Bioquímicos e reagentes

<p>BDA-366 is a molecule that has potent antitumor activity. It induces apoptosis in cancer cells by dephosphorylating the BCL-2 gene, which leads to the release of pro-apoptotic protein, such as BAX, and the activation of caspases. In addition, BDA-366 has been shown to inhibit proliferation of hematopoietic cells and induce lymphocytic leukemia cell death. Novartis has developed an antibody against BDA-366 to counteract its effects.</p>

<p>Midkine is a protein that belongs to the group of proteoglycans. It is expressed in many tissues, and its function is unknown. Midkine has been shown to have ion channel activity, and it may be involved in receptor binding and ligand-receptor interactions. It may also play a role in cell growth and differentiation due to its ability to activate various cells types. The midkine 1-59 peptide, which corresponds to amino acids 1-59 of the midkine protein sequence, can be used as an inhibitor of this protein. This antibody can also be used as a research tool for investigating protein interactions or studying the effects of peptides on proteins.</p>

<p>Des-Asp1-[Ile8]-Angiotensin II is a peptide that has been shown to have analgesic effects. It has been reported to be active in anesthetized, Sprague-Dawley rats and in primary cultures of rat brain neurons. The peptide binds to the angiotensin II type 1 receptor (AT1) subtype and enhances the activity of the receptor when it is bound by angiotensin II. Des-Asp1-[Ile8]-Angiotensin II also inhibits aminopeptidase activity, leading to an increase in the concentration of angiotensin II. This leads to increased antinociception at high concentrations, which may be due to its effect on baroreceptors or mesenteric blood vessels.</p>

<p>Fluorosalan is a topical antiseptic, which is a fluorinated salicylamide derivative with bacteriostatic properties. This product is synthesized through the halogenation of salicylamide, a compound known for its antimicrobial effects. The incorporation of fluorine enhances the chemical stability and increases its effectiveness against a broad spectrum of pathogenic microorganisms.<br><br>The mode of action of Fluorosalan involves the disruption of microbial cell membranes and inhibition of essential enzyme systems within the pathogen, thus preventing their replication and survival. Its efficacy is attributed to its ability to interfere with microbial metabolism and cellular integrity effectively.<br><br>Fluorosalan is predominantly employed in clinical settings for the treatment of superficial skin infections and as a preventive measure in surgical procedures to reduce infection rates. The application is typically through topical formulations, enabling direct delivery to the site of infection and minimizing systemic side effects. Due to its potent antibacterial properties and low incidence of resistance, Fluorosalan remains a critical component in infection control protocols.</p>

<p>Ac-Val-Asp-Val-Ala-Asp-AMC is a research tool used to study the function of ion channels. It is an activator that binds to the receptor site on ATP sensitive potassium channels. Ac-Val-Asp-Val-Ala-Asp-AMC has been shown to inhibit calcium and sodium ion flux through ion channels, as well as high purity and good solubility. This peptide is useful for studying protein interactions, pharmacology, and life science research.</p>

<p>Ubrogepant is a small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, derived from medicinal chemistry research focused on migraine pathophysiology. It functions by selectively binding to the CGRP receptor, thereby blocking the action of CGRP, a neuropeptide implicated in the pathogenesis of migraines. This mechanism disrupts neurogenic inflammation and vasodilation, processes known to contribute to migraine attacks.</p>

<p>Inhibitor of PCAF bromodomain</p>

<p>Anti Somatostatin (Human, Rat) Serum is a research tool that can be used to activate or suppress the function of cells by binding to their receptors. This antibody binds to somatostatin receptors and blocks their ability to bind to the ligand. It is also used for the detection of ion channels in cell biology. Antibody against somatostatin can be used as an inhibitor in pharmacological studies.</p>

<p>Inhibitor of O-GlcNAcase</p>

<p>WRG-28 is a molecule that inhibits the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). WRG-28 has been shown to inhibit tumor growth and induce tumor regression in vivo. The mechanism of action for WRG-28 is not fully understood, but it may be due to its ability to inhibit the activity of EGFR and other molecules involved in cancer cell proliferation. WRG-28 also has a high affinity for extracellular matrix proteins such as collagen, which may play an important role in inhibiting tumor progression.</p>

<p>Tiodazosin is a pharmaceutical dosage form of Tiodazosin that is a polymeric matrix. It is used to treat hypertension and benign prostatic hyperplasia. Tiodazosin has been shown to increase renal blood flow by inhibiting the activity of α1-acid glycoprotein, which in turn increases the synthesis and release of nitric oxide from vascular endothelial cells. This drug also has been shown to have antihypertensive effects by blocking receptor activity at adrenoreceptors, thereby decreasing the production of catecholamines at sympathetic nerve endings. Tiodazosin is metabolized in the liver by fatty acid oxidation, with subsequent degradation by fatty alcohols and α1-acid glycoprotein. The process can be monitored using a chromatographic method on human plasma.</p>

