Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1382 produtos de "Sinalização Citoesquelética"
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BGB659
CAS:<p>BGB659 is effective inhibitor of RAF.</p>Fórmula:C29H29F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:538.56HR22C16
CAS:<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Fórmula:C23H23N3O3Cor e Forma:SolidPeso molecular:389.45DAT1
CAS:<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Fórmula:C17H15N3O2SPureza:98%Cor e Forma:SolidPeso molecular:325.38Shz 1
CAS:<p>Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.</p>Fórmula:C13H11BrN2O3SPureza:99.57% - 99.91%Cor e Forma:SolidPeso molecular:355.21GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Fórmula:C29H37N5O2Pureza:99.547%Cor e Forma:SolidPeso molecular:487.64NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Fórmula:C18H17NO2Pureza:98%Cor e Forma:SolidPeso molecular:279.33ML-243
CAS:<p>inhibitor of cancer stem cells</p>Fórmula:C14H16N2OSPureza:98%Cor e Forma:SolidPeso molecular:260.35Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Fórmula:C24H27N5O7Pureza:98%Cor e Forma:SolidPeso molecular:497.5D011-2120
CAS:<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Fórmula:C17H15NO3Pureza:98%Cor e Forma:SolidPeso molecular:281.31JG-48
CAS:<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Fórmula:C20H16F3N3OS2Cor e Forma:SolidPeso molecular:435.49LDN-193665
CAS:<p>LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.</p>Fórmula:C15H11FN4OSPureza:98%Cor e Forma:SolidPeso molecular:314.34Diazobenzenesulfonic acid
CAS:<p>Diazobenzenesulfonic acid, white/red crystal, inhibits myosin ATPase 13 as an allosteric desensitizer.</p>Fórmula:C6H5N2O3SPureza:98%Cor e Forma:SolidPeso molecular:185.18CCT036477
CAS:<p>CCT036477 selectively inhibits Wnt/β-catenin signaling, reducing TCF/LEF transcriptional activity.</p>Fórmula:C21H18ClN3Pureza:98%Cor e Forma:SolidPeso molecular:347.84Acodazole hydrochloride
CAS:<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Fórmula:C20H20ClN5OPureza:98%Cor e Forma:SolidPeso molecular:381.86ABH Hydrochloride
CAS:<p>ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.</p>Fórmula:C6H15BClNO4Cor e Forma:SolidPeso molecular:211.45Acodazole
CAS:<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Fórmula:C20H19N5OPureza:98%Cor e Forma:SolidPeso molecular:345.4L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Fórmula:C24H34N4O4Pureza:98%Cor e Forma:SolidPeso molecular:442.55Tubulin inhibitor 7
CAS:<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Fórmula:C21H14N2O4Pureza:98%Cor e Forma:SolidPeso molecular:358.35PF-2771
CAS:<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Fórmula:C29H36ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:554.08Aha1/Hsp90-IN-1
CAS:<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Fórmula:C22H17F3N4O2Cor e Forma:SolidPeso molecular:426.39OSIP-486823
CAS:<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Fórmula:C29H28FNO4Pureza:98.59%Cor e Forma:SolidPeso molecular:473.54NVS-PAK1-C
CAS:<p>NVS-PAK1-1: potent PAK1 inhibitor, IC50 5 nM (dephosphorylated), 6 nM (phosphorylated); ATP-competitive; weaker on PAK2 (IC50 270 nM, 720 nM).</p>Fórmula:C22H23ClF3N5OCor e Forma:SoildPeso molecular:465.9EC 144
CAS:<p>EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.</p>Fórmula:C21H24ClN5O2Cor e Forma:SolidPeso molecular:413.9GF 15
CAS:<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Fórmula:C23H21ClO6Pureza:98%Cor e Forma:SolidPeso molecular:428.86CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Fórmula:C19H17N3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:351.36RUC-1
CAS:<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Fórmula:C11H15N5OSPureza:98%Cor e Forma:SolidPeso molecular:265.33NSC-668036
CAS:<p>NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.</p>Fórmula:C21H36N2O9Pureza:98%Cor e Forma:SolidPeso molecular:460.52S-methyl DM1
CAS:<p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>Fórmula:C36H50ClN3O10SPureza:98%Cor e Forma:SolidPeso molecular:752.31AG-205
