Building Blocks

Applications 2-Methoxycarbonylphenylboronic acid

Applications Methyl Methacrylate-d5 (CAS# 55935-46-1) is a useful isotopically labeled research compound.

Applications 9-Acridinecarboxylic acid is used in the synthesis of short DNA-binding peptides.

Applications 2-ETHYNYLPYRIDINE (cas# 1945-84-2) is a useful research chemical.

Applications The methyl ester of 3,5-Dihydroxybenzoic Acid (D451700) with potential antifeedant activity for pine weevil, Hylobius abietis.
References Sunnerheim, K. et al.: J. Agric. Food Chem., 55, 9365 (2007); Tung, Y.-T. et al.: Biores. Technol., 98, 1120 (2007);

Applications tert-Butyl 2,2,2-trichloroacetimidate is used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wessel, H., et al.: J. Chem. Soc., Perkin Trans. 1, 2251 (1985); Armstrong, A., et al.: Tetrahedron Lett., 29, 2483 (1988)

Applications 3-Pentanone-d10 (CAS# 54927-77-4) is a useful isotopically labeled research compound.

Applications phenyl(pyridin-4-yl)methyl 4-methyl-2-(pyrimidin-2-yl)-1,3-thiazole-5-carboxylate (cas# 1281055-79-5) is a useful research chemical.

Applications 5-Chloroisoquinoline (cas# 5430-45-5) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Methyl Methoxyacetate is a reagent used in the synthesis of diphenylamine-terepthalaldehyde resins which maybe be used as a catalyst for tetrahydropyranylation.
References Tanemura, K. et al.: Org. Prep. Proc. Int., 48, 72 (2016); By: Robiette, R. et al.: J. Am. Chem. Soc., 138, 737 (2016);

Applications 5,12-Dihydroquinoxalino[2,3-b]quinoxaline is an inhibitor of NADPH oxidase 1 (NOX1).
References Gianni, Davide., et at.: ACS Chem. Biol., 5, 9(2010);.

Applications (±)-2-Ethylhexanoic-d15 Acid (CAS# 352431-38-0) is a useful isotopically labeled research compound.

Applications syn-2-Pyridinealdoxime is a 2-substituted pyridine derivative with inhibitory activity against prolyl-4-hydroxylase. syn-2-Pyridinealdoxime is used in the preparation of DNA-binding silver nitrate complexes. syn-2-Pyridinealdoximeis the N-demethylated analogue of AChE inhibitor Pralidoxime (P701120).
References Dowell, R.I. et al.: Eur. J. Med. Chem., 28, 513 (1993); Hoskovcova, M. et al.: Neuroendorinol. Lett., 30, 152 (2009); Abu-Youssef, M.A.M.: Inorg. Chem., 49, 9788 (2010);

Applications N-Methyl-d3-form-d1-amide (CAS# 110505-55-0) is a useful isotopically labeled research compound.

Applications 2-Bromo-4'-methoxyacetophenone is a α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.
References Taylor, W., et al.: Bioorg. Med. Chem., 4, 1515 (1996), Elchelby, M., et al.: Science, 283, 1544 (1999), Shen, K., et al.: J. Biol. Chem., 276, 47311 (2001), Wang, P., et al.: Biochemistry, 41, 6202 (2002),

Applications Heterocyclic compound used in cosmetic compositions.
References Windheuser, J., et al.: J. Pharm. Sci., 71, 121 (1982), Davis, E., et al.: J. Med. Entomol., 22, 237 (1985), Osimitz, T., et al.: J. Toxicol., 35, 435 (1997), Ross, E., et al.: Drug Metab. Dispos., 32, 783 (2004),

Applications (E)-1-Phenyl-1-butene was used to study olefin oxidation by cytochrome P-450. It can be used to synthesize nonracemic allylic amines. It can also be used to prepare aryl oxiranes by direct epoxidation.
References Liebler, D., et al.: Biochem., 22, 5482 (1983); Liang, C., et al.: J. Am. Chem. Soc., 130, 343 (2008); Imuta, M., et al.: J. Org. Chem., 44, 1351 (1979)

Applications m-Cresol-d8 (CAS# 302911-90-6) is a useful isotopically labeled research compound.

Applications 7-Hydroxyquinoline (cas# 580-20-1) is a useful research chemical.

Applications 5-Bromofuran-2-carboxaldehyde used in the preparation of isoindolinones from furfural. Also used in the preparation of brominated nitrovinylfuran which displays antibacterial activity.
References Caillot, G. et al.: New. J. Chem,, 37, 1195 (2013); Scholz, T. et al.: Bioorg. Med. Chem. Lett., 21, 795 (2013);

Stability Light Sensitive
Applications 4-(1-Naphthylvinyl)pyridine (cas# 16375-56-7) is a useful research chemical.

