Haletos orgânicos

<p>Applications 1-(4-CHLOROPHENYL)CYCLOBUTANAMINE HYDROCHLORIDE (cas# 1228878-71-4) is a useful research chemical.<br></p>

<p>Applications Used for preparation of substituted thiazolesulfonamides as antiglaucoma agents.<br>References Boie, Y., et al.: Eur. J. Pharmacol., 340, 227 (1997), Boyer, F., et al.: J. Med. Chem., 43, 843 (2000), Lipinski, C., et al.: J. Pharmacol. Toxicol. Methods, 44, 235 (2000), Kimura, M., et al.: Endocrinology, 142, 4428 (2001),<br></p>

<p>Applications 4-Chloro-3-fluorobenzoic Acid is a very useful precursor. It is a reagent used to synthesize 6-Hydroxy Albaconazole (H761395) which is a metabolite of Albaconazole (A511450), an antifungal agent as neuroprotectant.<br>References Pujol, I., et al.: J. Antimicrob. Chemother., 39, 163 (1997), Gilgado, F., et al.: J. Clin. Microbiol., 43, 4930 (2005), Raad, I., et al.: Clin. Infect. Dis., 42, 1398 (2006), Nucci, M., et al.: Clin. Microbiol. Rev., 20, 695 (2007),<br></p>

<p>Applications 2,6-Difluorobenzyl alcohol<br></p>

<p>Applications 2-Bromo-4-chloroanisole has been used as a reactant in the preparation of naphthyl phenyl ethers as nonnucleoside HIV-1 reverse transcriptase inhibitors.<br>References Gu, S., et. al.: Bioorg. Med. Chem., 19, 4220 (2011)<br></p>

<p>Applications Substrate specificity of haloalkane dehalogenases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),<br></p>

<p>Applications 3-Aminobenzotrifluoride is a known human toxin that can cause bacterial mutation and hepatocyte unscheduled DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reinhold, D., et al.: T. ASAE, 49, 2077 (2006); Thompson, C., et al.: Environ. Mutagen., 5, 803 (1983)<br></p>

<p>Applications 2-Chloro-p-xylene is a toxic compound found in algae.<br>References Tsai, K.; et al.: Environ. Toxicol. Chem., 26, 1931 (2007).<br></p>

<p>Applications 3-Bromo-4-isopropylbenzoic acid<br></p>

<p>Applications N-(4-Chlorophenyl)-2,6-Difluorobenzamide (cas# 122987-01-3) is a useful research chemical.<br></p>

<p>Applications 1-Bromo-4-ethylbenzene is organo bromide with flame retardant properties.<br>References Day, M. et al.: J. Fire Sci., 1, 255 (1983);<br></p>

<p>Applications (Chloromethyl)cyclopropane is a used as a reagent to synthesize 6-alkylamino-9-alkylpurines, compounds that have potential to be antipsychotic agents. (Chloromethyl)cyclopropane is also used as a reagent to prepare acylmorphinans, a class of compounds that have analgesic effects in rats.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kelley, J., et al.: J. Med. Chem., 40, 3207 (1997); Mohacsi, E., et al.: J. Med. Chem., 28, 1177 (1985)<br></p>

<p>Applications 3-amino-5-chloro-1,3-dihydro-2H-indol-2-one hydrochloride (cas# 1104895-64-8) is a useful research chemical.<br></p>

<p>Applications Reagent used in the preparation of fluorescent dyes and indicators.<br>References Link, J., et al.: J. Med. Chem., 48, 5295 (2005), Martin, V., et al.: Bioorg. Med. Chem. Lett., 15, 1851 (2005),<br></p>

<p>Applications 2-[(Benzyloxycarbonyl)amino]-4,4,4-trifluorobutanoic acid is used in the preparation of benzamides and nicotinamides as spleen tyrosine kinase inhibitors.<br>References Jia, Z., et al.: PCT Int. Appl., 359 (2012)<br></p>