CAS:<p>(rac)-AG-205 inhibits Pgrmc1, affects sterol gene INSIG1, and hinder NF-kB/BDNF/PI3K/AKT in neuronal hypoxic resistance.</p>Fórmula:C22H23ClN6OSCor e Forma:SolidPeso molecular:454.98ML-9 Free Base
CAS:<p>ML-9 suppresses MLCK, PKA, PKC (Ki: 4, 32, 54 μM), inhibits Akt kinase & STIM1, and induces autophagy.</p>Fórmula:C15H17ClN2O2SPureza:98%Cor e Forma:SolidPeso molecular:324.83Litronesib Racemate
CAS:<p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>Fórmula:C23H37N5O4S2Cor e Forma:SolidPeso molecular:511.7TOK-8801
CAS:<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Fórmula:C17H21N3OSPureza:99.97%Cor e Forma:SolidPeso molecular:315.43Creatine monohydrate
CAS:<p>Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.</p>Fórmula:C4H11N3O3Pureza:99.87%Cor e Forma:White SolidPeso molecular:149.15Amphethinile
CAS:<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Fórmula:C15H11N3SPureza:98%Cor e Forma:SolidPeso molecular:265.33CCB02
CAS:<p>CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.</p>Fórmula:C14H9N3OPureza:98.38%Cor e Forma:SolidPeso molecular:235.24Microtubule inhibitor 3
CAS:<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Fórmula:C26H23FN4O3Cor e Forma:SolidPeso molecular:458.48UR-3216
CAS:<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Fórmula:C27H29N7O7Pureza:98%Cor e Forma:SolidPeso molecular:563.56S516
CAS:<p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>Fórmula:C21H19N5O4SPureza:98%Cor e Forma:SolidPeso molecular:437.47M435-1279
CAS:<p>M435-1279 is a UBE2T inhibitor. M435-1279 blocks UBE2T-mediated degradation of RACK1, leading to inhibit the hyperactivation of Wnt/β-catenin signaling pathway.</p>Fórmula:C18H17N3O5S2Pureza:97.16%Cor e Forma:SolidPeso molecular:419.47QS11
CAS:<p>QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.</p>Fórmula:C36H33N5O2Pureza:98.59%Cor e Forma:SolidPeso molecular:567.68FAK inhibitor 2
CAS:<p>FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor with an IC50 of 0.07 nM .</p>Fórmula:C29H33F3N8O2S2Cor e Forma:SolidPeso molecular:646.75β-catenin-IN-3
CAS:<p>β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces the</p>Fórmula:C19H20Br2N2OSCor e Forma:SolidPeso molecular:484.252-Fluoropalmitic acid
CAS:<p>2-Fluoropalmitic acid, glioblastoma (GBM) by inhibiting the viability, proliferation, suppressing the expression of phosphorylated erk, CD133, and SOX-2, MMP-2.</p>Fórmula:C16H31FO2Cor e Forma:SolidPeso molecular:274.41Retaspimycin Hydrochloride
CAS:<p>Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).</p>Fórmula:C31H46ClN3O8Pureza:98%Cor e Forma:SolidPeso molecular:624.17Anticancer agent 48
CAS:<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Fórmula:C26H25N3O4Cor e Forma:SolidPeso molecular:443.49MPC-3100
CAS:<p>MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].</p>Fórmula:C22H25BrN6O4SCor e Forma:SolidPeso molecular:549.44Akt1 and Akt2-IN-1
CAS:<p>Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.</p>Fórmula:C33H29N7OCor e Forma:SolidPeso molecular:539.63Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Fórmula:C21H21N5O5Cor e Forma:SolidPeso molecular:423.42Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Fórmula:C27H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:458.55Drp1-IN-1
CAS:<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Fórmula:C22H24N8OSCor e Forma:SolidPeso molecular:448.54Microtubule inhibitor 1
CAS:<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Fórmula:C21H19NO3Pureza:98%Cor e Forma:SolidPeso molecular:333.38Tubulin inhibitor 28
CAS:<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Fórmula:C12H8Br2S2Cor e Forma:SolidPeso molecular:376.13ARUK3001185
CAS:<p>ARUK3001185 (8l): potent, selective Notum inhibitor; oral, brain-penetrant; IC50=6.7 nM; for rodent disease models.</p>Fórmula:C9H4Cl2F3N3Cor e Forma:SolidPeso molecular:282.05CHPG sodium salt
CAS:<p>CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways.</p>Fórmula:C8H7ClNNaO3Pureza:>99.99%Cor e Forma:SolidPeso molecular:223.59Valategrast
CAS:<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Fórmula:C30H32Cl3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:604.95Cardionogen 1