<p>ML604086 is a molecule with the potential to treat infectious diseases, such as sclerosis. It has been repurposed from its original purpose of being a chemokine receptor antagonist. The molecule binds to chemokine receptors and prevents the binding of chemokines, which are important in immune system function. ML604086 may have the potential to prevent autoimmune disorders by preventing the binding of chemokines that are responsible for the recruitment of inflammatory cells. Strategies for achieving this drug include using ligands that bind only to one receptor or using ligands that are dispensable because they do not affect other aspects of immune system function.</p>

<p>Facade-TEG is a pharmaceutical drug that binds to the cannabinoid type 2 (CB2) receptor. This receptor is found in the immune system and brain. The binding of Facade-TEG to the CB2 receptor inhibits chemokine production, which is an inflammatory mediator. Functional assays have shown that this drug has no effect on other receptors, such as CB1 and G protein-coupled receptors.</p>

<p>The enzyme is a glycohydrolase that catalyzes the hydrolysis of gamma-glutamyl peptide bonds. It is a member of the family of enzymes that catalyze the hydrolysis of peptide bonds in proteins, polypeptides, and oligopeptides. The enzyme has been purified from Escherichia coli and characterized by chromatographic techniques and molecular mass determination. The gene encoding this protein has been cloned into prokaryotic expression vectors or eukaryotic expression vectors for use in protein studies or other investigations.</p>

<p>Please enquire for more information about Quinaprilat-d5 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Nociceptin is an endogenous opioid peptide that has been shown to have a number of effects on the central nervous system. It is found in the central nervous system and peripheral tissues. Nociceptin interacts with the opioid receptors, but it does not activate them. It has been shown to enhance the activity of naloxone, a chemical that reverses the effects of opioids.</p>

<p>MW-150 is a monoclonal antibody that binds to the heavy chains of myasthenia gravis autoantibodies. It prevents the binding of these autoantibodies with muscle cells, which inhibits their effect on neuromuscular transmission. MW-150 has also been shown to have an inhibitory effect on intracellular signalling pathways in nerve cells, inhibiting neurotransmitter release and blocking calcium influx into the cell. The drug is injected intramuscularly or intravenously and can be used for long periods of time without any significant side effects. MW-150 has been tested in humans and found to be safe and well tolerated.</p>

<p>MK6-83 is a synthetic molecule that has been shown to have antimicrobial activity. It inhibits the function of cation channels, which are membrane proteins that form pores in the cell membrane and regulate ion flow. MK6-83 also inhibits autophagy, a process by which cells clear out damaged or unnecessary components. In animal models, MK6-83 has been shown to inhibit tumor growth and prolong survival. The mechanism of action for this drug is not yet well understood but may involve reactive chlorine atoms or non-selective cations.</p>

<p>HS 38 is a prodrug that is metabolized in the body to produce a selective cytotoxic agent known as HS-189. This drug candidate has been shown to have a high degree of selectivity for cancer cells, but not healthy cells. It has also been shown to minimize the side effects of chemotherapy and improve responsiveness to the treatment. HS 38 has shown efficacy in animal models of chronic pain and brain infarction, as well as in cell culture. This drug candidate can be used systemically or postoperatively to maximize efficacy and minimize toxicity.</p>

<p>GSK334429 hydrochloride is a selective corticotropin-releasing factor 1 (CRF1) receptor antagonist, which is a synthetic compound developed by GlaxoSmithKline. As a small-molecule antagonist, it acts by binding to the CRF1 receptor, thereby inhibiting the action of corticotropin-releasing factor (CRF). This interruption in CRF signaling is significant as CRF is a key regulator in the body’s response to stress, influencing both endocrine and behavioral reactions.</p>

<p>Serotonin (5-HT1D) receptor antagonist</p>

<p>Nutlin is a synthetic compound that inhibits the activity of the Mcl-1 protein, which helps to regulate apoptosis. It has been shown to induce apoptosis in HL-60 cells and induce significant cytotoxicity in cancer cells. In transfection experiments, Nutlin inhibited the polymerase chain reaction (PCR) amplification of wild-type dna and induced a greater degree of apoptosis when used with a mutant form of dna. Nutlin also showed minimal toxicity in experimental models.</p>

<p>RP 001 hydrochloride is a serotonin reuptake inhibitor that stabilizes blood pressure by inhibiting the s1p receptor. It also inhibits the reuptake of serotonin, which is an important neurotransmitter in the central nervous system. RP 001 hydrochloride has antioxidant effects and may be beneficial for people with high blood pressure, heart disease, or depression. This drug can be used to stabilize vascular function and prevent thrombosis by inhibiting platelet aggregation. It has been shown to have protective effects against vascular sclerosis and also increases the production of hyaluronic acid, which is a natural glycosaminoglycan found in synovial fluid.</p>

<p>14:0-14:0-d27 Pc is a peptide that belongs to the group of activator peptides. It has been shown to act as an ion channel inhibitor in rat dorsal root ganglion neurons and to inhibit protein interactions in vitro. 14:0-14:0-d27 Pc also has the ability to act as an antibacterial agent and a ligand for the GABA receptor. 14:0-14:0-d27 Pc is soluble in water, making it useful for use in cell biology and pharmacology experiments.</p>

