Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Ethyl (E)-cinnamate is a cinnamic acid derivative that belongs to the class of phenylpropenoids. It has been shown to have biological properties, such as enzyme activities and antioxidative properties. Ethyl (E)-cinnamate has also been shown to be a potent photosynthetic activator in vitro. This compound can be used as a precursor for the synthesis of cinnamic acid, which is important in the metabolism of energy production and locomotor activity.</p>

<p>2-Chloro-4-methylphenyl-N-(2-chloro-4-methylphenyl)-4,5-dihydroimidazol-2amine is a potent immunosuppressive drug. It has been shown to be effective in the treatment of autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. The drug has been found to be safe and effective in animal models of cardiac disease. 2C4MPI is an analog of azathioprine, which is used for the treatment of inflammatory and autoimmune diseases. In addition, this drug has been shown to have antihyperglycemic properties by inhibiting glucose production in the liver and increasing insulin sensitivity in muscle tissue. 2C4MPI also reduces collagen synthesis, which may be useful in treating inflammatory diseases that are caused by excess collagen deposition such as skin conditions like psoriasis or acne vulgaris.</p>

<p>4,6-Dichloroquinoline is a macrocyclic compound that has been found by accident. It inhibits the growth of malaria parasites by binding to the enzyme heme oxygenase. The inhibition of this enzyme leads to an accumulation of toxic products derived from the heme molecule and causes cell death. 4,6-Dichloroquinoline is also fluorescent and can be used as a reagent for cross-coupling reactions or as an antimalarial drug. The compound fluoresces when it binds to metal cations such as chloride and ligands such as chloride ions. This property can be used in the detection of these species in solution or in solid samples.</p>

<p>2-(Prop-2-en-1-yl)oxane is a tetrahydrofuranyl compound that is used in organic synthesis as an allylation agent. It is also used in the functionalization of ethers, multicomponent reactions, derivatization reactions, and many other chemical syntheses. 2-(Prop-2-en-1-yl)oxane is typically used as an anhydride or ester catalyst. It has been shown to catalyze the reaction between ethyl acetate and propylene oxide.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-2,2-dimethylpentanenitrile is a nonpolar solvent that can be used as a phase transfer catalyst and reagent for the synthesis of cyclopentanone derivatives. It is also used as a hydrolyzing agent for the synthesis of 1-bromo-3-chloropropane. 5-Chloro-2,2-dimethylpentanenitrile can be used to synthesize cyclic ketones from alkyl halides and 1,1'-oxydiacetonitrile with an acetone or isobutyronitrile as a catalyst.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Furan-2-yl)-2,2-dimethylpropan-1-one is a catalytic reagent that is used in the synthesis of furan derivatives. 1-(Furan-2-yl)-2,2-dimethylpropan-1-one can be produced from 2,5-dihydrofuran with carbon tetrachloride and PCl5 or by reacting 2,5-dihydrofuran with CCl4. This product reacts as a dipole and has been shown to have some experimental and theoretical uses in catalysis. It is also a reactant in the production of acetophenone and pyridine. The abundances of this product are determined by the constants A = 3.14159 × 10−8 m²/s², B = 4π × 10−7 m³/s¹, C = 1.6180 × 10−3 m/s and D</p>

<p>2-Chloro-1-(2-chlorophenyl)ethanone is an antiarrhythmic drug that belongs to the group of methyl ketones. It is used to treat asthma and bronchitis. 2-Chloro-1-(2-chlorophenyl)ethanone is a chiral compound with two possible enantiomers. The rotation of the molecule can be altered by changing the solvent. The dihedral angle between two hydrogen bonds in this molecule can also be changed, which affects the way that it interacts with bronchial receptors. This compound has been shown to have antiarrhythmic properties, as well as being able to inhibit transfer hydrogenation reactions in cyclohexane.</p>

<p>4-Iodo-m-xylene is an organic solvent that is used as a precursor in the synthesis of medicines. It is a member of the methyl group with hydrogen, chlorine and other elements. 4-Iodo-m-xylene has been shown to be activated by both hydrochloric acid and hydrogen peroxide, which leads to the formation of methylbenzenes. The chlorides are then added to form enolate anions, which can be protonated by hydrogen chloride to form ligands. These ligands can react with peroxide to produce biomolecules such as proteins or nucleic acids.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Propionylbenzoic acid (4PB) is a racemic mixture of the two enantiomers, 4-propionyloxybenzoic acid and 4-hydroxybenzoic acid. It is an ester formed from terephthalic or isophthalic acids and a propionic acid. The ester group in 4PB reacts with alcohols to form esters, diesters, and condensation products. This compound acts as a muscle relaxant by blocking the action of calcium ions in nerve cells. Its active form can be formed by enzymatic oxidation from its inactive form, 4-hydroxybenzoic acid.</p>

