Outros inibidores

<p>Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.</p>

<p>PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.</p>

<p>OB-1 is a STOML3 inhibitor that interferes with the self-association of stomatin, inhibiting fat formation and blocking lipid droplet growth.</p>

<p>ELOVL1-IN-2 weakly inhibits ELOVL1 enzyme (IC50: 21 μM) and shows moderate potency in HEK293 cells (IC50: 6.7 μM).</p>

<p>NRX-1532 is a small molecule β-catenin:β-TrCP interaction enhancer.</p>

<p>YTH-IN-1 is an inhibitor of the five YTH structural domains in the human.The YTH family of proteins is an N 6-methyladenosine (m6A) reader in gene expression.</p>

<p>O-Propargyl-Puromycin (OP-puro) is a potent protein synthesis inhibitor, a puromycin acetylene analog.</p>

<p>Skp2 inhibitor 1 is a Skp2-Cks1 interaction inhibitor (IC50: 2.8μM) with antitumor activity and can be used to study cancer.</p>

<p>VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.</p>

<p>Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.</p>

<p>BLU2864: oral PRKACA inhibitor, IC50=0.3 nM, potential in cancer/poly. kidney disease research.</p>

<p>ARN19702: orally active, brain-penetrant, selective NAAA inhibitor, IC50 230 nM, broad analgesic profile.</p>

<p>Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases.</p>

<p>TEM1/CD248 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 73.6 kDa and the accession number is Q91V98.</p>

<p>Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.</p>

<p>L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.</p>

<p>BFCAs-1 is a polyamine polycarboxylic bifunctional chelating agent (BFCAs) with a broad range of applications in biology, chemistry, medicine and diagnostic imaging.</p>

<p>β-Zearalenol, a non-steroidal estrogenic mycotoxin synthesized by Fusarium species, potentially influences transcription and affects gene expression on the translational level.</p>

<p>SPL-410 is a highly potent,selective and orally active inhibitor of hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a)(IC50 of 9 nM).</p>

N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)

<p>Demethyl 8-Epidiosbulbin E acetate is a structural analog of 8-Epidiosbulbin E acetate, a furan analog found in Dioscorea bulbifera L. 8-Epidiosbulbin E acetate is a furan analog found in Dioscorea bulbifera L. It is a structural analog of 8-Epidiosbulbin E acetate.</p>

<p>TCblR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-58 KDa and the accession number is Q9NPF0.</p>

<p>sodium 4-pentynoate is a alkynylacetate analogue.</p>

<p>A-887826 is a selective, orally bioavailable, and voltage-dependent Na(v1.8) channel blocker (IC50: 11 nM). It attenuates neuropathic tactile allodynia in vivo.</p>

<p>Beraprost sodium is a stable and orally active prodrug of PGI2.</p>

<p>Calcitriol Impurities A refers to the contaminants found in Calcitriol, the hormonally active metabolite of vitamin D3, which serves to activate the vitamin D receptor.</p>

<p>BI-2545 is an autotaxin (ATX) inhibitor that significantly reduces LPA. For human ATX and rat ATX, the IC50s values are 2.2 nM and 3.4 nM , respectively.</p>

<p>Umbellulone is a natural product isolated from Umbellularia californica, and stimulates the TRPA1 channel in a subset of peptidergic, nociceptive neurons, activating the trigeminovascular system via this mechanism.</p>

<p>(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, a constrained phenylalanine (Phe) analogue, can adopt beta-bend and helical structures, thereby facilitating a preferred side-chain orientation within the peptide.</p>

<p>2-Selenouracil is a specialized photosensitizer for photodynamical therapy.</p>

<p>(8R,9S)-Talazoparib is Talazoparib enantiomer , less active than Talazoparib on the inhibition of PARP1 (IC50: 144 nM).</p>

β-Apo-13-carotenone is a naturally occurring β-apocarotenoid, and is a RXRα antagonist.

