Antibacteriano

Hikizimycin is a potent anthelmintic and antibacterial natural product.

Collismycin A, from Streptomyces, has antibacterial, antiproliferative, and neuroprotective effects. It inhibits various cancer cells and is iron-complexing.

CAY10742: Oral oxadiazole antibiotic, combats Gram-positive bacteria & MRSA, effective against resistant strains, works in mouse models. MICs = 1-4 μg/ml.

Arylomycin B2 is an antibiotic and a potent inhibitor of signal peptidase I (SPase I), exhibiting activity against Gram-positive bacteria.

Lymecycline is a semisynthetic antibiotic. It is related to TETRACYCLINE.

Lankacyclinol A is a Lankacidin antibiotic.

Ambazone hydrate has anti-cancer activity.

Clovibactin, a novel antibiotic, effectively eradicates drug-resistant bacterial pathogens and demonstrates no discernible resistance.

Antibacterial agent 59 (example 24) is a antibacterial agent.

Luteoreticulin, a nitro-containing bacterial metabolite first isolated from S. luteoreticuli, exhibits mosquitocidal activity against A. aegypti at a concentration of 6.25 mg/L and nematocidal activity against C. elegans.

Deethylindanomycin, a polyether antibiotic from S. setonii, combats Gram-positive bacteria and in vitro coccidia; ionophore selective for K+ ions.

Adenoregulin (Dermaseptin b2), an antimicrobial peptide antibiotic, exhibits efficacy against both Gram-negative and Gram-positive bacteria, as well as yeast

Meleagrin: Penicillium-derived alkaloid, inhibits FabI and c-Met, targets breast cancer metastasis, antimicrobial.

KPC-2-IN-1, a boronic acid KPC-2 inhibitor (Ki 0.032 μM), boosts cefotaxime against KPC-2 E. coli; tolerable in HEK-293 cells.

CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor.

DprE1-IN-5 (Compound 10), a potent DprE1 inhibitor, exhibits anti-TB activity with an MIC of 4 μM against the Mtb H37Rv strain and demonstrates

3′-Omethyl-5′-hydroxydiplacone (compound 2), a C-6-geranylflavonoid isolated from the ethanol extract of Paulownia tomentosa fruits, exhibits antibacterial

pBD-1: Endogenous AMP in pigs, expressed constitutively in mucosal epithelia for host defense.

K-252c is a staurosporine analog isolated from Nocardiopsis sp.

Antibacterial agent 32 fights E. coli (NCTC 13351, M 50, 7 MP) with MICs: 1, 2, 8 mcg/mL.

Dihydrotetrodecamycin, a fungal metabolite extracted from S. nashvillensis, exhibits antibacterial properties. It demonstrates activity against the fish-pathogenic bacterium P. piscicida.

T3SS-IN-3 (compound F-24) serves as an inhibitor specific to the type III secretion system (T3SS), significantly reducing the transcription of the hrpY gene

AA58 enhances Ceftazidime efficacy by lowering its MIC.

CRAMP-18 (mouse) is an antibiotic peptide with demonstrated efficacy against Gram-negative bacteria, including S.

2,4,6-trichloroanisole inhibits the cell viability of CHO and C32 cell lines and apoptosis, antibacterial activity against Plasmodium falciparum.

SEQ-9 is an orally active inhibitor targeting the Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome, demonstrating an inhibitory concentration (IC50)

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.

Plaunotol is a gastric protective agent that increases prostaglandins in the gastric mucosa and accelerates ulcer healing.

Cephabacin M6 is a new cephem antibiotic isolated from bacterial.

DPH: antihistamine for cough, nausea, itching, allergy, Parkinson's, sleep aid, cold remedy.

ETX0462, a gram-negative antibiotic, effectively targets Pseudomonas aeruginosa, ESKAPE pathogens, Stenotrophomonas maltophilia, and biothreats.

Amythiamicin B is a novel antimicrobial antibiotic.