<p>4-Phenylpiperidin-4-yl)methanol (PPI) is a compound that inhibits motility and can be used as an analgesic. It is a white solid with a molecular weight of 174.2 g/mol. PPI is soluble in organic solvents such as acetone, ethyl acetate, and chloroform. The most common side effects are dizziness, drowsiness, and headache. These side effects may be due to the piperidine substituent in the molecule or because it can cause an increase in blood pressure and heart rate.</p>

<p>4,4-Dimethoxybutanoic Acid Methyl Ester is a synthetic compound that can be synthesized by ring-opening of the iminium salt. The stereoselective synthesis of this compound has been achieved through the use of a chiral auxiliary. This compound has shown biological properties in some studies, such as inhibition of glutamic and threonine amide synthesis. 4,4-Dimethoxybutanoic Acid Methyl Ester also has the potential to be used in natural product synthesis.</p>

<p>1-(4-Methylpiperazin-1-yl)propan-2-ol is a piperazine derivative that acts as an analgesic. It is structurally related to the morpholine and piperazine class of drugs, with the addition of a methyl group in the para position on the phenyl ring. This addition may alter the binding site for 5-HT receptors and other sites that are involved in migraines. 1-(4-Methylpiperazin-1-yl)propan-2-ol has shown no anti-migraine effects in experimental studies, but it does have antimigraine effects when given to rats. It also has been shown to interact with indolylalkylamines and halogens.</p>

<p>6-Iodohexanoic acid is a chemical compound that belongs to the group of 6-hydroxyhexanoic acid fatty acids. It is synthesized by reacting the corresponding nitro compound with an acceptor such as 6-hydroxyhexanoic acid. The synthetic route for 6-iodohexanoic acid includes the use of phenyliodine diacetate and nitric acid. 6-Iodohexanoic acid has been shown to have activity against pests such as lepidoptera, which are insects that include butterflies and moths.<br>6-Iodohexanoic acid is also known to be an important histone deacetylase inhibitor. This inhibitor suppresses cancer cell growth and proliferation, which may be due to its ability to inhibit the activity of enzymes involved in the synthesis of prostaglandins.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-8-methylquinoline is a chlorinated aromatic compound that has antioxidant properties. It inhibits monoamine oxidase activity and has been shown to have an inhibitory effect on clomipramine, which is a type of antidepressant. 2-Chloro-8-methylquinoline has also been shown to have neurotoxic effects in vitro and can cause the death of neurons by inhibiting their growth. The mechanism of this inhibition is not yet clear, but it may involve the inhibition of amine uptake or the inhibition of amine synthesis. 2-Chloro-8-methylquinoline has also been shown to be effective in vivo and can cause an increase in locomotor activity in rats.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Benzyl-1H-imidazole is an imidazole derivative that is synthetically produced. It has been shown to inhibit β-glucosidase, which may be a byproduct of cancer cells. 4-Benzyl-1H-imidazole also inhibits the activity of the h3 receptor, which is found in human neutrophils and T cells. 4-Benzyl-1H-imidazole has antibacterial activity against gram positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae, but not against gram negative bacteria such as Escherichia coli or Pseudomonas aeruginosa.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methoxypropanoyl chloride is a pharmaceutical drug that has been used to treat restenosis. It is also used in the preparation of pharmaceuticals, and as a modifier for receptors. 3-Methoxypropanoyl chloride can be taken up by cells and may be converted to other compounds through oxidation or reduction reactions. 3-Methoxypropanoyl chloride has been shown to have anticancer activity at low energy levels. This compound has also been shown to decrease inflammation in animal models of inflammatory diseases. 3-Methoxypropanoyl chloride may act as an affinity ligand when coupled with amide, which can potentiate its antagonist effects on receptor activity in vitro.</p>