<p>Applications 4-(4-Fluorophenyl)aniline<br></p>

<p>Applications 1-Bromo-2,3-dimethyl-benzene is a useful synthetic intermediate. It is used as a reagent to synthesize vaniprevir. It can also be used to synthesize various piperidine derivatives, e.g., 4-arylpiperidines and cinnamoylpiperidine, which are 5-HT2C agonist and PAR1 antagonist, respectively.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Song, Z., et a;.: J. Org. Chem., 76, 9553 (2011); Conway, R., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012); Planty, B., et al.: Bioorg. Med. Chem. Lett., 20, 1735 (2010)<br></p>

<p>Applications tert-Butyl Bromoacetate is a halogenated t-butyl acetate commonly used as an alkylating agent. tert-Butyl Bromoacetate is used in the synthesis of collagenase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Steinman, D.H. et al.: Bioorg. Med. Chem. Lett., 8, 2087 (1998); Fray, M.J. et al.: J. Med. Chem., 46, 3514 (2003): Neri, P. et al.: J. Org. Chem., 59, 3880 (1994);<br></p>

<p>Applications o-Iodochlorobenzene is a building block that has been used as a reactant for the synthesis of biaryl derivatives of seasamol used for their antioxidant activity against DPPH radical.<br>References Rodriguez, S.A., et. al.: Australian J. Chem., 66, 1334 (2013)<br></p>

<p>Applications 1-Bromo-2,3-dimethyl-2-butene is used as a reagent in the synthesis of (+)-virantmycin (CAS#: 104871-14-9).<br>References Morimoto, Y., et al.: Tetrahedron, 52, 10631 (1996)<br></p>

<p>Applications 3-Bromo-benzenebutanoic Acid is a reactant used in the preparation of pyrrolo-(di)-benzazocinones via an intramolecular cyclization of N-acyliminium ions formed from 4,4-diethyoxybutyl amides (Erratum)<br>References King, F.D., et al.: Org. Biomol. Chem., 7, 5271 (2009); King, F.D., et al.: Org. Biomol. Chem., 7, 167 (2009)<br></p>

<p>Stability Moisture Sensitive<br>Applications Chlorocarbonylsulfenyl chloride is a useful research chemical for organic synthesis and other chemical processes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sorra, K., et al.: Int. J. Mol. Sci., 15, 16500 (2014); Gurjar, A. S., et al.: Bioorg. Chem., 57, 90 (2014); Enache, L., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2005)<br></p>

<p>Applications 4,5-Dichloro-phenylenediamine (cas# 5348-42-5) is a compound useful in organic synthesis.<br></p>

<p>Stability Moisture Sensitive<br>Applications 1,5-Dichlorohexamethyltrisiloxane is a useful chemical in organic synthesis.<br> E0<br>References Tagne Kuate, Alain C., et al.: J. of Organometallic Chem., 751, 628-637 (2014);Basenko, S. V., et al.: Doklady Chem., 450(1), 135-138 (2013);Gao, Fei, et al.: Polymer Journal, 43(2), 136-140 (2011)<br></p>

<p>Applications 2-Fluoro-5-(trifluoromethyl)benzoic acid<br></p>

<p>Applications 2-Amino-3-bromo-5-chlorobenzoic Acid is used as a starting material in the synthesis of a series of 3-(2-(2-methoxyphenyl)-2-oxoethyl) quinazolinone derivatives, which showed anticoccidial activity against Eimeria tenella in chicken.<br>References Ye, Changwen., et al.: Pestic. Biochem. Phys., 97(3), 194-198 (2010)<br></p>

<p>Stability Moisture Sensitive<br>Applications Oleyl Chloride is used as a chemical reagent in the preparation of Vitamin E analogs as well as antiviral nucleoside phosphoramidate prodrugs used in the treatment of HIV and HBV.<br>References Cho, J. et al.: Bioorg. Med. Chem., 22, 6665 (2014); Iwata, R. et al.: Bioorg. Med. CHem. Lett., 25, 815 (2015);<br></p>

