HBV
Os inibidores do HBV são compostos projetados para atingir e inibir várias etapas do ciclo de vida do vírus da hepatite B (HBV). Esses inibidores podem interferir na replicação, montagem ou liberação viral, reduzindo assim a carga viral e ajudando a gerenciar infecções crônicas por HBV. A pesquisa sobre inibidores do HBV é crucial para o desenvolvimento de terapias antivirais eficazes para prevenir doenças hepáticas e câncer associados ao HBV. Na CymitQuimica, oferecemos uma variedade de inibidores do HBV para apoiar sua pesquisa em virologia, desenvolvimento de medicamentos antivirais e controle de doenças infecciosas.
Foram encontrados 177 produtos de "HBV"
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BAY39-5493
CAS:BAY39-5493 is a hepatitis B virus inhibitor and possess antiviral activity in vitro and in vivo.Fórmula:C17H15ClFN3O2SCor e Forma:SolidPeso molecular:379.84LP10
CAS:<p>LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.</p>Fórmula:C24H28N4O2Cor e Forma:SolidPeso molecular:404.5Rolicyprine
CAS:<p>Rolicyprine is an antidepressant.</p>Fórmula:C14H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:244.29trans-ccc_R08
CAS:<p>trans-ccc_R08: potent cccDNA inhibitor, IC50 0.08 µM, may help research HBV.</p>Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84HBV-IN-29
CAS:<p>HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.</p>Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84KKJ00626
CAS:<p>KKJ00626, an inhibitor of HBV virus, inhibits HBV replication in transfected Huh7 cells.</p>Fórmula:C7H8N4SPureza:98%Cor e Forma:SolidPeso molecular:180.23HBV-IN-19
CAS:<p>HBV-IN19 suppresses HBV, cutting HBsAg output, useful for chronic HBV study.</p>Fórmula:C24H30N2O6Cor e Forma:SolidPeso molecular:442.5HBV-IN-25
CAS:<p>HBV-IN-25: oral HBV cccDNA reducer, anti-HBeAg, anti-HBV (IC50: 0.58/1.15 μM), soluble (>452 μg/mL), non-toxic.</p>Fórmula:C18H14ClNO4Cor e Forma:SolidPeso molecular:343.76Selgantolimod
CAS:Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.Fórmula:C14H20FN5OPureza:98%Cor e Forma:SolidPeso molecular:293.34Inarigivir
CAS:Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.Fórmula:C20H26N7O10PSPureza:98%Cor e Forma:SolidPeso molecular:587.5Z060228
CAS:Z060228 is a potent anti-HBV agent, halts HBV DNA replication, and disrupts Cp149 self-assembly.Fórmula:C20H15ClF4N2O2Pureza:98%Cor e Forma:SolidPeso molecular:426.79Alamifovir
CAS:<p>Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.</p>Fórmula:C19H20F6N5O5PSCor e Forma:SolidPeso molecular:575.42(5S,8R)-HBV-IN-10
CAS:<p>'(5S,8R)-HBV-IN-10 is an EC50 0.1-1 μM HBsAg inhibitor, isomer of compound 6 from patent WO2021204258A1.</p>Fórmula:C23H24FN7OCor e Forma:SolidPeso molecular:433.48Helioxanthin derivative 5-4-2
CAS:<p>Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.</p>Fórmula:C20H13NO5Pureza:99.91% - 99.92%Cor e Forma:SolidPeso molecular:347.32Fosclevudine alafenamide
CAS:<p>Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent that acts against HBV (EC50: 1.71 μM).</p>Fórmula:C22H29FN3O9PCor e Forma:SolidPeso molecular:529.45Taribavirin hydrochloride
CAS:<p>Taribavirin HCl: oral drug targeting HCV in liver, spares red blood cells, aims to reduce anemia risk.</p>Fórmula:C8H14ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:279.68Helioxanthin 8-1
CAS:<p>Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.</p>Fórmula:C20H12N2O6Pureza:98%Cor e Forma:SolidPeso molecular:376.32(-)-5′-Noraristeromycin
CAS:<p>(-)-5′-Noraristeromycin is an antiviral agent.</p>Fórmula:C10H13N5O3Cor e Forma:SolidPeso molecular:251.24RIG-1 modulator 1
CAS:RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.Fórmula:C14H17N5OS2Pureza:98%Cor e Forma:SolidPeso molecular:335.45BA38017
CAS:<p>BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].</p>Fórmula:C15H11ClFNO3Cor e Forma:SolidPeso molecular:307.7Taribavirin
CAS:<p>Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.</p>Fórmula:C8H13N5O4Pureza:98%Cor e Forma:SolidPeso molecular:243.22Bay 41-4109 (less active enantiomer)
CAS:<p>Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).</p>Fórmula:C18H13ClF3N3O2Pureza:98%Cor e Forma:SolidPeso molecular:395.76Bentysrepinine
CAS:Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.Fórmula:C29H35N3O4Pureza:98%Cor e Forma:SolidPeso molecular:489.61HBV-IN-10