<p>Ml 120b dihydrochloride (Ml120b) is a small molecule drug that can be used to treat non-alcoholic steatohepatitis. Ml120b inhibits the nuclear factor kappa B (NF-κB) pathway by binding and inhibiting the IκB kinase, which is an enzyme involved in NF-κB activation. Ml120b also has other effects on the liver, such as modulating enzymes involved in lipid metabolism and inflammatory damage. Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in hepatocytes, inflammation and damage to the liver cells. NAFLD can lead to nonalcoholic steatohepatitis, a more serious form of the disease with inflammation and damage to the liver cells. Diagnostic methods for NAFLD include ultrasound, CT scan and MRI, but these are expensive and not always accurate. As a result, tissue biopsies may be used to diagnose</p>

<p>Particle size: 130 µmcapacity: 0.2 - 0.3 mmol/g</p>

<p>4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid is a research tool for the study of ion channels, ligands, and receptors. It is a potent inhibitor of potassium channels. The ligand has been shown to interact with the α1A subunit of the nicotinic acetylcholine receptor in an agonistic manner. In addition, 4-[(3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl)amino]-N-(1H-indol-3yl)benzoic acid has been shown to be an antagonist of voltage gated sodium channels.</p>

<p>WAY 208466 dihydrochloride is a drug that has been shown to have antidepressant-like properties and is structurally related to the 5-HT7 receptor agonist, SB-269970. WAY 208466 dihydrochloride antagonizes serotonergic receptors, which are located in the brain, and has been shown to have antidepressant-like activity in animal models of chronic pain. It has also been found to have a profile of efficacy in animal models of depression that is similar to the profile of efficacy seen with 5-HT7 receptor agonists such as SB-269970.</p>

<p>BNP Human is a peptide with a molecular weight of 5.5 kDa. It is the human form of brain natriuretic peptide (BNP) and is used for research purposes in cell biology, immunology, pharmacology, and life science. BNP Human is an activator of ion channels and inhibits protein interactions. BNP Human has been shown to have effects on receptors and ligands. It has CAS number: 60714-06-2.</p>

<p>1,2-Dipentadecanoyl-sn-glycero-3-phosphoethanolamine is a research chemical that has shown potential in various fields. It has been found to have depressive effects on the central nervous system and may be useful in studying the mechanisms of depression. Additionally, it has been shown to interact with taurine channels, which are involved in the regulation of neurotransmitters.</p>

<p>This Neuroendocrine Regulatory Peptide- 2 (human) product can be used as an endogenous suppressor of vasopressin release and is available as a 0.1mg vial. The neuroendocrine regulatory peptide-2 (NERP2) is derived from VGF and it colocalizes with vasopressin in the hypothalamus and it has been found that NERPs prevent vasopressin release from the hypothalamus. Thus NERP2 is involved in body fluid homeostasis through modulating the release of vasopressin.</p>

<p>Inhibitor of PDE2A enzyme</p>

<p>NSC109555 is a small molecule that is chemically synthesized. It has been shown to inhibit the uptake of sodium citrate by mitochondria, which inhibits cellular energy production. NSC109555 also has anti-cancer properties and may be used as a diagnostic agent for cancer. It is activated when it binds to DNA as a template and prevents the formation of dna strands, which prevents the replication of cells. NSC109555 can also cross cell membranes and enter into cells, where it prevents repair mechanisms such as DNA repair from occurring. The chemical structure of this drug is not yet known, but its mechanism of action may involve the response pathway in cancer cells that regulates cell cycle progression, gene expression, and apoptosis.</p>

<p>Lissamine Rhodamine B Sulfonamide-dPEG®4-Acid is a PEG compound containing a rhodamine used for tagging biomolecules, and serving as fluorescent probe for bioimaging applications.</p>

<p>Antibody which blocks the CD95 death receptor which have the ability to elicit apoptosis.</p>

<p>Isoleucyl-Seryl-Bradykinin is a peptide that activates the bradykinin receptor, which is involved in pain sensation and inflammation. This compound is a potent inhibitor of ion channels and also interacts with protein receptors. Isoleucyl-Seryl-Bradykinin has been used as a research tool for studying the function of bradykinin receptors, as well as for pharmacological studies. The CAS number for this product is 86030-63-9.</p>

<p>A synthetic snake toxin peptide sourced from the Green Mamba, Dendroaspis angusticeps. It is an agonist for Muscarinic Acetylcholine Receptor-1 (M1) and has disulfide bonds between Cys3-Cys24, Cys17-Cys42, Cys46-Cys58, and Cys59-Cys64. This product is available as a 0.1mg vial.</p>

<p>AT 1001 is a drug that has been demonstrated to be effective in the treatment of bowel disease. It is specifically designed to bind to acetylcholine receptors on the cell membrane, thereby blocking the action of acetylcholine and reducing inflammation. AT 1001 has been shown to be effective in animal models of autoimmune diseases, such as multiple sclerosis and inflammatory bowel disease. This drug has also been shown to have some effect on otoacoustic emissions and locomotor activity in animals. The binding site for this drug is known, but its exact mechanism of action is not yet clear.</p>

