
Ligas Organometálicas
Subcategorias de "Ligas Organometálicas"
- Ligantes de Buchwald(22 produtos)
- DPEN(4 produtos)
- DPHEN(4 produtos)
- JOSIPHOS(4 produtos)
- Fosfina(497 produtos)
- Porfirinas(75 produtos)
Foram encontrados 2889 produtos de "Ligas Organometálicas"
Bafilomycin A1
CAS:Inhibitor of vacuolar-type proton pumpFórmula:C35H58O9Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:622.83 g/mol8-Deschloro-8-bromo-N-methyl desloratadine
CAS:Antagonist of platelet activating factorFórmula:C20H21BrN2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:369.3 g/molRolapitant hydrochloride monohydrate
CAS:Neurokinin-1 (NK-1) receptor antagonistFórmula:C25H27ClF6N2O2·H2OPureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:554.95 g/molBrimonidine-D-tartrate
CAS:Brimonidine-D-tartrate is a selective alpha-2 adrenergic agonist, which is a pharmacological compound derived synthetically, targeting specific receptor subtypes in the adrenergic receptor family. Its mode of action involves reducing aqueous humor production and increasing uveoscleral outflow in the eye, thereby lowering intraocular pressure. Additionally, it induces peripheral vasoconstriction, playing a role in reducing redness in rosacea.Fórmula:C15H16BrN5O6Cor e Forma:White PowderPeso molecular:442.22 g/molIndomethacin - Bio-X ™
CAS:Indomethacin is a nonsteroidal anti-inflammatory drug that inhibits the production of prostaglandin PGE2. It is used to treat pain, fever, and inflammation. Indomethacin's mechanism of action is not well understood, but it may be due to interference with the ability of PMNs to bind to the surface of bacteria or to release reactive oxygen species. The drug has been shown to reduce mitochondrial membrane potential in mammalian cells, leading to apoptosis. This effect on mitochondria may also contribute to Indomethacin's anti-inflammatory effects. Indomethacin is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C19H16ClNO4Pureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:357.79 g/molKenpaullone
CAS:Inhibitor of glycogen synthase 3 (GSK-3) and cyclin-dependent kinases CDK1, CDK2 and CDK5. Kenpaullone can substitute transcription factor Klf4 in reprogramming of fibroblast to induced pluripotent stem cells when using the method of ectopic expression of transcriptional factors. In an in vitro model for Alzheimer’s disease, kenpaullone decreased production of amyloid beta peptides Aβ40 and Aβ42.
Fórmula:C16H11BrN2OPureza:Min. 95%Cor e Forma:Yellow To Dark Yellow SolidPeso molecular:326.00548Ivacaftor
CAS:Activates CFTR channelsFórmula:C24H28N2O3Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:392.49 g/molRN 486
CAS:Bruton's tyrosine kinase antagonist; reduces Fcγ receptor signaling
Fórmula:C35H35FN6O3Pureza:Min. 95%Peso molecular:606.69 g/molNAcM-OPT
CAS:Inhibits N-Acetyl-mediated interaction between BE2M (E2 conjugating enzyme) and DCN1 (a component of E3 ligase complex). Also has inhibitory action on DCN2 and NEDD8 ubiquitin-like protein. Reduces anchorage-independent growth in DCN1-amplified cell line.Fórmula:C23H29Cl2N3OPureza:Min. 95%Cor e Forma:solid.Peso molecular:434.4 g/molEtelcalcetide hydrochloride
CAS:Agonist of calcium sensing receptor CASR; calcimimetic agentFórmula:C38H73N21O10S2·xHClPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:1084.71Interleukin-13 human
CAS:Interleukin-13 human is a recombinant cytokine, which is derived from the expression of the human IL-13 gene in suitable host systems, such as E. coli or mammalian cells. This cytokine belongs to the interleukin family and plays a pivotal role in the immune response by modulating inflammatory pathways. The mode of action of interleukin-13 involves binding to specific cell surface receptors, IL-13Rα1 and IL-13Rα2, which facilitates the activation of various intracellular signaling cascades, including the JAK/STAT pathway. This promotes the differentiation and proliferation of certain immune cells, influencing the production of IgE and contributing to the regulation of inflammatory responses.