Applications Carbon(isothiocyanatidic)acid Ethyl Ester (cas# 16182-04-0) is a compound useful in organic synthesis.

Applications Indaconitine is used in preparation of aconine and pseudaconine, their NMR spectra, and effect of solvents on conformation as reactant/reagent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Deng, H.Y., et al.: Nat. Prod. Commun. 9, 785-786 (2014)

Applications 1,3,5-Triphenylbenzene-d18 (CAS# 34496-33-8) is a useful isotopically labeled research compound.

Applications 3-Chloro-6-methylpyridazine is used for preparation of heterocyclic compounds as integrase inhibiting antiviral agents.
References Betail, G., et al.: Ann. Pharm. Fr., 36, 317 (1978), Elben, U., et al.: J. Chem. Res., 316 (1978),

Applications 2-Bromo-4’-fluoroacetophenone is an intermediate in the synthetic preparation of competitive inhibitors of aromatase.
References Utsukihara, T., et al.: J. Molec. Cata. B: Enzymatics., 45, 68 (2007); Vinh, T.K., et al.: Bioorg. Med. Chem. Lett., 9, 2105 (1999);

Applications Maleimide (cas# 541-59-3) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1,4-Dimethoxybenzene-d10 (CAS# 74079-00-8) is a useful isotopically labeled research compound.

Applications 2-Chloroisonicotinic Acid is a derivative of Isonicotinic Acid (I821760) and is used as a reagent in the synthesis of (phenylmorpholinyl)pyrimidinones as selective and orally active glycogen synthase kinase-3β inhibitors.
References Fukunaga, K., et al.: Bioorg. Med. Chem. Lett., 23, 6933 (2013)

Applications 2-Bromo-4'-fluoroacetophenone-2',3',5',6'-d4 (CAS# 1219803-30-1) is a useful isotopically labeled research compound.

Applications trans-2-Hexenal is an unsaturated aldehyde that has an apple odour. trans-2-Hexenal is produced by soybean plants, and is also a sex pheromone produced by the female polyphemus moth.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Corbo, M., et al.: J. Agr. Food Chem., 48, 2401 (2000); De Lucca, A., et al.: J. Food Sci., 76, M381 (2011); Riddiford, L.: Science, 158, 139 (1967)

Applications 2-Methyl-3-oxopentanoic Acid Methyl Ester is an intermediate in the synthesis of antiproliferative polyketide (+)-R-aureothin.
References Werneburg, M., et al.: Chem. Bio. Chem., 9, 2064 (2008);

Applications Pyridine-2-carbonyl chloride hydrochloride is used in the synthetic preparation of various pharmaceutical goods. Pyridine-2-carbonyl chloride hydrochloride is also used for the synthesis of active esters of isonicotinic (I821760) and picolinic acids (P437220).
References Christensen, J.B., et al.: Molecules., 6, 47 (2001); Fuerstner, A., et al.: Tetrahedron, 51, 773 (1995);

Applications N-(2-hydroxyethyl)benzamide (cas# 18838-10-3) is a useful research chemical.

Applications o-Hydroxy-α,α-dimethylbenzyl Alcohol is an intermediate in the synthesis of 2,4’-Bisphenol A (B519490), an derivative used for the preparation of low-molecular-weight epoxy resins.
References Steinmetz, R., et al.: Trends Endocrinol. Metab., 9, 124 (1998), Petersen, H., et al.: Eur. Food Res. Technol., 216, 355 (2003),

Applications 4'-Dimethylaminophenyl acetylene

Stability Hygroscopic
Applications 3-(Dimethylamino)propionic Acid Hydrochloride is a useful reagent for the preparation of biological active small molecules.
References Salado, I. G., et al.: J. Med. Chem., 57, 2755 (2014)

Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.

Applications 4,4-Dimethoxy-2-butanone is a reactant in the synthesis of naphthalimide-naphthyridine derivatives as a fluorescent probe for the detection of hydroxyl radicals in living cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meng, L., et. al.: Chem. Commun., 50, 4843 (2014)

Applications Ethyl-2,2,2-d3-triphenylphosphonium Bromide (CAS# 1560-55-0) is a useful isotopically labeled research compound.

Applications 1,2-Dimethylcyclohexane is used in the preparation of rhodium nanoparticles as recyclable catalysts.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stratton, S.A., et. al.: Catalysis Today, 183, 96 (2012)

Applications Isopropenylboronic Acid Pinacol Ester, can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes.
References Salaun, J. et al.: Topics in Curr. Chem. 1, 144 (1988); Chen, J. et al.: J. Amer. Chem. Soci., 135, 5316 (2013);

Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.
References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)

Applications 4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer.
References Lewis, E. A., et al.: J. Nat. Prod., 66, 62 (2003)

Applications Tetra-n-propyl-d28-ammonium Bromide (CAS# 284474-84-6) is a useful isotopically labeled research compound.

