Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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AB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Fórmula:C137H215IN30O45SCor e Forma:SolidPeso molecular:3161.32Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Fórmula:C24H20FN3O3Cor e Forma:SolidPeso molecular:417.43KT D606
CAS:<p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>Fórmula:C59H50N6O10Cor e Forma:SolidPeso molecular:1003.06α-Linolenic Acid (sodium salt)
CAS:<p>α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.</p>Fórmula:C18H29NaO2Cor e Forma:SolidPeso molecular:300.41Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Fórmula:C25H41N11O8SCor e Forma:SolidPeso molecular:655.727αVβ8-IN-1
CAS:<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Fórmula:C25H32ClN5O4Cor e Forma:SolidPeso molecular:502.01DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Cor e Forma:Odour SolidAT-1002
CAS:<p>AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.</p>Fórmula:C32H53N9O7SPureza:98%Cor e Forma:SolidPeso molecular:707.88Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Fórmula:C83H127N25O34SPureza:98%Cor e Forma:SolidPeso molecular:2051.11FRATide
CAS:<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Fórmula:C55H102N2O2Cor e Forma:SolidPeso molecular:823.433INY-03-041
<p>INY-03-041, a PROTAC pan-AKT degrader, targets AKT1/2/3 with IC50s: 2.0/6.8/3.5 nM; GDC-0068 + Lenalidomide fusion.</p>Fórmula:C44H56ClN7O5Pureza:98%Cor e Forma:SolidPeso molecular:798.41FGFRs-IN-1
<p>FGFRs-IN-1 (Compound A16) is an orally active inhibitor targeting FGFR1/2/3/4, with IC50 values of 2.3, 7, 11, and 163 nM respectively. It also inhibits VEGFR1/2/3, Abl, and Flt3, with IC50 values of 61, 176, 112, 26, and 353 nM. The compound shows weak inhibition of CYP enzymes. FGFRs-IN-1 reduces the expression of α-SMA and collagen I, and it inhibits epithelial-mesenchymal transition (EMT) in A549 cells stimulated by TGF-β1. Additionally, FGFRs-IN-1 demonstrates anti-inflammatory activity in mouse models of lung fibrosis induced by Bleomycin and liver fibrosis induced by CCl4.</p>Fórmula:C28H26Cl2N4O3Cor e Forma:SolidPeso molecular:537.44Maydispenoid A
<p>Maydispenoid A is a strong immunosuppressant that hinders murine splenocyte proliferation.</p>Fórmula:C26H40O4Cor e Forma:SolidPeso molecular:416.59Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Fórmula:C12H12O9Cor e Forma:SolidPeso molecular:300.22LKKTETQ
CAS:<p>LKKTETQ, a peptide segment within thymosin β 4, constitutes the protein's active site responsible for actin binding, cell migration, and wound healing.</p>Fórmula:C36H66N10O13Cor e Forma:SolidPeso molecular:846.981Crosstide
CAS:<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Fórmula:C48H77N17O17Pureza:98%Cor e Forma:SolidPeso molecular:1164.23Pironetin
CAS:<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Fórmula:C19H32O4Pureza:98%Cor e Forma:SolidPeso molecular:324.45Aberrant tau degrader 2
CAS:<p>Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.</p>Fórmula:C19H27N7O3SCor e Forma:SolidPeso molecular:433.528TAT-Gap19 TFA
<p>TAT-Gap19 TFA is a peptide that inhibits Cx43 hemichannels but not gap junctions and may reduce liver fibrosis.</p>Fórmula:C121H213F3N46O28Cor e Forma:SolidPeso molecular:2817.27SNIPER(ABL)-024
CAS:<p>SNIPER(ABL)-024, a compound that conjugates GNF5 (ABL inhibitor) to an LCL161 derivative (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels,</p>Fórmula:C52H61F3N8O9SPureza:98%Cor e Forma:SolidPeso molecular:1031.15hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Fórmula:C22H24N4OCor e Forma:SolidPeso molecular:360.45SNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Fórmula:C42H52F3N7O8Pureza:98%Cor e Forma:SolidPeso molecular:839.9ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Fórmula:C47H53BrCl2N10O7SPureza:98%Cor e Forma:SolidPeso molecular:1052.86AKT1-IN-9