<p>Versatile small molecule scaffold</p>

<p>Heptyl carbamate is a cholinergic antagonist of the blood disorders. It has been shown to inhibit hydroxy and hiv infection. In vitro assays have shown that heptyl carbamate inhibits the synthesis of fatty acid, thereby reducing cholesterol levels and inhibiting the production of insulin resistance in cells. Heptyl carbamate also binds to the same site on acetylcholinesterase as donepezil, which blocks the breakdown of acetylcholine and leads to an accumulation of this neurotransmitter in nerve cells. This increased concentration of acetylcholine in nerve cells can lead to a reduced incidence of Alzheimer's disease-related symptoms.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzoylpiperidin-2-one is a cyclic amide that contains an iminium group. It is synthesized in the presence of phenolic and yields two isomers, with one being more stable than the other. 1-Benzoylpiperidin-2-one has been shown to inhibit nicotine metabolism by inhibiting cytochrome P450 enzymes. Mechanistically, 1-benzoylpiperidin-2-one binds to the heme moiety at the active site of the enzyme and acts as a reversible inhibitor. The nitrogen atom of 1-benzoylpiperidin-2-one binds to the methylene carbon of heme b, leading to inhibition of microsomal enzymes such as phenol hydroxylase and deuterium incorporation into piperidine metabolites.</p>

<p>1-(4-Benzyloxy)phenyl-2-bromoethanone is a carbonylation agent that is used to synthesize alkaloids. This compound is efficient and can be used in the synthesis of rigidin, a tetrasubstituted benzene. It is also used as a reagent for the protection of benzyl groups. The deprotection reaction occurs by using triphosgene or catalytic hydrogenation.</p>

<p>1-Phenylpent-4-en-2-amine is a fatty alcohol that is soluble in water and organic solvents. It is used as a pharmaceutical dosage form, usually as an ester or salt. 1-Phenylpent-4-en-2-amine has been shown to be effective for the treatment of high blood pressure and diagnosing serotonin transporter gene disorders. The human body metabolizes this drug into conjugates, which are then excreted from the body. Diagnostic agents can be used to detect the presence of these metabolites in urine samples.</p>

<p>2-Hydroxy-4-phenylbutanoic acid is an aliphatic hydrocarbon that is used for the synthesis of chiral compounds. It inhibits enzymes such as esterases, transferases, and oxidoreductases. 2-Hydroxy-4-phenylbutanoic acid also catalyzes the Friedel-Crafts reaction. This chemical has been shown to be a stereoselective enzyme inhibitor, which may be useful in asymmetric synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Ethenesulfonyl)ethan-1-ol is a versatile compound with various characteristics and applications. It has high bioavailability and can be easily absorbed by the body. This compound is known to inhibit the activity of glucoamylase, an enzyme that breaks down carbohydrates. It has also been studied for its potential antiviral properties. In addition to its pharmaceutical applications, 2-(Ethenesulfonyl)ethan-1-ol finds use in other industries as well. It is commonly used in research chemicals and synthetic cannabinoids production. Its phototoxicity properties make it useful in the development of sunscreen products. Moreover, it can be utilized as a building block in the synthesis of copolymers, glutamate derivatives, fatty acids, and other organic compounds. Overall, 2-(Ethenesulfonyl)ethan-1-ol is a valuable compound with diverse applications across multiple industries. Its unique characteristics make it an essential ingredient</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Diphenylpropan-2-amine is a molecule with a hydrophobic nature. It has been shown to activate the enzyme monoamine oxidase in the brain, leading to an increase in the production of heat and causing hyperthermia. 1,3-Diphenylpropan-2-amine is metabolized by isozymes in different tissues and organs. 1,3-Diphenylpropan-2-amine interacts with pethidine (meperidine) to produce meperidine analogues, which are active at opioid receptors. These meperidine analogues have been shown to cause respiratory depression and hypotension when administered intravenously. The benzyl groups on this molecule have also been shown to interact with imidazoles such as ketoconazole and clotrimazole.</p>

