HIV Protease
Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.
Foram encontrados 501 produtos de "HIV Protease"
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Kuguacin N
Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.Fórmula:C30H46O4Cor e Forma:SolidPeso molecular:470.694HIV gag peptide (197-205)
CAS:HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein and composed of the amino acid 197-205 (AMQMLKETIFórmula:C45H81N11O14S2Pureza:98%Cor e Forma:SolidPeso molecular:1064.32HIV-1 inhibitor-81
HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.Fórmula:C32H44N2O8SCor e Forma:SolidPeso molecular:616.77HIV p17 Gag (77-85)
CAS:Targeting HIV Gag p17 (77-85) with intracellular Ab cDNA disrupts viral replication pre/post-integration.Fórmula:C44H72N10O15Pureza:98%Cor e Forma:SolidPeso molecular:981.1HIV-1 inhibitor-11
HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.Fórmula:C42H36ClF10N7O5S2Cor e Forma:SolidPeso molecular:1008.35Peptide T TFA
CAS:Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.Fórmula:C37H56F3N9O18Pureza:98%Cor e Forma:SolidPeso molecular:971.89GLR-19
CAS:GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].Fórmula:C102H194N40O20Pureza:98%Cor e Forma:SolidPeso molecular:2300.89SPD-756
CAS:SPD-756, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C12H16N6O3Pureza:98%Cor e Forma:SolidPeso molecular:292.29NNRT-IN-6
NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.Fórmula:C32H31N9O3SCor e Forma:SolidPeso molecular:621.71TAT peptide
TAT peptide, a CPP, delivers molecules into cells by traversing membrane barriers using aa49-57 of TAT protein.Fórmula:C65H124N34O15Pureza:98%Cor e Forma:SolidPeso molecular:1621.91Clavirolide L
Clavirolide L (Compound 3), a dolabellane-type diterpenoid isolated from Clavularia viridis, demonstrates significant inhibition against HIV-1 withoutFórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.43Decanoyl-RVKR-CMK
CAS:Inhibits all seven proprotein convertases; stops proET-1 processing; hinders VGF secretion in PC12 cells.Fórmula:C34H66ClN11O5Pureza:98%Cor e Forma:SolidPeso molecular:744.42Tenofovir-C3-O-C15-CF3 ammonium
CAS:Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.Fórmula:C28H52F3N6O5PCor e Forma:SolidPeso molecular:640.73Bictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Fórmula:C21H17F3N3NaO5Pureza:99.97%Cor e Forma:SolidPeso molecular:471.36HIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Cor e Forma:Odour SolidIndoline
CAS:Compound PDK0239, with CAS No. 496-15-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0239 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Fórmula:C8H9NCor e Forma:Clear To Yellow LiquidPeso molecular:119.16VIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Fórmula:C109H158N22O25S2Pureza:98%Cor e Forma:SolidPeso molecular:2240.7HIV-1 inhibitor-59
HIV-1 Inhibitor-59 (Compound I-5b) effectively inhibits both wild-type and mutant strains of HIV-1, with EC50 values ranging from 5.62 to 171 nM.Fórmula:C28H28FN5O3SCor e Forma:SolidPeso molecular:533.62