<p>Applications 2-[(2-fluorophenyl)sulfanyl]acetic acid (cas# 705-02-2) is used in the preparation of phenylsulfanylalkylcarboxylic acid compositions, useful for the delivery of active agents.<br>References Wang, N. F., et al.: PCT Int. Appl. 118 pp. (2008)<br></p>

<p>Applications o-Chloramine T (cas# 110076-44-3) is a useful research chemical.<br></p>

<p>Applications Dibromoisocyanuric acid is a bromine compound with a superior bactericidal activity.<br>References Gottardi, W., et al.: J. Appl. Microbiol., 116, 1427 (2014)<br></p>

<p>Applications 5-​Bromopentyl Acetate is used to model the toxicity of haloesters on marine bacterium such as Vibrio fischeri.<br>References Cornin, M.T.D, et. al.: SAR QSAR Environ. Res., 11, 301 (2000)<br></p>

<p>Applications 2-Bromo-1,4-dichlorobenzene is a reactant used in the synthesis of C-13 and C-14-labeled versions of the investigational proteasome inhibitor MLN9708.<br>References Plesescu, M., et. al.: J. Labelled Compd. Rad., 56, 464 (2013)<br></p>

<p>Applications 3-Bromothioanisole (cas# 33733-73-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ethyl (Z)-3-(Dimethylcarbamoylamino)-4,4,4-trifluoro-but-2-enoate is an intermediate in the synthesis of Tiafenacil (T436300), which is a uracil herbicide used as a pesticide for the prevention and control of plants.<br>References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEV<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Adams, M. et al.: Synth. Comm., 29, 2419 (1999); Foroumadi, A. et al.: Arch. Pharm. Res., 30, 138 (2007);<br></p>

<p>Applications 1-Bromo-3,4-dichlorobenzene<br></p>

Tetrafluoroethane, also known as Freon-12, is a chlorofluorocarbon that has been identified as a potent greenhouse gas. Tetrafluoroethane is a byproduct of the industrial production of fluorochemicals, and its disposal in landfill sites has led to soil contamination. 1,2-Dichloro-2-iodo-1,1,2-trifluoroethane (CIF) is a halogenated hydrocarbon that can be synthesized from tetrafluoroethane using an electrochemical process. CIF is used as a catalyst for telomerization reactions such as the synthesis of polyethylene terephthalate (PET). The efficiency of this reaction increases with higher temperatures and lower potentials. This is due to the increased ionization energy which leads to more efficient electron transfer. The reaction mechanism for the telomerization of furan with ethylene glycol with CIF as catalyst at high

1-(2,4-Dichlorophenyl)piperazine is a reuptake inhibitor of the monoamine neurotransmitters serotonin, dopamine, and norepinephrine. It blocks the reuptake of these neurotransmitters by binding to their transporters in the presynaptic neuron. 1-(2,4-Dichlorophenyl)piperazine also has inhibitory activity against carboxamides and docking inhibitors. This drug can be used in treatment of depression and anxiety disorders.

<p>Please enquire for more information about 2-(Trifluoroacetamido)Ethylamine Hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Chloro-5-(trifluoromethyl)pyridin-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Chloro-5H-pyrimido[5,4-b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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<p>Please enquire for more information about (D-His1)-Exenatide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

4-Bromo-2-methylbenzoic acid is a nucleophilic compound that can be used for the synthesis of esters, amides and peptides. It is also an intermediate in the synthesis of 4-bromo-2-methylbenzoic acid methyl ester, which can be used as a cardiac marker. The hydroxylamine group on this molecule reacts with electrophiles such as benzoate to form bromoacetic acid derivatives. This reaction is catalyzed by palladium and other metals. The multidimensional nature of this reaction means it can be used for cross-coupling reactions.