<p>Cycloheptanecarbaldehyde is a divalent hydrocarbon that is an agonist at the opioid receptor. It also has been shown to react with chlorinated compounds, such as hydrochloric acid or chloramine, which may indicate its presence in the environment. Cycloheptanecarbaldehyde has been found to be reactive with amines and other compounds that have a hydrogen atom attached to a heteroatom such as oxygen or nitrogen. The compound can also react with aliphatic hydrocarbons under certain conditions, thereby forming tropylium ions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Furan-2,3-dicarboxylic acid is a fluorogenic probe that reacts with water vapor to form a fluorescent product. The reaction of furan-2,3-dicarboxylic acid with methanol and ethylene glycol yields 2,5-furandicarboxylic acid. This compound is also the product of the reaction of furan-2,3-dicarboxylic acid with magnesium salt in anhydrous sodium carbonate. Furan-2,3-dicarboxylic acid can be oxidized by pyridinium chlorochromate (PCC) to form 5-hydroxymethylfurfural. Furan-2,3-dicarboxylic acid has been shown to react with p-hydroxybenzoic acid in the presence of an oxidation catalyst to yield a furandicarboxyl derivative.</p>

<p>4-(Methoxycarbonyl)furan-3-carboxylic acid is a fluorescent compound that can be used as an efficient hydrogenation reagent. It is also a versatile and efficient synthetic intermediate for the synthesis of bicyclic and heterocycled amines. 4-(Methoxycarbonyl)furan-3-carboxylic acid is generated from the reduction of 4-(methoxycarbonyl)pyrazole with lithium aluminum hydride, followed by hydrolysis. This method has been shown to yield high yields and functionalized products.</p>

<p>Versatile small molecule scaffold</p>

<p>6-(Hydroxymethyl)-2-methylpyridin-3-ol is a resonance stabilized compound with a proton magnetic resonance and a pyridine ring that is sterically hindered. It reacts with hydroxymethylation to form 6-(hydroxymethyl)pyridin-3-ol, which can be used as a precursor for other compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>This drug is a potent inhibitor of the glutamate receptor. It binds to the glutamate receptor and blocks the binding of glutamate, which is an excitatory neurotransmitter in the central nervous system. Ethyl 2-amino-4-methyl-5-phenylthiophene-3-carboxylate can be used as an antagonist to inhibit glutamate activity, thereby preventing neuronal death in patients with Parkinson's disease and Alzheimer's disease. This drug also has an antagonistic effect on leukocyte elastase, which is a protein that breaks down connective tissue and cartilage. The synthesizing of pyrimidines is inhibited by this drug. It also inhibits receptors for glutamate, specifically N-methyl D-aspartate (NMDA) receptors. This drug blocks the binding of NMDA to its receptor site, preventing ion channels from opening so neurons cannot fire or release neurotransmitters.</p>

<p>Versatile small molecule scaffold</p>

<p>N-Tosyl-L-aspartic acid is a chemical compound that is used as an intermediate in the manufacture of other compounds. It can be obtained by reacting tosyl chloride with L-aspartic acid. The azide group reacts readily with amines, alcohols, and carboxylic acids. This reaction forms the corresponding ester or amide of the carboxylic acid. N-Tosyl-L-aspartic acid has also been used in the synthesis of penicillins, cephalosporins, and thiocarbamates. N-Tosyl-L-aspartic acid is synthesised by refluxing a mixture of thionyl chloride and aspartic acid in dextrose solution containing amines such as triethylamine or pyridine.</p>

<p>2-{[(Furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid is a water soluble drug that is used as a dietary supplement. It has been shown to be effective in inhibiting the growth of cancer cells and preventing the carcinogenic properties of some chemical compounds. 2-{[(Furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid has been shown to inhibit the growth of cancer cells, with no evidence of toxicity in rats. The compound was found to be safe for use in humans, but its carcinogenic activity could not be ruled out. Studies have shown that 2-[(furan-2-yl)methyl]amino]-5-(sulfamoyl)benzoic acid can inhibit the growth of cancer cells and prevent the carcinogenic properties of chemical compounds. 2-[(furan-2-yl)methyl]am</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,1,2-Triethoxyethane is a solvent with a high boiling point and low volatility. It is used as a reagent in organic chemistry and as an intermediate in the production of pharmaceuticals such as erythromycin. 1,1,2-Triethoxyethane is relatively non-reactive to other chemical compounds because it does not undergo elimination reactions or acidic reactions easily. The compound has been shown to be capable of selectively reacting with levulinate at the C3 position with nitro groups at the C5 position. This selective reaction can lead to erythromycin derivatives.</p>

