HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 507 produtos de "HIV Protease"

Pureza (%)

100

produtos por página.

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Rolipram
CAS:
- 61413-54-5
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.
Fórmula:C₁₆H₂₁NO₃
Pureza:99.22% - >99.99%
Cor e Forma:Solid
Peso molecular:275.34
Ref: TM-T6644
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PMEDAP
CAS:
- 113852-41-8
PMEDAP is a potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality and an inhibitor of human immunodeficiency
Fórmula:C₈H₁₃N₆O₄P
Pureza:99.77%
Cor e Forma:Solid
Peso molecular:288.2
Ref: TM-T38514
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Lamivudine 13C,15N2
CAS:
- 1391052-30-4
Lamivudine 13C,15N2, a BCH-189 impurity, blocks HIV/HBV reverse transcriptase as an NRTI.
Fórmula:C₈H₉N₃O₄S
Pureza:98%
Cor e Forma:Solid
Peso molecular:246.22
Ref: TM-T11814
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Nelfinavir
CAS:
- 159989-64-7
Nelfinavir (AG1341), with Ki=2 nM, is an HIV treatment and broad-spectrum anticancer drug.
Fórmula:C₃₂H₄₅N₃O₄S
Pureza:98.16% - 99.5%
Cor e Forma:White To Off-White Crystalline Powder
Peso molecular:567.78
Ref: TM-T7779
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Semzuvolimab
CAS:
- 2409099-32-5
Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4).
Cor e Forma:Liquid
Ref: TM-T80621
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Elipovimab
CAS:
- 2101210-43-7
Elipovimab, a potent and broadly neutralizing antibody against HIV-1, targets and eliminates HIV-infected cells [1].
Cor e Forma:Liquid
Ref: TM-T77177
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Suvizumab
CAS:
- 914257-21-9
Suvizumab (KD-247) is a neutralizing anti-HIV-1 antibody with IC50 values of 0.1-1.0 µg/mL; it lowers viral load and prevents infection.
Cor e Forma:Liquid
Ref: TM-T76991
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Nevirapine-d3
CAS:
- 1051419-24-9
Nevirapine-d3 is a deuterated compound of Nevirapine. Nevirapine has a CAS number of 129618-40-2. Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS.
Fórmula:C₁₅H₁₁D₃N₄O
Peso molecular:269.32
Ref: TM-TMID-0206
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Antiviral agent 55
CAS:
- 371137-60-9
Antiviralagent 55 (Compound 95) is an inhibitor of human immunodeficiency viruses 1 and 2 (HIV1 and HIV2), demonstrating antiviral activity.
Fórmula:C₂₁H₂₀N₂O₄
Cor e Forma:Solid
Peso molecular:364.39
Ref: TM-T88222
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Nipamovir
CAS:
- 2651908-78-8
<p>Nipamovir is a nitroimidazole prodrug that exhibits antiviral activity comparable to SAMT-247 and NS-1040 in cellular assays and a human ex vivo model of HIV infection, with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively [1].</p>
Fórmula:C₁₄H₁₅N₅O₄S
Cor e Forma:Solid
Peso molecular:349.37
Ref: TM-T87008
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12-Methoxydodecanoic acid
CAS:
- 92169-28-3
12-Methoxydodecanoic acid, a heteroatom-containing analog of myristic acid, exhibits anti-HIV activity with an IC50 of 6.8 μM. Additionally, it inhibits the Moloney murine leukemia virus (MoMLV).
Fórmula:C₁₃H₂₆O₃
Peso molecular:230.34
Ref: TM-T88770
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Agaritine
CAS:
- 2757-90-6
Agaritine develops from mushrooms.
Fórmula:C₁₂H₁₇N₃O₄
Cor e Forma:Solid
Peso molecular:267.285
Ref: TM-T29710
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Benzalphthalide
CAS:
- 575-61-1
Benzalphthalide (NSC-2824) is a chemical compound with anti-HIV activity.
Fórmula:C₁₅H₁₀O₂
Pureza:99.94%
Cor e Forma:Pale Yellow To Yellow Crystalline Powder
Peso molecular:222.24
Ref: TM-T20489
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Zinlirvimab
CAS:
- 2417213-75-1
Zinlirvimab is a humanized IgG1-λ2 monoclonal antibody that neutralizes HIV by targeting the HIV-1 gp120 envelope glycoprotein, specifically the IIIB gp120 V3
Cor e Forma:Liquid
Ref: TM-T80580
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ZINC36617540
CAS:
- 1174905-91-9
ZINC36617540 is a novel Nef Protein Inhibitor with anti-HIV activity.
Fórmula:C₂₁H₁₇N₅O
Cor e Forma:Solid
Peso molecular:355.39
Ref: TM-T29222
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Fostemsavir disodium
CAS:
- 864953-31-1
Fostemsavir disodium is an HIV-1 attachment inhibitor and prodrug of the small-molecule inhibitor BMS-626529.
Fórmula:C₂₅H₂₄N₇Na₂O₈P
Cor e Forma:Solid
Peso molecular:627.45
Ref: TM-T68509
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gp120-IN-2
CAS:
- 123629-42-5
gp120-IN-2 is a potent HIV-1 inhibitor (IC50 = 7.5 μM) with low cytotoxicity (CC50 = 112.93 μM).
Fórmula:C₁₅H₁₈N₂O₅
Cor e Forma:Solid
Peso molecular:306.31
Ref: TM-T60714
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DPC-961
CAS:
- 214287-88-4
DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
Fórmula:C₁₄H₁₀ClF₃N₂O
Cor e Forma:Solid
Peso molecular:314.69
Ref: TM-T27203
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A 80987
CAS:
- 144141-97-9
A 80987 is an inhibitor of HIV-1 protease.
Fórmula:C₃₇H₄₃N₅O₆
Cor e Forma:Solid
Peso molecular:653.77
Ref: TM-T26451
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HIV-1 protease-IN-1
CAS:
- 2765293-30-7
HIV-1 protease-IN-1, potent HIV inhibitor; IC50=90pM, fights B/C-HIV strains with EC50=89-13.59/8.23nM.
Fórmula:C₂₅H₃₅N₃O₆S
Cor e Forma:Solid
Peso molecular:505.63
Ref: TM-T63453