Sinalização Citoesquelética

Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.

Foram encontrados 1381 produtos de "Sinalização Citoesquelética"

Pureza (%)

100

produtos por página.

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Cardionogen 1
CAS:
- 577696-37-8
Wnt signaling modulator
Fórmula:C₁₃H₁₄N₄OS
Pureza:98%
Cor e Forma:Solid
Peso molecular:274.34
Ref: TM-T22625
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CH5164840
CAS:
- 1052645-73-4
CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.
Fórmula:C₁₉H₂₃N₅O₂S
Cor e Forma:Solid
Peso molecular:385.48
Ref: TM-T71526
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THK-5117
CAS:
- 1374107-54-6
THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.
Fórmula:C₁₉H₁₉FN₂O₂
Cor e Forma:Solid
Peso molecular:326.36
Ref: TM-T60907
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AJH-836
CAS:
- 388621-67-8
AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of
Fórmula:C₂₂H₃₈O₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:382.53
Ref: TM-T78833
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Alyssin
CAS:
- 646-23-1
Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.
Fórmula:C₇H₁₃NOS₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:191.31
Ref: TM-T26605
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OSIP-486823
CAS:
- 200803-37-8
OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.
Fórmula:C₂₉H₂₈FNO₄
Pureza:98.59%
Cor e Forma:Solid
Peso molecular:473.54
Ref: TM-T13807
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HSP90-IN-22
CAS:
- 442898-75-1
HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in
Fórmula:C₂₅H₃₀N₄O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:434.53
Ref: TM-T79083
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Aha1/Hsp90-IN-1
CAS:
- 2768265-58-1
Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.
Fórmula:C₂₂H₁₇F₃N₄O₂
Cor e Forma:Solid
Peso molecular:426.39
Ref: TM-T62307
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PF-2771
CAS:
- 2070009-55-9
PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.
Fórmula:C₂₉H₃₆ClN₅O₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:554.08
Ref: TM-T12434
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YM-1
CAS:
- 409086-68-6
YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.
Fórmula:C₂₀H₂₀ClN₃OS₂
Cor e Forma:Solid
Peso molecular:417.98
Ref: TM-T73579
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Tubulin polymerization-IN-18
CAS:
- 1258011-23-2
Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.
Fórmula:C₂₅H₂₅NO₆
Cor e Forma:Solid
Peso molecular:435.47
Ref: TM-T62477
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Valategrast
CAS:
- 220847-86-9
Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.
Fórmula:C₃₀H₃₂Cl₃N₃O₄
Pureza:98%
Cor e Forma:Solid
Peso molecular:604.95
Ref: TM-T13277
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Dihydrocytochalasin B
CAS:
- 39156-67-7
Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.
Fórmula:C₂₉H₃₉NO₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:481.62
Ref: TM-T11042
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BCR-ABL-IN-1
CAS:
- 188260-50-6
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.
Fórmula:C₂₃H₂₁F₄N₅O
Pureza:98%
Cor e Forma:Solid
Peso molecular:459.44
Ref: TM-T10488
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PF-06651481-00
CAS:
- 1391063-17-4
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
Fórmula:C₂₆H₂₉Cl₂N₅O₃
Pureza:97.01%
Cor e Forma:Solid
Peso molecular:530.45
Ref: TM-T28374
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Tubulin inhibitor 18
CAS:
- 2762382-51-2
"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."
Fórmula:C₂₂H₂₆O₅
Cor e Forma:Solid
Peso molecular:370.44
Ref: TM-T61472
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β-glycosidase-IN-1
CAS:
- 176485-27-1
β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.
Fórmula:C₁₃H₂₃NO₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:273.33
Ref: TM-T13478
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GR 144053 trihydrochloride
CAS:
- 1215333-48-4
platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist
Fórmula:C₁₈H₃₀Cl₃N₅O₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:454.82
Ref: TM-T22807
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Cevipabulin
CAS:
- 849550-05-6
Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell
Fórmula:C₁₈H₁₈ClF₅N₆O
Pureza:99.53%
Cor e Forma:Solid
Peso molecular:464.82
Ref: TM-T10772
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Sibrafiban
CAS:
- 172927-65-0
Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.
Fórmula:C₂₀H₂₈N₄O₆
Cor e Forma:Solid
Peso molecular:420.46
Ref: TM-T28775