<p>LR3 IGF1 Human is a cytokine that is a member of the interleukin family. It is one of the two forms of human insulin-like growth factor 1 (IGF-1), which plays an important role in regulating cell growth and differentiation. LR3 IGF1 Human has been shown to stimulate the proliferation of various cells, such as lymphocytes and fibroblasts, in vitro. In addition, this cytokine has been shown to inhibit apoptosis induced by serum deprivation.</p>

<p>Roscovitine is a ligand that binds to voltage-gated potassium channels. It has been shown to inhibit the function of these channels, which are involved in the regulation of neuronal excitability and muscle contraction. Roscovitine is used as a research tool in pharmacology and cell biology, and can be used as a high purity reagent for antibody production.</p>

<p>NSC 81178 is a sulfur-containing chemical that was found to be capable of inducing mutations in the DNA of Neurospora crassa. The mutant strain of N. crassa, which responded positively to NSC 81178, had a reduced capacity for conversion of 5-formyluracil to 5-hydroxymethyluracil and showed a decreased level of glutarate synthesis. This suggests that NSC 81178 may be capable of inducing mutations by chemically reacting with DNA and altering its structure. <br>In addition, the KM values for pyrimidines were significantly higher in the mutant strain than in the wild type strain, indicating that NSC 81178 has an effect on nucleotide synthesis.</p>

<p>VCH-759 is a nucleoside analog that is a potential treatment for chronic hepatitis C. VCH-759 inhibits the NS5B polymerase of the hepatitis C virus, an enzyme responsible for viral replication. It binds to the active site of NS5B and prevents it from functioning. VCH-759 has shown antiviral effects in cell culture and animal models and has a safety profile comparable to other nucleoside analogs. The drug also appears to be effective against other types of viruses, including HIV, influenza A, and herpes simplex virus type 2. VCH-759 may be used as a single agent or in combination with other antivirals to treat patients with chronic viral infections.</p>

<p>Clemastanin B is a natural product that belongs to the group of antiviral agents. It has been shown to inhibit the replication of avian influenza, syncytial influenza, and herpes simplex virus. Clemastanin B has also been shown to have an inhibitory effect on the growth of human liver cancer cells in vitro. The antiviral activity against these viruses may be due to its ability to inhibit protein synthesis and cell division.<br>Clemastanin B has been used in traditional Chinese medicine preparations for a number of conditions such as infectious diseases and pharmaceutical dosage.br&gt;<br>The LC-MS/MS method was used for identification and quantification of Clemastanin B from samples taken from the stomachs of cows with diarrhea.</p>

<p>PE859 is a small molecule that inhibits the activity of the enzyme beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). It has been shown to reduce plaque formation and ameliorate symptoms in an Alzheimer's disease mouse model. PE859 also has antiviral properties, which have been demonstrated using a cell culture system and microscopy studies. The mechanism of action for its antiviral properties is not known, but may be related to its ability to inhibit BACE1 activity.</p>

<p>This Scyllatoxin product is a synthetic scorpion (Leiurus quinquestriatus hebraeus) toxin with disulfide bonds between Cys3-Cys21, Cys8-Cys26, and Cys12-Cys28. It can be used as a small conductance Ca2+-activated K+ channel blocker and may assist in pharmacology receptor studies. This product is available as a 0.1mg vial.</p>

<p>Hydroxy chlorodenafil is a metabolite of tadalafil. It is a chromatographic standard that can be used to validate analytical methods for the quantification of sildenafil in pharmaceutical preparations and medicinal preparations. The sample is dissolved in ammonium formate, which is then diluted with acetonitrile and injected into the LC-MS/MS system. A calibration curve is generated using standards of known concentration and the area under the curve (AUC) for each standard is determined by comparing it to the corresponding peak areas of the analyte.</p>

<p>Tetracycline hydrate is a protein synthesis inhibitor that is commonly used to treat urinary tract infections and various types of cancer. It acts as an analog for the natural aminoacyl-tRNA molecule, which binds to the ribosome during protein synthesis. Tetracycline hydrate has been shown to have anticancer properties in Chinese hamster ovary cells by inducing apoptosis and inhibiting tumor growth. This drug also inhibits kinases, such as indirubin, which are involved in cell cycle regulation and proliferation. Tetracycline hydrate has potential as a therapeutic agent for cancer treatment due to its ability to target cancer cells selectively while sparing normal cells.</p>

<p>CD23 antibody (biotin) was raised in rat using CD23 low affinity IgE Fc receptor as the immunogen.</p>

<p>U 75875 is a research tool that belongs to the group of ligands and activators. It binds to a receptor and activates it. U 75875 has been shown to be an inhibitor that is able to block ion channels. It may also be used in cancer therapy, as it can inhibit the growth of cancer cells by binding to the receptor tyrosine kinase.</p>

