Oligossacarídeos

<p>Tetragalacturonic acid (α-1,4 galacturonotetraose) is derived from pectin or pectic acid by enzymatic or partial acid hydrolysis (Combo, 2012). It is used in galacturonic acid metabolism research as a substrate to identify, differentiate, and characterize endo- and exopolygalacturonase(s), and gluconase(s) (Jayani, 2005). The addition of very short fragments of homogalacturonan, tri-galacturonate, and tetra-galacturonate oligosaccharides restores development in dark-grown, de-etiolated seedling mutants, suggesting that they are unable to generate de-methylesterified pectin fragments. A model of spatiotemporally separated photoreceptive and signal-responsive cell types has been proposed, that contains overlapping subsets of the regulatory network of light-dependent seedling development (Sinclair, 2017).</p>

<p>Globotriaosylsphingosine is dramatically increased in plasma of classically affected male Fabry patients and plasma and tissues of Fabry mice. Globotriaosylsphingosine was shown to be an inhibitor of α-galactosidase A activity. Furthermore, exposure of smooth muscle cells, but not fibroblasts, to globotriaosylsphingosine at concentrations observed in plasma of patients promotes proliferation. It was suggested that measurement of circulating globotriaosylsphingosine would be useful to monitor Fabry disease and may contribute to a better understanding of the disorder.</p>

<p>Sialyllactose-BSA is a complex carbohydrate that is used in the synthesis of saccharides. It has been modified with fluorination to create a 6'-sialyllactose-BSA, which is a monosaccharide. This product can be custom synthesized and it's purity is high. The product can be methylated or glycosylated, and it has been click-modified for fluorescence labeling.</p>

<p>Core antigen fragment in ABO blood group system</p>

Globotriose-sp-biotin is a custom synthesis that contains a fluorinated, methylated, and modified monosaccharide. It is a synthetic oligosaccharide with glycosylation at the reducing end. Globotriose-sp-biotin can be used in the modification of polysaccharides and complex carbohydrates to improve their bioactivity. This product has a CAS number of 127798-73-5 and is listed as an Oligosaccharide under Glycosylations in the Carbohydrate section.

<p>Maltotridecaose is a sugar alcohol with an acceptor group that can be introduced into a cavity in a molecule. It is a sweetener that has been shown to have oligosaccharide properties, which are the molecules that comprise dietary carbohydrates. Maltotridecaose can be found as an unlabeled ingredient in foods such as sugar-free chewing gum, chocolate, and ice cream. The debranching of maltotridecaose occurs by way of glucans and licheniformis.</p>

<p>3'-b-Sialyl-N-acetyllactosamine is an oligosaccharide that is synthesized from L-arabinose and 3'-phosphoadenosine 5'-phosphosulfate. It has a high degree of purity and is custom synthesized to order. The CAS number for this product is 210418-18-1.</p>

<p>In plants and algae, the two main galactolipids, monogalactosyldiacyglycerol (MGDG) and digalactosyldiacyglycerol (DGDG), are synthesized by galactosyltransferases in the plastid envelope. They have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO)</p>

<p>2-AB labeled core pentasaccharide found in most N-linked oligosaccharides.  Purified from the oligosaccharide pool released from bovine serum by hydrazinolysis using a combination of HPLC and glycosidase digestion.</p>

<p>Cellulose derivative, food thickener and emulsifier, bulk forming laxative</p>

<p>Heparin derived disaccharide sodium salt is a salt form of heparin. It is a heterogenous mixture of low molecular weight compounds that are composed of sugar residues and sulfation. Heparin derived disaccharide sodium salt has been used for the treatment of thrombocytopenic purpura, thrombotic thrombocytopenic purpura, and other bleeding disorders. This drug also has been used to prevent blood coagulation in patients undergoing surgery.</p>

<p>Trehalose 6-octanoate is a modified form of trehalose that has been synthesized and fluorinated. It is a monosaccharide, which means it is one of the simplest forms of sugar. Trehalose 6-octanoate is an oligosaccharide, which means it is a sugar molecule made up of several smaller sugar molecules. This sugar can be modified to include methyl groups, making it a polysaccharide. Polysaccharides are complex carbohydrates that can often be found in plants or animals. Trehalose 6-octanoate is used in the modification of proteins and lipids for the production of pharmaceuticals and other products.</p>

<p>Neutral pentasasaccharide naturally present in human breast milk</p>

<p>Monofucosyllacto-N-hexaose II is a tetraol that is used as a reagent in the synthesis of enantioenriched and synthetically tetrasaccharidic products. Monofucosyllacto-N-hexaose II can be obtained by the reaction of Grignard reagents with glucose or by stereoselective reduction of an alpha, beta unsaturated ketone. The presence of the glucose residue in Monofucosyllacto-N-hexaose II makes it an acceptor for esterification reactions. This compound has chiral centers due to its two stereogenic centers at C2 and C3, which are both beta positions on the glucose residue. Monofucosyllacto-N-hexaose II also has a free hydroxyl group at C5 that can be esterified to produce chiral esters.</p>

<p>6-Deoxy-6-mercapto-gamma-cyclodextrin, octakis (Methyl 6DG) is a novel and unique sugar with two methyl groups on the C6 hydroxyl position. It has been synthesized from glucose by a click modification reaction and can be used as an alternative to 6DG for the production of oligosaccharides and polysaccharides. The high purity of Methyl 6DG makes it suitable for use in analytical research, such as fluorescence resonance energy transfer measurements.</p>

Difucosyl-para-lacto-N-hexaose II is a blood group oligosaccharide

<p>8-methoxycarbonyl ester of Gal-a1-3(Fuc-a1-2)Gal</p>

Safflor Yellow A is a natural drug that has been shown to have hypoglycemic effects. It is a potent inhibitor of glucose-6-phosphatase and glucose-6-phosphate dehydrogenase, which are enzymes involved in the conversion of glucose to glycogen. Safflor Yellow A also inhibits neuronal death, as it blocks the enzyme activities that lead to neuronal cell death. This drug has also shown antitumor activity, as it induces apoptosis in tumor cells. Safflor Yellow A also has antihyperlipidemic effects and can be used for the treatment of coronary heart disease. Low doses of this drug have been shown to reduce systolic pressure in rats and improve blood coagulation. The mechanism of action for this drug is not yet known but may involve toll-like receptor 4 signaling pathways or polymerase chain reaction (PCR).

<p>GalNAca1-3Galb1-3GalNAc</p>

<p>Trehalose 6-tetradecanoate is a custom synthesis of an oligosaccharide that is modified by methylation, glycosylation, and carbamylation. It is a polysaccharide that has been modified with click chemistry. Trehalose 6-tetradecanoate is a high purity product that can be used in the synthesis of other compounds.</p>