CAS:<p>Wnt signaling modulator</p>Fórmula:C13H14N4OSPureza:98%Cor e Forma:SolidPeso molecular:274.34EMD534085
CAS:<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Fórmula:C25H31F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:476.53Wnt/β-catenin agonist 1
CAS:<p>Wnt/β-catenin agonist 1 is an agonist of Wnt/β-catenin signalling pathway(EC50 of 0.27 μM).</p>Fórmula:C22H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:363.45BCR-ABL-IN-2
CAS:<p>BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).</p>Fórmula:C24H25Cl2N5O3Pureza:98%Cor e Forma:SolidPeso molecular:502.39Bimoclomol
CAS:<p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>Fórmula:C14H20ClN3O2Cor e Forma:SolidPeso molecular:297.78UR-1505
CAS:<p>UR-1505 is an NF-AT inhibitor that prevents T cell activation without reducing cell viability.</p>Fórmula:C10H7F5O4Pureza:98%Cor e Forma:SolidPeso molecular:286.15c-ABL-IN-2
CAS:<p>C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.</p>Fórmula:C21H20N4OCor e Forma:SolidPeso molecular:344.41AKT-IN-7
CAS:<p>AKT-IN-7 (compound 1-P1) is a potent inhibitor of AKT. AKT-IN-7 has potential for cancer research.</p>Fórmula:C23H27ClN6O2Cor e Forma:SolidPeso molecular:454.95YW1128
CAS:<p>YW1128 inhibits Wnt/β-catenin signaling (IC50=4.1 nM), reduces β-catenin, affects gene expression, and improves glucose tolerance and weight control in mice.</p>Fórmula:C20H17N5OCor e Forma:SolidPeso molecular:343.38MT-7
CAS:<p>MT-7 is a tubulin polymerization inhibitor.</p>Fórmula:C22H17N3O2Pureza:98%Cor e Forma:SolidPeso molecular:355.39Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Cor e Forma:SolidPeso molecular:430.48Anticancer agent 49
CAS:<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Fórmula:C26H25N3O4Cor e Forma:SolidPeso molecular:443.49Tubulin polymerization-IN-19
CAS:<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Fórmula:C25H25NO5Cor e Forma:SolidPeso molecular:419.47HSP90-IN-12
CAS:<p>VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.</p>Fórmula:C25H36O4Cor e Forma:SolidPeso molecular:400.55DJ101
CAS:<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Fórmula:C23H20N4O3Pureza:98%Cor e Forma:SolidPeso molecular:400.43Hsp90-IN-15
CAS:<p>Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.</p>Fórmula:C23H27F3N4Cor e Forma:SolidPeso molecular:416.48YM-01 Tosylate
CAS:<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Fórmula:C27H27N3O4S3Cor e Forma:SolidPeso molecular:553.72Displurigen
CAS:<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Fórmula:C15H10O4SPureza:98%Cor e Forma:SolidPeso molecular:286.3AKT-IN-9
CAS:<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Fórmula:C24H29ClN6OCor e Forma:SolidPeso molecular:452.98ZW4864 free base
CAS:<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Fórmula:C33H42N6O3Pureza:99.81%Cor e Forma:SolidPeso molecular:570.72Box5
CAS:<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Fórmula:C30H50N6O13S2Cor e Forma:SolidPeso molecular:766.88Malonganenone A
CAS:<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Fórmula:C26H38N4O2Cor e Forma:SolidPeso molecular:438.61Mivobulin
CAS:<p>Mivobulin is an inhibitor of tubulin .</p>Fórmula:C17H19N5O2Pureza:98%Cor e Forma:SolidPeso molecular:325.37NC043
CAS:<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Fórmula:C20H26O4Pureza:98%Cor e Forma:SolidPeso molecular:330.42KIF18A-IN-3
CAS:<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Fórmula:C28H38N4O5S2Pureza:98.45%Cor e Forma:SolidPeso molecular:574.76Zaurategrast ethyl ester
CAS:<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Fórmula:C28H29BrN4O3Pureza:98%Cor e Forma:SolidPeso molecular:549.46IMB-10
CAS:<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Fórmula:C19H15NOS2Cor e Forma:SolidPeso molecular:337.46(R)-Filanesib
CAS:<p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>Fórmula:C20H22F2N4O2SCor e Forma:SolidPeso molecular:420.48CH5138303
CAS:<p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>Fórmula:C19H18ClN5O2SPureza:98%Cor e Forma:SolidPeso molecular:415.9Tau protein aggregation-IN-1
