Bioquímicos e reagentes

<p>Stability Moisture Sensitive<br>Applications A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.<br>References Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009), Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009), Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009),<br></p>

<p>Stability Moisture Sensitive: Desiccate<br>Applications A heterobifunctional sulfhydryl cross-linking reagent.<br></p>

<p>Stability Hydrogscopic<br>Applications Defines the P blood-group system and it functions as specific ligands towards receptors of uropathogenic E. coli and the Shigella dysenteriae toxin.<br>References Race, R.R., et al.: Bood Groups in Man, 6th Edn., Blackwell, Osford, 1975, Kallenius G., et al.: FEMS Lett., 7, 297 (1983)<br></p>

<p>Applications Glycyl-L-Tyrosine Dihydrate is used in process for producing N-Glycyltyrosine. Glycyl-L-Tyrosine Dihydrate is the anhydrous form of Glycyl-L-tyrosine(G720108); which is used in preparation method of high quality Aspartame and Aspartame crystallization-inducing agent.<br>References Mimura, T., et al.: Eur. Pat. Appl., (1999); Gao, Z., et al.: Faming Zhuanli Shenqing, (2019);<br></p>

<p>Applications N1,N3-Bis(2-ethylhexyl)-2-methyl-1,2,3-propanetriamine is a hydrolysis product usually found in preparations of the antimicrobial drug hexetidine.<br>References Mende, P.; Food and Chem. Tox. 31(1), 53-58 (1993)<br></p>

<p>Applications 4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.<br>References Phillips, R. et al.: Am. J. Physiol., 152, 523 (1948);<br></p>

<p>Applications Afloqualone acts as a muscle relaxant in humans and may be used in the treatment of muscle spasms affecting rheumatoid arthritis.<br>References Farkas, S. et al.: J. Pharm. Toxicol. Meth., 52, 264 (2005); Yun, H. et al.: Talanta, 73, 635 (2007);<br></p>

<p>Applications Hepes<br></p>

<p>Applications 2-Ethyl-3,6-dimethylpyrazine is a flavour-active and non-volatile compound identified in thermally treated yeast extracts. It is also useful in the synthesis of new flavour additive species of pyrazines.<br>References Alim, A., et al.: J. Sci. Food Agric., 98, 3774 (2018); Lai, M., et al.: J. Therm. Anal. Calorim., 128, 1627 (2017)<br></p>

<p>Applications Dodecanedinitrile (cas# 4543-66-2) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Betahistine Methanesulfonate (cas# 54856-23-4) is a useful research chemical.<br></p>

<p>Impurity Glimepiride EP Impurity B/ USP Glimepiride Related Compound B<br>Applications 4-[2-[(3-Ethyl-4-methyl-2-oxo-3-pyrrolin-1-yl)carboxamido]ethyl]benzenesulfonamide (Glimepiride EP Impurity B) is an intermediate for the preparation of Glimepiride.<br></p>

<p>Stability Hygroscopic<br>Applications Sodium 2-Methyl-4,5-dihydro-1,3-thiazole-4-carboxylate (CAS# 15058-19-2) is a useful reagent for preparing thiazoline and oxazoline substrates for FMN-containing oxidase domains of epothilone synthetase and bleomycin synthetase.<br>References Schneider, T. L., et al.: Biochemistry, 42, 9722 (2003)<br></p>

<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig PYD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig PYD. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Pig PYD, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Pig PYD in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Applications 6-Aminoisoquinoline is a reactant used in the preparation of N-[{2-(4-methylpiperidin-1-yl)-6-(trifluoromethyl)-pyridin-3-yl}methyl] N'-(6,6-fused heterocyclic) ureas as highly potent TRPV1 antagonists.<br>References Sun, W., et. al.: Bioorg. Med. Chem. Lett., 25, 803 (2015)<br></p>