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HIV Protease

HIV Protease

Os inibidores da protease do HIV são uma classe de medicamentos antirretrovirais que têm como alvo específico a enzima protease do vírus da imunodeficiência humana (HIV). Ao inibir esta enzima, esses compostos impedem o vírus de processar suas poliproteínas em proteínas maduras e funcionais, bloqueando assim a produção de novos virions infecciosos. Os inibidores da protease do HIV são um pilar da terapia antirretroviral altamente ativa (HAART) utilizada para o tratamento do HIV/AIDS. Na CymitQuimica, oferecemos uma variedade de inibidores da protease do HIV para apoiar sua pesquisa em tratamento do HIV, resistência a medicamentos e virologia.

Foram encontrados 497 produtos de "HIV Protease"

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  • Atazanavir sulfate

    CAS:
    Atazanavir sulfate, an azapeptide HIV-protease inhibitor, treats HIV/AIDS alongside other anti-HIV drugs.
    Fórmula:C38H52N6O7·H2SO4
    Pureza:99.31% - 99.40%
    Cor e Forma:Solid
    Peso molecular:802.93
  • Probenecid

    CAS:
    <p>Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.</p>
    Fórmula:C13H19NO4S
    Pureza:98.95% - 99.84%
    Cor e Forma:Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)
    Peso molecular:285.36
  • Globotriaosylceramides (porcine)

    CAS:
    Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.
    Fórmula:C60H113NO18
    Cor e Forma:Solid
    Peso molecular:1136.553
  • Salvianan A

    CAS:
    <p>1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) serves as an effective anti-HIV-1 agent [1].</p>
    Fórmula:C20H17NO2
    Cor e Forma:Solid
    Peso molecular:303.35
  • L 754394

    CAS:
    L 754394 is an effective and specific inhibitor of the HIV-1 protease.
    Fórmula:C38H47N5O5
    Cor e Forma:Solid
    Peso molecular:653.81
  • Protease Inhibitor Library


    A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
    Cor e Forma:Odour Solid
  • Bictegravir Sodium

    CAS:
    Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.
    Fórmula:C21H17F3N3NaO5
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:471.36
  • GLR-19

    CAS:
    GLR-19 is an anti-HIV peptide with demonstrated antiviral activity against HSV-2 [1] [2].
    Fórmula:C102H194N40O20
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2300.89
  • HIV-1 protease-IN-14


    <p>HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.</p>
    Cor e Forma:Odour Solid
  • HIV-1 inhibitor-11


    HIV-1 inhibitor-11, a fused pyridine ring derivative, is a HIV-1 inhibitor.
    Fórmula:C42H36ClF10N7O5S2
    Cor e Forma:Solid
    Peso molecular:1008.35
  • Scirpusin A

    CAS:
    Scirpusin A is a hydroxystilbene dimer from the rhizome of Scirpus fluviatilis and Xinjiang wine grape.
    Fórmula:C28H22O7
    Cor e Forma:Solid
    Peso molecular:470.47
  • HIV-1 inhibitor-6 

    CAS:
    <p>HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing</p>
    Fórmula:C14H10N4O4S
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:330.32
  • Peptide T TFA

    CAS:
    Peptide T (TFA), an octapeptide from HIV-1 gp120, inhibits HIV binding to CD4.
    Fórmula:C37H56F3N9O18
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:971.89
  • HIV-1 inhibitor-58


    HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type
    Fórmula:C26H24N6O2
    Cor e Forma:Solid
    Peso molecular:452.51
  • HIV-1 protease-IN-10


    <p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>
    Fórmula:C23H40O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:396.56
  • Kuguacin N


    Kuguacin N is a useful organic compound for research related to life sciences and the catalog number is T126345.
    Fórmula:C30H46O4
    Cor e Forma:Solid
    Peso molecular:470.694
  • Peptide T

    CAS:
    Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.
    Fórmula:C35H55N9O16
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:857.86
  • HIV-1 inhibitor-81


    HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.
    Fórmula:C32H44N2O8S
    Cor e Forma:Solid
    Peso molecular:616.77
  • BNM-III-170

    CAS:
    <p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>
    Fórmula:C25H26ClF7N6O6
    Cor e Forma:Solid
    Peso molecular:674.96
  • NNRT-IN-6


    NNRT-IN-6 (Compound 13a) is a non-nucleoside reverse transcriptase inhibitor (NNRT) used to inhibit HIV-1 reverse transcriptase (HIV-1RT), with an IC50 of 0.41 μM. It effectively suppresses both wild-type HIV-1 and mutants L100I, K103N, Y181C, Y188L, E138K, F227L/V106A, and RES056, with an EC50 range of 6.2-250 nM.
    Fórmula:C32H31N9O3S
    Cor e Forma:Solid
    Peso molecular:621.71