CAS:<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Fórmula:C17H11BrN2O2Cor e Forma:SolidPeso molecular:355.19CK2-IN-9
CAS:<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Fórmula:C23H29N9OCor e Forma:SolidPeso molecular:447.54Zaurategrast ethyl ester sulfate
CAS:<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Fórmula:C56H60Br2N8O10SPureza:98%Cor e Forma:SolidPeso molecular:1197.01Tubulin polymerization-IN-27
CAS:<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Fórmula:C22H20N2O2Cor e Forma:SolidPeso molecular:344.41CK548
CAS:<p>CK548 is a novel actin-related protein (Arp)2/3 complex inhibitor.</p>Fórmula:C15H11BrClNO2SPureza:98%Cor e Forma:SolidPeso molecular:384.68SC-10
CAS:<p>SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.</p>Fórmula:C17H22ClNO2SPureza:99.24% - 99.58%Cor e Forma:SolidPeso molecular:339.88MG-2119
CAS:<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Fórmula:C27H29N5O4Cor e Forma:SolidPeso molecular:487.55AN-019
CAS:<p>AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.</p>Fórmula:C25H17F6N5OPureza:98.99%Cor e Forma:SolidPeso molecular:517.43isoCA-4
CAS:<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Fórmula:C18H20O5Cor e Forma:SolidPeso molecular:316.35Tubulin polymerization-IN-29
CAS:<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Fórmula:C25H20FNO6Cor e Forma:SolidPeso molecular:449.43BNC105P
CAS:<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Fórmula:C20H21O10PCor e Forma:SolidPeso molecular:452.34856BrCaQ
CAS:<p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>Fórmula:C18H15BrN2O3Cor e Forma:SolidPeso molecular:387.23Ellipticine quinone
CAS:<p>Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.</p>Fórmula:C15H8N2O2Cor e Forma:SolidPeso molecular:248.24Dynamin IN-1
CAS:<p>Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .</p>Fórmula:C23H24N2OCor e Forma:SolidPeso molecular:344.45PU3
CAS:<p>PU3 is an inhibitor of Hsp90.</p>Fórmula:C19H25N5O3Pureza:98%Cor e Forma:SolidPeso molecular:371.43Conteltinib
CAS:<p>Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.</p>Fórmula:C32H45N9O3SPureza:98.12% - 99.54%Cor e Forma:SolidPeso molecular:635.82para-Nitroblebbistatin
CAS:<p>para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.</p>Fórmula:C18H15N3O4Pureza:99.09% - 99.84%Cor e Forma:SolidPeso molecular:337.33Rosabulin
CAS:<p>v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.</p>Fórmula:C22H16N4O2SPureza:98.06%Cor e Forma:SolidPeso molecular:400.45JB062
CAS:<p>JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac</p>Fórmula:C19H17NO4Pureza:99.89%Cor e Forma:SolidPeso molecular:323.34Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Fórmula:C22H32N4O4Pureza:98.76%Cor e Forma:SolidPeso molecular:416.51JB002
CAS:<p>JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.</p>Fórmula:C18H15NO3Pureza:99.74%Cor e Forma:SoildPeso molecular:293.32LY3372689
CAS:<p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>Fórmula:C16H22FN5O3SPureza:99.43% - 99.53%Cor e Forma:SolidPeso molecular:383.44DCPLA-ME
CAS:<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Fórmula:C21H38O2Pureza:99.80%Cor e Forma:SolidPeso molecular:322.53CID-663143
CAS:<p>CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.</p>Fórmula:C19H18N4O2SPureza:99.68% - 99.77%Cor e Forma:SolidPeso molecular:366.44BIRT-377
CAS:<p>BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).</p>Fórmula:C18H15BrCl2N2O2Pureza:99.93%Cor e Forma:SolidPeso molecular:442.13Nilotinib hydrochloride
CAS:<p>Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.</p>Fórmula:C28H23ClF3N7OPureza:>99.99%Cor e Forma:SolidPeso molecular:565.98TCS 2210
CAS:<p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>Fórmula:C18H17N3O3Pureza:98.62%Cor e Forma:SolidPeso molecular:323.35SB-216
CAS:<p>SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.</p>Fórmula:C17H18N4O2Pureza:99.70%Cor e Forma:SolidPeso molecular:310.35AMP-PCP disodium
CAS:<p>AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.</p>Fórmula:C11H16N5Na2O12P3Pureza:99.32%Cor e Forma:SolidPeso molecular:549.17BMD4503-2
