Building Blocks

<p>Applications 9-cis-Retinyl Stearate-d5, is the labeled analogue of 9-cis-Retinyl Stearate (R275600), a fatty acid ester of Retinol isomer, found mainly in the retina.<br>References Bridges, C.D.B., et al.: Methods Enzymol., 81, 463 (1982),<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate (cas# 41468-25-1) is a useful research chemical.<br></p>

<p>Applications A chelating agent, forming complexes with most metal ions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References El-Didamony, A., et al.: Drug Test. Anal., 2, 122 (2010), Chan, A., et al.: J. Med. Chem., 53, 3086 (2010), Ehrman, T., et al.: Bioorg. Med. Chem., 18, 2204 (2010),<br></p>

<p>Applications 2-Aminoethyl Diphenylborinate is a transient receptor potential (TRP) activator for TRPV1, TRPV2, and TRPV3 (1). 2-Aminoethyl Diphenylborinate inhibits TRPC6 and TRPM8. 2-Aminoethyl Diphenylborinate may potentially be used as a therapeutic agent for pain management and treatment for diseases caused by hypersensitivity and temperature misregulation.<br>References (1) Hu, H.Z., et. al.: J. Biol. Chem., 279, 35741 (2004)<br></p>

<p>Applications The phosphonate Diethylenetriaminepenta(methylenephosphonic acid) is a wastewater pollutant, and a component of phosphorous-containing nanoparticles and materials, such as in the preparation of chitosan nanoparticles for plutonium pulmonary decorporation.<br>References Rott, E.; et al.: Water Res., 145, 608 (2018); Leost, L.; et al.: J. Chem. Soc., Dalton Trans., 47, 11605 (2018).<br></p>

<p>Applications Diglycolic Acid is a known metabolite of Diethylene Glycol(D444285) and acts as a nephrotoxic agent in human proximal renal tubule cells. It is also used in the synthesis of N-interlinked imipramines which show apoptotic activity against malignant cells as well as signs of combatting Burkitt’s lymphoma.<br>References Landry, G. et al.: Toxicol. Sci., 124, 35 (2011); Besenhofer, L. et al.: Toxicol. Sci., 123, 374 (2011); Bright, S. et al.: Bioorg. Med. Chem. Lett., 23, 1220 (2013);<br></p>

<p>Applications Derivative of monoenoic and trienoic analogs of Sorbic Acid with antifungal activity.<br>References Guerin, J. et al.: Annales Pharmaceutiques Francaises 44, 373 (1987)<br></p>

<p>Applications A product from thermal and hydrolytic degradation of Orlistat. Orlistat impurity.<br>References Stalder, H., et al.: Helv. Chimica Acta, 75, 1593 (1992),<br></p>

<p>Applications N,N-Dimethylthioformamide<br></p>

<p>Applications 1,3-Diethynylbenzene (cas# 1785-61-1) is a useful research chemical.<br></p>

<p>Applications 4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.<br>References Miller, M., et al.: Nat. Methods, 6, 439 (2009); Seth, P., et al.: J. Med. Chem., 53, 8309 (2010); Cui, H., et al.: Eur. J. Med. Chem., 45, 5140 (2010);<br></p>

<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>

<p>Applications (E)-Ethyl 4-Bromo-3-methyl-2-butenoate (cas# 51318-62-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(2-Aminoethyl)glycine (cas# 24123-14-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Sulfamoylbenzoic Acid is used as a reagent in the synthesis of carbonic anhydrase inhibitors anticonvulsant agents.<br>References Singh, S. et al.: J. Enz. Inhib. Med. Chem., 31, 417 (2016);<br></p>

<p>Applications 3-Hydroxy-O-methyl-L-tyrosine Hydrochloride is used in the preparation of tyrosine-based components of natural products such as saframycin MX1 and its analogs, which are naturally potent anti-tumor agents currently under clinical development.<br>References Schmidt, E.W.; et al.: Tetrahedron Lett, 45, 3921 (2004); Nelson, J.T.; et al.: AEM, 73, 3575 (2007)<br></p>