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<p>5-Bromo-6-methylpyrimidine-2,4(1H,3H)-dione is an immunosuppressive drug that belongs to the class of hydantoins. It can be used to treat a variety of diseases associated with immunodeficiency including AIDS. 5-Bromo-6-methylpyrimidine-2,4(1H,3H)-dione inhibits viral replication by alkylating nucleotides and DNA synthesis at the GTPase level. The amide group in the molecule is responsible for this property. Kinetics studies have shown that the rate of hydrolysis of 5-bromo-6-methylpyrimidine-2,4(1H,3H)-dione depends on the pH and temperature of solution.</p>

<p>N-Bromosuccinimide is a reactive chemical that is used in the manufacture of pharmaceutical preparations. It reacts with methyl ketones to form bromoketones, which can be detected by the chemiluminescence method. Although there is no direct evidence for the mechanism of this reaction, it is thought that there are two possible pathways. The first pathway involves a series of reactions involving activated methylene compounds and quinoline derivatives, while the second pathway involves transfer reactions from n-dimethyl formamide to lysine residues in proteins. The second pathway has been shown to be dominant in aerobacter aerogenes.</p>

Ethyl hexafluOrOglutaryl chlOride is a tricyclic antidepressant drug that belongs to the class of drugs known as monoamine oxidase inhibitors. It can be used to treat depression and other mood disorders. Ethyl hexafluOrOglutaryl chlOride inhibits the enzyme monoamine oxidase, which is responsible for breaking down amines such as serotonin and norepinephrine in the brain. This leads to an increase in the levels of these neurotransmitters, which are important for mood regulation. The presence of this drug in urine samples can be detected using a spectrometric analytical method. It can also be detected in blood samples by chemical ionization with gas chromatography-mass spectrometry (GC-MS).

<p>4-Iodobenzyl bromide is an aromatic hydrocarbon that inhibits the activity of aromatic hydroxylase, an enzyme responsible for the metabolism of aromatic compounds. It is a synthetic compound that has been used in research to study the metabolism of aromatic amino acids. 4-Iodobenzyl bromide has been shown to be effective in inhibiting the synthesis of diphenyl sulfoxide and chloride by human kidney cells in vitro. The inhibition of this reaction leads to a decrease in the concentration of these substances in urine samples. It also inhibits silver trifluoromethanesulfonate, which may be due to its ability to react with chloride ions. This product is soluble in organic solvents such as chloroformate and can be used as a functional group.</p>

5-Bromo-2,2-difluoro-1,3-benzodioxole is an industrial chemical that can be used in the production of cuprous cyanide. It is made by reacting methanol with hydrogen fluoride and catalysts. The product yield is high and the reaction process is efficient. 5-Bromo-2,2-difluoro-1,3-benzodioxole can be used to produce 1-4c alkyl cyanides by esterification. The catalyst for this reaction is typically a fluoride salt or a metallic salt such as zinc chloride or ferric chloride. This chemical can also be used to produce cyanide from hydrogen cyanide or hydrocyanic acid. The large scale process flow for this chemical involves use of a catalyst, such as sodium hydroxide, potassium hydroxide, or calcium oxide.

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<p>4,4,4-Trifluorovaline is a chemical compound with a trifluoromethyl group that can be synthesized in an efficient method. It has been shown to have the ability to stabilize proteins and enzymes in recombinant systems. The enolate of 4,4,4-trifluorovaline reacts with amides to form allylations. The stereoselective synthesis of 4,4,4-trifluorovaline isomers produces two diastereoisomers that are separated by either chiral chromatography or crystallization. These methods allow for the introduction of 4,4,4-trifluorovaline into cellular systems without affecting the stability of the protein or enzyme.</p>

3-Nitro-4-chloro-benzotrifluoride is a nucleophilic reagent that reacts with aryl chlorides, such as phenoxazine and chloride, to give the corresponding nitro compounds. The reaction yield is dependent on the solvent, with higher yields obtained in n-dimethyl formamide than in dichloromethane. 3-Nitro-4-chloro-benzotrifluoride has been investigated for its potential use in cancer therapy. It inhibits the proliferation of a number of cancer cells, including resistant mutants. The deuterium isotope effect has also been used to determine the mechanism of action of 3-nitro-4-chloro benzo trifluoride.

