Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1472 produtos de "Sinalização Citoesquelética"
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Ifinatamab
CAS:Ifinatamab is a humanised monoclonal immunoglobulin,B7-H3 protein.ADC drug Ifinatamab deruxtecan,small cell lung cancer (SCLC).Pureza:95%Cor e Forma:LiquidOS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Pureza:95%Cor e Forma:Odour LiquidPasotuxizumab
CAS:<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Cor e Forma:LiquidPlamotamab
CAS:<p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>Cor e Forma:Liquid17-AEP-GA
CAS:<p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>Fórmula:C34H50N4O8Pureza:97.77% - 99.56%Cor e Forma:SolidPeso molecular:642.78Tubulin polymerization-IN-2
CAS:<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Fórmula:C17H12F2N2O2Cor e Forma:SolidPeso molecular:314.29Meclofenamic acid
CAS:Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.Fórmula:C14H11Cl2NO2Pureza:99.98%Cor e Forma:SolidPeso molecular:296.15SB273005
CAS:SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.Fórmula:C22H24F3N3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:451.44N-Desmethylnefopam
CAS:N-Desmethylnefopam is the main Nefopam metabolite .Fórmula:C16H17NOPureza:98%Cor e Forma:SolidPeso molecular:239.31Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Cor e Forma:SolidPeso molecular:561.5IPA-3
CAS:IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).Fórmula:C20H14O2S2Pureza:97.40%Cor e Forma:SolidPeso molecular:350.45Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Fórmula:C28H33N5O4SPureza:98.33%Cor e Forma:SolidPeso molecular:535.66Phorbol 12,13-dibutyrate
CAS:Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.Fórmula:C28H40O8Pureza:99.32% - 99.37%Cor e Forma:SolidPeso molecular:504.61D-GsMTx4 TFA
<p>D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia/reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.</p>Fórmula:C187H279F3N48O48S6Pureza:99.29% - 99.65%Cor e Forma:SoildPeso molecular:4216.93Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Fórmula:C22H36N2O5SPureza:99.83%Cor e Forma:SolidPeso molecular:440.6Auristatin F
CAS:Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.Fórmula:C40H67N5O8Pureza:98.41% - 99.25%Cor e Forma:SolidPeso molecular:745.99Tubulin inhibitor 28
CAS:Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.Fórmula:C12H8Br2S2Cor e Forma:SolidPeso molecular:376.13Alyssin, (S)-
CAS:Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells.Fórmula:C7H13NOS2Cor e Forma:SolidPeso molecular:191.31ARUK3001185
CAS:<p>ARUK3001185 (8l): potent, selective Notum inhibitor; oral, brain-penetrant; IC50=6.7 nM; for rodent disease models.</p>Fórmula:C9H4Cl2F3N3Cor e Forma:SolidPeso molecular:282.05
