Sinalização Citoesquelética
Os inibidores de sinalização do citoesqueleto são compostos que interrompem as vias de sinalização que regulam o citoesqueleto, crucial para a forma celular, motilidade, divisão e transporte intracelular. Esses inibidores são usados para estudar a dinâmica das proteínas do citoesqueleto, como actina e tubulina, e seu papel em processos como migração celular, adesão e metástase do câncer. Os inibidores de sinalização do citoesqueleto são valiosos na pesquisa em biologia celular, câncer e neurobiologia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de sinalização do citoesqueleto de alta qualidade para apoiar sua pesquisa nessas áreas.
Foram encontrados 1383 produtos de "Sinalização Citoesquelética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
GMB-475
CAS:<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Cor e Forma:SolidPeso molecular:861.93Pep2m, myristoylated acetate
<p>Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.</p>Fórmula:C65H122N18O16SPureza:99.62%Cor e Forma:SolidPeso molecular:1443.96Teduglutide acetate
<p>Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.</p>Fórmula:C166H256N44O56SPureza:97.39%Cor e Forma:SoildPeso molecular:3812.13Vodobatinib
CAS:<p>Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.</p>Fórmula:C27H20ClN3O2Pureza:99.06% - 99.55%Cor e Forma:SolidPeso molecular:453.92Decursin
CAS:<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Fórmula:C19H20O5Pureza:97.22% - 99.84%Cor e Forma:SolidPeso molecular:328.36Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Cor e Forma:White To Off-White PowderPeso molecular:521.68Pimitespib
CAS:<p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>Fórmula:C25H26N8OPureza:99.22% - 99.49%Cor e Forma:SolidPeso molecular:454.53Ζ-Stat
CAS:<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Fórmula:C10H8O10S3Pureza:99.85%Cor e Forma:SolidPeso molecular:384.36Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Cor e Forma:SolidPeso molecular:292.35GLPG0187
CAS:<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Fórmula:C29H37N7O5SPureza:99.4% - 99.70%Cor e Forma:SolidPeso molecular:595.71Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Fórmula:C21H18ClNO4Pureza:95% - 99.19%Cor e Forma:Yellow To Orange SolidPeso molecular:383.83Pamidronic acid
CAS:<p>Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells</p>Fórmula:C3H11NO7P2Pureza:97.72%Cor e Forma:SolidPeso molecular:235.07LP-261
CAS:<p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>Fórmula:C22H19N3O4SPureza:99.91%Cor e Forma:SolidPeso molecular:421.47VER-82576
CAS:<p>VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.</p>Fórmula:C21H23Cl2N5O2SPureza:97.31% - 99.85%Cor e Forma:SolidPeso molecular:480.41Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Cor e Forma:White SolidPeso molecular:327.83Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Fórmula:C16H18N2O2SPureza:98.07%Cor e Forma:SolidPeso molecular:302.39PF-562271 hydrochloride
CAS:<p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>Fórmula:C21H20F3N7O3SHClPureza:97.08%Cor e Forma:SolidPeso molecular:543.95R59949
CAS:<p>R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.</p>Fórmula:C28H25F2N3OSPureza:97.04%Cor e Forma:SolidPeso molecular:489.58T807
CAS:<p>T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).</p>Fórmula:C16H10FN3Pureza:99.72%Cor e Forma:SolidPeso molecular:263.27Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Pureza:98.00%Cor e Forma:LiquidPeso molecular:N/AAMP-945
CAS:<p>AMP-945 is a proprietary focal adhesion kinase (FAK) inhibitor.</p>Fórmula:C28H32F3N5O2Pureza:99.76%Cor e Forma:SolidPeso molecular:527.58Empesertib
CAS:<p>Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.</p>Fórmula:C29H26FN5O4SPureza:97.45% - 99.4%Cor e Forma:SolidPeso molecular:559.61(E)-Akt inhibitor-IV
