Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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Bisindolylmaleimide VIII acetate
CAS:<p>Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.</p>Fórmula:C26H26N4O4Pureza:99.27%Cor e Forma:SolidPeso molecular:458.51CMPD101
CAS:<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Fórmula:C24H21F3N6OPureza:99.01% - 99.04%Cor e Forma:SolidPeso molecular:466.46BNC105
CAS:<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Fórmula:C20H20O7Pureza:96.57%Cor e Forma:SolidPeso molecular:372.37Imatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:589.71N-Desmethyltamoxifen hydrochloride
CAS:<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Fórmula:C25H28ClNOPureza:99.15%Cor e Forma:SolidPeso molecular:393.95Xentuzumab
CAS:<p>Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.</p>Pureza:95% - > 95%Cor e Forma:LiquidPeso molecular:143.7 kDaCol003
CAS:<p>Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).</p>Fórmula:C14H11NO4Pureza:98.67% - 99.03%Cor e Forma:SolidPeso molecular:257.24ATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Cor e Forma:SolidPeso molecular:711.67Elarofiban TFA
CAS:<p>Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.</p>Fórmula:C26H34F6N4O8Pureza:99.08%Cor e Forma:SoildPeso molecular:644.56Efalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Cor e Forma:LiquidPeso molecular:146.14 kDaA-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Cor e Forma:SolidPeso molecular:321.22PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Pureza:95.42%Cor e Forma:SoildZagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Pureza:95% - > 95%Cor e Forma:LiquidPeso molecular:145.3 kDaBOS-172722
CAS:<p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>Fórmula:C24H30N8OPureza:99.37%Cor e Forma:SolidPeso molecular:446.55Tirbanibulin Mesylate
CAS:<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Fórmula:C27H33N3O6SPureza:99%Cor e Forma:SolidPeso molecular:527.63NVS-PAK1-1
CAS:<p>NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).</p>Fórmula:C23H25ClF3N5OPureza:99.35%Cor e Forma:SolidPeso molecular:479.93GRP78-IN-3
CAS:<p>GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.</p>Fórmula:C17H18N4O2SPureza:99.11%Cor e Forma:SoildPeso molecular:342.42Akt3 degrader 1
CAS:<p>Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.</p>Fórmula:C53H72N8O4Pureza:98.12% - 99.02%Cor e Forma:SolidPeso molecular:885.19ALK inhibitor 2
CAS:<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Fórmula:C23H28ClN7O3SPureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:518.03AC 7739
CAS:<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Fórmula:C18H22ClNO4Pureza:99.38% - 99.55%Cor e Forma:SoildPeso molecular:351.83Bersanlimab
CAS:<p>Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:144.22 kDaAbciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:95.18 kDaLarazotide acetate
CAS:<p>Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.</p>Fórmula:C34H59N9O12Pureza:95.53% - 99.425%Cor e Forma:SolidPeso molecular:785.89RWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Fórmula:C18H17F3N4O2SPureza:99.09%Cor e Forma:SolidPeso molecular:410.41Bosutinib
CAS:<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Talquetamab
CAS:<p>Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.</p>Cor e Forma:LiquidPeso molecular:144.59 kDaOrbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Fórmula:C19H24F3N5O6Pureza:97.21% - 98.72%Cor e Forma:SolidPeso molecular:475.42Spiperone
CAS:<p>Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.</p>Fórmula:C23H26FN3O2Pureza:99.34% - 99.91%Cor e Forma:SolidPeso molecular:395.47Arimoclomol maleate
CAS:<p>Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.</p>Fórmula:C18H24ClN3O7Pureza:99.44% - 99.98%Cor e Forma:SolidPeso molecular:429.85Danicamtiv
