HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 502 produtos de "HIV Protease"

Pureza (%)

100

produtos por página.

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Gardiquimod hydrochloride
CAS:
- 2956183-81-4
Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.
Fórmula:C₁₇H₂₄ClN₅O
Cor e Forma:Solid
Peso molecular:349.858
Ref: TM-T204751
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BMS-818251
CAS:
- 2974489-09-1
BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.
Fórmula:C₂₉H₂₆N₆O₅S
Cor e Forma:Solid
Peso molecular:570.619
Ref: TM-T204307
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A 76889
CAS:
- 134805-77-9
A 76889 is an inhibitor of HIV-1 protease.
Fórmula:C₄₄H₅₈N₈O₆
Pureza:98%
Cor e Forma:Solid
Peso molecular:794.98
Ref: TM-T26445
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GS-9822
CAS:
- 2219362-41-9
GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.
Fórmula:C₃₆H₃₉ClN₄O₄S
Cor e Forma:Solid
Peso molecular:659.24
Ref: TM-T69782
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L 702007
CAS:
- 139547-89-0
L 702007 is an inhibitor of HIV-1 reverse transcriptase.
Fórmula:C₁₈H₂₅N₃O₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:315.41
Ref: TM-T24346
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Lentiginosine
CAS:
- 125279-72-3
Lentiginosine is a selective amyloglucosidase inhibitor.
Fórmula:C₈H₁₅NO₂
Cor e Forma:Solid
Peso molecular:157.21
Ref: TM-T25662
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NBD-10007
CAS:
- 1375736-65-4
NBD-10007 is an inhibitor of HIV-1 entry.
Fórmula:C₂₀H₂₅ClN₄O₃S
Pureza:98%
Cor e Forma:Solid
Peso molecular:436.96
Ref: TM-T24522
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Lamivudine, (+/-)-trans-
CAS:
- 131086-22-1
Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.
Fórmula:C₈H₁₁N₃O₃S
Pureza:98%
Cor e Forma:Solid
Peso molecular:229.26
Ref: TM-T25609
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HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.
Fórmula:C₂₁H₃₂ClN₇O₃
Cor e Forma:Solid
Peso molecular:465.98
Ref: TM-T62978
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ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>
Cor e Forma:Solid
Ref: TM-T64303
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4'-Ethynyl-2'-deoxyadenosine
CAS:
- 306305-07-7
4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).
Fórmula:C₁₂H₁₃N₅O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:275.26
Ref: TM-T10141
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(S)-Batylalcohol
CAS:
- 6129-13-1
<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>
Fórmula:C₂₁H₄₄O₃
Cor e Forma:Solid
Peso molecular:344.572
Ref: TM-T204561
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Desthiazolylmethyl ritonavir
CAS:
- 256328-82-2
Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.
Fórmula:C₃₃H₄₃N₅O₄S
Cor e Forma:Solid
Peso molecular:605.791
Ref: TM-T204277
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HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.
Fórmula:C₁₆H₁₅F₂N₃OS
Cor e Forma:Solid
Peso molecular:335.37
Ref: TM-T61031
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HIV-1 inhibitor-61
CAS:
- 1114507-62-8
HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].
Fórmula:C₂₄H₂₄F₂N₂O₂S
Cor e Forma:Solid
Peso molecular:442.52
Ref: TM-T86580
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Fipravirimat
CAS:
- 1818867-24-1
Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.
Fórmula:C₄₃H₆₇FN₂O₄S
Cor e Forma:Solid
Peso molecular:727.07
Ref: TM-T70147
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HIV-1 inhibitor-40
HIV-1 inhibitor-40 (4ab) is a potent NNRTI (EC50: 1.9 nM), non-toxic in vivo, and a sensitive CYP inhibitor.
Fórmula:C₂₅H₁₈N₆O₂
Cor e Forma:Solid
Peso molecular:434.45
Ref: TM-T62452
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HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).
Fórmula:C₂₇H₃₁N₃O₆S
Cor e Forma:Solid
Peso molecular:525.62
Ref: TM-T63687
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HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.
Fórmula:C₂₇H₃₁FN₂O₆S
Cor e Forma:Solid
Peso molecular:530.61
Ref: TM-T63733
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HIV-1 inhibitor-14
HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.
Fórmula:C₂₉H₃₂N₆O₄S
Cor e Forma:Solid
Peso molecular:560.67
Ref: TM-T63963