CAS:<p>(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.</p>Fórmula:C31H29IN4SPureza:99.74% - 99.9%Cor e Forma:SolidPeso molecular:616.56GRGDSP acetate(91037-75-1 free base)
<p>GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.</p>Fórmula:C24H41N9O12Pureza:99.77%Cor e Forma:SolidPeso molecular:647.64PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Fórmula:C21H22N6OPureza:98.82%Cor e Forma:SolidPeso molecular:374.44GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Cor e Forma:SolidPeso molecular:592.13Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Cor e Forma:SolidPeso molecular:360.31iRGD peptide
CAS:<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Fórmula:C35H57N13O14S2Pureza:98.77%Cor e Forma:SolidPeso molecular:948.04TRC051384
CAS:<p>TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.</p>Fórmula:C25H31N5O4Pureza:98.79%Cor e Forma:SolidPeso molecular:465.54Carbenoxolone disodium
CAS:<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Fórmula:C34H48Na2O7Pureza:99.69%Cor e Forma:SolidPeso molecular:614.72TRC051384 HCl
CAS:<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Fórmula:C25H32ClN5O4Pureza:97.55%Cor e Forma:SolidPeso molecular:502.01Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Cor e Forma:White SolidPeso molecular:495.071,2-Dimyristoyl-sn-glycerol
CAS:<p>1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..</p>Fórmula:C31H60O5Pureza:99.96%Cor e Forma:White Powder With LumpsPeso molecular:512.81BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Cor e Forma:SolidPeso molecular:708.8A-286982
CAS:<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Fórmula:C24H27N3O4SPureza:97.81%Cor e Forma:SolidPeso molecular:453.55CTX-0294885 hydrochloride
<p>CTX-0294885 hydrochloride inhibits 235 kinases, affects AKT family, and aids in studying kinome-related diseases.</p>Fórmula:C22H25Cl2N7OCor e Forma:SolidPeso molecular:474.39PKC-θ inhibitor hcl
CAS:<p>PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).</p>Fórmula:C20H26ClF3N6O3Pureza:98.93%Cor e Forma:SolidPeso molecular:490.91GNF-2
CAS:<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Fórmula:C18H13F3N4O2Pureza:98.17% - ≥95%Cor e Forma:SolidPeso molecular:374.32K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Cor e Forma:SolidPeso molecular:277.34PRE-084 hydrochloride
CAS:<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Fórmula:C19H28ClNO3Pureza:99.54%Cor e Forma:SolidPeso molecular:353.88α2β1 Integrin Ligand Peptide acetate
<p>α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.</p>Fórmula:C16H26N4O11Pureza:98.46%Cor e Forma:SolidPeso molecular:450.4Tetradecyltrimethylammonium bromide
CAS:<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Fórmula:C17H38BrNPureza:99.80%Cor e Forma:SolidPeso molecular:336.39CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Cor e Forma:SolidPeso molecular:500.33ZIP acetate(863987-12-6 free base)
<p>ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.</p>Fórmula:C92H158N30O19Pureza:94.68%Cor e Forma:SolidPeso molecular:1988.43GW406108X(Z/E)
CAS:<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Fórmula:C20H11Cl2NO4Pureza:98.23%Cor e Forma:SolidPeso molecular:400.21NSC45586
CAS:<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Fórmula:C20H18N6NaO3Pureza:99.31%Cor e Forma:SolidPeso molecular:413.4SEW2871
CAS:<p>SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.</p>Fórmula:C20H10F6N2OSPureza:99.96%Cor e Forma:White SolidPeso molecular:440.36PF-04691502
CAS:<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Fórmula:C22H27N5O4Pureza:96.27% - ≥95%Cor e Forma:SolidPeso molecular:425.48CTX-0294885
CAS:<p>CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.</p>Fórmula:C22H24ClN7OPureza:98.73% - ≥95%Cor e Forma:SolidPeso molecular:437.93SU6656
CAS:<p>SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.</p>Fórmula:C19H21N3O3SPureza:98.21% - 98.73%Cor e Forma:SolidPeso molecular:371.45