<p>Vitamin D receptor (VDR) agonist; anti-proliferative in breast &amp; prostate cancer</p>

<p>4-Hydroxy-α-(((3-(2-methoxyphenyl)-1,1-dimethylpropyl)amino)methyl)benzenemethanol is a synthetic compound classified as a beta-adrenergic agonist. This chemical is derived from laboratory synthesis, involving the modification of phenylethanolamine structures to achieve specific adrenergic properties.</p>

<p>ML095 hydrochloride is a phosphatase inhibitor that has shown anti-tumour activity in vitro and in vivo. It inhibits the enzyme placental alkaline phosphatase (PLAP) by binding to it, thereby preventing the removal of phosphate groups from substrates. This leads to an accumulation of substrate molecules, which may have an effect on cell signalling pathways and biological functions such as cell proliferation and migration. ML095 hydrochloride has been shown to modulate cancer cell growth in vitro and in vivo. This molecule also inhibits the activity of other phosphatases including pancreatic, testicular, and intestinal enzymes.<br>The compound is a potent inhibitor of bladder cancer cell growth in vitro and in vivo, as well as bladder carcinoma cells that express high levels of PLAP. The compound has been shown to be safe for use by children with cancer or those who have undergone surgery for bladder cancer at doses up to 10 mg/kg body weight.</p>

<p>CID-1067700 is a small molecule that is able to inhibit the ubiquitin proteasome system (UPS) and effector proteins. This drug has been shown to be active against wild-type strains of bacteria, such as Mycobacterium tuberculosis. CID-1067700 also inhibits autophagy in mycobacteria, which may be a potential therapeutic target for the treatment of mycobacterial infections. It has been shown to reduce ischemic brain damage in mice and may have therapeutic potential for stroke patients. CID-1067700 binds to the ubiquitin ligase Rsp5 and inhibits its ability to activate transcription factors that regulate cell cycle progression. This inhibition of transcriptional regulation leads to apoptosis, or programmed cell death.</p>

<p>Rocacetrapib is an investigational drug that belongs to the class of cholesteryl ester transfer protein (CETP) inhibitors. It has been shown to have antiviral activity against SARS-CoV and may be useful in the treatment of other viruses, such as HIV and influenza. Rocacetrapib has also been shown to inhibit cell growth and induce apoptosis in human lung cancer cells, which are resistant to cisplatin. This compound also binds to proteinase 3, suggesting a potential use in the treatment of Alzheimer's disease.</p>

<p>Big Endothelin-3 (Human, 22-41 Amide) Antiserum is an antibody that can be used to inhibit the activity of Big Endothelin-3. It is a monoclonal antibody that has been raised against Big Endothelin-3 and is specific to this protein. The antibody recognizes the epitope on the human form of Big Endothelin-3 which is located between amino acids 22 and 41. This antibody can also be used to detect peptides in cell lysates or tissue sections.</p>

<p>CD117 antibody (FITC) was raised in rat using murine CD117/c-Kit as the immunogen.</p>

<p>CD81 antibody (FITC) was raised in hamster using murine epithelial cell line PAM212 as the immunogen.</p>

<p>Epacadostat is an enzyme inhibitor that inhibits the enzyme IDO1, which is involved in the regulation of T-cell lymphomas. Epacadostat also has been shown to inhibit cell lysis in autoimmune diseases and HIV infection. The mechanism of action involves the inhibition of toll-like receptor signaling, which leads to a decrease in inflammatory cytokines and chemokines. Epacadostat has been shown to improve immune function and increase body mass index in mice with cancer by increasing energy metabolism. It also increases locomotor activity in mice.</p>

<p>Haemoglobin (Hb) synthetic allosteric modifier</p>

<p>GNE-6640 is a small molecule that inhibits the ubiquitin-proteasome system. It has been shown to be effective in inhibiting tumor growth and metastasis in animal models, as well as inhibiting cell proliferation. GNE-6640 also targets the molecular pathways involved in carcinogenesis, including DNA replication and repair, protein synthesis, and other cellular processes. GNE-6640 has been shown to act as an inhibitor of acid proteases, which are involved in various cellular processes such as apoptosis and autophagy.</p>

<p>18:0(2R-OH) ceramide is a high purity, Life Science, Pharmacology, Receptor, Ligand, Activator, Research tool. 18:0(2R-OH) ceramide is a research tool that can be used to study the interactions of proteins and peptides with ion channels in cells. 18:0(2R-OH) ceramide has also been shown to inhibit the activation of protein kinase C (PKC) by diacylglycerol (DAG). This inhibitor can be used as a cell biology reagent or for pharmacological purposes.</p>

<p>BRD73954 is a potent inhibitor of the HDAC enzyme. It is a molecule that has been shown to inhibit cancer cells, induce pluripotent stem cells and suppress myeloid-derived suppressor cells. BRD73954 contains a carbonyl group, hydroxyl group and fatty acid chain that are essential for its biological activity. The molecule also has a disulfide bond which stabilizes it and helps in the binding to histones. BRD73954 is an all-trans retinoic acid analog that can be used as an adjuvant for vaccines against cancer.</p>

