Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1381 produtos de "Sinalização Citoesquelética"
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NSC305787
CAS:<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Fórmula:C25H30Cl2N2OPureza:99.40%Cor e Forma:SolidPeso molecular:445.42Clathrin-IN-25
CAS:<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Fórmula:C19H13KNO5SCor e Forma:SolidPeso molecular:406.47BGB659
CAS:<p>BGB659 is effective inhibitor of RAF.</p>Fórmula:C29H29F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:538.56HR22C16
CAS:<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Fórmula:C23H23N3O3Cor e Forma:SolidPeso molecular:389.45CGP60474
CAS:<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Fórmula:C18H18ClN5OPureza:98.81%Cor e Forma:SolidPeso molecular:355.82DAT1
CAS:<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Fórmula:C17H15N3O2SPureza:98%Cor e Forma:SolidPeso molecular:325.38Shz 1
CAS:<p>Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.</p>Fórmula:C13H11BrN2O3SPureza:99.57% - 99.91%Cor e Forma:SolidPeso molecular:355.21GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Fórmula:C29H37N5O2Pureza:99.547%Cor e Forma:SolidPeso molecular:487.64BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Fórmula:C20H21O10PCor e Forma:SolidPeso molecular:452.3485YM-01 Tosylate
CAS:<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Fórmula:C27H27N3O4S3Cor e Forma:SolidPeso molecular:553.72Displurigen
CAS:<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Fórmula:C15H10O4SPureza:98%Cor e Forma:SolidPeso molecular:286.3NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Fórmula:C18H17NO2Pureza:98%Cor e Forma:SolidPeso molecular:279.33ML-243
CAS:<p>inhibitor of cancer stem cells</p>Fórmula:C14H16N2OSPureza:98%Cor e Forma:SolidPeso molecular:260.35Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Fórmula:C24H27N5O7Pureza:98%Cor e Forma:SolidPeso molecular:497.5AKT-IN-9
CAS:<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Fórmula:C24H29ClN6OCor e Forma:SolidPeso molecular:452.98D011-2120
CAS:<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Fórmula:C17H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:281.31JG-48
CAS:<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Fórmula:C20H16F3N3OS2Cor e Forma:SolidPeso molecular:435.49Mps-BAY2b
CAS:<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Fórmula:C20H23N5OCor e Forma:SolidPeso molecular:349.43PU24FCl
CAS:<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Fórmula:C20H21ClFN5O3Cor e Forma:SolidPeso molecular:433.86LDN-193665
CAS:LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Fórmula:C15H11FN4OSPureza:98%Cor e Forma:SolidPeso molecular:314.34BOP sodium
CAS:<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Fórmula:C25H29N3NaO7SCor e Forma:SolidPeso molecular:538.57Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Fórmula:C17H19N5O2Pureza:98%Cor e Forma:SolidPeso molecular:325.37Hydromethylthionine HBr
CAS:<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Fórmula:C16H21Br2N3SCor e Forma:SolidPeso molecular:447.233ZW4864 free base
CAS:<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Fórmula:C33H42N6O3Pureza:99.81%Cor e Forma:SolidPeso molecular:570.72Diazobenzenesulfonic acid
CAS:<p>Diazobenzenesulfonic acid, white/red crystal, inhibits myosin ATPase 13 as an allosteric desensitizer.</p>Fórmula:C6H5N2O3SPureza:98%Cor e Forma:SolidPeso molecular:185.18Box5
CAS:<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Fórmula:C30H50N6O13S2Cor e Forma:SolidPeso molecular:766.88CCT036477
CAS:<p>CCT036477 selectively inhibits Wnt/β-catenin signaling, reducing TCF/LEF transcriptional activity.</p>Fórmula:C21H18ClN3Pureza:98%Cor e Forma:SolidPeso molecular:347.84Acodazole hydrochloride
CAS:<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Fórmula:C20H20ClN5OPureza:98%Cor e Forma:SolidPeso molecular:381.86Tubulin polymerization-IN-37
CAS:<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Fórmula:C19H20N2O4Cor e Forma:SolidPeso molecular:340.37αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Fórmula:C28H35F3N6O8SPureza:98%Cor e Forma:SolidPeso molecular:672.67Cevipabulin
CAS:<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Fórmula:C18H18ClF5N6OPureza:99.53%Cor e Forma:SolidPeso molecular:464.82Anticancer agent 60
CAS:<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Fórmula:C27H33N5O4SCor e Forma:SolidPeso molecular:523.65ABH Hydrochloride