<p>5,6-Dimethoxyisobenzofuran-1,3-dione is a hydrolysis product of the organophosphates paraoxon and parathion. It is used as an acetylcholinesterase inhibitor in high-throughput screening for drug discovery. The inhibition of acetylcholinesterase by 5,6-dimethoxyisobenzofuran-1,3-dione leads to a build up of acetylcholine in the synapse and increased transmission of nerve impulses. This reaction can be monitored using a fluorometric assay with an electron transfer probe that detects fluorescence intensity. Fluorometric assays are also used to monitor the activity of butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). These enzymes are found in blood plasma and have been used as biomarkers for exposure to organophosphates.5,6-</p>

<p>Tetrahydrophenazine is a mixture of isomers that contains 1,2,3,4-tetrahydrophenazine and 2,3,4-trihydroxyphenazine. It has a variety of uses in animals to treat respiratory diseases and as an anti-inflammatory agent. Tetrahydrophenazine acts by inhibiting the production of hydrogen peroxide in the respiratory system and by preventing the release of histamine from mast cells. Tetrahydrophenazine also has the potential to be used as an antiviral agent or for treatment of skin diseases. In addition to its use as an antibiotic, tetrahydrophenazine may have additional therapeutic applications due to its ability to inhibit calcium uptake in cells and act as an antioxidant.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Ethylpyridin-1-ium-1-olate is an alkali metal salt of 2-ethylpyridine. It has a residue of chlorine and n-oxide, which are used as intermediates in the synthesis of dyes and pharmaceuticals. 2-Ethylpyridin-1-ium-1-olate is also used as a reagent for the preparation of pyridine derivatives and thioamides. This compound reacts with ammonia to form isonicotinic acid, which can be used as an intermediate for the synthesis of fungicides.</p>

<p>1,1,3,3-Tetramethyl-2,3-dihydro-1H-indene (TMTD) is a stilbene derivative that has been shown to be a potent reducing agent. TMTD is used in the synthesis of pharmaceutical preparations. It is also found as a byproduct of the endogenous synthesis of indole and other aromatic compounds. The reduction products of TMTD are toxic and have been shown to cause cardiovascular diseases at high concentrations. TMTD can also be used as an acceptor in metallocene reactions because it has a high electron affinity for metal complexes.</p>

<p>2-Chloroallyl phenyl sulfide is a hydroxide, or an organic compound with the formula ClCH=CClOS. It is a colorless to yellowish liquid that is soluble in water and alcohol. 2-Chloroallyl phenyl sulfide is used as a reagent in organic chemistry for the conversion of hydroxy groups into their disulfides, which are useful as reducing agents. 2-Chloroallyl phenyl sulfide can be prepared by reacting chloral with benzene and sodium hydroxide. It has been found to inhibit the growth of bacteria including Pseudomonas aeruginosa, Escherichia coli, Bacillus subtilis, Staphylococcus aureus, Streptococcus faecalis, and Klebsiella pneumoniae.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Trifluoromethanesulfonylphenyl)hydrazine is a neutral, styryl dye that has two distinct spectral bands: one bathochromic and the other hypsochromic. It is an alkaline substance that can be dissolved in water. 4-Trifluoromethanesulfonylphenyl)hydrazine is synthesized from the indoles or by substituting a hydrazine group for the hydroxy group of an indole derivative. This agent is also used to synthesize merocyanine dyes, which have a carbocyanine as the central chromophore. Merocyanine dyes are often used as fluorescent labels for nucleic acids because they emit light at wavelengths longer than those emitted by conventional fluorescein dyes. The benzindocyanines are merocyanines with substituents on the quinone moiety that include phenyl, nitro, or car</p>

<p>Diethylsulfamide is a drug that inhibits the activity of tropomyosin, an important protein in the regulation of muscle contraction. It binds to the amino acid residues on the surface of tropomyosin and prevents its interaction with actin, which is a major component of muscle cells. This leads to relaxation of muscles and relief from pain caused by osteoarthritis. Diethylsulfamide has also been shown to have anti-inflammatory properties due to its ability to reduce prostaglandin synthesis.</p>

<p>3-(Thiophen-2-yl)prop-2-ynoic acid is an initiator for the oxidation of organic substances. It can undergo oxidation to form reactive intermediates that react with other molecules to produce new substances. This reaction is catalyzed by copper, which oxidizes 3-(thiophen-2-yl)prop-2-ynoic acid in a two step process. The first step involves formation of a peroxide intermediate, which reacts with a second molecule of 3-(thiophen-2-yl)prop-2-ynoic acid to form an alkenyl radical. The alkenyl radical reacts with another molecule of 3-(thiophen-2-yl)prop-2-ynoic acid to generate a 2,3,5,6 tetraene compound. The mechanism for this reaction is not well understood but it has been shown that it occurs in nature and is important in biomolecular chemistry.</p>

