gsk-3
Os inibidores da GSK-3 são compostos que alvo a Glicogênio Sintase Quinase 3 (GSK-3), uma enzima envolvida em numerosos processos celulares, incluindo o metabolismo do glicogênio, a transcrição genética e a proliferação celular. A GSK-3 está implicada em várias doenças, como diabetes, distúrbios neurodegenerativos e câncer. Os inibidores da GSK-3 são ferramentas importantes para explorar essas vias e desenvolver potenciais terapias. Na CymitQuimica, oferecemos inibidores da GSK-3 para apoiar sua pesquisa em doenças metabólicas, neurobiologia e oncologia.
Foram encontrados 109 produtos de "gsk-3"
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GSK3β-IN-2
CAS:GSK3β-IN-2 (Compound S01) is an inhibitor of GSK3β with an IC50 of 0.35 nM. It activates the Wnt/β-catenin signaling pathway, promoting neurogenesis and neurite outgrowth. GSK3β-IN-2 reduces tau protein phosphorylation induced by Aβ at the Ser396 site, thereby decreasing neurofibrillary tangles. Furthermore, GSK3β-IN-2 improves Alzheimer's disease symptoms in a zebrafish model.Fórmula:C25H18N4OCor e Forma:SolidPeso molecular:390.437GSK-3β inhibitor 26
CAS:GSK-3β inhibitor26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. This compound is applicable in research related to cancer, inflammation, and neurodegenerative diseases.Fórmula:C15H11N3O3Cor e Forma:SolidPeso molecular:281.2665-Bromo-3-indoxylacetate
CAS:5-Bromo-3-indoxylacetate acts as an inhibitor of GSK-3, with a pIC50 value of 3.39.Fórmula:C10H8BrNO2Cor e Forma:SolidPeso molecular:254.08GSK-3β inhibitor 25
CAS:GSK-3β inhibitor25 (Compound 6h) exhibits weak inhibitory activity against GSK-3β with an IC50 greater than 100 μM.Fórmula:C16H15NOSCor e Forma:SolidPeso molecular:269.361GSK-3β inhibitor 20
CAS:GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.Fórmula:C22H21N5O2SCor e Forma:SolidPeso molecular:419.50GSK3-IN-9
CAS:GSK3-IN-9 (0713) is a selective inhibitor of glycogen synthase kinase 3 (GSK3). It holds potential for research into fragile X syndrome, attention deficit hyperactivity disorder (ADHD), childhood epilepsy, intellectual disabilities, diabetes, acute myeloid leukemia (AML), autism, and mental disorders.Fórmula:C18H20N4OCor e Forma:SolidPeso molecular:308.378GSK-3β inhibitor 7
GSK-3β inhibitor 7 is a GSK-3β inhibitor (IC50: 5.25 μM).Fórmula:C27H23BrN4O2SCor e Forma:SolidPeso molecular:547.47GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM.Fórmula:C20H17BrN4Cor e Forma:SolidPeso molecular:393.28Bisindolylmaleimide I HCl
CAS:Bisindolylmaleimide I HCl is a specific ATP-competitive PKC inhibitor.Fórmula:C25H25ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:448.95