CAS:<p>ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.</p>Fórmula:C6H15BClNO4Cor e Forma:SolidPeso molecular:211.45Malonganenone A
CAS:<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Fórmula:C26H38N4O2Cor e Forma:SolidPeso molecular:438.61BMS-587101
CAS:<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Fórmula:C26H20Cl2N4O4SCor e Forma:SolidPeso molecular:555.43BMS-358233
CAS:<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Fórmula:C25H25ClN6O2SCor e Forma:SolidPeso molecular:509.02Acodazole
CAS:<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Fórmula:C20H19N5OPureza:98%Cor e Forma:SolidPeso molecular:345.4L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Fórmula:C24H34N4O4Pureza:98%Cor e Forma:SolidPeso molecular:442.55TCS 2314
CAS:<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Fórmula:C28H34N4O6Pureza:98%Cor e Forma:SolidPeso molecular:522.59KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Cor e Forma:SolidPeso molecular:574.76Hsp90-IN-17
CAS:<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Fórmula:C21H20N4O7Cor e Forma:SolidPeso molecular:440.41β-glycosidase-IN-1
CAS:<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Fórmula:C13H23NO5Pureza:98%Cor e Forma:SolidPeso molecular:273.33O-GlcNAcase-IN-4
CAS:<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Fórmula:C16H22FN5O3SCor e Forma:SolidPeso molecular:383.44OXi8007
CAS:<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Fórmula:C26H24NNa2O10PCor e Forma:SolidPeso molecular:587.428Tubulin inhibitor 7
CAS:<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Fórmula:C21H14N2O4Pureza:98%Cor e Forma:SolidPeso molecular:358.35Tubulin polymerization-IN-7
CAS:<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Fórmula:C28H24N4O6SCor e Forma:SolidPeso molecular:544.58K-80003
CAS:<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Fórmula:C22H21FO2Pureza:99.76%Cor e Forma:SolidPeso molecular:336.4PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Fórmula:C29H36ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:554.08NC043
CAS:<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Fórmula:C20H26O4Pureza:98%Cor e Forma:SolidPeso molecular:330.42PP2A Cancerous-IN-1
CAS:<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Fórmula:C30H24N4O3Cor e Forma:SolidPeso molecular:488.54PU3
CAS:<p>PU3 is an inhibitor of Hsp90.</p>Fórmula:C19H25N5O3Pureza:98%Cor e Forma:SolidPeso molecular:371.43PD-173956
CAS:<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Fórmula:C20H13Cl2FN4OCor e Forma:SolidPeso molecular:415.25Aha1/Hsp90-IN-1
CAS:<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Fórmula:C22H17F3N4O2Cor e Forma:SolidPeso molecular:426.39OSIP-486823
CAS:<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Fórmula:C29H28FNO4Pureza:98.59%Cor e Forma:SolidPeso molecular:473.54KIF18A-IN-4
CAS:<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Fórmula:C22H27N3O3SCor e Forma:SolidPeso molecular:413.53PF-06651481-00
CAS:<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Fórmula:C26H29Cl2N5O3Pureza:97.01%Cor e Forma:SolidPeso molecular:530.45NVS-PAK1-C
CAS:<p>NVS-PAK1-1: potent PAK1 inhibitor, IC50 5 nM (dephosphorylated), 6 nM (phosphorylated); ATP-competitive; weaker on PAK2 (IC50 270 nM, 720 nM).</p>Fórmula:C22H23ClF3N5OCor e Forma:SoildPeso molecular:465.9EC 144
CAS:<p>EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.</p>Fórmula:C21H24ClN5O2Cor e Forma:SolidPeso molecular:413.9PS315
CAS:<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Fórmula:C23H19ClO2Pureza:98%Cor e Forma:SolidPeso molecular:362.85Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Fórmula:C28H29BrN4O3Pureza:98%Cor e Forma:SolidPeso molecular:549.46Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Fórmula:C22H19NO2Cor e Forma:SolidPeso molecular:329.39CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Fórmula:C19H17N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:351.36BCR-ABL-IN-1
CAS:<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Fórmula:C23H21F4N5OPureza:98%Cor e Forma:SolidPeso molecular:459.44GF 15
CAS:<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Fórmula:C23H21ClO6Pureza:98%Cor e Forma:SolidPeso molecular:428.86CHPG
CAS:<p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>Fórmula:C8H8ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:201.61Microtubule inhibitor 6
CAS:<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Fórmula:C24H19FN2O5Cor e Forma:SolidPeso molecular:434.42NSC-668036