<p>1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-one (DPP) is a base that has antibacterial properties. It is used as the starting material for the synthesis of pharmaceutical preparations containing isothiocyanates. These are compounds that are used in the treatment of cancer and other diseases. DPP can also be used to analyze molecular structures by measuring the distance between atoms and calculating the molecule's centroid (center point). DPP may have anticancer activity due to its ability to induce apoptosis.</p>

<p>Versatile small molecule scaffold</p>

<p>N-Methylpyridine-3-sulfonamide (NMP) is a drug that is used in the treatment of hepatitis C. It inhibits the activity of viral RNA polymerase and has been shown to be effective against many different types of viruses, such as HIV, hepatitis B virus, and hepatitis D virus. NMP also has a strong affinity for salicylic acid and can be used to remove this compound from plasma samples. The use of NMP in experiments with human serum or plasma samples showed that it has low toxicity. NMP binds to proteins with high affinity in the presence of acetonitrile and dissolved sildenafil. Reconstituted human liver microsomes were used to determine its mechanism of action on the metabolism of drugs such as acetaminophen and erythromycin. A liquid chromatography method was developed for the determination of NMP in plasma samples using reverse-phase high-performance liquid chromatography (RP-HPLC</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Benzodioxole-5-carboxamide is a synthetic drug that has been shown to have antinociceptive and hypotensive properties. It is structurally related to longum and anisidine, two natural products with known pharmacological properties. 1,3-Benzodioxole-5-carboxamide has been shown to inhibit the kinases JNK1/2 and p38 MAPK in vitro. It also inhibits the activity of aldehydes (e.g., octadecatrienoic acid) that are involved in inflammatory reactions, as well as amides (e.g., octadecanamide) that are involved in pain perception. This drug may be useful for the treatment of chronic inflammatory diseases such as rheumatoid arthritis or inflammatory bowel disease.</p>

<p>4-Cyanocyclohexane-1-carboxylic acid is a monomer that is used in the production of medicines, such as hydrochloric acid and potassium phosphate. It is also used in the manufacture of corynebacterium and strain specific antibiotic. 4-Cyanocyclohexane-1-carboxylic acid has been shown to be an efficient method for the synthesis of amides, phenylpropionic acids, and aromatic hydrocarbons. As 4-cyanocyclohexane-1-carboxylic acid has a high boiling point and low solubility, it can be used as a synthetic base.</p>

<p>1-Phenylpropane-1,3-diol is a chiral molecule that is assayed using a chromatographic method. It has been shown to be an inhibitor of pancreatic lipase and porcine pancreatic lipase with a potency similar to that of orlistat. This molecule has been shown to inhibit the conversion of l-threonine into l-alanine by competitive inhibition and also inhibits the hydroxy group on the alkyl chain from being oxidized. 1-Phenylpropane-1,3-diol also inhibits the enzyme dehydrogenation, which may cause it to have anti-inflammatory effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,5-Dimethylpyrrole-2-carboxylic Acid is a naturally occurring compound that is found in the marine algae species Ostreococcus tauri. This compound has been shown to have antioxidant properties and to induce apoptosis in cancer cells. 4,5-Dimethylpyrrole-2-carboxylic Acid inhibits the growth of other bacteria by binding to their ribosomes, which prevents protein synthesis and cell division. It also has been shown to be effective against human tumor cells in vitro. 4,5-Dimethylpyrrole-2-carboxylic Acid is a natural antioxidant that can be used as an alternative to synthetic antioxidants such as chlorobenzene.</p>