Applications 4-Hydroxychlorpropham is an intermediate in synthesizing 4-Hydroxychlorpropham Sulfate Sodium Salt (H825075), which is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.
References EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004);

Applications Ethyl-d5 Methanesulfonate (CAS# 1219795-44-4) is a useful isotopically labeled research compound.

Applications 4-Bromo-2-fluorobenzoic Acid is a halogenated derivative of benzoic acid. 4-Bromo-2-fluorobenzoic Acid is used in the synthesis of pharmaceutically significant products such as d-Amino acid oxidase inhibitors.
References Katane, M., et al.: J. Med. Chem., 56, 1894 (2013); Vasbinder, M.M., et al.: J. Med. Chem., 56, 1996 (2013);

Applications 1-Piperidine-d10-carbonyl Chloride (CAS# 1219803-31-2) is a useful isotopically labeled research compound.

Applications 2-(Dimethylamino)ethanethiol Hydrochloride is a starting material for the synthesis of Echothiophate Iodide (E325800). Echothiophate Iodide is an anticholinesterase drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ashani, Y., et al.: Biochem. Pharm., 30, 2593 (1981)

Applications 2-sulfanylpropan-1-ol (cas# 3001-64-7) is a useful research chemical.

Applications 1-Butane-d9-sulfonyl Chloride (CAS# 1219794-70-3) is a useful isotopically labeled research compound.

Applications o-Nitrofluorobenzene is an intermediate in the synthetic preparations of various pharmaceutical goods.
References Ma. W., et al.: QSAR. Combin. Sci., 25, 895 (2006); Sutton, P.G., et al.: Analyst., 124, 877 (1999); Yi, W.B., et al.: J. Fluorine. Chem., 129, 524 (2008);

Applications 4-tert-Butyl-d9-catechol-3,5,6-d3 is a useful isotopically labeled compound of 4-tert-Butylcatechol (B810793)

Applications 4-n-Butylphenol-2,3,5,6-d4,OD (CAS# 1219795-04-6) is a useful isotopically labeled research compound.

Applications p-Tolyl-d7 Isocyanate (CAS# 1219798-59-0) is a useful isotopically labeled research compound.

Applications methyl 2-hydroxy-4-methylpentanoate (cas# 40348-72-9) is a useful research chemical.

Applications p-Xylene-d4 (ring-d4) (CAS# 16034-43-8) is a useful isotopically labeled research compound.

Applications 4-Bromo-1-butyl Acetate is a useful synthetic intermediate. It was used in the synthesis of 9-alkylguanine derivative. It can also be used to prepare potent heat shock protein 90 inhibitors.
References Kjellberg, J., et al.: Tetrahedron Lett. 27, 877 (1986); Zhang, L., et al.: J. Med. Chem., 49, 5352 (2006)

Applications BIX 01294 is a euchromatic histone-lysine N-methyltransferase 2 (EHMT2) inhibitor, induces autophagy and apoptosis in human neuroblastoma cells, specifically human bladder cancer cells.
References Cui, J. et al.: Cancer Cell Int., 15, 1 (2015); Shin, J. et al.: Biochem. Biophys. Res. Comm., 350, 428 (2015);

Applications 2-Chloroanisole-d3 (methyl-d3) (CAS# 1398065-46-7) is a useful isotopically labeled research compound.

Applications A thiozole derivative that is converted to L-cysteine by the enzyme 2-amino-Δ2-thiazoline-4-carboxylic acid hydrolase (ATCase) upon induction by S-compounds in certain bacteria.
References Tamura, Y. et al.: J. Gen. Appl. Microbiol., 47, 193 (2001); Shiba, T. et al.: J. Gen. Appl. Microbiol., 68, 2179 (2002);

Applications Propiolamide (cas# 7341-96-0) is a compound useful in organic synthesis.

Applications Z-2-Fluoro-3-(3-pyridyl)acrylic Acid (cas# 359435-42-0) is a compound useful in organic synthesis.

Applications N-Boc-3-aminopropanol is used in the synthesis of Fagomine (F101055), an inhibitor of α-​glucosidase and β-​galactosidase and to prepare 5-​substituted isoquinoline derivatives.
References Yokoyama, H., et al.: Tetrahedron Asymmetry, 18, 852 (2007); Yamada, R., et al.: PCT Int. Appl., WO 2004009555 A1, 20040129 (2004)