:
    <p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>
    Fórmula:C21H24O7
    Pureza:98.54%
    Cor e Forma:Solid
    Peso molecular:388.41
  • KNI-272

    CAS:
    <p>Kynostatin-272 is a HIV protease inhibitor. KNI-272 blocked the maturation of viral particles.</p>
    Fórmula:C33H41N5O6S2
    Cor e Forma:Solid
    Peso molecular:667.84