Outros inibidores

Carglumic Acid (Ureidoglutaric acid) is an orphan drug used to treat hyperammonemia in patients with N-acetyl glutamate synthase absence.

<p>Chlormadinone acetate (Gestafortin) is an orally active synthetic progestational hormone used often in combinations as an oral contraceptive.</p>

<p>Chromocarb (Chromone-2-carboxylic acid) is a vascular protective agent used to treat venous disorders and microvascular affections.</p>

Admire is an important compound in the study of pesticides in agriculture.

2OH-BNPP1 is a BUB1 kinase, a Ser/Thr kinase inhibitor, it used for the treatment of cancer.

TDI-011536: strong Lats kinase blocker, boosts heart cell growth, aids organ repair research.

<p>SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 μM in a rat liver microsomal assay, with antiinflammatory properties.</p>

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MT-RNR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MT-RNR2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human MT-RNR2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human MT-RNR2 in the samples is then determined by comparing the OD of the samples to the standard curve.

<p>4-Chloro-4'-hydroxybenzophenone: a tyrosinase inhibitor and antioxidant, prevents lipid/protein oxidation.</p>

Bococizumab (PF-04950615) is a humanized mAb that inhibits PCSK9, reducing blood LDL cholesterol to treat hypercholesterolemia.

<p>Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.</p>

<p>N-CBZ-Phe-Arg-AMC hydrochloride (N-CBZ-Phe-Arg-AMC hydrochloride) is a cysteine peptidase substrate that can be used to assess cysteine peptidase activity.</p>

Chlorobenzothiazolinone blocks human chymase at 90 μM, assessed by fluorescence using a specific peptide substrate after 1 hr.

C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research.

<p>Mequinol (Leucobasal) is a derivate of hydroquinone and depigmenting agent. Mequinol acts by oxidising tyrosinase in melanocytes to produce cytotoxic products.</p>

<p>Leucocrystal Violet is a triphenylmethane dye.</p>

<p>Iopamidol (SQ-13396) is a benzenedicarboxamide compound. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic.</p>

<p>Duvakitug (SAR-447189) is a humanized IgG1-λ2 monoclonal antibody targeting TNFSF15/TL1A, which can be used to study ulcerative colitis and Crohn's disease.</p>

<p>Bromindione (Fluidane) is a new anticoagulant.</p>