Mycophenolate Mofetil: Non-competitive, selective inhibitor of IMP dehydrogenase I/II, IC50: 39/27 nM.

ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.

Kapurimycin A2 is an antitumor antibiotics.

A unique collection of 904 antibacterial bioactive compounds, a powerful tool for antibacterial drug development;

Carbomycin is a bioactive chemical against Borrelia burgdorferi persisters (lyme disease).

Desacetyl cefapirin, a cefapirin metabolite, combats E. coli, K. pneumoniae, P. mirabilis, S. aureus; MICs: 120, 24, 34, 0.42 μg/ml.

ANT3310 inhibits several Serine β-Lactamases (IC50: 1-175 nM); useful for bacterial infection research.

Isouvaretin demonstrates potent antibacterial activity against B. subtilis and S. epidermidis.

2-Acetylthiophene thiosemicarbazone is an antimicrobial agent against a wide range of gram-negative and gram-positive bacteri and fungi.

Compound PDK0095, with CAS No. 1777-82-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0095 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Ceratotoxin A acetate is isolated from the accessory gland secretion fluid, with anti-bacterial effects.

Efflux pump-IN-2 is an AcrB inhibitor that boosts antibiotic effects and blocks Nile Red efflux, non-toxic to nematodes.

Agent 46 from patent WO2013030735A1, example 9, is a potent antibacterial with research potential.

Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide from Bombina species.

AM-8191, a bacterial topoisomerase inhibitors, has broad-spectrum antibacterial activity.

Tigecycline hydrate: broad-spectrum, glycylcycline antibiotic, bacteriostatic, inhibits protein synthesis, effective against resistant bacteria.

Poly(hexamethylenebiguanide) hydrochloride (PHMB HCl) is an antibacterial agent and cationic disinfectant against Gram-negative and Gram-positive bacteria.

2,2-Dithiobis(Benzothiazole) inhibits MAPK8 and Pseudomonas aeruginosa and is commonly used as an accelerator in rubber and plastic synthesis.

A unique collection of xnum species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS);

Aurein 2.3, an antibiotic antimicrobial peptide, partially inhibits E. coli ATPase activity and suppresses cell growth [1] [2].

Enrofloxacin monohydrochloride, an antibiotic, has MIC 90 of 0.312 μg/mL for M. bovis and inhibits vaccinia virus.

4-Aminosalicylic acid (Standard) is the standard substance of 4-Aminosalicylic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Sulfadimethoxine D4 is a deuterium labeled Sulfadimethoxine (Sulphadimethoxine). Sulfadimethoxine is a sulfonamide antibiotic used to treat many infections.

Cefalexin hydrochloride is a cephalosporin antibiotic.

Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic properties.

Benzothiohydrazide is an analog of isoniazid with anti-tuberculosis activity and can be used to isolate fungi and bacteria.

Sulfathiazole (Standard) is the standard substance of Sulfathiazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.

N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2], facilitates bacterial gene expression modulation in response to cell density escalation and triggers IL-8 production in 16HBE human bronchial epithelial cells [3].

Enrofloxacin-d5 is a deuterium marker for Enrofloxacins.(BAY-Vp2674) is an antibiotic that acts against Mycoplasma bovis and has a MIC90 of 0.312 μg/mL.

2-Chloroacetamide: a preservative, herbicide, and biocide used in agriculture, glues, paints, with inhibitory effects on fatty acid elongase.

AN0128 (CRM-0005) is a boron-containing antibacterial agent with anti-inflammatory activity, inhibiting S. aureus, and used in dermatological research.

Iron (III) hexacyanoferrate (II) is a useful organic compound for research related to life sciences.

Ampicillin-d5 is a 2H-labeled Ampicillin. Ampicillin is a β-lactam antibiotic, a semi-synthetic penicillin.

Metronidazole acetic acid, a mutagenic metabolite of an antibiotic, targets protozoa and anaerobic bacteria.