<p>CD38 antibody (PE) was raised in rat using CD38 as the immunogen.</p>

<p>PG01 is a crystalline cellulose that is used in pharmaceutical preparations. PG01 has been shown to inhibit serine proteases, metalloproteases and other enzymes involved in inflammation. This compound was also found to be stable in acidic conditions at high temperatures. PG01 has been shown to inhibit the activity of surface metalloproteases on the surface of cells, which could be used as an anti-inflammatory treatment for chronic inflammatory diseases such as rheumatoid arthritis. The optimum concentration for PG01 to show its effects is 10 μM. It has been shown to have high values against chemical pesticides and can be used as a carrier material for drugs such as insulin.</p>

<p>CD19 antibody (CY5) was raised in rat using murine CD19-expressing K562 human erythroleukemia cells as the immunogen.</p>

<p>Diflufenican-d3 is a fluorescent molecule that belongs to the class of carotenoids. It has been used in the study of ecosystem function, as well as quantifying chlorophyll fluorescence and photosynthetic efficiency. Diflufenican-d3 can be applied to algal biofilms, which are important in aquatic ecosystems. This carotenoid has also been shown to have an effect on heterotrophic organisms, such as bacteria, by altering their metabolism during stressors.</p>

<p>EX 527 is a peptide substrate that interacts with coenzyme Q10. It has been shown to activate SIRT1, an enzyme that regulates the activity of other proteins and plays an important role in cellular metabolism, leading to improved mitochondrial function, reduced inflammation and oxidative stress, and increased cell survival. When EX 527 was administered to mice, it was found to increase the expression of nicotinic acetylcholine receptor α7 (nAChRα7), which is associated with experimental cancer treatments. In addition, EX 527 has been shown to have therapeutic effects on kidney injury and skin cancer when combined with srt1720 treatment.</p>

<p>(±)-2-Hydroxy-1-methoxyaporphine is a drug that inhibits the uptake of glucose and other sugars by cells, which is mediated by a transporter type. It inhibits the shikimate pathway, an enzyme system that produces aromatic amino acids, in plants. This compound also has an inhibitory effect on the liver, preventing it from metabolizing other drugs. The inhibition of this enzyme system may lead to a decrease in plasma concentrations of some drugs, which can cause drug interactions. (±)-2-Hydroxy-1-methoxyaporphine has been shown to have an insulin-stimulated glucose effect in humans and animals. This compound elutes at 3 minutes on reverse phase HPLC with an acid catalyst.</p>

<p>Camp-am is a progestin contraceptive medication that prevents pregnancy by interfering with the ovulation process. It has been demonstrated to have a damaging effect on the genus Campylobacter, which can cause gastrointestinal illness. This drug is also known to modulate blood glucose levels and tumorigenicity in mice. Camp-am has been shown to activate horse melanocytes and increase hyperactivity in rats. Camp-am also induces glioma in mice, although it does not have any harmful effects on other cells in vitro. Camp-am has been shown to be activated by reperfusion following treatment with hydrogen peroxide or lipid peroxidation inhibitors, but not by a variety of other agents such as light, heat, or oxygen radicals.</p>

<p>Heliotrope B is a film-forming polymer that has been shown to have anticancer properties. It has been used in the treatment of brain tumors, and other cancers such as melanoma and lymphoma, by local administration. Heliotrope B inhibits the growth of cancer cells by binding to their surface membrane receptors. This binding leads to a loss of cell adhesion and prevents tumor cells from attaching to surrounding tissues. Heliotrope B also has antiviral effects against hepatitis viruses, including types A, B, and C. It binds to viral particles and inhibits virus entry into the cell. In addition, heliotrope B can be used in the treatment of HIV infection through its ability to block messenger RNA synthesis by inhibiting reverse transcriptase activity. The polymer is also effective against bacterial strains such as Staphylococcus aureus and Escherichia coli because it disrupts their outer membranes. Heliotrope B has an acidic pH level that makes it</p>

<p>Drotaveraldine is a chromophore, which means it has a fluorescence property. It is used as an excipient in pharmaceutical preparations to improve the appearance of granules and tablets. Drotaveraldine is also used as a pH indicator for citric acid. Drotaveraldine absorbs light at about 350 nm and emits light at about 460 nm when excited with ultraviolet light. The excitation-emission spectrum of drotaveraldine can be used to detect hydrogen chloride, caffeine, or chloride ions in organic solvents. Drotaveraldine is occasionally used for curing biliary calculi in humans, although this use has not been approved by the FDA.</p>

<p>Lamiidoside is a cytotoxic compound found in the ethanol extract of Verbascum thapsus. It has been shown to inhibit the growth of cervical cancer cells, and is a potential treatment for cancer. Lamiidoside is an iridoid glucoside with significant cytotoxicity against tumor cells. It also has antibacterial activity and can be used as a natural food preservative.</p>