(R)-(+)-(2,2-Bis(Diphenylphosphino)-1,1-binaphthyl)palladium(II)chloride is a colorless solid that can be made into a crystalline form. It has a molecular weight of 518.8 g/mol and the chemical formula C12H14P4Cl2. The compound has four asymmetric carbon atoms and two stereocenters in the molecule. This compound is used as a catalyst for organic reactions and in the synthesis of other compounds. (R)-(+)-(2,2-Bis(Diphenylphosphino)-1,1-binaphthyl)palladium(II)chloride is soluble in ethanol and ether but insoluble in water. It reacts with oxygen to produce phosphorous acid and hydrogen chloride gas. This compound has been shown to have nuclear magnetic resonance spectra at room temperature with chemical shifts (

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2-Bromo-4-methylacetophenone is a synthetic compound that inhibits bacterial growth through acetylation of the aromatic ring. It is used in the synthesis of imidazolidinones, which are a class of antibacterial drugs. 2-Bromo-4-methylacetophenone has shown inhibitory activity against MCF-7 breast carcinoma cells and mononuclear cells. It also has been synthesized from phenacyl bromide and potassium carbonate in anhydrous conditions. The crystal system for 2-bromo-4-methylacetophenone is tetragonal with space group P42/mnm.

β-ketone analogue of methamphetamine and has comparable effects on monoamine upt

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3-Bromopyridine is a colorless liquid that is soluble in water and methanol. It has a chemical ionization mass spectrum with hydrogen bonding interactions, which are shown by the nitrogen atoms. 3-Bromopyridine reacts with amines to form nitroso compounds and has transport properties that are dependent on pH. 3-Bromopyridine has been shown to be a metastable substance, which means it can be isolated in a yield of greater than 50%. 3-Bromopyridine is soluble in alkaline solutions, but decomposes at high temperatures. The solution turns red when phosphotungstic acid is added and it gives an orange precipitate when hydrochloric acid is added. The solution turns yellow when sodium hydroxide is added. 3-Bromopyridine can be detected by its nmr spectra and kinetic energy measurements.

2-Bromo-6-methoxypyridin-3-amine is a perovskite that has been shown to have a high photoluminescence quantum yield and can be used in solar cells. This compound interacts with both the ligands and the acceptors, boosting the efficiency of these compounds. The 2-bromo-6 methoxypyridin-3 amine is a semiconductor with an electron affinity of 1.9 eV and a band gap of 1.6 eV. It has been shown to be efficient as a photoluminescent material in nanocrystals.

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3-(Chloromethyl)-4-methoxybenzaldehyde is a natural product that can be extracted from the rhizomes of the plant. It has been shown to have antibacterial activity in laboratory experiments and has been used in traditional medicine for the treatment of fungus infections. 3-(Chloromethyl)-4-methoxybenzaldehyde is an imidazolylmethyl derivative with a hexane structure. It reacts with hydrochloric acid to form a molecule called chloromethylation, which is also known as an esterification reaction. Piperazine acts as a catalyst in this reaction, increasing its scalability and making it suitable for large-scale production. The compound exhibits radical scavenging activity, which may be due to its ability to donate electrons or hydrogen atoms to free radicals.