Pureza:Min. 95%Benazepril HCl - Bio-X ™
CAS:Benazepril is a nonsteroidal anti-inflammatory drug that can be used to treat hypertension, heart failure and renal failure. It is an angiotensin-converting enzyme (ACE) inhibitor that blocks the conversion of angiotensin I to angiotensin II. This inhibition prevents the vasoconstrictive effects of this peptide, which are mediated through activation of the renin-angiotensin system.Fórmula:C24H28N2O5•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:460.95 g/molFingolimod HCl - Bio-X ™
CAS:Fingolimod is a sphingosine 1-phosphate receptor modulator that is used in the treatment of relapsing-remitting form of multiple sclerosis. It is also being studies to manage lung complications in patients with COVID-19. This drug binds to various sphingosine 1-phospahte receptors and suppresses the exit of lymphocytes from lymph nodes.Fórmula:C19H33NO2•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:343.93 g/molCHIR 99021
CAS:Potent and selective inhibitor of the glycogen synthase kinase GSK-3. Promotes cell renewal in embryonic stem cells by modulating Notch, MAPK and TGF-β signalling pathways, which are involved in pluripotency. It also affects the Wnt/β-catenin pathway and alters expression of genes coding for proteins, epigenetic regulatory elements and non-coding RNAs. The combination of CHIR 99021 and basic fibroblast growth factor (bFGF) allows long-term self-renewal in adult mouse retinal progenitor cells.Fórmula:C22H18Cl2N8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:465.34 g/molCamostat mesylate - Bio-X ™
CAS:Camostat is a serine protease inhibitor that is used for the treatment of chronic pancreatitis. This drug has shown to reduce inflammation and pain. Studies have shown that Camostat has also inhibited the entry of SARS-CoV-2 in lung cells by inhibiting the priming process of S-protein, necessary for the viral entry into host cells.Fórmula:C20H22N4O5•CH4O3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:494.52 g/molAMG 9810
CAS:Vanilloid receptor 1 antagonistFórmula:C21H23NO3Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:337.41 g/mol(Z)-Mycophenolic acid
CAS:(Z)-Mycophenolic acid is an immunosuppressive agent derived from the fermentation of fungi, primarily from the Penicillium species. It functions by inhibiting inosine monophosphate dehydrogenase (IMPDH), an enzyme crucial for de novo purine synthesis. This selective blockade of IMPDH specifically affects lymphocyte proliferation due to their heavy reliance on this pathway for DNA synthesis, thereby exerting its immunosuppressive effects.Fórmula:C17H20O6Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:320.34 g/molMalotilate - Bio-X ™
CAS:Malotilate is a pharmacological agent that is used to treat symptoms of hepatitis, bowel disease, and collagen diseases. This drug reduces collagen synthesis and cell migration activity of fibroblasts in vitro. It also has been shown to facilitate liver regeneration in rats.Fórmula:C12H16O4S2Pureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:288.39 g/molMNI-caged-L-glutamate
CAS:A light-sensitive probe that functionally encapsulates L-glutamate in an inactive form. Irradiation with light at 360-380 nm cleaves the MNI protecting group and allows the release of free L-glutamate. It allows tuneable control of the L-glutamate in neurons and precise control over time, dose and location of L-glutamate release.Fórmula:C14H17N3O6Pureza:Min. 95%Peso molecular:336.8 g/molNAP
CAS:NAP is a neuroprotective peptide, which is derived from activity-dependent neuroprotective protein (ADNP), with a mechanism involving microtubule stabilization and neuronal protection. It exhibits the ability to protect neurons from various types of damage, including oxidative stress and conditions mimicking neurodegenerative diseases. NAP enhances axonal transport and increases the resilience of neurons to insults that would typically result in cell death. This peptide has shown promise in preclinical studies for its potential to halt or reverse cognitive decline, making it a focal point for research into therapeutic strategies for disorders like Alzheimer's disease and other tauopathies. The peptide operates by binding to microtubules, promoting stability, and facilitating efficient transport of cellular components. Studies have highlighted its role in traversing the blood-brain barrier, which makes it a viable candidate for central nervous system-targeted therapies. Researchers continue to explore its efficacy and possible applications in improving cognitive function and providing neuroprotection in aging populations.Pureza:(Hplc-Ms) Min. 98 Area-%
