Bioquímicos e reagentes

<p>Calcitonin (salmon) acetate is a peptide hormone that is naturally produced by the parafollicular cells of salmon. It contains a disulphide bridge between two cysteine residues, which is crucial for its biological activity. This hormone plays an important role in regulating calcium levels in the body and is commonly used in life sciences research. Calcitonin (salmon) acetate has been shown to have potent effects on bone metabolism, making it a valuable tool for studying osteoporosis and other bone disorders. Its unique structure and function make it an essential component of biochemical studies and research in the field of endocrinology.</p>

<p>Purified native Human PSA-ACT Complex protein</p>

<p>Peptide aiC15-RIIDLLWRVRRPQKPKFVTVWVR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2 is a synthetic peptide that binds to the 5HT3 receptor. It has been shown to have an effect on locomotor activity and growth factor secretion in wild type mice and cell culture, as well as binding to acetylcholine receptors in C57/BL6 mice. 2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn was synthesized by the reaction of furoic acid with L -alanine, L -glycine, L -arginine and L -ornithine. The product is a white powder.</p>

<p>For-Met-Leu-pNA is a synthetic peptide that can be used as a research tool for studying protein interactions. It has been shown to inhibit ion channels and may be useful in the treatment of epilepsy, especially in cases of drug resistant seizures. For-Met-Leu-pNA is also an inhibitor and can be used as an anticonvulsant.</p>

<p>H-CQSTPLSPPPLTPK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CQSTPLSPPPLTPK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CQSTPLSPPPLTPK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CQSTPLSPPPLTPK-OH at the technical inquiry form on this page</p>

<p>Poly-L-Lysine Hydrobromide is a neurotrophic factor that is used to stimulate nerve growth in the peripheral nervous system. It has been shown to increase the production of nerve growth factor, which is important for neuronal development and regeneration. Poly-L-Lysine Hydrobromide also has biological properties against human erythrocytes, enabling it to bind to the erythrocyte membrane and subsequently cause hemolysis. This process is mediated by Toll-like receptors. The active form of this drug has been shown to have antiviral activity against HIV and other viruses in transfection experiments using cells from mice, as well as an ability to inhibit replication of herpes simplex virus type 1 (HSV-1) in a model system consisting of rat neurons grown on a polymer substrate. Poly-L-Lysine Hydrobromide can be cleaved into smaller pieces by enzymes such as DNase I or terminal transferases, forming polymers</p>

<p>Inhibitor of PDE4 enzyme; anti-inflammatory</p>

<p>Lysozyme antibody was raised in rabbit using full length protein corresponding to amino acids 1-129 of Hen Egg White lysozyme as the immunogen.</p>

<p>FluOrescent Brightener 119 is a fluorescent brightener that is stable in the presence of sulfate and UV light. It can be used to monitor the level of water in a pool by measuring the intensity of the fluorescence. FluOrescent Brightener 119 is soluble and can be used with x-ray films or cyclodextrin to produce a strong fluorescent effect. This chemical has a wavelength at 585 nm, which is visible to the human eye. It also emits light in the blue region at 475 nm, making it an ideal choice for optical brightening agents.</p>

<p>Abz-Gly-Phe(NO2)-Pro-OH is a peptide that has been shown to have antihypertensive activity. It also has radical scavenging properties, and it can be used as an amino acid composition marker. Abz-Gly-Phe(NO2)-Pro-OH has been shown to inhibit the growth of faecalis and subtilis, which are both Gram positive bacteria. The peptide has also been shown to have inhibitory properties against proteolytic enzymes from bovine casein, human serum and rat blood pressure.</p>

<p>Influenza B antibody was raised in mouse using Influenza B as the immunogen.</p>

<p>Dabcyl-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Edans is a bifunctional peptide that inhibits HIV protease. The peptide binds to the active site of the enzyme and blocks access to the catalytic triad, inhibiting its function. This peptide has been shown to inhibit viral life in human cells infected with HIV type 1 (HIV1), as well as virions, which are released into the bloodstream. Dabcyl is a small molecule inhibitor of HIV1 protease that also inhibits cellular proteases. It has been shown to inhibit viral life in human T cell lines (THP1) and other cells infected with HIV type 1 (HIV1).</p>