<p>AKT1-IN-9 (4) is a selective inhibitor of the AKT1(E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.</p>Fórmula:C33H25FN6O4Cor e Forma:SolidPeso molecular:588.588Sudocetaxel
CAS:<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Fórmula:C48H59NO16Cor e Forma:SolidPeso molecular:905.98DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Cor e Forma:Odour SolidZolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Pureza:95% - 95%Cor e Forma:LiquidPeso molecular:150 kDaLDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Fórmula:C69H81N11O17SPureza:98%Cor e Forma:SolidPeso molecular:1368.53Filanesib TFA
CAS:<p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>Fórmula:C22H23F5N4O4SPureza:98%Cor e Forma:SolidPeso molecular:534.5GSK-3β inhibitor 24
<p>GSK-3β inhibitor24 (Compound 41) is a potent GSK-3β inhibitor with an IC50 of 0.22 nM. It increases GSK-3β phosphorylation at the Ser9 site in a dose-dependent manner and inhibits tau protein hyperphosphorylation by reducing the abundance of p-tau-Ser396. The compound upregulates β-catenin and neurogenesis-related markers (GAP43 and MAP-2), demonstrating significant anti-Alzheimer's disease (AD) activity.</p>Fórmula:C26H18N4O3Cor e Forma:SolidPeso molecular:434.446Abl Cytosolic Substrate
CAS:<p>Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).</p>Fórmula:C64H101N15O16Pureza:98%Cor e Forma:SolidPeso molecular:1336.58Arimoclomol citrate
CAS:<p>Arimoclomol citrate boosts Hsp expression, aiding protein aggregation and neuron protection.</p>Fórmula:C20H28ClN3O10Cor e Forma:SolidPeso molecular:505.91α2β1 Integrin Ligand Peptide TFA
<p>α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is a</p>Fórmula:C16H23F3N4O11Pureza:98%Cor e Forma:SolidPeso molecular:504.37Foxy-5
CAS:<p>Foxy-5 is a wnt5a peptide mimetic</p>Fórmula:C26H42N6O12S2Pureza:98%Cor e Forma:SolidPeso molecular:694.77DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Cor e Forma:Odour SolidSNIPER(ABL)-058
CAS:<p>SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein</p>Fórmula:C62H75N11O9SPureza:98%Cor e Forma:SolidPeso molecular:1150.393-Phenyltoxoflavin
CAS:<p>3-Phenyltoxoflavin (Phenyltoxoflavin) is an inhibitor of HSP90 (Kd = 585 nM) with anti-cancer activity.</p>Fórmula:C13H11N5O2Pureza:99.88%Cor e Forma:SolidPeso molecular:269.26GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Fórmula:C22H37N9O10Pureza:98%Cor e Forma:SolidPeso molecular:587.58PDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Fórmula:C25H17N3O2SPureza:99.93%Cor e Forma:SoildPeso molecular:423.4920-O-Demethyl-AP3
CAS:<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Fórmula:C31H41ClN2O9Cor e Forma:SolidPeso molecular:621.12Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Fórmula:C32H55N9O10Pureza:98%Cor e Forma:SolidPeso molecular:725.83Protein Kinase C (19-36)
CAS:Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.Fórmula:C93H159N35O24Pureza:98%Cor e Forma:SolidPeso molecular:2151.48Sangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Fórmula:C12H15N5O5Pureza:99.85%Cor e Forma:SolidPeso molecular:309.28hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Cor e Forma:Odour SolidAnticancer agent 139
<p>Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high</p>Fórmula:C16H12F3N3OCor e Forma:SolidPeso molecular:319.286BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Fórmula:C45H47Br2N2O3PCor e Forma:SolidPeso molecular:854.65Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Fórmula:C21H29N5O6Pureza:99.57%Cor e Forma:SolidPeso molecular:447.48SNIPER(ABL)-015
<p>SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5</p>Fórmula:C58H70F3N9O9Pureza:98%Cor e Forma:SolidPeso molecular:1094.23Osemitamab (FUT8-KO)