CAS:<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Fórmula:C16H20F3N5O4SPureza:99.38%Cor e Forma:SolidPeso molecular:435.42Otelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Pureza:>95%Cor e Forma:LiquidDonanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Pureza:95%Cor e Forma:LiquidGNE 2861
CAS:<p>GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.</p>Fórmula:C22H26N6O2Pureza:97.03%Cor e Forma:SolidPeso molecular:406.48Verubulin hydrochloride
CAS:<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Fórmula:C17H18ClN3OPureza:98.29% - 99.77%Cor e Forma:SolidPeso molecular:315.8Rifabutin
CAS:<p>Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.</p>Fórmula:C46H62N4O11Pureza:98.87% - 99.7%Cor e Forma:Red-Violet Crystalline PowderPeso molecular:847Mitoxantrone dihydrochloride
CAS:<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Cor e Forma:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Nilotinib
CAS:<p>Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.</p>Fórmula:C28H22F3N7OPureza:99.89% - >99.99%Cor e Forma:Off-White SolidPeso molecular:529.52IPI-493
CAS:<p>IPI-493 is a bioactive chemical.</p>Fórmula:C28H39N3O8Pureza:>99.99%Cor e Forma:SolidPeso molecular:545.62Mosunetuzumab
CAS:<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Pureza:SDS-PAGE:94.4%;SEC-HPLC:96.1%Cor e Forma:LiquidPeso molecular:146.27 kDaAdropin (34-76) (human, mouse, rat)
CAS:<p>Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.</p>Fórmula:C190H293N55O68S2Pureza:94.23% - 99.95%Cor e Forma:SolidPeso molecular:4499.82Tilavonemab
CAS:<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Pureza:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Cor e Forma:LiquidCibisatamab
CAS:<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Cor e Forma:LiquidPeso molecular:191.1 kDaEthoxyquin
CAS:<p>Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.</p>Fórmula:C14H19NOPureza:97.15% - 98.73%Cor e Forma:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Peso molecular:217.31IMAB027
CAS:<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Pureza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Cor e Forma:LiquidCC-99677
CAS:<p>CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.</p>Fórmula:C22H20ClN5O3SPureza:99.59%Cor e Forma:SolidPeso molecular:469.94Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01SGC-AAK1-1
CAS:<p>SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.</p>Fórmula:C21H25N5O3SPureza:99.68%Cor e Forma:SolidPeso molecular:427.52Paprotrain
CAS:<p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>Fórmula:C16H11N3Pureza:99.91%Cor e Forma:SolidPeso molecular:245.28Tidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Pureza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Cor e Forma:LiquidVeltuzumab
CAS:<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Cor e Forma:LiquidGlofitamab
CAS:<p>Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.</p>Pureza:SDS-PAGE:98.2%;SEC-HPLC:98.0%Cor e Forma:LiquidPeso molecular:170.37 kDaDelcasertib
CAS:<p>Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).</p>Fórmula:C120H199N45O34S2Pureza:99.96%Cor e Forma:SolidPeso molecular:2880.28Fluorofenidone
CAS:<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Fórmula:C12H10FNOPureza:99.85%Cor e Forma:SolidPeso molecular:203.21Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Pureza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Cor e Forma:Liquid(+)-Blebbistatin
CAS:<p>(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.</p>Fórmula:C18H16N2O2Pureza:99.88%Cor e Forma:SolidPeso molecular:292.33Meclofenamic acid sodium