<p>Dimethylbenzyl chloride is an aromatic hydrocarbon that is used as a precursor to other chemicals and pharmaceuticals. This compound is synthesized by the chlorination of benzene in the presence of a catalyst, such as aluminum chloride or phosphorus pentachloride. The reaction proceeds via a chain reaction mechanism, with the addition of hydrogen chloride as a reactant. The activation energy for this process is around 35 kcal/mol. Dimethylbenzyl chloride can be reacted with polymeric compounds to create telechelic polymers. These polymers are often used in applications where moisture sensitivity is not an issue, such as paints and varnishes.</p>

2,3,7,8-Tetrachloro-p-dioxin (2,3,7,8-TCDD) is a model system for the study of chemical carcinogenesis. It is an environmental pollutant that has been shown to cause liver lesions in both experimental animals and humans. 2,3,7,8-TCDD has been shown to cause maternal blood enzyme activities and fetal malformations in animals. This molecule is also a potent inducer of autoimmune diseases in animal models. There are many analytical methods available for the measurement of 2,3,7,8-TCDD in biological samples. Biological properties of this substance include mitochondrial membrane potential disruption and hepatic steatosis induction. In addition to its toxicological effects on the liver and immune system, 2,3,7,8-TCDD has been shown to be potent hepatocarcinogens in mice and rats.

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<p>12-Amino-1-dodecanoic acid methyl ester hydrochloride salt (12ADM) has been shown to have immunomodulatory properties. It has a nanomolar range of activity, which is the optimal for an immunosuppressant. 12ADM inhibits the transcriptional activity of human immunodeficiency virus type 1 (HIV-1) and HIV-2, as well as other retroviruses, through interactions with specific RNA sequences in the viral genome. The amide group in this compound is essential for its antiviral activity, and it also interacts with betulinic acid to enhance its cytotoxicity.</p>

3-Bromo-1H-1,2,4-triazole belongs to the group of annular azoles. It has been found in the form of two tautomers: 1H-1,2,4-triazole and 2H-1,2,4-triazole. 3-Bromo-1H-1,2,4-triazole has been synthesized at low temperatures (below -30°C) as a result of coordination with bromine atoms. This triazole has also been analysed using x ray diffraction and vibrational spectroscopy. The chemical analyses have shown that 3-bromo 1H-1,2,4 triazole is not stable at high temperatures and decomposes into a mixture of the two tautomers. Tautomeric analysis showed that the 1H form is more stable than the 2H form.

<p>2-Fluoro-4-hydroxybenzaldehyde is an oxidative compound that is a model compound of phenolic compounds. It can be used to synthesize 2,6-dichloroquinone and 2,5,7,8-tetrachlorodibenzo[p]fluoranthene. The metabolic pathway for this compound starts with the oxidative decarboxylation of L-tyrosine to form 4-hydroxyphenylpyruvic acid. This compound is then oxidized by cytochrome P450 enzymes to form 4-(2'-oxo)phenol. The 4-(2'-oxo)phenol can be methylated by S-adenosylmethionine in order to form 2-fluoro-4-hydroxybenzaldehyde.</p>

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<p>2,5-Dichloro-4-methoxybenzoic acid is a synthetic herbicide that inhibits the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). This enzyme is necessary for the synthesis of aromatic amino acids. 2,5-Dichloro-4-methoxybenzoic acid is used as a selective herbicide in plants grown in vitro to eliminate weeds. It is also used to control populations of wild plants and grasses. 2,5-Dichloro-4-methoxybenzoic acid has been shown to inhibit the growth of glyphosate resistant weed species by inhibiting EPSPS activity.</p>

NG,NG'-Dimethyl-L-arginine dihydrochloride is a substrate for nitrite reductase and is used to diagnose kidney disease. It has been shown in vitro to inhibit the activity of steroidogenic enzymes in the zona fasciculata of the adrenal gland. NG,NG'-Dimethyl-L-arginine dihydrochloride is also used as a diagnostic agent in pediatric patients with hypogonadotropic hypogonadism and during inhalation therapy in adults with asthma. NG,NG'-Dimethyl-L-arginine dihydrochloride has been shown to reduce inflammatory diseases such as rheumatoid arthritis and Crohn's disease by inhibiting arginine methylation. The drug also reduces age-related changes in steroidogenesis and blood pressure.