<p>Osemitamab (FUT8-KO) is a monoclonal antibody targeting claudin-18.2, expressed in CHO cells with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of fucose heightens the antibody's ADCC effect. When combined with Capecitabine and Oxaliplatin, it can be used for G/GEJ cancer research.</p>Cor e Forma:Odour LiquidSIAIS100
<p>SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.</p>Fórmula:C44H50ClF2N9O5SCor e Forma:SolidPeso molecular:890.44Peptide5
CAS:<p>Connexin43 peptide: lessens swelling, astrogliosis, inflammation, neuron death post-spinal injury; analgesic for neuropathic pain.</p>Fórmula:C60H98N16O20SCor e Forma:SolidPeso molecular:1395.6Akt1-IN-1
<p>Akt1-IN-1: Potent, selective Akt1 inhibitor, IC50 18.79 nM, non-teratogenic/hepatotoxic/cardiotoxic, useful in cancer research.</p>Fórmula:C31H34FN5O5S2Cor e Forma:SolidPeso molecular:639.76HSDVHK-NH2
CAS:<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Fórmula:C30H48N12O9Pureza:98%Cor e Forma:SolidPeso molecular:720.78HA15-Biotin
CAS:<p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>Fórmula:C37H45N7O5S3Cor e Forma:SolidPeso molecular:763.99Fuzapladib
CAS:<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Fórmula:C15H20F3N3O3SPureza:99.87%Cor e Forma:SoildPeso molecular:379.4MS170
CAS:<p>MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.</p>Fórmula:C45H56ClN9O7Cor e Forma:SolidPeso molecular:870.45Anti-CDH17/Cadherin-17 Antibody (10C12)
<p>Anti-CDH17/Cadherin-17 Antibody (10C12) is a human-derived antibody produced in CHO cells, targeting CDH17. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour LiquidSMS 121
CAS:<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Fórmula:C20H21NO5Pureza:98.29%Cor e Forma:SoildPeso molecular:355.38Orbofiban acetate
CAS:<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Fórmula:C19H27N5O6Cor e Forma:SolidPeso molecular:421.45Certepetide
CAS:<p>Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.</p>Fórmula:C37H60N14O14S2Cor e Forma:SolidPeso molecular:989.09Vinzolidine
CAS:<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Fórmula:C48H58ClN5O9Cor e Forma:SolidPeso molecular:884.46PM050489
CAS:<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Fórmula:C31H44ClN3O7Cor e Forma:SolidPeso molecular:606.15Gamitrinib TPP hexafluorophosphate
CAS:<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Fórmula:C52H65F6N3O8P2Pureza:98.52% - 98.52%Cor e Forma:SolidPeso molecular:1036.03K34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Fórmula:C26H30ClN3O4Pureza:99.76% - 99.89%Cor e Forma:SoildPeso molecular:483.99Wortmannin-Rapamycin Conjugate
CAS:<p>Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer.</p>Fórmula:C88H131N3O23Cor e Forma:SolidPeso molecular:1599.014Solidagonic acid
CAS:<p>Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.</p>Fórmula:C22H34O4Cor e Forma:SolidPeso molecular:362.5SRI 37892
CAS:<p>SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.</p>Fórmula:C26H19N5O2SPureza:99.93%Cor e Forma:SolidPeso molecular:465.53MPH-220
CAS:<p>MPH-220: Oral myosin-2 inhibitor, induces muscle relaxation, useful for spasticity research.</p>Fórmula:C20H21N3O3SCor e Forma:SolidPeso molecular:383.46LXY3
CAS:<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Fórmula:C32H43N11O15S2Cor e Forma:SolidPeso molecular:885.88Tubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Fórmula:C19H15Cl2N3O3SCor e Forma:SolidPeso molecular:436.31Akt/SKG Substrate Peptide
CAS:<p>substrate for Akt/PKB</p>Fórmula:C36H59N13O9Pureza:98%Cor e Forma:SolidPeso molecular:817.94Phomopsin A
CAS:<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Fórmula:C36H45ClN6O12Pureza:98%Cor e Forma:SolidPeso molecular:789.23BCR-ABL-IN-3
CAS:<p>BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.</p>Fórmula:C20H17ClF2N4O3SCor e Forma:SolidPeso molecular:466.89Chaetominine
CAS:<p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>Fórmula:C22H18N4O4Cor e Forma:SolidPeso molecular:402.40YS-49 monohydrate