<p>GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. GAS6 Protein, Human, Recombinant (His) is expressed in HEK293 cells.</p>

<p>PF-06747711 is an effective and selective retinoic acid receptor-related orphan C2 inverse agonist (IC50: 4.1 nM). PF-06747711 also has anti-skin inflammatory activity.</p>

<p>4',5'-Dibromofluorescein (Eosinic acid) is a fluorescent dye that can be used as a ligand for protein characterization by spectroscopic analysis.</p>

<p>Daphnin is one of the main coumarin bioactive ingredients with antibacterial activity. Daphnine is isolated from the entire Daphne fragrance, which is a folk medicine used in China to relieve fever.</p>

<p>Metrizoic acid is an ionic contrast medium. Metrizoic acid displays high osmolality and has a risk of inducing allergic reactions.</p>

<p>CMK, an RSK2 kinase inhibitor, shows similar potency but less chemical stability compared with FMK.</p>

<p>Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-induced currents at the GABAA receptor, and can be used in the study of neurological disorders.</p>

<p>Endogenous fatty acid glycerol ester</p>

<p>Norbiotinamine, a biotin alternative, is a sulfur-containing organic compound with a structure similar to that of biotin.</p>

<p>Anisylacetone (Anisylacetone) is an effective lure for the male melon fly.</p>

<p>Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant.Cost-effective and quality-assured.</p>

<p>3-Methoxyphenylacetic acid belongs to the class of organic compounds known as anisoles. 3-Methoxyphenylacetic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa).3-Methoxyphenylacetic acid (m-Methoxyphenylacetic acid), a m-hydroxyphenylacetic acid (m-OHPAA) derivative, is a phytotoxin in Rhizoctonia solani. 3-Methoxyphenylacetic acid is used to develop a toxin-mediated bioassay for resistance to rhizoctonia root rot</p>

<p>Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH increased.</p>

<p>PRGL493 blocks ACSL4, halts PC3/MDA-MB-231 cancer cell spread, and inhibits MA-10 tumor progesterone. Effective in mouse PC3 tumor model at 0.25 mg/kg.</p>

<p>3-Acetylcoumarin as a practical ligand for copper-catalyzed CN coupling reactions at room temperature. It has neuroprotective and acaricidal properties.</p>

<p>4-Ethoxycoumarin has antimicrobial activity.</p>

<p>2-Methylbenzo[d]isothiazol-3(2H)-one is a useful organic compound for research related to life sciences. The catalog number is T67421 and the CAS number is 2527-66-4.</p>

<p>2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine, with catalog number T66608 and CAS number 90213-66-4, is a valuable organic compound for life sciences research.</p>

<p>Kartox, an insecticide, is a combination of and lindane &amp; cartap.</p>

<p>Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine is a useful organic compound for research related to life sciences. The catalog number is T66183 and the CAS number is 1160861-53-9.</p>

<p>1-Cyclopropyl-6,7-difluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T66948 and the CAS number is 112811-72-0.</p>

<p>9-Oxo-9H-fluorene-2,7-dicarboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67495 and the CAS number is 792-26-7.</p>

<p>1-Ethylpiperazine-2,3-dione is a useful organic compound for research related to life sciences. The catalog number is T67665 and the CAS number is 59702-31-7.</p>

<p>3,5-Pyridinedicarboxylic Acid is a useful organic compound for research related to life sciences. The catalog number is T66974 and the CAS number is 499-81-0.</p>

<p>Azido-PEG12-t-butyl ester, a soluble PEG with azide/reactive t-butyl, forms triazoles via Click Chemistry; deprotectable in acid.</p>

<p>N-(3-Chloro-4-hydroxyphenyl)acetamide is a useful organic compound for research related to life sciences. The catalog number is T67206 and the CAS number is 3964-54-3.</p>

<p>(1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a useful organic compound for research related to life sciences. The catalog number is T66857 and the CAS number is 79200-56-9.</p>

<p>5-Ethyluracil is a useful organic compound for research related to life sciences. The catalog number is T65967 and the CAS number is 4212-49-1.</p>

<p>2-(Piperidin-4-yl)-1H-benzo[d]imidazole is a useful organic compound for research related to life sciences. The catalog number is T66525 and the CAS number is 38385-95-4.</p>

