HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 506 produtos de "HIV Protease"

Pureza (%)

100

produtos por página.

+ Info
(S)-BI-1001
CAS:
- 957889-73-5
(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).
Fórmula:C₁₉H₁₅BrClNO₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:420.68
Ref: TM-T16829
+ Info
HIV-IN-4
CAS:
- 2408729-03-1
HIV-IN-4 (Compound 12) is a potent HIV inhibitor that exhibits promising anti-HIV activities [1].
Fórmula:C₁₄H₁₈N₂O₃
Cor e Forma:Solid
Peso molecular:262.3
Ref: TM-T60426
+ Info
HIV-1 inhibitor-16
CAS:
- 2719675-72-4
HIV-1 inhibitor-16: potent with EC50 1.3 nM for wild-type; inhibits K103N, E138K, Y181C, L100I strains; good solubility; stable; low CYP impact; non-toxic.
Fórmula:C₂₃H₁₆F₂N₆
Cor e Forma:Solid
Peso molecular:414.41
Ref: TM-T62129
+ Info
HIV-1 inhibitor-57
CAS:
- 2745197-24-2
<p>HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50</p>
Fórmula:C₂₅H₂₄FN₅O₃S
Cor e Forma:Solid
Peso molecular:493.55
Ref: TM-T78749
+ Info
SARS-CoV-IN-3
CAS:
- 888958-27-8
SARS-CoV-IN-3 is an effective SARS-CoV replication inhibitor.
Fórmula:C₂₅H₂₈ClFeN₃O
Pureza:98%
Cor e Forma:Solid
Peso molecular:477.81
Ref: TM-T12839
+ Info
Mesoxalic acid
CAS:
- 473-90-5
Mesoxalic acid is a dicarboxylic acid and a ketonic acid which blocks RT translocation.
Fórmula:C₃H₂O₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:118.04
Ref: TM-T25792
+ Info
SAMT-247
CAS:
- 850715-59-2
SAMT-247 is an HIV inhibitor that acts by modifying the nucleocapsid NCp7 region of Gag in infected cells and blocking Gag processing and reducing infectivity.
Fórmula:C₁₂H₁₄N₂O₃S
Cor e Forma:Solid
Peso molecular:266.32
Ref: TM-T24756
+ Info
TMC310911
CAS:
- 1000287-05-7
TMC310911 is an oral HIV-1 protease inhibitor with an EC50 of 2.2-14.2 nM, effective against various HIV-1 strains.
Fórmula:C₃₈H₅₃N₅O₇S₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:755.99
Ref: TM-T17106
+ Info
Reverse transcriptase-IN-3
Reverse transcriptase-IN-3, a pyrimidine carboxamide, inhibits HIV-1 including mutant strains.
Fórmula:C₂₈H₃₁N₇O₄S
Cor e Forma:Solid
Peso molecular:561.66
Ref: TM-T72203
+ Info
DQBS
CAS:
- 372087-80-4
DQBS is an HIV-1 Nef function antagonist.
Fórmula:C₂₂H₁₇ClN₄O₄S
Pureza:98%
Cor e Forma:Solid
Peso molecular:468.91
Ref: TM-T24017
+ Info
HIV-1 integrase inhibitor 7
CAS:
- 204268-03-1
HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).
Fórmula:C₃₀H₂₆O₁₆
Pureza:98%
Cor e Forma:Solid
Peso molecular:642.52
Ref: TM-T11565
+ Info
β-L-D4A
CAS:
- 7057-48-9
beta-L-D4A inhibits HIV-1 reverse transcriptase, stopping DNA synthesis.
Fórmula:C₁₀H₁₁N₅O₂
Pureza:99.45%
Cor e Forma:Solid
Peso molecular:233.23
Ref: TM-FL0097
+ Info
MK-4965
CAS:
- 920035-77-4
MK-4965 is a new type of non-nucleoside reverse transcriptase inhibitor with antiviral activity.
Fórmula:C₂₀H₁₃Cl₂N₅O₂
Cor e Forma:Solid
Peso molecular:426.26
Ref: TM-T33435
+ Info
gp120-IN-1
CAS:
- 5948-75-4
gp120-IN-1 (4e) is a potent HIV-1 inhibitor, IC50 2.2 μM, CC50 100.90 μM, and blocks HIV entry.
Fórmula:C₁₅H₁₈N₂O₄S
Cor e Forma:Solid
Peso molecular:322.38
Ref: TM-T60871
+ Info
HIV-1 inhibitor-25
CAS:
- 2475658-74-1
Compound R-12a is a potent HIV-1 reverse transcriptase inhibitor (IC50: 0.1061 nM), with low cytotoxicity and effective against multiple mutants.
Fórmula:C₂₆H₁₉N₅O₂
Cor e Forma:Solid
Peso molecular:433.46
Ref: TM-T62431
+ Info
LEDGIN6
CAS:
- 957890-42-5
HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.
Fórmula:C₂₁H₂₀ClNO₂
Cor e Forma:Solid
Peso molecular:353.84
Ref: TM-T15483
+ Info
NIT
CAS:
- 299922-10-4
NIT is an HIV-1 protease inhibitor.
Fórmula:C₁₅H₇N₃O₄S₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:357.36
Ref: TM-T24536
+ Info
HIV-1 inhibitor-36
CAS:
- 2170506-18-8
HIV-1 inhibitor-36 (Compound 2) is a potent HIV-1 inhibitor with significant potential as a novel latency reversing agent [1].
Fórmula:C₁₄H₁₄Cl₂N₂O₂S
Cor e Forma:Solid
Peso molecular:345.24
Ref: TM-T61134
+ Info
HIV-1 inhibitor-24
CAS:
- 2475658-75-2
HIV-1 inhibitor-24 (S-12a) blocks HIV reverse transcription effectively (IC50: 9.5 nM), low toxicity, well-tolerated in mice, good heart safety.
Fórmula:C₂₆H₁₉N₅O₂
Cor e Forma:Solid
Peso molecular:433.46
Ref: TM-T62430
+ Info
DPC-681
CAS:
- 284661-68-3
DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1).
Fórmula:C₃₅H₄₈FN₅O₅S
Cor e Forma:Solid
Peso molecular:669.85
Ref: TM-T15163