<p>YS-49, a PI3K/Akt activator, curbs RhoA/PTEN; inhibits VSMC growth by inducing HO-1; an isoquinoline alkaloid that stimulates cardiac β-adrenoceptors.</p>Fórmula:C20H22BrNO3Cor e Forma:SolidPeso molecular:404.3Lys-Gln-Ala-Gly-Asp-Val
CAS:<p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>Fórmula:C25H44N8O10Cor e Forma:SolidPeso molecular:616.66Dynamin inhibitory peptide TFA
<p>Dynamin inhibitory peptide TFA hinders dynamin-amphiphysin interaction and endocytosis, affecting dopamine D3 and GABA A receptors.</p>Fórmula:C49H81F3N18O16Cor e Forma:SolidPeso molecular:1235.27Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Pureza:98%Cor e Forma:Odour SolidSQLE-IN-1
CAS:<p>SQLE-IN-1 is a SQLE inhibitor with antitumor activity that inhibits the proliferation of Huh7 and the protein expression of PI3K and AKT.</p>Fórmula:C24H21F2N5O2SPureza:99.89%Cor e Forma:SoildPeso molecular:481.52Zolbetuximab
CAS:<p>Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.</p>Pureza:95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Cor e Forma:LiquidPeso molecular:147.09 kDaFibronectin CS1 Peptide
CAS:<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Fórmula:C38H64N8O15Pureza:98%Cor e Forma:SolidPeso molecular:872.96RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Fórmula:C11H15ClF3N3OCor e Forma:SolidPeso molecular:297.77-Epi-10-oxo-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Fórmula:C43H51NO14Pureza:98%Cor e Forma:SolidPeso molecular:805.86Eudebeiolide B
CAS:<p>Eudebeiolide B, isolated from Salvia plebeia R.</p>Fórmula:C15H18O4Pureza:98%Cor e Forma:SolidPeso molecular:262.3DynaMin inhibitory peptide, myristoylated
CAS:<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Fórmula:C61H107N19O14Pureza:98%Cor e Forma:SolidPeso molecular:1330.64Dihydrocephalomannine
CAS:<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Fórmula:C45H55NO14Pureza:98%Cor e Forma:SolidPeso molecular:833.928Cepeginterferon alfa-2b
CAS:<p>Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.</p>Cor e Forma:LiquidMyelin Basic Protein
CAS:<p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>Fórmula:C60H103N21O17Pureza:98%Cor e Forma:SolidPeso molecular:1390.59Jatrophone
CAS:<p>Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.</p>Fórmula:C20H24O3Cor e Forma:SolidPeso molecular:312.4MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Fórmula:C54H66N4O10Cor e Forma:SolidPeso molecular:931.12Bisindolylmaleimide III
CAS:<p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>Fórmula:C23H20N4O2Pureza:98.6%Cor e Forma:SolidPeso molecular:384.43Tubulin inhibitor 24
CAS:<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Fórmula:C22H21N3O3Pureza:99.99%Cor e Forma:SolidPeso molecular:375.42DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Cor e Forma:Odour Solidβ-catenin-IN-7
<p>β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, and</p>Fórmula:C17H13BrN2O2SCor e Forma:SolidPeso molecular:389.27FAK-IN-7
CAS:<p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>Fórmula:C16H13N3OSPureza:98.18%Cor e Forma:SolidPeso molecular:295.36SNIPER(ABL)-039
CAS:<p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>Fórmula:C54H68ClN11O9S2Pureza:98%Cor e Forma:SolidPeso molecular:1114.77Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Fórmula:C28H25N3O4SCor e Forma:SolidPeso molecular:499.58Pep2m, myristoylated
CAS:<p>Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.</p>Fórmula:C63H118N18O14SPureza:98%Cor e Forma:SolidPeso molecular:1383.8PKC β pseudosubstrate
CAS:<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Fórmula:C177H294N62O38S3Pureza:98%Cor e Forma:SolidPeso molecular:3994.84TNIK-IN-7
CAS:<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Fórmula:C23H22N4O2Pureza:99.87%Cor e Forma:SoildPeso molecular:386.45
