
HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 506 produtos de "HIV Protease"
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HIV-1 inhibitor-19
CAS:HIV-1 inhibitor-19 is a potent NNRTI targeting L100I, K103N, V106A/F227L mutants; EC50s: 7.3, 9.2, 21.0 nM respectively.Fórmula:C24H22BClN2O5SCor e Forma:SolidPeso molecular:496.77HIV-1 inhibitor-15
CAS:HIV-1 inhibitor-15 (compound 9d): Potent, broad-spectrum, EC50=1.7-9 nM for various strains, good solubility/safety, oral use.Fórmula:C24H20N6Cor e Forma:SolidPeso molecular:392.46TX-1918
CAS:TX-1918, a tyrphostin, blocks eEF-2K to hinder HepG2, HCT116 cell growth.Fórmula:C14H12O3Cor e Forma:SolidPeso molecular:228.24S 2720
CAS:S 2720 is a human immunodeficiency virus type 1 (HIV-1)-specific reverse transcriptase (RT) inhibitor quinoxaline.Fórmula:C14H15ClN2O2SCor e Forma:SolidPeso molecular:310.81E7-03
CAS:1E7-03 is an inhibitor of HIV-1 transcription, by targeting host Protein Phosphatase-1 (PP1).Fórmula:C28H29N3O6Cor e Forma:SolidPeso molecular:503.55DPC-961
CAS:DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C14H10ClF3N2OCor e Forma:SolidPeso molecular:314.69B07 hydrochloride
CAS:B07 hydrochloride is a CCR5 antagonist-based inhibitor of HIV-1 entry.Fórmula:C29H38ClFN4O2Pureza:98%Cor e Forma:SolidPeso molecular:529.09GCA-186
CAS:GCA-186 is an effective non-nucleoside HIV-1 reverse transcriptase inhibitor.Fórmula:C19H26N2O3Pureza:98%Cor e Forma:SolidPeso molecular:330.42HIV-1 inhibitor-20
CAS:HIV-1 inhibitor-20 is a potent HIV-1 inhibitor.Fórmula:C19H11ClF3N3O2Cor e Forma:SolidPeso molecular:405.76BMS-585248
CAS:BMS-585248 is a highly effective HIV-1 adhesion inhibitor that targets the viral envelope protein gp120.Fórmula:C22H18FN7O3Cor e Forma:SolidPeso molecular:447.42AIC-292
CAS:AIC-292 is a potent, tolerable reverse transcriptase inhibitor active against various HIV-1 strains, including NNRTI-resistant K103N, G190A, Y181C.Fórmula:C19H12Cl2F2N4O2Cor e Forma:SolidPeso molecular:437.23Tivirapine
CAS:Tivirapine, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C16H20ClN3SCor e Forma:SolidPeso molecular:321.87L 739594
CAS:L 739594 is an inhibitor of HIV-1 protease.Fórmula:C31H47N3O6Pureza:98%Cor e Forma:SolidPeso molecular:557.72HIV-1 inhibitor-28
CAS:HIV-1 inhibitor-28: potent, selective, EC50=58 nM, low MT-4 cell toxicity (CC50=38.6 μM), valuable in AIDS research.Fórmula:C26H32N6O3SCor e Forma:SolidPeso molecular:508.64BMS-663749
CAS:BMS-663749 is an attachment inhibitor of human immunodeficiency virus type 1 (HIV-1).Fórmula:C23H25N4O9PCor e Forma:SolidPeso molecular:532.44HIV-1 inhibitor-45
CAS:HIV-1 inhibitor-45 is a potent inhibitor of HIV-1 RNase H (IC50: 0.067 μM) and has antiviral effects.Fórmula:C23H24N4O8SCor e Forma:SolidPeso molecular:516.52HIV-1 inhibitor-21
CAS:HIV-1 inhibitor-21 (compound 9b) blocks HIV-1 RT effectively (IC50: 0.55 μM), targeting wild-type and K103N strains, with low toxicity (CC50: 10.2 μM).Fórmula:C28H24N6O2Cor e Forma:SolidPeso molecular:476.53GSK-364735 potassium
CAS:GSK-364735 potassium is an HIV-1 IN inhibitor.Fórmula:C19H17FKN3O4Cor e Forma:SolidPeso molecular:409.46HI-236
CAS:HI-236 is used as a non-nucleoside HIV-1 reverse-transcriptase inhibitor.Fórmula:C16H18BrN3O2SPureza:98%Cor e Forma:SolidPeso molecular:396.3Adenallene
CAS:Adenallene inhibits replication and cytopathic effects of HIV in vitro.Fórmula:C9H9N5OPureza:98%Cor e Forma:SolidPeso molecular:203.2