CAS:<p>NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.</p>Fórmula:C21H36N2O9Pureza:98%Cor e Forma:SolidPeso molecular:460.52NAMI-A
CAS:<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Fórmula:C8H15Cl4N4ORuSPureza:98%Cor e Forma:SolidPeso molecular:458.18Tau-aggregation-IN-1
CAS:<p>Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).</p>Fórmula:C28H37N5O2SCor e Forma:SolidPeso molecular:507.69Tubulin polymerization-IN-29
CAS:<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Fórmula:C25H20FNO6Cor e Forma:SolidPeso molecular:449.43AK963
CAS:<p>AK963 (40708899) is a powerful PAK1 inhibitor reducing gastric cancer cell growth via the PAK1-NFκB-CyclinB1 pathway.</p>Fórmula:C16H18N2OCor e Forma:SolidPeso molecular:254.33Valategrast hydrochloride
CAS:<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Fórmula:C30H33Cl4N3O4Pureza:98%Cor e Forma:SolidPeso molecular:641.41EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Fórmula:C25H31F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:476.53(R)-TTBK1-IN-1
CAS:<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Fórmula:C18H19N5O2Cor e Forma:SolidPeso molecular:337.38BCR-ABL-IN-6
CAS:<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Fórmula:C27H22F3N5O2Cor e Forma:SolidPeso molecular:505.49SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Fórmula:C15H14ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:319.81Tubulin polymerization-IN-16
CAS:<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Fórmula:C24H27N5O5Cor e Forma:SolidPeso molecular:465.5Syntelin
CAS:<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Fórmula:C21H20N6O2S3Cor e Forma:SolidPeso molecular:484.62LS-104
CAS:<p>LS-104 is a JAK2 inhibitor.</p>Fórmula:C19H16N2O3Cor e Forma:SolidPeso molecular:320.34Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Fórmula:C21H21N5O5Cor e Forma:SolidPeso molecular:423.42Tubulin polymerization-IN-25
CAS:<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Fórmula:C24H18N2O3SCor e Forma:SolidPeso molecular:414.48AKT-IN-8
CAS:<p>AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).</p>Fórmula:C22H25ClN6O3Cor e Forma:SolidPeso molecular:456.93AKT-IN-5
CAS:<p>AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.</p>Fórmula:C23H20N4O2Cor e Forma:SolidPeso molecular:384.43Zalunfiban
CAS:<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Fórmula:C16H18N8O2SCor e Forma:SolidPeso molecular:386.43Zarilamide
CAS:<p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>Fórmula:C11H11ClN2O2Cor e Forma:SolidPeso molecular:238.67Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Fórmula:C27H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:458.55CCT251236
CAS:<p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>Fórmula:C32H32N4O5Pureza:98.82% - 99.89%Cor e Forma:SolidPeso molecular:552.62Tubulin polymerization-IN-36
CAS:<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Fórmula:C18H18N2O3Cor e Forma:SolidPeso molecular:310.35Neuroinflammatory-IN-3
CAS:<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Fórmula:C19H19ClO3Cor e Forma:SolidPeso molecular:330.81Sibrafiban
CAS:<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Fórmula:C20H28N4O6Cor e Forma:SolidPeso molecular:420.46Tubulin polymerization-IN-20
CAS:<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Fórmula:C25H24FNO5Cor e Forma:SolidPeso molecular:437.46Tubulin polymerization-IN-42
CAS:<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Fórmula:C22H21NO5Cor e Forma:SolidPeso molecular:379.41Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Fórmula:C38H44NO9PCor e Forma:SolidPeso molecular:689.73Clathrin-IN-2
CAS:<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Fórmula:C17H18Br2N2OCor e Forma:SolidPeso molecular:426.15HSP90-IN-20
CAS:<p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>Fórmula:C26H32N4O4Cor e Forma:SolidPeso molecular:464.56Tubulin polymerization-IN-27
CAS:<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Fórmula:C22H20N2O2Cor e Forma:SolidPeso molecular:344.41YM-1
CAS:<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Fórmula:C20H20ClN3OS2Cor e Forma:SolidPeso molecular:417.98Tubulin inhibitor 12
CAS:<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Fórmula:C24H20N2OCor e Forma:SolidPeso molecular:352.43BCR-ABL1-IN-1
CAS:<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Fórmula:C18H12F3N3O2Cor e Forma:SolidPeso molecular:359.3Drp1-IN-1
CAS:<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Fórmula:C22H24N8OSCor e Forma:SolidPeso molecular:448.54