<p>4-Isothiocyanatobutan-2-one is an antibacterial agent that has been shown to inhibit the growth of bacteria. This compound interacts with bacterial DNA, causing a change in the DNA structure and inhibiting protein synthesis. 4-Isothiocyanatobutan-2-one also inhibits the production of heterocyclic amines and phenothiazine, which are chemicals that are known to cause cancer in laboratory mice. The safety profile of this drug is good, with no ulceration or β-unsaturated ketones found in animal studies.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Dimethyl-1,3-diazinane-2,4-dione (CDD) is an analog of ribulose that has been shown to inhibit the synthesis of both human immunodeficiency virus (HIV) and hepatitis B virus. CDD inhibits the activity of viral reverse transcriptase and protease enzymes. CDD was found to be a potent inhibitor in vitro for HIV and hepatitis B virus. CDD also has pharmacokinetic properties that make it a good candidate for drug development.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Nitrocyclohexanone (2NCH) is a clinical drug that is used in the synthesis of pharmaceuticals. It can be synthesized by dinitrogen tetroxide, hydrochloric acid and magnesium oxide. 2NCH reacts with amines to form lactams. The reaction is catalyzed by organocatalysts such as copper chromite or 5-ht2c. The kinetic of this reaction has been studied extensively and it has been found that the addition of inorganic acids, such as HCl or HNO3, may increase the rate of the reaction.<br>The molecular formula for 2NCH is C8H8O3N2 and its structural formula is shown below:</p>

<p>2-Cyclopentylcyclopentanone (2-CPC) is a cyclopentenone that is produced by the oxidation of 2-cyclohexenylcyclopentanone. 2-CPC has been shown to be genotoxic and can cause damage to DNA, proteins, or cell membranes. This chemical is used in the manufacture of insecticides and herbicides. It also has used as a solvent for polymers, plastics, and coatings. 2-CPC has been found to be toxic at high doses and should not be handled without proper protection.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylbenzimidazole is a non-polar molecule that is found in nature and is related to the flavonoid rutin. 4-Methylbenzimidazole has been shown to inhibit DNA replication and synthesis, as well as protein synthesis. It binds to the polymerase, which prevents it from forming the complementary strand of DNA. This inhibition leads to thermal denaturation of DNA, which prevents the polymerase from binding with the dna template. The low affinity of 4-methylbenzimidazole for dna makes it a potential candidate for anti-HIV drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bibenzylcarboxylic acid is a synthetic retinoid that has been shown to have potent antagonistic effects against the activity of various pro-inflammatory enzymes. It blocks the integrin receptor, which prevents leukocyte adhesion and migration. 2-Bibenzylcarboxylic acid also inhibits protease activity by binding to the active site of the enzyme and preventing substrate binding, as well as dextran sulfate-induced inflammation. 2-Bibenzylcarboxylic acid has been shown to be effective in reducing disease activity in animal models of inflammatory diseases such as rheumatoid arthritis.</p>

<p>Dispiro[3.1.3.1]​decane-​5,​10-​dione is a compound that has not yet been synthesized and its chemical structure is unknown. This product is not available in any catalogues or databases.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Hydroxy-3-(4-hydroxy-3-methoxyphenyl)propan-2-one is a chemical compound that belongs to the group of phenols. It is an intermediate in the production of lignin, which is used in the manufacture of paper and other products. The chemical structure of 1-hydroxy-3-(4-hydroxy-3 methoxyphenyl)propan-2-one can be found in coniferous plants such as pine trees, where it is generated by oxidative coupling of 4 hydroxycinnamaldehyde and 3 hydroxybenzaldehyde.</p>

<p>1-Methoxy-4-nitronaphthalene is a yellow crystalline solid that belongs to the group of naphthalenes. It reacts with deionized water to give nitronaphthalene, which can be detected by ultrafast spectroscopy at constant temperature or by second-order rate constants. The nitro group can be reduced to an amine on treatment with phosphite or diphosphorylated. Nitro groups are also susceptible to nucleophilic attack by acetonitrile and ammonium nitrate, and can be photoreduced to the corresponding amino compound.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N,N,3,5-Tetramethylaniline is a colorless liquid that is soluble in water. It has an aromatic odor and is used as a solvent. N,N,3,5-Tetramethylaniline has been shown to react with 4-dimethylaminobenzoic acid to form a thioxanthone by an irreversible oxidation process. This reaction requires activation energies of 34.2 kcal/mol for the initiation step and 17.1 kcal/mol for termination. The reaction mechanism can be described as:</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Hydroxy-2,2,4,4-tetramethylcyclobutan-1-one is a monomer that is soluble in organic solvents. It can be isolated by centrifugation of the reaction mixture and purified by filtration or recrystallization. 3-Hydroxy-2,2,4,4-tetramethylcyclobutan-1-one has been used as a catalyst for the polymerization of ethylene oxide to polyethers. 3-Hydroxy-2,2,4,4-tetramethylcyclobutan-1-one is also an excellent solvent for ruthenium metal and can be used as a reaction solvent for reactions involving this metal.</p>