CAS:<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Fórmula:C14H10Cl2NNaO2Pureza:98% - 98.96%Cor e Forma:SolidPeso molecular:318.14ADH-1 trifluoroacetate
CAS:<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Fórmula:C24H35F3N8O8S2Pureza:90.08% - 99.17%Cor e Forma:SolidPeso molecular:684.71Pamidronate Disodium
CAS:<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Fórmula:C3H9NNa2O7P2Pureza:99.86% - 99.93%Cor e Forma:White CrystalsPeso molecular:279.03Recilisib
CAS:<p>Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.</p>Fórmula:C16H13ClO4SPureza:98.85% - 98.96%Cor e Forma:SolidPeso molecular:336.792,3-Butanedione 2-Monoxime
CAS:<p>2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.</p>Fórmula:C4H7NO2Pureza:98.62%Cor e Forma:Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:101.1Abituzumab
CAS:<p>Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.</p>Pureza:>95%Cor e Forma:LiquidTINK-IN-1
CAS:<p>TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.</p>Fórmula:C24H24N4O3Pureza:99.4%Cor e Forma:SoildPeso molecular:416.47Foralumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Cor e Forma:LiquidDasatinib monohydrate
CAS:<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:506.03Tubulin inhibitor 6
CAS:<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Fórmula:C20H14ClNO2SPureza:99.05%Cor e Forma:SolidPeso molecular:367.85Vantictumab
CAS:<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Pureza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Cor e Forma:LiquidDarifenacin hydrobromide
CAS:<p>Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.</p>Fórmula:C28H31BrN2O2Pureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:505.45CK-666
CAS:<p>CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.</p>Fórmula:C18H17FN2OPureza:99.93%Cor e Forma:SolidPeso molecular:296.347-Aminocephalosporanic acid
CAS:<p>7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.</p>Fórmula:C10H12N2O5SPureza:91.05%Cor e Forma:White Solid PowderPeso molecular:272.28DM4
CAS:<p>DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.</p>Fórmula:C38H54ClN3O10SPureza:98.15%Cor e Forma:SolidPeso molecular:780.37Arg-Gly-Asp-Ser acetate
<p>Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.</p>Fórmula:C17H31N7O10Pureza:98.14%Cor e Forma:SolidPeso molecular:493.47LXH254
CAS:<p>LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.</p>Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Cor e Forma:SolidPeso molecular:502.49ALK inhibitor 1
CAS:<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Fórmula:C23H28BrN7O3SPureza:98.27%Cor e Forma:SolidPeso molecular:562.48N-Desmethyl imatinib
CAS:<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Fórmula:C28H29N7OPureza:98.60%Cor e Forma:Off-White To Pale-Yellow SolidPeso molecular:479.58Lyn-IN-1
CAS:<p>Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and Lyn</p>Fórmula:C30H31F3N8OPureza:97% - 98.02%Cor e Forma:SolidPeso molecular:576.62Entasobulin
CAS:<p>Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.</p>Fórmula:C26H18ClN3O2Pureza:98.40%Cor e Forma:SolidPeso molecular:439.89Vedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Pureza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Cor e Forma:LiquidPeso molecular:146.80 kDaAKE-72
CAS:<p>AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.</p>Fórmula:C30H29F3N6OPureza:98.3%Cor e Forma:SoildPeso molecular:546.59Mps1-IN-3
CAS:<p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>Fórmula:C26H31N7O4SPureza:99.25%Cor e Forma:SolidPeso molecular:537.63Bepranemab
CAS:<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Pureza:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Cor e Forma:LiquidAS1949490
CAS:<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Fórmula:C20H18ClNO2SPureza:99.94%Cor e Forma:SolidPeso molecular:371.88Fluocinolone (Acetonide)