CAS:<p>BMD4503-2 is a competitive inhibitor of the LRP5/6-sclerostin complex that restores the activity of the Wnt/β-catenin signaling pathway cancer.</p>Fórmula:C26H21N5O3SPureza:99.18%Cor e Forma:SolidPeso molecular:483.54JB061
<p>JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle</p>Fórmula:C19H17NO4Pureza:99.67%Cor e Forma:SoildPeso molecular:323.34NSC668394
CAS:<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Fórmula:C17H12Br2N2O3Pureza:99.29% - 99.29%Cor e Forma:SolidPeso molecular:452.1CMPF
CAS:<p>CMPF is a microtubule protein inhibitor that can be used to study tumors.</p>Fórmula:C12H16O5Pureza:99.88%Cor e Forma:SolidPeso molecular:240.25AZ13705339
CAS:<p>AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.</p>Fórmula:C33H36FN7O3SPureza:99.77%Cor e Forma:SolidPeso molecular:629.75DZ2002
CAS:<p>DZ2002: Oral, reversible SAHH inhibitor (Ki=17.9 nM), low-toxicity, immunosuppressive, counters dermal fibrosis, used in autoimmune research.</p>Fórmula:C10H13N5O3Pureza:99.91%Cor e Forma:SolidPeso molecular:251.24JH-VIII-157-02
CAS:<p>JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.</p>Fórmula:C28H27N5O2Pureza:99.58%Cor e Forma:SolidPeso molecular:465.55Arimoclomol
CAS:<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Fórmula:C14H20ClN3O3Pureza:99.15%Cor e Forma:SolidPeso molecular:313.78ZINC00640089
CAS:<p>ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.</p>Fórmula:C20H13F3N2O2Pureza:98.41% - 99.80%Cor e Forma:SolidPeso molecular:370.32DM1-SMe
CAS:<p>DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.</p>Fórmula:C36H50ClN3O10S2Pureza:99.61%Cor e Forma:SolidPeso molecular:784.38Defactinib hydrochloride
CAS:<p>Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.</p>Fórmula:C20H22ClF3N8O3SPureza:98.06% - 98.78%Cor e Forma:SolidPeso molecular:546.95PPY A
CAS:<p>PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cells</p>Fórmula:C22H20N4O2Pureza:98.77%Cor e Forma:SolidPeso molecular:372.42Iroxanadine
CAS:<p>Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in</p>Fórmula:C14H20N4OPureza:98.04% - 99.04%Cor e Forma:SolidPeso molecular:260.33Tubulin inhibitor 8
CAS:<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Fórmula:C21H14N2O3Pureza:98.51% - 99.87%Cor e Forma:SolidPeso molecular:342.35Elsibucol
CAS:<p>Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant,</p>Fórmula:C35H54O4S2Pureza:99.73%Cor e Forma:SolidPeso molecular:602.93AKT-IN-6
CAS:<p>AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.</p>Fórmula:C22H20FN5OPureza:98.68%Cor e Forma:SolidPeso molecular:389.43Terflavoxate
CAS:<p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>Fórmula:C26H29NO4Pureza:98%Cor e Forma:SolidPeso molecular:419.51Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Fórmula:C27H27F2NO6Pureza:99.16%Cor e Forma:SolidPeso molecular:499.5SNX0723
CAS:<p>SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.</p>Fórmula:C22H26FN3O3Pureza:99.85%Cor e Forma:SolidPeso molecular:399.46Erbulozole
CAS:<p>Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.</p>Fórmula:C24H27N3O5SPureza:99.88%Cor e Forma:SolidPeso molecular:469.55Bis-T-23
CAS:<p>Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative.</p>Fórmula:C23H20N4O8Pureza:96.81% - 98.13%Cor e Forma:SolidPeso molecular:480.43Dynapyrazole A
CAS:<p>Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).</p>Fórmula:C20H12ClIN4OPureza:98.01%Cor e Forma:SolidPeso molecular:486.69UMK57
CAS:<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Fórmula:C17H17N3SPureza:99.81%Cor e Forma:SolidPeso molecular:295.4EMT inhibitor-1
CAS:<p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>Fórmula:C12H12Cl2N2O2SPureza:99.53%Cor e Forma:SolidPeso molecular:319.21JG-231
CAS:<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Fórmula:C22H18BrCl2N3OS4Pureza:99.79%Cor e Forma:SolidPeso molecular:619.47ASN90
CAS:<p>ASN90 is a specific, orally active inhibitor of the O-GlcNAcase (OGA) enzyme, demonstrating an IC50 of 10.2 nM.</p>Fórmula:C17H21N5O3SCor e Forma:SolidPeso molecular:375.45AKT-IN-13
