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HIV Protease

HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 447 produtos de "HIV Protease"

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  • Cys-TAT(47-57)

    CAS:
    <p>Cys-TAT(47-57): arginine-rich peptide from HIV-1 TAT protein's transduction domain.</p>
    Fórmula:C67H124N34O14S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1661.99
  • Kuguacin N


    <p>Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.</p>
    Fórmula:C30H46O4
    Cor e Forma:Solid
    Peso molecular:470.694
  • CTP518

    CAS:
    <p>CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.</p>
    Fórmula:C38H52N6O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:719.95
  • 12-Oxocalanolide A


    <p>12-Oxocalanolide A is a useful organic compound for research related to life sciences and the catalog number is T125675.</p>
    Fórmula:C22H24O5
    Cor e Forma:Solid
    Peso molecular:368.429
  • HIV gag peptide (197-205)

    CAS:
    <p>HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETI</p>
    Fórmula:C45H81N11O14S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1064.32
  • TAT peptide


    <p>TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.</p>
    Fórmula:C65H124N34O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1621.91
  • Kni 102

    CAS:
    <p>Kni 102 is a biochemical.</p>
    Fórmula:C31H41N5O7
    Cor e Forma:Solid
    Peso molecular:595.69
  • HIV-1 inhibitor-81


    <p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>
    Fórmula:C32H44N2O8S
    Cor e Forma:Solid
    Peso molecular:616.77
  • HIV-1 inhibitor-6 

    CAS:
    <p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>
    Fórmula:C14H10N4O4S
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:330.32
  • Scirpusin A

    CAS:
    <p>Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.</p>
    Fórmula:C28H22O7
    Cor e Forma:Solid
    Peso molecular:470.47
  • Aureothin

    CAS:
    <p>Aureothin: a nitroaryl polyketide with antitumor, antifungal &amp; insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>
    Fórmula:C22H23NO6
    Cor e Forma:Solid
    Peso molecular:397.42
  • NNRT-IN-6


    <p>NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.</p>
    Fórmula:C32H31N9O3S
    Cor e Forma:Solid
    Peso molecular:621.71
  • (2S,5S)-Censavudine


    <p>(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.</p>
    Fórmula:C12H12N2O4
    Cor e Forma:Solid
    Peso molecular:248.23
  • Salvianan A

    CAS:
    <p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>
    Fórmula:C20H17NO2
    Cor e Forma:Solid
    Peso molecular:303.35
  • Bictegravir Sodium

    CAS:
    <p>Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.</p>
    Fórmula:C21H17F3N3NaO5
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:471.36
  • NF279

    CAS:
    <p>P2X1 antagonist</p>
    Fórmula:C49H36N6Na6O23S6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1407.17
  • Decanoyl-RVKR-CMK

    CAS:
    <p>Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.</p>
    Fórmula:C34H66ClN11O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:744.42
  • HIV-IN-9


    <p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>
    Cor e Forma:Odour Solid
  • HIV-1 protease-IN-14


    <p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>
    Cor e Forma:Odour Solid
  • Carbovir triphosphate

    CAS:
    <p>Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].</p>
    Fórmula:C11H16N5O11P3
    Cor e Forma:Solid
    Peso molecular:487.19