Outros inibidores

TAT-PEG-Cy3 is a fluorescent labeling reagent that integrates the Cy3 fluorescent dye, a cell-penetrating peptide (TAT), and polyethylene glycol (PEG). The Cy3 fluorophore is commonly employed in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a maximum emission wavelength of approximately 562–570 nm. TAT-PEG-Cy3 is suitable for cell-targeted delivery and bioimaging.

Ceylantin is a natural product that can be used as a reference standard. The CAS number of Ceylantin is 68421-13-6.

<p>Eicosapentaenoic acid is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases.</p>

Formamide, N-(5-(p-aminophenoxy)pentyl)- is a bioactive chemical.

Jaceoside is a useful organic compound for research related to life sciences. The catalog number is T125193 and the CAS number is 25474-11-7.

<p>(+)-Goniothalesdiol, from G. borneensis bark, has anti-leukemic and pesticidal properties, with ED50 ≥30 μg/ml against P388.</p>

Mal-CO-PEG5-NHS ester is a 5-unit PEG-based, non-cleavable ADC linker utilized in the fabrication of antibody-drug conjugates (ADCs).

Cy5-Polystyrene microsphere (100 nm) is a Cy5-labeled microsphere utilized for bioimaging and drug delivery.

PAD2-IN-2 (cis-isomer of 1) TFA is an inhibitor of protein arginine deiminase 2 (PAD2). This molecule features an azobenzene photoswitch, enabling the optical regulation of PAD activity. Additionally, PAD2-IN-2 TFA inhibits the citrullination of histone H3.

1-Methyl-3-amino-4-cyanopyrazole (compound 3) is a molecule used in the synthesis of adenosine A3 receptor antagonists.

Filgotinib analogue isa a structurally analogue of Filgotinib and can be used in life science related research.

CAP 2 is an ionizable cationic lipid composed of two cholesterol units linked by a phosphate connector that includes an amino head group.

2N12B is an ionizable cationic lipid containing a disulfide bond (pKa = 6.5), utilized in the creation of lipid nanoparticles (LNPs) for the delivery of siRNA both in vitro and in vivo.

(ZE)-Farnesyl Pyrophosphate ammonium salt is an isomer of (E,E)-, metabolic intermediate in the mevalonatepathway and an agonist of TRPM2.

Schizokinen is a citrate-containing dihydroxamate and a siderophore produced by Bacillus megaterium and Anabaena sp.

m-((3-Amino-4-hydroxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

THR-β agonist 8 (Compound 1) is an orally active agonist for both TRα and TRβ. It holds potential for research into thyroid hormone-related diseases.

Sulfo-EGS: water-soluble, non-cell-permeable crosslinker for labeling cell surface proteins.

Pateclizumab (MLTA3698A) is a humanized monoclonal antibody targeting lymphotoxin α (LTα), which can be used to study rheumatoid arthritis.

Ezetimibe-d4-1 is the deuterated form of Ezetimibe, which functions as a potent cholesterol absorption inhibitor and NPC1L1 inhibitor, and also exhibits Nrf2 activation properties.

WWP1/2-IN-1 (compound 11) acts as an inhibitor for WWP1 and WWP2, with IC50 values of 32.7 µM and 269.2 µM, respectively.

D-Psicose is a naturally occurring compound reported in both Arabidopsis thaliana and Solanum lycopersicum.

Saurulignan A is a useful organic compound for research related to life sciences. The catalog number is T125753 and the CAS number is 1532522-50-1.

AT-584 is a bio-active chemical.

Benzo[c][1,2]oxaborole-1,5(3H)-diol is a useful organic compound for research related to life sciences.

Cgp 43902A is a bio-active chemical.

RC363, a probucol derivative, inhibits ferroptosis, reduces radicals by 40% at 25 μM, protects HT22 cells from glutamate toxicity, and boosts GPX activity.

Compound 12k (THP-1/MV-4-11 against-1) is a 5-substituted thiazolyl urea anticancer agent with significant inhibitory efficacy against THP-1/MV-4-11 cancer cells, demonstrating IC50 values of 29 nM and 98 nM, respectively.

IP6K2-IN-2 (Compound 6) is an inhibitor of IP6K2, with IC50 values of 0.58 μM, 0.86 μM, and 3.08 μM for IP6K2, IP6K1, and IP6K3, respectively. It is applicable in obesity research.

C9-200 is an ionizable cationic lipid employed in the formulation of lipid nanoparticles (LNPs).

HO-PEG-amine (MW 10000) is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker for the synthesis of PROTACs[1].

7α-Methoxy-5α,6α-epoxyergosta-8(14),22-dien-3β-ol is a natural product for research related to life sciences.

Salacetamide is a bioactive chemical.

Phenyl-glutarimide 4'-piperazine, a piperazine-functionalized cereblon ligand, facilitates the development of PG-PROTACs with enhanced hydrolytic stability and

Lithium Carmine is a macrophages stain.

Asante potassium green-1 (APG-1) TMA is a cell-impermeant fluorescent indicator for K+ (potassium ions), with excitation and emission maxima at 525/545 nm.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(diethylamino)ethyl)-, hydrochloride is a bioactive chemical.

Eschweilenol C is a useful organic compound for research related to life sciences and the catalog number is T125361.

Siderin, a Photosystem II inhibitor, effectively impedes ATP synthesis and chloroplast electron transport in photosynthesis within isolated spinach chloroplasts

<p>5-Chlorouracil is a chlorinated derivative of the pyrimidine nucleoside base uracil .</p>

Neocryptomerin is a useful organic compound for research related to life sciences and the catalog number is T125374.

Propylene glycol monostearate is a lipid ester formed by the connection of hydroxylated propylene glycol with the long-chain saturated fatty acid, stearic acid.

<p>19-Epivoacristine is a useful organic compound for research related to life sciences and the catalog number is T124389.</p>

Trans-2-Dodecenal（(2E)-dodec-2-enal） is an aldehyde compound with a strong citrus aroma, commonly used in flavors and food additives, organic synthesis.

Ginisortamab (MouseIgG1) is a monoclonal antibody targeting Gremlin-1, carried by Mouse IgG1. This compound is applicable in research focused on gastrointestinal (GI) tumors.

M-dimethylaminophenyl urea is a bioactive chemical.

3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) free acid is a TLR agonist that serves as a vaccine adjuvant to boost the immunogenicity of vaccines.

MTX-PEG-Cy3 is a Cy3-labeled MTX-PEG conjugate. Cy3 fluorophore is frequently utilized in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry, with a maximum emission wavelength of approximately 562-570 nm. Methotrexate (Amethopterin; MTX) serves as an antimetabolite and antifolate agent that inhibits dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolate and ultimately inhibiting DNA synthesis. Additionally, Methotrexate functions as an immunosuppressant and antineoplastic agent, deployed in the treatment of rheumatoid arthritis and the investigation of various cancers, including acute lymphoblastic leukemia.

LYS228 (also known as Ancremonam) is a potent antibiotic effective against carbapenem-resistant Enterobacteriaceae bacteria (MIC90 = 2 uM/mL). It demonstrates strong antibacterial activity against CRE isolates even in the presence of all classes of β-lactamases.

(E)-4-Dimethylamino-N-methylstilbazolium iodide (Py-NMe2) is a styrene-based dye employed in sensing various double-stranded DNA/RNA sequences using fluorescence and circular dichroism (CD) techniques. Its absorption maximum is 450 nm, and its emission maximum is 615 nm.