CAS:<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Fórmula:C24H30F2O6Pureza:99.29% - 99.82%Cor e Forma:Crystals From Acetone & Hexane SolidPeso molecular:452.49ATN-161 acetate
CAS:<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Fórmula:C25H39N9O10SPureza:98.27%Cor e Forma:SoildPeso molecular:657.7Abrilumab
CAS:<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Cor e Forma:LiquidTeplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Cor e Forma:LiquidPeso molecular:145.79 kDaDSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Cor e Forma:Odour SolidEudebeiolide B
CAS:<p>Eudebeiolide B, isolated from Salvia plebeia R.</p>Fórmula:C15H18O4Pureza:98%Cor e Forma:SolidPeso molecular:262.3Phomopsin A
CAS:<p>Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.</p>Fórmula:C36H45ClN6O12Pureza:98%Cor e Forma:SolidPeso molecular:789.23MS21
CAS:<p>MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.</p>Fórmula:C58H79ClN12O6SCor e Forma:SolidPeso molecular:1107.8611H-Benzo[a]carbazole
CAS:<p>11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.</p>Fórmula:C16H11NPureza:99.14%Cor e Forma:SolidPeso molecular:217.27MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Fórmula:C54H66N4O10Cor e Forma:SolidPeso molecular:931.12DSPE-PEG5000-cRGD
<p>DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.</p>Cor e Forma:Odour SolidTubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Fórmula:C17H13ClN6OSCor e Forma:SolidPeso molecular:384.84HSDVHK-NH2
CAS:<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Fórmula:C30H48N12O9Pureza:98%Cor e Forma:SolidPeso molecular:720.78BCR-ABL-IN-3
CAS:<p>BCR-ABL-IN-3 irreversibly inhibits Bcr-Abl with <100 nM IC50, showing significant anti-cancer effects.</p>Fórmula:C20H17ClF2N4O3SCor e Forma:SolidPeso molecular:466.89Combretastatin A-1 phosphate tetrasodium
CAS:<p>OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.</p>Fórmula:C18H18Na4O12P2Cor e Forma:SolidPeso molecular:580.2420-O-Demethyl-AP3
CAS:<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Fórmula:C31H41ClN2O9Cor e Forma:SolidPeso molecular:621.12Gly-Arg-Gly-Asp-Ser
CAS:<p>Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.</p>Fórmula:C17H30N8O9Pureza:98%Cor e Forma:SolidPeso molecular:490.47Akt/SKG Substrate Peptide
CAS:<p>substrate for Akt/PKB</p>Fórmula:C36H59N13O9Pureza:98%Cor e Forma:SolidPeso molecular:817.94Chaetominine
CAS:<p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>Fórmula:C22H18N4O4Cor e Forma:SolidPeso molecular:402.40LDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Fórmula:C69H81N11O17SPureza:98%Cor e Forma:SolidPeso molecular:1368.53gp96-II
<p>Gp96-II is a gp96-blocking peptide that antagonizes cytokine production induced by gp96-mediated LPS. This compound is useful for research into inflammatory diseases.</p>Fórmula:C200H353N59O53SCor e Forma:SolidPeso molecular:4464.37ML 2-23
<p>ML 2-23 is a potent BCR-ABL degrader operating as a PROTAC, exhibiting selective proteasome-dependent degradation of BCR-ABL within leukemia cells [1].</p>Fórmula:C47H53BrCl2N10O7SPureza:98%Cor e Forma:SolidPeso molecular:1052.86INY-03-041
<p>INY-03-041, a PROTAC pan-AKT degrader, targets AKT1/2/3 with IC50s: 2.0/6.8/3.5 nM; GDC-0068 + Lenalidomide fusion.</p>Fórmula:C44H56ClN7O5Pureza:98%Cor e Forma:SolidPeso molecular:798.41LY 379196
<p>LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.</p>Fórmula:C30H34N4O5SCor e Forma:SolidPeso molecular:562.68TNIK-IN-7
CAS:<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Fórmula:C23H22N4O2Pureza:99.87%Cor e Forma:SoildPeso molecular:386.45αVβ8-IN-1
CAS:<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Fórmula:C25H32ClN5O4Cor e Forma:SolidPeso molecular:502.01Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Fórmula:C12H12O9Cor e Forma:SolidPeso molecular:300.224,4'-Di-O-methylellagic acid
