Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N1-(5-Bromo-2-pyridinyl)-N2,N2-dimethyl-1,2-ethanediamine is a potent inhibitor of PI3K and p38 MAPK. It also has anti-inflammatory properties through the inhibition of alveolar macrophages. This compound can be used to treat idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease (COPD), both of which are caused by the excessive accumulation of extracellular matrix proteins. N1-(5-Bromo-2-pyridinyl)-N2,N2-dimethyl-1,2-ethanediamine is also an important intermediate in the synthesis of other compounds that have been shown to be potent modulators for Alzheimer's disease and cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Furo[3,2-b]pyridine-2-carboxylic acid is a borohydride diester with the molecular formula CHB(OCH)CHB(OH)COOH. It is created by the decarboxylation of furopyridine (a compound of the class of furopyridines), followed by hydrolysis and cyclization. It can be synthesized by reacting ethyl bromoacetate with phosphoric acid and then hydrolyzed to yield a hydroxy derivative. Furo[3,2-b]pyridine-2-carboxylic acid is used in organic chemistry as an intermediate for other compounds, such as pharmaceuticals and pesticides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Benzyl-2-azabicyclo[2.2.1]hept-5-ene is a reactive molecule that belongs to the class of carbocyclic nucleosides. It reacts with a variety of functional groups, including amide groups and iminium groups, which makes it a useful monomer for peptidomimetic synthesis, as well as copolymerization with other monomers. This compound yields high molecular weight polymers with amide and iminium functionalities in good yield, making it an attractive polymer candidate for drug delivery and biomedical applications.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-{[(tert-butoxy)carbonyl]amino}propanoate is a chiral compound that has been synthesized in a gramicidin-based process. This process was optimized to yield the desired stereoselectivity and enantiopurity. The synthesis of Methyl 2-{[(tert-butoxy)carbonyl]amino}propanoate involves a three step reaction that starts with the condensation of L-alanine and methyl 2-(2,4,6-trimethoxyphenyl)acetate. In the second step, an aminoester intermediate is formed by reacting this condensation product with tert-butyl bromoacetate. The final step involves the hydrolysis of this aminoester intermediate to form Methyl 2-{[(tert-butoxy)carbonyl]amino}propanoate. Methyl 2-[(tert-but</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>