<p>Guanylthiourea is a useful organic compound for research related to life sciences. The catalog number is T64909 and the CAS number is 2114-02-5.</p>

<p>Ves v 5 Protein, Vespula vulgaris, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.1 kDa.</p>

<p>2-((2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64717 and the CAS number is 2103656-92-2.</p>

<p>2-Chloroethyl palmitate is a useful organic compound for research related to life sciences. The catalog number is T66561 and the CAS number is 929-16-8.</p>

<p>2', 3'-cGAMP-C2-SH is a ADC cytotoxin.</p>

<p>3-((2-(2-Chlorophenyl)-2-hydroxyethyl)amino)-3-methylbutanoic acid is a useful organic compound for research related to life sciences. The catalog number is T64403 and the CAS number is 2172852-92-3.</p>

<p>Expression System: P. pastoris (Yeast)&lt;br&gt;Activity: Not Tested</p>

<p>Patent Blue V (Acid blue 1), a biological dye, serves as an intraocular stain in retinectomy—surgical removal of the inner limiting membrane (ILM).</p>

<p>1,4-Bis((4-chlorophenyl)(phenyl)methyl)piperazine dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T67082.</p>

<p>Cap-dependent endonuclease-IN-12 (EXP-35) is a potent inhibitor with low toxicity, active against H1N1.</p>

<p>Benzyl 2-(2-aminoacetamido)acetate 4-methylbenzenesulfonate, catalog number T65216 and CAS number 1738-82-5, is a valuable organic compound for life sciences research.</p>

<p>DiAzK has a wide range of applications in life science related research.</p>

<p>Tienoxolol is a molecule diuretic, natriuretic and P-adrenoceptor blocking properties. Furthermore, tienoxolol binds to Al and A2 adenosine receptors.</p>

<p>Biotin-PEG2-azide, a PEG-based PROTAC linker, can be used in the synthesis of PROTACs.</p>

<p>5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66095 and the CAS number is 720720-96-7.</p>

<p>Sodium 2-chloro-2,2-difluoroacetate is a useful organic compound for research related to life sciences. The catalog number is T66899 and the CAS number is 1895-39-2.</p>

<p>(2'-Methylamino-1,1'-biphenyl-2-yl)methanesulfonatopalladium(II) dimer is a useful organic compound for research related to life sciences and the catalog number is T67263.</p>

<p>4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile is a useful organic compound for research related to life sciences. The catalog number is T67635 and the CAS number is 103146-25-4.</p>

<p>1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide is a useful organic compound for research related to life sciences. The catalog number is T65742 and the CAS number is 139756-01-7.</p>

<p>Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels.</p>

<p>6-Desacetyl Palbociclib is a useful organic compound for research related to life sciences and the catalog number is T64486.</p>

<p>(11aR)-10,11,12,13-Tetrahydro-N,N-bis[(1R)-1-phenylethyl]diindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine is a useful organic compound for research related to life sciences and the catalog number is T66952.</p>

<p>Apratoxin A is a potent cytotoxin isolated from the marine cyanobacterium Lyngbya majuscula Harvey ex Gomont.</p>

<p>H2N-PEG2-CH2COOtBu is a useful organic compound for research related to life sciences and the catalog number is T64432.</p>

<p>(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate is a useful organic compound for research related to life sciences. The catalog number is T64602 and the CAS number is 1354823-36-1.</p>

<p>6-Chloropyrimidin-4-amine is a useful organic compound for research related to life sciences. The catalog number is T66144 and the CAS number is 5305-59-9.</p>

<p>1-Acetyl-4-methylpiperazine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67190 and the CAS number is 144205-68-5.</p>

<p>2,5-Diaminobenzoic acid is a useful organic compound for research related to life sciences. The catalog number is T67030 and the CAS number is 610-74-2.</p>

<p>1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea is a useful organic compound for research related to life sciences. The catalog number is T67700 and the CAS number is 1144075-47-7.</p>

<p>5-Chlorohexanoyl chloride is a useful organic compound for research related to life sciences. The catalog number is T64515 and the CAS number is 99585-01-0.</p>