CAS:<p>HBV-IN-10, an isomer of compound 6, inhibits HBsAg with EC50 between 0.1-1 μM (Patent WO2021204258A1).</p>Fórmula:C23H24FN7OCor e Forma:SolidPeso molecular:433.48NVP018
CAS:<p>NVP018 (BC 556) inhibits HBV, HCV, HIV-1 replication, barely affects drug transporters, and resists HCV/HIV-1 resistance development.</p>Fórmula:C45H62FN5O11Cor e Forma:SolidPeso molecular:868DVR-01
CAS:<p>DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.</p>Fórmula:C20H23ClN2O3SPureza:99.95%Cor e Forma:SolidPeso molecular:406.93Clevudine triphosphate
CAS:<p>Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate.</p>Fórmula:C10H16FN2O14P3Pureza:98%Cor e Forma:SolidPeso molecular:500.16Lagociclovir
CAS:<p>Lagociclovir (MIV-210), a nucleoside analogue antiviral, treats HBV by inhibiting its replication in liver cancer cells.</p>Fórmula:C10H12FN5O3Pureza:99.18% - 99.33%Cor e Forma:SolidPeso molecular:269.23Bay 41-4109
CAS:BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).Fórmula:C18H13ClF3N3O2Cor e Forma:SolidPeso molecular:395.76HBV-IN-9
CAS:<p>HBV-IN-9 inhibits HBsAg (IC50: 10 nM) and HBV DNA replication (IC50: 0.15 nM) per WO2018001952A1.</p>Fórmula:C22H24FN7OCor e Forma:SolidPeso molecular:421.47BA-53038B
CAS:BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).Fórmula:C14H16ClNOCor e Forma:SolidPeso molecular:249.74HBV-IN-6
CAS:<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).</p>Fórmula:C23H21ClFN3O5S2Cor e Forma:SolidPeso molecular:538.01Vidarabine phosphate
CAS:Vidarabine phosphate is an adenosine monophosphate analog.Fórmula:C10H14N5O7PPureza:99.75%Cor e Forma:White Crystalline PowderPeso molecular:347.22HBV-IN-32
CAS:<p>HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.</p>Fórmula:C22H19ClO5SCor e Forma:SolidPeso molecular:430.9L-Fd4A
CAS:<p>L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.</p>Fórmula:C10H10FN5O2Cor e Forma:SolidPeso molecular:251.22AB-506
CAS:<p>AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.</p>Fórmula:C21H18ClF2N5O3Cor e Forma:SolidPeso molecular:461.85cis-ccc_R08
CAS:<p>cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .</p>Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84Besifovir PM
<p>Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B</p>Fórmula:C11H15N5OPureza:98.48% - 99.90%Cor e Forma:SoildPeso molecular:233.27Pradefovir
CAS:<p>Pradefovir (Remofovir) is a prodrug for chronic HBV, converting to PMEA in the liver with a Km of 60 μM and clearance of 359 ml/min.</p>Fórmula:C17H19ClN5O4PPureza:97.50%Cor e Forma:SolidPeso molecular:423.79Bersacapavir
CAS:<p>Bersacapavir (JNJ-56136379) is an in vitro modulator of hepatitis B virus capsid assembly that inhibits HBV replication.</p>Fórmula:C16H14F4N4O3SPureza:98.53%Cor e Forma:SolidPeso molecular:418.37Tivicilovir
CAS:Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.Fórmula:C9H13N5O3Pureza:99.94%Cor e Forma:SolidPeso molecular:239.23Isothiafludine
CAS:<p>Isothiafludine is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells.</p>Fórmula:C18H18FN3OS2Pureza:99.71%Cor e Forma:SolidPeso molecular:375.48Valtorcitabine dihydrochloride
CAS:<p>Valtorcitabine dihydrochloride, a DNA polymerase inhibitor, is used potentially for the treatment of HBV infection.</p>Fórmula:C14H24Cl2N4O5Cor e Forma:SolidPeso molecular:399.27HBF-0259
CAS:HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Fórmula:C16H12Cl2FN5Pureza:98.07% - 99.42%Cor e Forma:SolidPeso molecular:364.2HBV-IN-13
CAS:<p>HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).</p>Fórmula:C22H25NO7Cor e Forma:SolidPeso molecular:415.44HEC72702
CAS:<p>HEC72702: New HBV capsid inhibitor, from GLS4. No CYP1A2, CYP3A4, CYP2B6 induction at 10μM.</p>Fórmula:C24H26BrFN4O5SCor e Forma:SolidPeso molecular:581.45HBV-IN-17
CAS:<p>HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM).</p>Fórmula:C17H15F6N5O2Cor e Forma:SolidPeso molecular:435.32Oxynitidine
CAS:<p>Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].</p>Fórmula:C21H17NO5Pureza:98%Cor e Forma:SolidPeso molecular:363.36HBV-IN-41
CAS:<p>HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].</p>Fórmula:C18H19ClFN5O3Pureza:98%Cor e Forma:SolidPeso molecular:407.83Emtricitabine triphosphate tetrasodium salt
CAS:<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Fórmula:C8H9FN3Na4O12P3SPureza:98%Cor e Forma:SolidPeso molecular:575.11