CAS:<p>AKT-IN-13 inhibits Akt1, Akt2, Akt3 (IC50: 1.6, 2.4, 0.3 nM); used in cancer research.</p>Fórmula:C24H31ClN6O2Cor e Forma:SolidPeso molecular:470.99ICAM-1-IN-1
CAS:<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Fórmula:C15H11BrN2O2SPureza:99.67%Cor e Forma:SolidPeso molecular:363.23ATN-161
CAS:<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Fórmula:C23H35N9O8SPureza:98%Cor e Forma:SolidPeso molecular:597.64MAO A/HSP90-IN-2
CAS:<p>MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.</p>Fórmula:C25H31ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:458.98VTX-27
CAS:<p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>Fórmula:C20H24ClFN6OPureza:99.84%Cor e Forma:SolidPeso molecular:418.9WAY 316606 hydrochloride
CAS:<p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>Fórmula:C18H20ClF3N2O4S2Cor e Forma:SolidPeso molecular:484.94CCT251455
CAS:<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Fórmula:C26H26ClN7O2Pureza:99.1% - 99.1%Cor e Forma:SolidPeso molecular:503.98TAK 029
CAS:<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Fórmula:C19H23N5O7Cor e Forma:SolidPeso molecular:433.42JG-23
CAS:<p>JG-23, a 4-chloro-modified analog, effectively induces t-tau degradation and demonstrates robust metabolic stability, exhibiting an extended half-life (T1/2) of</p>Fórmula:C19H16ClN3OS2Cor e Forma:SolidPeso molecular:401.93Tubulin polymerization-IN-52
CAS:<p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>Fórmula:C21H18F3N5O3Cor e Forma:SolidPeso molecular:445.39Oxaline
CAS:<p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>Fórmula:C24H25N5O4Cor e Forma:SolidPeso molecular:447.49MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Cor e Forma:SolidPeso molecular:1115.71β-Catenin modulator-2
CAS:<p>β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C20H18Cl2N2O3SCor e Forma:SolidPeso molecular:437.34CNS-11
CAS:<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Fórmula:C25H21N3O2Cor e Forma:SolidPeso molecular:395.45PTK7/β-catenin-IN-1
CAS:<p>PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].</p>Fórmula:C22H16N2O2Cor e Forma:SolidPeso molecular:340.382BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Fórmula:C32H26Cl2FN7O3Pureza:98%Cor e Forma:SolidPeso molecular:646.5BX-2819
CAS:<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Fórmula:C21H24N4O4SPureza:98%Cor e Forma:SolidPeso molecular:428.51UU-T01
CAS:<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Fórmula:C10H10N6OCor e Forma:SolidPeso molecular:230.23Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Pureza:95%Cor e Forma:Liquidβ-Catenin modulator-5
CAS:<p>β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H22N2O2SCor e Forma:SolidPeso molecular:366.48Flavokawain 1i
CAS:<p>Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.</p>Fórmula:C21H18O4Cor e Forma:SolidPeso molecular:334.37AKT-I-1
CAS:<p>AKT-I-1 is a selective and reversible inhibitor of Akt1.</p>Fórmula:C22H30N6Pureza:99.89%Cor e Forma:SolidPeso molecular:378.51G-5555
CAS:<p>G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).</p>Fórmula:C25H25ClN6O3Pureza:99.76% - 99.84%Cor e Forma:SolidPeso molecular:492.96β-Catenin modulator-1
CAS:<p>β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].</p>Fórmula:C21H28N2O4SCor e Forma:SolidPeso molecular:404.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Fórmula:C29H38N4O3Pureza:98%Cor e Forma:SolidPeso molecular:490.64β-Catenin modulator-4
CAS:<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Fórmula:C21H21ClN2O2SCor e Forma:SolidPeso molecular:400.92Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Fórmula:C28H31ClN6O3Cor e Forma:SolidPeso molecular:535.04TAS0612
CAS:<p>TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].</p>Fórmula:C27H34F3N9O2Pureza:98%Cor e Forma:SolidPeso molecular:573.61PAK1-IN-1
CAS:<p>PAK1-IN-1: PAK1 inhibitor, IC50 9.8 nM, hinders tumor cell migration and invasion dose-dependently.</p>Fórmula:C26H20ClN5O2Cor e Forma:SolidPeso molecular:469.92Pivanex
CAS:<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Fórmula:C10H18O4Pureza:≥98%Cor e Forma:SolidPeso molecular:202.25ALM301