CAS:<p>4,4'-Di-O-methylellagic acid is a useful organic compound for research related to life sciences. The catalog number is T125016 and the CAS number is 3374-77-4.</p>Fórmula:C16H10O8Cor e Forma:SolidPeso molecular:330.248β-catenin-IN-37
CAS:<p>β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI.</p>Fórmula:C13H9N9OCor e Forma:SolidPeso molecular:307.277SNIPER(ABL)-039
CAS:<p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>Fórmula:C54H68ClN11O9S2Pureza:98%Cor e Forma:SolidPeso molecular:1114.77RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Fórmula:C11H15ClF3N3OCor e Forma:SolidPeso molecular:297.7Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Pureza:95% - 95%Cor e Forma:LiquidPeso molecular:150 kDaProtein Kinase C (19-36)
CAS:<p>Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM.</p>Fórmula:C93H159N35O24Pureza:98%Cor e Forma:SolidPeso molecular:2151.48HA15-Biotin
CAS:<p>HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.</p>Fórmula:C37H45N7O5S3Cor e Forma:SolidPeso molecular:763.99KT D606
CAS:<p>KT D606 is a PAK kinase family inhibitor with an IC50 of 4 μM. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.</p>Fórmula:C59H50N6O10Cor e Forma:SolidPeso molecular:1003.06Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg
CAS:<p>Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.</p>Fórmula:C56H110N22O14Pureza:98%Cor e Forma:SolidPeso molecular:1315.61SNIPER(ABL)-058
CAS:<p>SNIPER(ABL)-058, a compound that links Imatinib (ABL inhibitor) with a derivative of LCL161 (IAP ligand) through a linker, effectively decreases BCR-ABL protein</p>Fórmula:C62H75N11O9SPureza:98%Cor e Forma:SolidPeso molecular:1150.39PDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Fórmula:C25H17N3O2SPureza:99.93%Cor e Forma:SoildPeso molecular:423.49DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Cor e Forma:Odour SolidDSPE-PEG1000-iRGD
<p>DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.</p>Cor e Forma:Odour SolidSangivamycin
CAS:<p>Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.</p>Fórmula:C12H15N5O5Pureza:99.85%Cor e Forma:SolidPeso molecular:309.28Ceratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Fórmula:C17H16Br2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:468.14MS170
CAS:<p>MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.</p>Fórmula:C45H56ClN9O7Cor e Forma:SolidPeso molecular:870.452-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Fórmula:C12H24ClNO4Cor e Forma:SolidPeso molecular:281.78Gantofiban
CAS:<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Fórmula:C21H29N5O6Pureza:99.57%Cor e Forma:SolidPeso molecular:447.48Gamitrinib TPP
CAS:<p>Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.</p>Fórmula:C52H65N3O8PPureza:98%Cor e Forma:SolidPeso molecular:891.078Rotigaptide
CAS:<p>Rotigaptide, modulates Cx43 for gap junctions, counteracts uncoupling, and maintains communication under stress.</p>Fórmula:C28H39N7O9Pureza:98%Cor e Forma:SolidPeso molecular:617.65SNIPER(ABL)-050
<p>SNIPER(ABL)-050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker.</p>Fórmula:C68H84N12O9Pureza:98%Cor e Forma:SolidPeso molecular:1213.47DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Cor e Forma:Odour SolidKanosamine hydrochloride
CAS:<p>Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species.</p>Fórmula:C6H14ClNO5Pureza:98%Cor e Forma:SolidPeso molecular:215.63Gamitrinib TPP hexafluorophosphate
CAS:<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Fórmula:C52H65F6N3O8P2Pureza:98.52% - 98.52%Cor e Forma:SolidPeso molecular:1036.03Fibronectin CS1 Peptide
CAS:<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Fórmula:C38H64N8O15Pureza:98%Cor e Forma:SolidPeso molecular:872.96SNIPER(ABL)-020
