HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 486 produtos para "HIV Protease".
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HIV-1 protease-IN-15
CAS:HIV-1protease-IN-15 (Compound 27) is an orally active selective inhibitor of HIV-1 protease (HIV-1protease) with a pIC50 of 9.347. It inhibits the maturation of HIV proteins, effectively blocking viral replication. HIV-1protease-IN-15 shows potential for research into HIV-1 infection.Fórmula:C27H36F3N3O4SCor e Forma:SolidPeso molecular:555.65HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Fórmula:C37H37ClN2O6S2Cor e Forma:SolidPeso molecular:705.28ATPase-IN-6
CAS:ATPase-IN-6 is an inhibitor of H+/K+-ATPase (ATPase) and a derivative of imidazopyridine. It exhibits significant antiviral activity against various viruses, such as HIV-1 and SARS-CoV-2. ATPase-IN-6 is applicable in antiviral infection research.Fórmula:C29H25N3O4SCor e Forma:SolidPeso molecular:511.59Lamivudine, (+/-)-trans-
CAS:Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.Fórmula:C8H11N3O3SPureza:98%Cor e Forma:SolidPeso molecular:229.26Saphenamycin
CAS:Saphenamycin is an antibiotic from a strain of Streptomyces.Fórmula:C23H18N2O5Pureza:98%Cor e Forma:SolidPeso molecular:402.40HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Fórmula:C46H72FNO5SCor e Forma:SolidPeso molecular:770.13NBD-14189
CAS:NBD-14189: Potent HIV-1 entry blocker, binds gp120, IC50: 89 nM, strong antiviral (EC50 <200 nM).Fórmula:C18H16F4N4O2SCor e Forma:SolidPeso molecular:428.40BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Fórmula:C33H43N5O4Pureza:98%Cor e Forma:SolidPeso molecular:573.73NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Fórmula:C20H25ClN4O3SPureza:98%Cor e Forma:SolidPeso molecular:436.96HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Fórmula:C16H15F2N3OSCor e Forma:SolidPeso molecular:335.37Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Fórmula:C8H13FN3O12P3SCor e Forma:SolidPeso molecular:487.19HIV-1-IN-86
CAS:HIV-1-IN-86 (compound 6m) is an HIV-1 inhibitor with an EC50 of 0.77 μM, exhibiting antiviral activity.Fórmula:C20H17N3O7SCor e Forma:SolidPeso molecular:443.43ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Fórmula:C27H22D6N6O3S2Cor e Forma:SolidPeso molecular:554.72BI-2540
CAS:BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .Fórmula:C24H15ClF5NO5Cor e Forma:SolidPeso molecular:527.83Desthiazolylmethyl ritonavir
CAS:Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.Fórmula:C33H43N5O4SCor e Forma:SolidPeso molecular:605.791Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Fórmula:C43H67FN2O4SCor e Forma:SolidPeso molecular:727.07HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Fórmula:C27H31N3O6SCor e Forma:SolidPeso molecular:525.62HI-280
CAS:HI-280 is an inhibitor of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. It is utilized in research related to infections.Fórmula:C17H21NOS2Peso molecular:319.48BRN3OMe
CAS:BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.Fórmula:C7H13N3O4Cor e Forma:SolidPeso molecular:203.196Integrase-LEDGF/p75 allosteric inhibitor 1
CAS:Oral HIV-1 allosteric integrase inhibitor, blocks DNA integration, antiviral, potent against NL432 (EC50: 3.9 nM).Fórmula:C33H41NO6SCor e Forma:SolidPeso molecular:579.75