<p>Plasminogen antibody was raised in sheep using purified mouse plasminogen as the immunogen.</p>

<p>Fmoc-11-Aminoundecanoic Acid is a molecular modeling reagent that interacts with other elements to form Building Blocks. Fmoc-11-Aminoundecanoic Acid has been shown to have cancer interacting properties, elucidating the molecular interactions of peptides and proteins. It has been used in research as an active analog for growth factors. Fmoc-11-Aminoundecanoic Acid interacts with other molecules, including peptides and proteins, by proteolysis to produce new molecules. The chemical structure of this molecule can be altered through reactions with other molecules such as amino acids or nucleotides.</p>

<p>Boc-Val-Leu-Lys-AMC is a research tool that has been shown to activate ion channels and increase the permeability of cell membranes. This compound also binds to receptors on cells, which may be due to its ability to bind with antibodies. Boc-Val-Leu-Lys-AMC has been used as an inhibitor in protein interactions and pharmacology studies, as well as for the study of ion channels in cell biology.</p>

<p>Purified Recombinant HSV1 gG protein</p>

<p>Peptide H-AKTDHGAEIVYKSPVVSGDTSPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-KDWGFKKFI-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KDWGFKKFI-OH is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KDWGFKKFI-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KDWGFKKFI-OH at the technical inquiry form on this page</p>

<p>H-KRSLPALTNIIKILRHDIC-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KRSLPALTNIIKILRHDIC-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KRSLPALTNIIKILRHDIC-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KRSLPALTNIIKILRHDIC-OH at the technical inquiry form on this page</p>

<p>H-KVYALFYKLDIVPLN-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KVYALFYKLDIVPLN-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KVYALFYKLDIVPLN-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KVYALFYKLDIVPLN-OH at the technical inquiry form on this page</p>

<p>H-Ser-Phe-Leu-Leu-Arg-NH2 is a peptide that contains a cyclic backbone with aromatic residues. It has been shown to enhance the release of catecholamines from rat striatal slices and to inhibit platelet activation by thrombin receptor. It is also an agonist at the thrombin receptor and has been found to be effective in inhibiting the proteolytic activity of serine proteases such as thrombin, trypsin, and elastase. This peptide exhibits conformational properties that are favorable for interaction with protein receptors.</p>

<p>COMU reagent is a copper-containing, natural compound that can be used in intrauterine diagnosis. The COMU reagent has been shown to have potent antagonistic activity against the CB2 receptor and hydrogen bond donor site. This product also can be used to detect the presence of peptide hormones, such as LH and FSH, in urine samples. The COMU reagent has been shown to bind to integrin receptors on cells, which are involved in cell adhesion and migration. The conformational properties of this compound allow it to form a complex with cyclic peptides that are found in human liver cells infected with hepatitis C virus (HCV).</p>

<p>Ac-CHAPYRNISQRISVDPVT-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CHAPYRNISQRISVDPVT-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CHAPYRNISQRISVDPVT-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CHAPYRNISQRISVDPVT-NH2 at the technical inquiry form on this page</p>

<p>Inhibitor of PDE4 enzyme; anti-inflammatory</p>

<p>H-Ser-Phe-Leu-Leu-Arg-OH is a cyclic peptide that has been shown to have cytotoxic effects against cells of the atherosclerotic lesion in vivo. It also has antioxidant properties and can be used as a biocompatible polymer for the treatment of autoimmune disease. This drug is not potent enough to be used as an antibacterial agent but is effective against some strains of Mycobacterium tuberculosis and Mycobacterium avium complex. This drug binds to integrin receptors on cells, which may account for its low potency.</p>

<p>H-QVLEQAPEWLNGFVAK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-QVLEQAPEWLNGFVAK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-QVLEQAPEWLNGFVAK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-QVLEQAPEWLNGFVAK-OH at the technical inquiry form on this page</p>

