Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Phenylthiomorpholine is a drug that is used as an antiarrhythmic agent. This drug has been shown to be effective in the treatment of arrhythmias and can be used to decrease the frequency of ventricular tachycardia, ventricular fibrillation, and atrial fibrillation. 2-Phenylthiomorpholine inhibits the activity of cysteamine, which is an amino acid that plays a major role in the regulation of blood pressure. It also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis, as well as analgesic effects due to its activity on ligand-gated ion channels.

Ethyl 1-benzylpiperidine-2-carboxylate is an organic compound that belongs to the class of benzhydryl compounds. It is a colorless liquid at room temperature and has a boiling point of 60°C. Ethyl 1-benzylpiperidine-2-carboxylate can be synthesized by reacting methanol with piperidine in the presence of aluminum chloride and sodium borohydride in a catalytic amount. The nitrogen atom in this compound is a chiral center, which means it cannot exist as two enantiomers. This product also reacts with chloride to form ethylmagnesium chloride, which is used for the production of aminoalcohols.

Versatile small molecule scaffold

BrettPhos Pd G4 is a versatile polymer used in various research applications. It is commonly used in the field of organic chemistry as a catalyst for reactions involving epoxy chloropropane, clofarabine, iminostilbene, glycine, kavalactone, phenylboronic acid, carbamazepine, and other compounds. This polymer acts as a powerful catalyst and facilitates the synthesis of complex molecules by promoting efficient chemical transformations. Additionally, BrettPhos Pd G4 is known for its inhibitory effects on certain enzymes and can be used as an inhibitor in biochemical studies. Its unique properties make it an essential tool for researchers in the field of organic chemistry and beyond.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Thiazol-5-yl)acetic acid is an antimicrobial that is used as a fungicide. It has been shown to inhibit the growth of Fusarium and Curvularia. 2-(Thiazol-5-yl)acetic acid also has fungicidal activity against Refluxing, butanoic acid, and Oxysporum. This compound has been found to be effective against fungi in a number of different studies. 2-(Thiazol-5-yl)acetic acid inhibits the synthesis of ribosomes by inhibiting mRNA translation, leading to cell death by inhibition of protein synthesis.

Versatile small molecule scaffold

N-Methylquinolin-2-amine is a quinoline derivative that binds to the fatty acid ester of amides, which are found on the surface of cells. It has high specificity for hydroxy groups and is operational in aqueous solutions. N-Methylquinolin-2-amine has been shown to have activity against Alzheimer's disease by binding to the fatty acid ester of amide and blocking the function of ligands. The reaction time can be reduced by adding hydroxy group and alkyl group to the molecule. A molecular orbital diagram shows how this compound reacts with an amide substrate. This drug can be used as a diagnostic or postoperative treatment for Alzheimer's disease.

Versatile small molecule scaffold

2-bromo-1-cyclopentylethan-1-one is a racemic mixture of two enantiomers, 2-bromo-1-(2-methylpropyl)ethanone and 1-(2-methylpropyl)-2-(phenyl)ethanone. The compound has been shown to inhibit cell proliferation in vitro and has been used in the treatment of allergies without any observed side effects. This drug may act by inhibition of the synthesis of L-amino acids or vitamin B6, which are required for cell division. It may also have an effect on alkylating DNA, leading to inhibition of protein synthesis.

Versatile small molecule scaffold