<p>SNIPER(ABL)-020, a Dasatinib-Bestatin conjugate via linker, inhibits ABL and targets IAP, reducing BCR-ABL protein.</p>Fórmula:C44H59ClN10O8SPureza:98%Cor e Forma:SolidPeso molecular:923.52FRATide
CAS:<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Fórmula:C55H102N2O2Cor e Forma:SolidPeso molecular:823.433SQLE-IN-1
CAS:<p>SQLE-IN-1 is a SQLE inhibitor with antitumor activity that inhibits the proliferation of Huh7 and the protein expression of PI3K and AKT.</p>Fórmula:C24H21F2N5O2SPureza:99.89%Cor e Forma:SoildPeso molecular:481.52para-amino-Blebbistatin
CAS:<p>para-amino-Blebbistatin is a water-soluble, stable, non-phototoxic inhibitor of non-muscle myosin II, with enhanced properties over blebbistatin.</p>Fórmula:C18H17N3O2Cor e Forma:SolidPeso molecular:307.353187-1, N-WASP inhibitor
CAS:<p>Inhibits N-WASP by stabilizing its autoinhibited form, blocking PIP2-induced actin assembly (IC50 ~2 μM), not directly affecting actin polymerization.</p>Fórmula:C96H122N18O16Pureza:98%Cor e Forma:SolidPeso molecular:1784.13Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Fórmula:C28H25N3O4SCor e Forma:SolidPeso molecular:499.58Hypoglycemic agent 3
<p>Compound H26, a derivative of corosolic acid, functions as Hypoglycemic agent 3. It exhibits lipid-lowering and significant blood glucose-reducing properties, making it a potential hypoglycemic drug. Hypoglycemic agent 3 targets MCCC1 to mitigate insulin resistance, and may be useful in researching type 2 diabetes.</p>Fórmula:C32H51NO5Cor e Forma:SolidPeso molecular:529.751Box5 TFA
<p>Box5 TFA, a potent Wnt5a antagonist, impedes Wnt5a signaling, restricts Wnt5a-initiated Ca2+ release, and hampers cell migration, showing promise for melanoma</p>Fórmula:C32H51F3N6O15S2Cor e Forma:SolidPeso molecular:880.9KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Fórmula:C24H21NO5Cor e Forma:SolidPeso molecular:403.43MK2-IN-5
CAS:<p>MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway and</p>Fórmula:C61H113N21O16Pureza:98%Cor e Forma:SolidPeso molecular:1396.68AKTide-2T
CAS:<p>Peptide substrate for Akt/PKB</p>Fórmula:C74H114N28O20Pureza:98%Cor e Forma:SolidPeso molecular:1715.87st-Ht31
CAS:<p>Ht-31 stearate: Blocks RII subunits of PKA & AKAP interaction in cells; cell-permeable.</p>Fórmula:C129H217N29O39Pureza:98%Cor e Forma:SolidPeso molecular:2798.27PROTAC HSP90 degrader BP3
CAS:<p>PROTAC BP3 selectively degrades HSP90, inhibits breast cancer growth (DC50=0.99µM), CRBN-dependent.</p>Fórmula:C32H29ClN8O5Cor e Forma:SolidPeso molecular:641.08Chemerin-9 (149-157)
CAS:<p>Chemerin-9, a nonapeptide C-terminal fragment of chemerin, retains full protein's activity as a ChemR23 agonist.</p>Fórmula:C54H66N10O13Pureza:98%Cor e Forma:SolidPeso molecular:1063.16Coronaridine
CAS:<p>Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.</p>Fórmula:C21H26N2O2Cor e Forma:SolidPeso molecular:338.451KIF2C-IN-1
<p>KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.</p>Fórmula:C36H39ClN4O9SCor e Forma:SolidPeso molecular:738.21263Tubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Fórmula:C22H25NO6Cor e Forma:SolidPeso molecular:399.44Jatrophone
CAS:<p>Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.</p>Fórmula:C20H24O3Cor e Forma:SolidPeso molecular:312.4T-808
CAS:<p>T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.</p>Fórmula:C17H19FN4Cor e Forma:SolidPeso molecular:298.367-Epi-10-oxo-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.</p>Fórmula:C43H51NO14Pureza:98%Cor e Forma:SolidPeso molecular:805.86Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Pureza:98%Cor e Forma:Odour SolidDynaMin inhibitory peptide, myristoylated