<p>Enzastaurin is a synthetic small molecule inhibitor, which is derived from chemical synthesis with a primary mode of action as an inhibitor of protein kinase C beta (PKCβ). As a potent pathway modulator, it disrupts signal transduction pathways involved in cell proliferation and survival. The inhibition of PKCβ is particularly important as this enzyme is linked to the progression and survival of certain cancer types. Through this mechanism, Enzastaurin impedes the downstream activities that promote tumor growth and angiogenesis.</p>

<p>β-Sheet Breaker Peptide iAß5 (Bulk) is a peptide that inhibits the formation of β-sheets in proteins. It has been shown to be an excellent inhibitor of protein interactions, with good selectivity for its target. This peptide also has high purity and can be used as a research tool for studying the function of ion channels and antibodies.</p>

<p>Peptide H-GAVVGVGDESR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Ser-Phe-Leu-Leu-Arg-Asn-OH is a biocompatible polymer that has been shown to have strong antioxidative properties. This polymer has been used in the development of a new class of drug for the treatment of inflammatory bowel disease, which may be due to its ability to inhibit toll-like receptor activity. H-Ser-Phe-Leu-Leu-Arg-Asn-OH also has potent immunosuppressive and antiinflammatory activities, and is stable at doses up to 200mg/kg. These properties make this polymer an attractive candidate for use as a therapeutic agent in treating bowel disease.</p>

<p>Please enquire for more information about rel-DHMEQ including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-D-Pro-OH is a building block for peptide synthesis. It is a protected form of proline with an amido group, which can be used to synthesize polypeptides. Fmoc-D-Pro-OH can be coupled with other amino acids using the aldol condensation or methodologies like the strategy of organocatalysts. This building block is also useful in the synthesis of macrocycles and cyclohexanones, which are aliphatic and cyclic compounds. The recoverable nature of Fmoc-D-Pro-OH allows it to be reused in multiple reactions, so it is an economical choice for Building Blocks.</p>

<p>As a chemotactic peptide, For-Met-Leu-Phe (FMLP) has chemotactic properties, which means it can attract cells. For example it is a chemoattractant for phagocytic leukocytes and neutrophils. Neutrophils which have seven transmembrane G-protein coupled receptors are activated during the acute inflammatory response by FMLP and other chemotactic factors which bind to its surface receptors. This results in the activate of NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.<br>This product is available as a 0.5mg vial.</p>

<p>Peptide H-R^LITGRLQSL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Influenza A Virus Nucleoprotein Recombinant Monoclonal Antibody is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Influenza A Virus Nucleoprotein Recombinant Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Enterotoxin STp is an Escherichia coli Enterotoxin, with the following disulfide bonds: Cys5 and Cys10; Cys6 and Cys14; Cys9 and Cys17 and available as the trifluoroacetate salt.<br>One-Letter-Code: H-NTFYCCELCCNPACAGCY-OH</p>

<p>6-Azido-Hexanoic Acid is a lysine derivative that is used for Click Chemistry, which involves the use of reactive nitrenes, such as azides, to create stable covalent bonds with other molecules. This product is also used in diagnostic agents and has shown anticancer activity against prostate cancer cells. 6-Azido-Hexanoic Acid can be synthesized using Click Chemistry and x-ray crystal structures have been determined. The structure consists of a cyclic peptide that contains an amide bond between two lysine residues. The compound has a neutral pH and can be detected by gravimetric analysis.</p>

<p>Colivelin is a peptide that can be found in the central nervous system. It has been shown to have a wide variety of biological activities, including being an inhibitor of neuronal death, enhancing axonal growth and proliferation, and decreasing the activity of signal pathways. Colivelin has also been shown to inhibit the proliferation of human osteosarcoma cells by binding to their cell surface receptors.</p>

<p>Peptide H-LGFLHSGTAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>MBHA resin is a solid phase synthesis material that is used as a building block in the synthesis of peptides. The resin is a very stable, insoluble polymer with a high capacity for binding amino acids. MBHA resin provides a clean surface for peptide synthesis and an efficient coupling reaction. It can be used to make any type of peptide, including natural and unnatural amino acids and modified amino acids.</p>