<p>HIV-1 TAT Clade-B Recombinant is the recombinant protein that belongs to HIV-1. It is a regulatory protein that binds to the human immunodeficiency virus type 1 (HIV-1) RNA genome and regulates viral replication. HIV-1 TAT Clade-B Recombinant has been shown to be highly infectious and can be used for the study of HIV infection, pathogenesis, and transmission.sequence: MEPVDPRLEP WKHPGSQPKT ACTNCYCKKC CFHCQVCFIT KALGISYGRK KRRQRRRPPQ GSQTHQVSLS KQPTSQSRGD PTGPKE.</p>

<p>Brr2 inhibitor C9 is an antibody that blocks the activation of the Brr2 protein by binding to it. This antibody is a research tool that can be used in cell biology and pharmacology studies, as well as for the study of protein interactions and receptor ligands. The antibody has been shown to increase the amplitude of calcium-dependent currents in cultured rat neurons. It also inhibits voltage-gated potassium channels and enhances GABAergic transmission. This product is high purity, with a purity level of 98%.</p>

<p>CD40 antibody (FITC) was raised in rat using CD40 as the immunogen</p>

<p>Vafidemstat is a tetracycline compound that has been shown to be effective in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. It is able to penetrate the blood-brain barrier and act on the central nervous system. Vafidemstat inhibits hyperactivity by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain, which may be due to its ability to inhibit chloride transport into cells. Vafidemstat also increases GABA concentrations in lymphatic vessels, which may contribute to its anti-inflammatory effects.</p>

<p>LDV is a drug that is used to treat chronic viral hepatitis. It belongs to the class of drugs known as nucleoside analogues and inhibits the replication of the virus by blocking DNA synthesis. LDV has been shown to be effective for treating chronic hepatitis B, chronic hepatitis C, and human immunodeficiency virus (HIV) infection. LDV is metabolized by the liver into its active form, tenofovir. LDV can cause liver impairment and has drug interactions with other drugs. LDV also causes thermal expansion in plastics such as PVC tubing used for dialysis equipment.</p>

<p>CS 2100 is a high-specificity, ethyl-group-containing, blood pressure stabilizer that acts as a serotonin reuptake inhibitor. It has been shown to have efficacy in the treatment of angina and stabilizing cardiac function. CS 2100 has also been used in clinical studies for the treatment of pulmonary embolism, where it was found to reduce the incidence of pulmonary hypertension. CS 2100 binds to serotonin receptors and blocks serotonin reuptake, which enhances its antidepressant effects. CS 2100 also has activity against nt-proBNP (a marker for heart disease) and other markers that are associated with cardiovascular diseases such as sclerosis or coagulation.&gt;&gt;END&gt;&gt;</p>

<p>L-655708 is a benzodiazepine binding inhibitor that binds competitively to the GABA A receptor and blocks the response to GABA. It has been shown to reduce anxiety in mice with a model system of panic disorder. L-655708 has also been shown to have pharmacological activity in mice with brain functions, such as mouse hippocampal, locomotor activity, and receptor binding. L-655708 can be used for treatment of anxiety disorders, such as generalized anxiety disorder (GAD) or panic disorder (PD), and seizures. The drug has a synergistic effect with other drugs that act on GABA receptors, such as benzodiazepines.</p>

<p>MPS is a compound that is used in peptide synthesis. It is a maleimidopropionate reagent that reacts with primary amines to form stable amides. MPS can be used as a building block for the synthesis of polymers, and it contains an N-hydroxysuccinimide ester group that can react with thiols to form stable disulfides. This product is available for purchase from Quanta BioDesign.</p>

<p>Parathyroid Hormone (Human, 69-84) is a peptide hormone that regulates the levels of calcium and phosphate in the blood. It regulates bone formation and remodeling by targeting bone mineralization. Parathyroid hormone binds to to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications and is available has a 0.5mg vial.</p>

<p>3-(5-(3-(Dimethylamino)phenoxy)pyrimidin-2-ylamino)phenol is a synthetic chemical compound that can be used as an antibody to study protein interactions, ion channels, and cell biology. It is a research tool for pharmacology and receptor studies. 3-(5-(3-(Dimethylamino)phenoxy)pyrimidin-2-ylamino)phenol is also used as a ligand in the activation of receptors such as the acetylcholine receptor and the muscarinic acetylcholine receptor. This chemical has been shown to be an inhibitor of potassium channels and calcium channels. CAS No. 956128-01-1</p>

<p>N-Formylloline is a kinase inhibitor analog that has been developed for medicinal use as an anti-tumor agent. It works by inhibiting protein kinases, which are enzymes involved in cell cycle regulation and cancer cell growth. N-Formylloline has shown promising results in inhibiting the proliferation of cancer cells and inducing apoptosis, making it a potential candidate for cancer treatment. This compound has been studied extensively in Chinese hamster ovary cells and human urine samples, where it demonstrated potent inhibition of kinase activity. N-Formylloline is a highly effective inhibitor that may have significant potential as an anticancer agent.</p>