CAS:<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Fórmula:C61H107N19O14Pureza:98%Cor e Forma:SolidPeso molecular:1330.64SIAIS178
CAS:<p>SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).</p>Fórmula:C50H62ClN11O6S2Pureza:98.07%Cor e Forma:SolidPeso molecular:1012.68Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Fórmula:C24H20FN3O3Cor e Forma:SolidPeso molecular:417.436-Epi-ophiobolin G
<p>6-Epi-ophiobolin G (MHO7) is a marine-derived fungal metabolite that serves as an orally active Akt inhibitor capable of crossing the blood-brain barrier. It effectively inhibits the proliferation of glioblastoma (GBM) cells and promotes apoptosis. 6-Epi-ophiobolin G (MHO7) is suitable for research in glioblastoma studies.</p>Fórmula:C24H32O2Cor e Forma:SolidPeso molecular:352.24023AD57
CAS:<p>AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.</p>Fórmula:C22H20F3N7OPureza:99.05%Cor e Forma:SoildPeso molecular:455.44PROTAC BCR-ABL Degrader-1
<p>PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, promotes Bcr-Abl degradation through the ubiquitin-proteasome pathway and</p>Fórmula:C43H40N10O6Pureza:98%Cor e Forma:SolidPeso molecular:792.84PKC β pseudosubstrate
CAS:<p>Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM).</p>Fórmula:C177H294N62O38S3Pureza:98%Cor e Forma:SolidPeso molecular:3994.84(8R)-8-Hydroxyepoxyboetirane A
<p>(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.</p>Cor e Forma:Odour Solid7-Epi-docetaxel
CAS:<p>7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.</p>Fórmula:C43H53NO14Pureza:98%Cor e Forma:SolidPeso molecular:807.88AB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Fórmula:C137H215IN30O45SCor e Forma:SolidPeso molecular:3161.32Echistatin
CAS:<p>Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).</p>Fórmula:C217H341N71O74S9Pureza:98%Cor e Forma:SolidPeso molecular:5417.1Myrtucommulone
CAS:<p>Myrtucommulone is an inhibitor of the chaperonin activity of HSP60, correlating to LRP130 and LONP aggregation.</p>Fórmula:C38H52O10Pureza:98%Cor e Forma:SolidPeso molecular:668.81Filanesib TFA
CAS:<p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>Fórmula:C22H23F5N4O4SPureza:98%Cor e Forma:SolidPeso molecular:534.5Aberrant tau degrader 2
CAS:<p>Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.</p>Fórmula:C19H27N7O3SCor e Forma:SolidPeso molecular:433.528PTA001_A4
<p>PTA001_A4 (Anti-CDH17/Cadherin-17 Antibody) is a humanized antibody targeting CDH17/Cadherin-17 with anti-tumor activity and inhibits tumor cell growth.</p>Pureza:95.8% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.3% (SEC-HPLC)Cor e Forma:Odour LiquidPU-H71 HCl
CAS:<p>PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.</p>Fórmula:C18H22ClIN6O2SPureza:98.95%Cor e Forma:SoildPeso molecular:548.83DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Cor e Forma:Odour SolidAdhesamine diTFA
CAS:<p>Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.</p>Fórmula:C28H32Cl2F6N8O6S2Cor e Forma:SolidPeso molecular:825.63DPH
CAS:<p>DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.</p>Fórmula:C18H13FN4O2Pureza:99.65%Cor e Forma:SolidPeso molecular:336.32α2β1 Integrin Ligand Peptide
CAS:<p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>Fórmula:C14H22N4O9Pureza:98%Cor e Forma:SolidPeso molecular:390.35Chromeceptin
CAS:<p>Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.</p>Fórmula:C19H16F3N3OPureza:99.85%Cor e Forma:SoildPeso molecular:359.35hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Fórmula:C22H24N4OCor e Forma:SolidPeso molecular:360.45NMS-E973
CAS:<p>NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.</p>Fórmula:C22H22N4O7Pureza:99.84%Cor e Forma:SolidPeso molecular:454.43Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Fórmula:C25H41N11O8SCor e Forma:SolidPeso molecular:655.727Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Fórmula:C16H13ClN6SCor e Forma:SolidPeso molecular:356.83JG-258
