HBV
Os inibidores do HBV são compostos projetados para atingir e inibir várias etapas do ciclo de vida do vírus da hepatite B (HBV). Esses inibidores podem interferir na replicação, montagem ou liberação viral, reduzindo assim a carga viral e ajudando a gerenciar infecções crônicas por HBV. A pesquisa sobre inibidores do HBV é crucial para o desenvolvimento de terapias antivirais eficazes para prevenir doenças hepáticas e câncer associados ao HBV. Na CymitQuimica, oferecemos uma variedade de inibidores do HBV para apoiar sua pesquisa em virologia, desenvolvimento de medicamentos antivirais e controle de doenças infecciosas.
Foram encontrados 170 produtos para "HBV".
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DVR-01
CAS:DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.Fórmula:C20H23ClN2O3SPureza:99.95%Cor e Forma:SolidPeso molecular:406.93Ref: TM-T27221
1mg109,00€5mg235,00€1mL*10mM (DMSO)265,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€L-Fd4A
CAS:L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.Fórmula:C10H10FN5O2Cor e Forma:SolidPeso molecular:251.22BA-53038B
CAS:BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).Fórmula:C14H16ClNOCor e Forma:SolidPeso molecular:249.74NVP018
CAS:NVP018 (BC 556) inhibits HBV, HCV, HIV-1 replication, barely affects drug transporters, and resists HCV/HIV-1 resistance development.Fórmula:C45H62FN5O11Cor e Forma:SolidPeso molecular:868Bentysrepinine
CAS:Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.Fórmula:C29H35N3O4Pureza:98%Cor e Forma:SolidPeso molecular:489.61(-)-5′-Noraristeromycin
CAS:(-)-5′-Noraristeromycin is an antiviral agent.Fórmula:C10H13N5O3Cor e Forma:SolidPeso molecular:251.24Alamifovir
CAS:Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.Fórmula:C19H20F6N5O5PSCor e Forma:SolidPeso molecular:575.42trans-ccc_R08
CAS:trans-ccc_R08: potent cccDNA inhibitor, IC50 0.08 µM, may help research HBV.Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84HBV-IN-7
CAS:HBV-IN-6 is a potent inhibitor of HBV (EC50: 5 nM).Fórmula:C18H17ClFN3O5S2Cor e Forma:SolidPeso molecular:473.93HBV-IN-9
CAS:HBV-IN-9 inhibits HBsAg (IC50: 10 nM) and HBV DNA replication (IC50: 0.15 nM) per WO2018001952A1.Fórmula:C22H24FN7OCor e Forma:SolidPeso molecular:421.47BA38017
CAS:BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].Fórmula:C15H11ClFNO3Cor e Forma:SolidPeso molecular:307.7Bay 41-4109 (less active enantiomer)
CAS:Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).Fórmula:C18H13ClF3N3O2Pureza:98%Cor e Forma:SolidPeso molecular:395.76HBV-IN-6
CAS:HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).Fórmula:C23H21ClFN3O5S2Cor e Forma:SolidPeso molecular:538.01AB-506
CAS:AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.Fórmula:C21H18ClF2N5O3Cor e Forma:SolidPeso molecular:461.85(5S,8R)-HBV-IN-10
CAS:'(5S,8R)-HBV-IN-10 is an EC50 0.1-1 μM HBsAg inhibitor, isomer of compound 6 from patent WO2021204258A1.Fórmula:C23H24FN7OCor e Forma:SolidPeso molecular:433.48HBV-IN-29
CAS:HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84HBV-IN-10
CAS:HBV-IN-10, an isomer of compound 6, inhibits HBsAg with EC50 between 0.1-1 μM (Patent WO2021204258A1).Fórmula:C23H24FN7OCor e Forma:SolidPeso molecular:433.48HBV-IN-32
CAS:HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.Fórmula:C22H19ClO5SCor e Forma:SolidPeso molecular:430.9cis-ccc_R08
CAS:cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .Fórmula:C22H19ClO6Cor e Forma:SolidPeso molecular:414.84HBV-IN-25
CAS:HBV-IN-25: oral HBV cccDNA reducer, anti-HBeAg, anti-HBV (IC50: 0.58/1.15 μM), soluble (>452 μg/mL), non-toxic.Fórmula:C18H14ClNO4Cor e Forma:SolidPeso molecular:343.76