<p>3-(4-(Biphenyl-4-yl)-1H-1,2,3-triazol-1-yl)quinuclidine is a peptide that binds to the receptor site of ion channels. It is an inhibitor of ligand binding and has been shown to be an activator of ion channels. 3-(4-(Biphenyl-4-yl)-1H-1,2,3-triazol-1-yl)quinuclidine is also a cell biology research tool that can be used for the study of protein interactions. This compound has high purity and does not contain any impurities or contaminants. 3-(4-(Biphenyl-4-yl)-1H-1,2,3-triazol-1-yl)quinuclidine is a pharmacological agent that can be used as a diagnostic tool in life sciences research. It is registered under CAS No. 1779540 - 13 - 4 and</p>

<p>Avex-73 is a chemical deterrent, which is derived from naturally occurring plant-based extracts. It operates by affecting the sensory pathways of birds, making treated areas undesirable for them through olfactory and gustatory discomfort. When applied, Avex-73 interacts with the specific chemosensory receptors present in avian species, creating an aversive, yet non-lethal reaction. This makes it an effective tool in managing bird-related challenges in various environments.</p>

<p>CD79b antibody (Azide free) was raised in hamster using the beta chain of the murine B-cell receptor as the immunogen.</p>

<p>Potent inhibitor of the calcium-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM. GK 563 is 22000 times more active against GVIA iPLA2 than against the cytoplasmic phospholipase GVIA cPLA2. In β pancreatic cells from rat, GK 563 was shown to inhibit the β cell apoptosis when co-administered with pro-inflammatory cytokines.</p>

<p>Isodecyl citrate is an inhibitor of kinases, which are enzymes involved in cell signaling and regulation. It is an analog of donepezil, a medication used to treat Alzheimer's disease. Isodecyl citrate has been shown to inhibit the growth of cancer cells in Chinese hamsters and human tumors by inducing apoptosis, or programmed cell death. This compound also inhibits the activity of protein kinases, which are involved in the regulation of cell division and proliferation. Isodecyl citrate has potential as an anticancer agent due to its ability to selectively target cancer cells while sparing healthy cells. Additionally, it can be detected in urine samples, making it a promising biomarker for cancer diagnosis and treatment monitoring.</p>

<p>WAY 267464 dihydrochloride is a selective agonist used in neuroscience research, derived from synthetic sources to specifically target the neuropeptide Y receptor Y1. This compound operates by mimicking the natural ligand's action on the Y1 receptor, leading to specific receptor activation. This mechanism is significant in the modulation of various physiological processes related to neuropeptide Y, including appetite regulation, anxiety, and stress response.</p>

<p>CD107b antibody (Allophycocyanin) was raised in rat using glycoproteins purified from BALB/c mouse embryo 3T3 cell line as the immunogen.</p>

<p>6-[2,5-Bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone is a novel small molecule that has been shown to be a potent and selective activator of the protein kinase C (PKC) family. It binds to the PKC alpha isoform with an IC50 of 0.5 nM and displays low nanomolar activity against PKC beta and gamma isoforms. The activation of PKC alpha by 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]-2(3H)-benzothiazolone leads to increased phosphorylation of proteins involved in cell signaling pathways, including G protein coupled receptors (GPCRs), tyrosine kinases and</p>

<p>CD3e antibody (Spectral Red) was raised in hamster using H-2Kb-specific murine cytotoxic T lymphocyte as the immunogen.</p>

<p>CD45 antibody (FITC) was raised in mouse using chicken CD45 as the immunogen.</p>

<p>CD19 antibody (PE-CY7) was raised in mouse using human CD19 as the immunogen.</p>

<p>Rabbit anti Mouse IgM is a monoclonal antibody that belongs to the category of antibodies. It is specifically designed to target and bind to mouse IgM, making it an essential tool for various research applications in the field of Life Sciences. This antibody can be used for studying the role of IgM in different biological processes such as anti-VEGF (vascular endothelial growth factor) therapy, adiponectin signaling, β-catenin regulation, and more. Additionally, Rabbit anti Mouse IgM can be utilized for detecting specific proteins like human chorionic gonadotropin (hCG), alpha-synuclein, epidermal growth factor (EGF), c-myc, and glycopeptides. Its binding ability allows researchers to explore these proteins' functions and interactions within cellular pathways. Furthermore, this antibody has been shown to induce Fas-mediated apoptosis in certain experimental settings. With its high specificity and versatility, Rabbit anti Mouse IgM is an invaluable tool for advancing scientific</p>

<p>CD62L antibody (Allophycocyanin-CY7) was raised in rat using C3H/eb cloned murine B lymphoma 38C-13 as the immunogen.</p>

<p>CD25 antibody (FITC) was raised in rat using IL-2-dependent BALB/c murine helper T-cell clone HT-2 as the immunogen.</p>

<p>CD106 antibody (Azide free) was raised in rat using murine CD106/VCAM-1 as the immunogen.</p>

<p>CD62E antibody (PE) was raised in mouse using human CD62E/E-selectin as the immunogen.</p>

<p>CD45R antibody (PE-CY7) was raised in rat using abelson murine leukemia virus-induced pre-B tumor cells as the immunogen.</p>