CAS:<p>JG-258 is an inactive negative control for Hsp70 inhibitors [1] .</p>Fórmula:C20H22ClN3OS3Cor e Forma:SolidPeso molecular:452.06SNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Fórmula:C42H52F3N7O8Pureza:98%Cor e Forma:SolidPeso molecular:839.9Fuzapladib
CAS:<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Fórmula:C15H20F3N3O3SPureza:99.87%Cor e Forma:SoildPeso molecular:379.4α-Linolenic Acid (sodium salt)
CAS:<p>α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.</p>Fórmula:C18H29NaO2Cor e Forma:SolidPeso molecular:300.41Phosphatidylserines (bovine)
CAS:<p>Phosphatidylserine: a natural phospholipid, 2-10% in mammals, CNS-rich, synthesized in ER, involved in cell signaling, apoptosis marker.</p>Fórmula:C42H78NO10P(foroleoyl)Cor e Forma:SolidPeso molecular:788.1MS15 TFA
<p>MS15 TFA is a potent, selective AKT PROTAC degrader, effectively inhibiting AKT1, AKT2, and AKT3 with IC50 values of 798 nM, 90 nM, and 544 nM, respectively [1</p>Fórmula:C66H80F3N11O7SPureza:98%Cor e Forma:SolidPeso molecular:1228.47Vinflunine Tartrate
CAS:<p>Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.</p>Fórmula:C45H54F2N4O8·xC4H6O6Pureza:98%Cor e Forma:SolidPeso molecular:967.02Myelin Basic Protein
CAS:<p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>Fórmula:C60H103N21O17Pureza:98%Cor e Forma:SolidPeso molecular:1390.59Mps1-IN-6
<p>Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].</p>Fórmula:C35H39N9O3Cor e Forma:SolidPeso molecular:633.74MPC-0767
CAS:<p>MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.</p>Fórmula:C26H36BrN7O9S2Cor e Forma:SolidPeso molecular:734.64PDI-IN-4
<p>PDI-IN-4 (Compound 14d) is a protein disulfide isomerase inhibitor with an IC50 value of 0.48 μM. It prevents platelet aggregation and thrombosis by reducing the activation of GPIIb/IIIa, without causing significant cytotoxicity. PDI-IN-4 is applicable in thrombosis research.</p>Fórmula:C17H12F3NO2Cor e Forma:SolidPeso molecular:319.278Dihydrocephalomannine
CAS:<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Fórmula:C45H55NO14Pureza:98%Cor e Forma:SolidPeso molecular:833.928Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Fórmula:C83H127N25O34SPureza:98%Cor e Forma:SolidPeso molecular:2051.11GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Fórmula:C22H37N9O10Pureza:98%Cor e Forma:SolidPeso molecular:587.58Anti-EMMPRIN/CD147 Antibody
<p>Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Cor e Forma:Odour Liquid10-Oxo Docetaxel
CAS:<p>10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.</p>Fórmula:C43H51NO14Pureza:98%Cor e Forma:SolidPeso molecular:805.874SNIPER(ABL)-019
<p>SNIPER(ABL)-019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting a</p>Fórmula:C60H77ClN12O9SPureza:98%Cor e Forma:SolidPeso molecular:1177.85Osemitamab (FUT8-KO)
<p>Osemitamab (FUT8-KO) is a monoclonal antibody targeting claudin-18.2, expressed in CHO cells with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of fucose heightens the antibody's ADCC effect. When combined with Capecitabine and Oxaliplatin, it can be used for G/GEJ cancer research.</p>Cor e Forma:Odour LiquidFoxy-5
CAS:<p>Foxy-5 is a wnt5a peptide mimetic</p>Fórmula:C26H42N6O12S2Pureza:98%Cor e Forma:SolidPeso molecular:694.77AKT1-IN-9
<p>AKT1-IN-9 (4) is a selective inhibitor of the AKT1(E17K) mutation, exhibiting EC50 values of 9 nM in LAPC4-CR cells and 995 nM in SkBr3 cells.</p>Fórmula:C33H25FN6O4Cor e Forma:SolidPeso molecular:588.588Crosstide
CAS:<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Fórmula:C48H77N17O17Pureza:98%Cor e Forma:SolidPeso molecular:1164.23
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