AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 168 produtos de "AMPK"
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AMPK activator 6
CAS:<p>AMPK activator 6 stimulates AMPK, lowers lipids in cells, and reduces serum TC, LDL-C, and TG. Useful for NAFLD and metabolic research.</p>Fórmula:C25H28O5Cor e Forma:SolidPeso molecular:408.49XMD-17-51
CAS:XMD-17-51 has DCLK1 kinase inhibitory activity, inhibits DCLK1 and cell proliferation, and can be used in lung cancer research.Fórmula:C21H24N8OPureza:99.04%Cor e Forma:SoildPeso molecular:404.47PF-739
CAS:PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.Fórmula:C23H23ClN2O5Pureza:98%Cor e Forma:SolidPeso molecular:442.89YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Fórmula:C21H21FN2OPureza:98%Cor e Forma:SolidPeso molecular:336.4DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Fórmula:C16H8ClF6N3OPureza:99.63%Cor e Forma:SolidPeso molecular:407.7YLF-466D
CAS:YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation.Fórmula:C29H20ClNO3Pureza:97.74%Cor e Forma:SolidPeso molecular:465.93PF-249
CAS:PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.Fórmula:C17H16ClN3O3Pureza:97.01%Cor e Forma:SolidPeso molecular:345.78MRT199665
CAS:MRT199665, a selective MARK/SIK/AMPK inhibitor, blocks SIK CRTC3 S370 phosphorylation and triggers apoptosis in AML cells.Fórmula:C28H31N5O2Cor e Forma:SolidPeso molecular:469.58Butylate
CAS:Butylate is a herbicide of thiocarbamate.Fórmula:C11H23NOSCor e Forma:Less Liquid Which Darkens Upon Exposure To Light Air And Moisture Colorless Liquid Which Darkens Upon Exposure To Light Air And MoisturePeso molecular:217.37ZLN024
CAS:<p>ZLN024 is an activator of AMPK allosteric.</p>Fórmula:C13H13BrN2OSPureza:99.751%Cor e Forma:SolidPeso molecular:325.22MARK-IN-1
CAS:<p>MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor, (IC50<0.25 nM).</p>Fórmula:C22H23F2N7OSPureza:98%Cor e Forma:SolidPeso molecular:471.53AMPK-α1β1γ1 activator 1
CAS:AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1Fórmula:C25H24ClNO9Pureza:98%Cor e Forma:SolidPeso molecular:517.91Demethyleneberberine chloride
CAS:Demethyleneberberine chloride, a natural mitochondria-targeted antioxidant, mitigates colitis in mice and suppresses inflammatory responses by blocking the NF-Fórmula:C19H18ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:359.8Ampkinone
CAS:Ampkinone is an indirect AMPK activator.Fórmula:C31H23NO6Pureza:98%Cor e Forma:SolidPeso molecular:505.52MARK-IN-2
CAS:MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor,(IC50:5 nM).Fórmula:C18H18ClF2N5OSPureza:98%Cor e Forma:SolidPeso molecular:425.88PF-06679142
CAS:PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.Fórmula:C20H17F2NO3Pureza:98%Cor e Forma:SolidPeso molecular:357.35AMPK-IN-1
CAS:AMPK-IN-1 is an activator of the AMP-activated protein kinase (AMPK) enzyme, specifically targeting the α2β2γ1 isoform with an EC50 of 551 nM.Fórmula:C24H18ClN3O3Cor e Forma:SolidPeso molecular:431.8710Z-Hymenialdisine
CAS:Pan kinase inhibitorFórmula:C11H10BrN5O2Pureza:98%Cor e Forma:Light Yellow SolidPeso molecular:324.13MK-0626
CAS:MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor enhancing AMP, restoring the expression of GLP-1R. promoting neoangiogenesis.Fórmula:C22H24F2N6O2Pureza:99.47% - >99.99%Cor e Forma:SolidPeso molecular:442.46AMPK activator 7
CAS:<p>AMPK activator 7 (I-3-24, EC50: 8.8 nM) targets AMPK-related disorders like type 2 diabetes and obesity.</p>Fórmula:C23H22F3N3O5Cor e Forma:SolidPeso molecular:477.43