<p>Benidipine is a calcium channel blocker that inhibits the flow of calcium ions into cardiac and smooth muscle cells, which decreases the rate of these cells' contractions. Benidipine also has been shown to have a protective effect on the heart by preventing injury from coronary artery disease and other cardiovascular diseases. In addition, benidipine is not broken down in the liver and has a low risk of drug interactions. Benidipine has been found to be effective in reducing blood pressure in patients with chronic renal failure, although it may cause tubulointerstitial injury. The effects of benidipine are thought to be due to its ability to inhibit the release of growth factor-β1 from human polymorphonuclear leukocytes (PMNLs) and inhibit the proliferation of HL-60 cells.</p>

<p>Fmoc-ß-Ala-OH is a synthetic amino acid that is used in the synthesis of cyclic peptides. It has been shown to have receptor activity, such as the ability to bind to an erythrocyte membrane protein. Fmoc-ß-Ala-OH is also able to stimulate macrophage-like cells and polypeptide synthesis. Fmoc-ß-Ala-OH has been synthesized by chemical ligation, followed by purification on an agarose gel. This synthetic amino acid is used as a building block for affinity ligands, which are compounds that bind to specific receptors or other molecules with high specificity and affinity.</p>

<p>TSH antibody is a monoclonal antibody used in Life Sciences research. It specifically targets and binds to the thyroid-stimulating hormone (TSH) receptor, blocking its interaction with TSH. This antibody can be used in various applications, including immunohistochemistry and ELISA assays, to study the role of TSH in different biological processes.</p>

<p>Linaclotide is a peptide drug that has been shown to be effective in treating chronic constipation. It belongs to the class of pharmacological agents and is used as a treatment for bowel disease, specifically chronic idiopathic constipation. Linaclotide increases the frequency of bowel movements by acting on the ileum and colon. This drug has been shown to be safe for use in pregnant women and children, with no adverse effects observed at doses up to 100 mcg/kg/day. The most common side effect is diarrhea, which can be managed with dietary changes or other medications. Linaclotide has not been found to interact with other drugs, but patients should always consult their doctor before taking any new medication while on linaclotide.</p>

<p>This is a building block for peptide synthesis. It is a protected lysine derivative that can be used in the formation of peptides. This functionalized lysine derivative can be deprotected and reacted with other amino acids to form peptides. The protecting group, Fmoc, protects the lysine from unwanted reactions during the synthesis process. The side chain, Palmitoyl-Glu-OtBu, allows for the attachment of other molecules to the lysine side chain.</p>

<p>CA 15-3 protein is a globulin chemokine that plays a crucial role in various Life Sciences applications. It is commonly used as a target for monoclonal antibody-based assays and research. The CA 15-3 protein contains tyrosine residues that can be phosphorylated, leading to the activation of superoxide production. This protein is also involved in antibody-drug conjugate (ADC) development, where monoclonal antibodies are linked to cytotoxic drugs to specifically target cancer cells expressing CA 15-3 protein. Additionally, CA 15-3 protein has been found to interact with other proteins such as dopamine receptors, nuclear progesterone receptors, and phosphatases, suggesting its involvement in steroid signaling pathways. Furthermore, neutralizing antibodies against CA 15-3 protein have shown potential therapeutic benefits in certain diseases.</p>

<p>H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 is a potent activator of the human growth hormone receptor, which leads to increased levels of insulin growth factor 1 (IGF1). H-His-D-Trp-Ala-Trp-D-Phe-Lys NH2 causes an increase in locomotor activity and somatotrophs. This peptide has been shown to be effective in treating metabolic disorders such as obesity and diabetes mellitus type 2. It also has antiviral properties that may be useful for the treatment of infectious diseases, such as HIV.</p>

<p>Corticosterone-OVA conjugate</p>

<p>Legionella pneumophila antibody was raised in mouse using Legionella pneumophila as the immunogen.</p>