CAS:<p>ALM301: oral AKT inhibitor targeting AKT1, AKT2, AKT3; blocks AKT phosphorylation, curbs cancer cell growth.</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Dolastatinol
CAS:<p>Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.</p>Fórmula:C43H70N6O7SCor e Forma:SolidPeso molecular:815.12αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Fórmula:C29H38N4O4Pureza:98%Cor e Forma:SolidPeso molecular:506.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Fórmula:C22H24F3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:451.44Valecobulin hydrochloride
CAS:<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Fórmula:C26H29ClN6O5SPureza:99.52%Cor e Forma:SolidPeso molecular:573.06CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Fórmula:C24H29N7OPureza:98%Cor e Forma:SolidPeso molecular:431.53Paluratide
CAS:<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Fórmula:C73H105F5N12O12Pureza:98.70%Cor e Forma:SolidPeso molecular:1437.68Levocabastine
CAS:<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Fórmula:C26H29FN2O2Cor e Forma:SolidPeso molecular:420.52ER degrader 7
CAS:<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Fórmula:C33H31F4N3O5SSeCor e Forma:SolidPeso molecular:736.63Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Fórmula:C26H25BrN4O3Pureza:98%Cor e Forma:SolidPeso molecular:521.41Phenamacril
CAS:<p>Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.</p>Fórmula:C12H12N2O2Pureza:99.52%Cor e Forma:SolidPeso molecular:216.24HSP90-IN-29
CAS:<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Fórmula:C19H20ClN3O4Cor e Forma:SolidPeso molecular:389.83Akt-I-1,2
CAS:<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Fórmula:C23H22ClN3Pureza:99.95%Cor e Forma:SolidPeso molecular:375.893,4',5-Trismethoxybenzophenone
CAS:<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Fórmula:C16H16O4Cor e Forma:SolidPeso molecular:272.3GRP78-IN-2
CAS:<p>GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.</p>Fórmula:C29H29NO6Cor e Forma:SolidPeso molecular:487.54Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Fórmula:C22H37ClN2O5SPureza:98%Cor e Forma:SolidPeso molecular:477.06Iroxanadine sulfate
CAS:<p>Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Fórmula:C14H22N4O5SCor e Forma:SolidPeso molecular:358.41Integrin Antagonists 27
CAS:<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Fórmula:C24H20N4O5Cor e Forma:SolidPeso molecular:444.44PAK4-IN-1
CAS:<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Fórmula:C26H30ClN7O5Cor e Forma:SolidPeso molecular:556.01Porcn-IN-2
CAS:<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Fórmula:C24H17F3N6OCor e Forma:SolidPeso molecular:462.43αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Fórmula:C21H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:386.49Risvodetinib
CAS:<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Fórmula:C33H34N8O2Cor e Forma:SolidPeso molecular:574.68Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Cor e Forma:LiquidLitronesib
CAS:<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Fórmula:C23H37N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:511.7Tubulin inhibitor 25
CAS:<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Fórmula:C26H22O8Cor e Forma:SolidPeso molecular:462.45β-catenin-IN-6
CAS:<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Fórmula:C22H19ClN6OCor e Forma:SolidPeso molecular:418.88KIF18A-IN-7
CAS:<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Fórmula:C27H35N3O5S2Cor e Forma:SoildPeso molecular:545.71MAO A/HSP90-IN-1
CAS:<p>MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.</p>Fórmula:C24H29ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:444.95LY2780301
CAS:<p>LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.</p>Fórmula:C25H27F4N7OCor e Forma:SolidPeso molecular:517.52KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Cor e Forma:SolidPeso molecular:356.41Lotrafiban hydrochloride
CAS:<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Fórmula:C23H33ClN4O4Cor e Forma:SolidPeso molecular:464.99