Cefpiramide sodium (SM-1652; Wy-44635) is a Pseudomonas-active cephalosporin. It has a broad spectrum of antibacterial activity.

Sulfamonomethoxine D4: deuterium-labeled, long-acting antibacterial sulfonamide; blocks folic acid synthesis in blood kinetics.

Carindacillin sodium, orally active broad-spectrum antibiotic, hydrolyzes to Carbenicillin, used in urinary tract infection studies.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Triclosan-methyl, derived from bactericidal triclosan, is used in toothpaste, shampoos, soaps, detergents, and cosmetics.

Oxacillin sodium monohydrate (Stapenor monohydrate) is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

Omeprazole D3 is deuterium labeled Omeprazole. Omeprazole is a proton pump inhibitor (PPI)

Sarafloxacin-d8 Hydrochloride is a deuterated compound of Sarafloxacin Hydrochloride. Sarafloxacin Hydrochloride has a CAS number of 91296-87-6. Sarafloxacin hydrochloride, a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.

Sulfamerazine D4 is deuterium-labeled, a sulfonamide that blocks bacterial folic acid production by binding instead of PABA.

Cefepime dihydrochloride: fourth-gen cephalosporin, inhibits bacterial PBPs.

Ofloxacin-d3 is a deuterated compound of Ofloxacin.

Acyclovir sodium is an antimetabolite. Acyclovir sodium inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis.

N,N',N''-Triacetylchitotriose is a competitive inhibitor of lysozyme.

Antibiotic-5d is a synthetic antimicrobial compound.

Cefozopran hydrochloride (SCE-2787 hydrochloride) is a fourth-generation cephalosporin.

Sulfapyridine (Standard) is the standard substance of Sulfapyridine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfapyridine (2-Sulfapyridine) is a short-acting sulfonamide antibiotic and by-product of the non-steroidal anti-inflammatory drug sulfasalazine.

Exo2 is a secretion inhibitor that disrupts trans-Golgi network (TGN) and interferes with the delivery of Shiga toxin to the endoplasmic lumen,.

Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections.

Sulfapyridine D4 a deuterium labeled Sulfapyridine. Sulfapyridine is a agent of sulfonamide antibacterial.

Chlorhexidine diacetate (Standard) is the standard substance of Chlorhexidine diacetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Lactoferrin (17-41) (Standard) is a reference material for analytical use. Lactoferrin (17-41) exhibits broad-spectrum antimicrobial activity.

Nitrofurazone (Standard) is the standard substance of Nitrofurazone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrofurazone (Nitrofural; Furacilin) is an orally active nitroaromatic broad-spectrum antibiotic with activity against both Gram-positive and Gram-negative bacteria. It is commonly used for establishing breast cancer models.

Etoposide Phosphate is a selective and orally active topoisomerase II inhibitor and anticancer chemotherapy drug that apoptosise, the p53, and G2/M

Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.

Temocillin disodium (BRL 17421 disodium) is a carbapenem antibiotic with antimicrobial activity and can be used to study urinary tract infections.

Gloxazone is an effective anaplasmacide with toxicity.

Spectinomycin sulfate hydrate is a broad-spectrum antibiotic capable of inhibiting the growth of various Gram-positive and Gram-negative bacteria. It targets bacterial ribosomes specifically, thereby disrupting protein synthesis. Additionally, spectinomycin sulfate hydrate acts as a non-competitive inhibitor of td intron RNA, with a Ki of 7.2 mM.

Chlorhexidine digluconate is a disinfectant with antibacterial activity that induces apoptosis and can be used to study bacterial infections.

Penicillin G procaine hydrate is to release the drug slowly and alleviate pain, with inhibitory activity against Gram-positive bacteria.

Duramycin, a cyclic peptide from Streptomyces, targets PE, offering antibacterial and antiviral properties, and may treat cystic fibrosis.